Clinical trials: Musculoskeletal Injury Trauma
Myopathy, Muscle Weakness
Reliability of Cardiac Troponins for the Diagnosis of Myocardial Infarction in the Presence of Skeletal Muscle Disease
Visits to the emergency department (ED) for chest pain are extremely common and require a safe, rapid and efficacious treatment algorithm to exclude a possible AMI.
- Conditions
- Myopathy, Muscle Weakness, Muscle Damage, Muscle Spasticity
- Trial name
- H&M (NCT03660969)
- Where
- 5 sites in Austria, Switzerland
- Volunteers
- 797 people
- Sponsor
- University Hospital, Basel, Switzerland
Musculoskeletal Injury
Return to Baseball After BFR Therapy for Shoulder Injury
The literature is limited on whether BFR therapy provides improved return to function after acute rotator cuff or biceps rehabilitation in non-operative cases, and whether there is a clear mechanism of action in musculotendinous…
- Trial name
- NCT04248413
- Testing
- Blood Flow Restriction Therapy, Standard physical rehabilitation
- Sponsor
- Wake Forest University Health Sciences
Vestibular Schwannoma, Acoustic Neuroma
Auditory Nerve Test System During Vestibular Schwannoma Resection
The Auditory Nerve Test System (ANTS) is a novel device that stimulates the auditory nerve much like a cochlear implant. The purpose of this study is to demonstrate feasibility of the ANTS during translabyrinthine surgery for…
- Conditions
- Vestibular Schwannoma, Acoustic Neuroma, Sensorineural Hearing Loss, Asymmetric Sensorineural Hearing Loss
- Trial name
- ANTS (NCT04241679)
- Testing
- Auditory Nerve Test System
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Washington University School of Medicine
Stroke, Brain Injuries
Comparative Efficacy of Three Preparations of Botox-A in Treating Spasticity
The study seeks to compare the effectiveness of three preparations of BOTOX-A® in treating muscle tightness and spasms in the feet and ankles of people with stroke.
- Conditions
- Stroke, Brain Injuries, Spasticity
- Trial name
- NCT00178646
- Testing
- Botox
- Where
- 2 sites in United States
- Volunteers
- 33 people
- Sponsor
- The University of Texas Health Science Center, Houston
Spinal Cord Injuries
Pulsed Magnetic Stimulation - Managing Spasticity in Spinal Cord Injury
Spasticity (tightening, spasming and/or contractions of muscles) is a commonly encountered consequence of injuries to the central nervous system.
- Trial name
- OsStim (NCT04015362)
- Testing
- Sub-threshold intermittent pulsed magnetic stimulation
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust
Osteo Arthritis Knee
Reliability and Validity of Turkish Version of Knee Injury and Osteoarthritis Outcome Score-12
Approximately 120 patients who have been diagnosed with knee osteoarthritis but have not previously operated due to this disease and who are in Kellgren Lawrence stage 2 and 3 will be compared with the KOOS scale and Short…
- Trial name
- KOOS-12 (NCT04277676)
- Where
- Turkey (Türkiye)
- Volunteers
- 135 people
- Sponsor
- Bahçeşehir University
Ankle Sprains, Instability, Joint
Arthroscopic Versus Open Brostrom for Ankle Instability
Background: Ankle sprains are among the most prevalent lesions in primary care. A substantial number of these ligament lesions will develop ankle instability and require a surgical procedure.
- Conditions
- Ankle Sprains, Instability, Joint, Ligament Injury, Surgery
- Trial name
- NCT03643926
- Testing
- Arthroscopic Brostrom, Open Brostrom
- Where
- 2 sites in Brazil
- Volunteers
- 98 people
- Sponsor
- Federal University of São Paulo
Muscle Weakness
Effect of Sequencing on Outcome Measures
This pilot study will examine the effect of testing order on test outcomes for measures of strength, dynamic balance, and movement quality.
- Trial name
- NCT06445491
- Testing
- Control order, Randomized sequence
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center Shreveport
Shoulder Injuries, Shoulder Pain
Nordic Throwing Shoulder Project (NTS - Project)
As a part of the Olympic program and with 150 countries in the international Handball Federation team handball has become a worldwide popular sport.
- Conditions
- Shoulder Injuries, Shoulder Pain, Injury Prevention, Kinematics
- Trial name
- NCT04056078
- Where
- 2 sites in Denmark, Norway
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nord University
Ankle Sprains, Instability, Joint
The Clinical Outcomes of the Modified Broström vs Anatomic Reconstruction Operation in CLAI and GJL
Investigators designed this prospective cohort study to compare the clinical outcomes of modified Broström operation and anatomical reconstruction for the treatment of CLAI and GJL.
- Conditions
- Ankle Sprains, Instability, Joint, Joint Hypermobility
- Trial name
- NCT05196906
- Testing
- Modified Broström operation and anatomic reconstruction operation
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking University Third Hospital
Neck Pain
Healing With Venlafaxine After Injury (HELP)
Purpose: The purpose of this study is to demonstrate the potential efficacy of venlafaxine administration in reducing acute and chronic musculoskeletal pain in individuals presenting to the ED for evaluation after motor vehicle…
- Trial name
- HELP (NCT01716377)
- Testing
- Venlafaxine
- Where
- 3 sites in United States
- Volunteers
- 20 people
- Sponsor
- Rhode Island Hospital
Musculoskeletal Strain, Musculoskeletal Sprain
Pain Management Following Musculoskeletal Injury
Musculoskeletal sprain/strain injuries and disorders (MSID) have a major impact on health, quality of life and societal productivity.
- Conditions
- Musculoskeletal Strain, Musculoskeletal Sprain, Injury of Musculoskeletal System
- Trial name
- NCT01689675
- Testing
- Computer based pain management
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- Johns Hopkins University
Pulmonary Disease, Chronic Obstructive, Amyotrophic Lateral Sclerosis
European Home Mechanical Ventilation Registry
The European Home Mechanical Ventilation Registry (EHMVR) will enable a thorough evaluation of HMV by documenting the characteristics of HMV patients and their treatment.
- Conditions
- Pulmonary Disease, Chronic Obstructive, Amyotrophic Lateral Sclerosis, Spinal Cord Injury, Muscular Dystrophies
- Trial name
- EHMVR (NCT02315339)
- Where
- Germany
- Volunteers
- 37 people
- Sponsor
- ResMed
Musculoskeletal Injury
NSAID Use and Healing After Tibia Fractures and Achilles Tendon Ruptures
Rationale: The Emergency Department (ED) typically serves as the front line for patients with acute fractures and tendon ruptures. Pain control for these patients is an essential task of the ED physician.
- Trial name
- NCT03880981
- Testing
- Ibuprofen 600 mg, Acetaminophen
- Volunteers
- 456 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Ankle Injuries, Sprains and Strains
Impact of Hyperarch Fascia Training on Ankle Health and Exercise Performance
The purpose of this clinical trial is to evaluate whether the Hyperarch Fascia Training (HFT) program can reduce ankle pain and improve jump performance in active adults aged 20-45 with a history of ankle sprains.
- Conditions
- Ankle Injuries, Sprains and Strains, Joint Instability
- Trial name
- NCT06959472
- Testing
- Hyperarch Fascia Training
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Applied Science & Performance Institute
Fall Injury, Hip Fractures
Fall, Fracture and Frailty
This project aims to improve the global outcome for an aging individual after a traumatic fall, through identifying conditions contributing to a fall and promoting recovery and rehabilitation.
- Conditions
- Fall Injury, Hip Fractures, Risk Reduction, Osteoporosis, Osteopenia
- Trial name
- FFF (NCT05712252)
- Where
- Sweden
- Volunteers
- 1,200 people
- Sponsor
- Region Skane
Spasticity as Sequela of Stroke, Spastic Cerebral Palsy
Radiosurgery Treatment for Spasticity Associated With Stroke, SCI & Cerebral Palsy
A scientific study is being done to test a special treatment for people who have spasticity or tight muscles. This treatment is called "stereotactic radiosurgery dorsal rhizotomy." It uses very accurate beams of radiation to…
- Conditions
- Spasticity as Sequela of Stroke, Spastic Cerebral Palsy, Spasticity, Muscle
- Trial name
- SPASM (NCT06070233)
- Testing
- stereotactic radiosurgery (SRS) dorsal root rhizotomy radiomodulation
- Where
- 2 sites in United States
- Volunteers
- 22 people
- Sponsor
- Ohio State University
Acute Kidney Injury, Intra-Abdominal Hypertension
Cumulative Intra-Abdominal Pressure Burden and Acute Kidney Injury After Emergency Abdominal Surgery
The goal of this observational study is to learn whether increased pressure inside the abdomen over time is associated with acute kidney injury in adults receiving intensive care after emergency abdominal surgery.
- Trial name
- IAP-AKI (NCT07891026)
- Testing
- Serial Intra-Abdominal Pressure Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Ugur Duman
Spinal Cord Injuries, Upper Extremity Problem
Upper Extremity Pathologies in Spinal Cord Injuries
This study aims to determine the relationship between upper extremity pathologies and demographic data, duration of manual wheelchair use, duration of injury, physical examination and musculoskeletal ultrasound measurements in…
- Conditions
- Spinal Cord Injuries, Upper Extremity Problem, Musculoskeletal Pain
- Trial name
- NCT06278740
- Testing
- Musculoskeletal Ultrasound
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Afyonkarahisar Health Sciences University
Osteoarthritis, Knee, Anterior Cruciate Ligament Injuries
Vibration and Post-traumatic Osteoarthritis Risk Following ACL Injury
The goal of this randomized clinical trial is to evaluate the effects of vibration on factors related to the risks of post-traumatic knee osteoarthritis and secondary anterior cruciate ligament (ACL) injury in individuals who…
- Conditions
- Osteoarthritis, Knee, Anterior Cruciate Ligament Injuries, Post-traumatic Osteoarthritis, Quadriceps Muscle Atrophy
- Trial name
- NCT04875052
- Testing
- Experimental: Whole Body Vibration, Experimental: Local Muscle Vibration, Standard ACL Rehabilitation
- Where
- 2 sites in United States
- Volunteers
- 114 people
- Sponsor
- University of North Carolina, Chapel Hill