Clinical trials: Musculoskeletal Injury Trauma
Athletic Injuries, Sports Injury Prevention
Evaluation of Injury Risk Factors and Effects of Individualized Exercise Program in Basketball and Volleyball Athletes
This study aims to identify injury risk factors using a clinical/functional test battery in university basketball and volleyball athletes, to develop individualized exercise prescriptions for athletes scoring below established…
- Conditions
- Athletic Injuries, Sports Injury Prevention, Musculoskeletal Injury
- Trial name
- IRISPORT (NCT07521215)
- Testing
- Test-Specific Individualized Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Spasticity, Muscle, Spinal Cord Injuries
Vibrotactile Coordinated Reset for Spasticity After Spinal Cord Injury
The purpose of our study is to evaluate vibrotactile Coordinated Reset (vCR) and its effects on spasticity symptoms in incomplete spinal cord injured patients. vCR will be administered with a device called the Stanford CR Glove.
- Trial name
- NCT06290609
- Testing
- Vibrotactile Coordinated Reset
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Stanford University
Surgery, Critical Illness
Sedation Optimisation Strategy (S.O.S.) Ventilation
Use of sedatives and analgesics is common in mechanically ventilated patients hospitalized in Intensive Care Unit (ICU). That is called " sedation " and aimed to reduce both pain and anxiety and also to allow an effective and…
- Conditions
- Surgery, Critical Illness, Mechanical Ventilation Complication, Organ Dysfunction Syndrome
- Trial name
- NCT01486121
- Testing
- Therapy strategy
- Where
- 3 sites in France
- Volunteers
- 140 people
- Sponsor
- University Hospital, Montpellier
Amyotrophic Lateral Sclerosis, Brainstem Stroke
Optimizing BCI-FIT: Brain Computer Interface - Functional Implementation Toolkit
This project adds to non-invasive BCIs for communication for adults with severe speech and physical impairments due to neurodegenerative diseases.
- Conditions
- Amyotrophic Lateral Sclerosis, Brainstem Stroke, Muscular Dystrophies, Parkinson's Disease and Parkinsonism
- Trial name
- BCI-FIT (NCT04468919)
- Testing
- BCI-FIT multi-modal access, BCI-FIT adaptive signal modeling, BCI-FIT active querying
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Rotator Cuff Tendinopathy
PAin During Shoulder Exercise
Overuse shoulder injuries such as rotator cuff (RC) tendinopathy are common with a prevalence estimated to be 14% in the general population of which 23% of the working population with shoulder problems are sick listed.
- Trial name
- PASE (NCT05124769)
- Testing
- Pain Allowing Program (PAllow), Pain Avoiding Program (PAvoid)
- Where
- Denmark
- Volunteers
- 84 people
- Sponsor
- Bispebjerg Hospital
Physical Therapy Direct Access, Physical Therapy Primary Care
Effectiveness of Two Different Entry Portal Pathways Into Primary Care for Musculoskeletal Injury
This study aims to compare the self-report functional outcome measures, medical readiness and healthcare utilization (overall cost of imaging, prescription medications for pain, and follow-up visits) of soldiers with…
- Trial name
- NCT02726802
- Testing
- physical therapy vs. primary care interventions
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Reynolds Army Community Hospital
Carpal Tunnel Syndrome, Ulnar Nerve Injury
New 3D Printed Wrist Orthosis
In order to offer a new product improving the healing and/or rehabilitation of injuries or injuries to the wrist and hand, Médicus is seeking to develop a new orthosis for the wrist and hand by 3D printing.
- Conditions
- Carpal Tunnel Syndrome, Ulnar Nerve Injury, Rhizarthrosis, Tendinopathy, Thumb
- Trial name
- NCT05597930
- Testing
- Wrist and Thumb orthosis
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- TOPMED
Muscular Dystrophy, Duchenne, Orthotic Devices
The Effect of a Muscle-mimicking, Fabric-type Shoulder Orthosis on Functional Movements of the Upper Limb in Patients With Neuromuscular Disorder
The goal of this clinical trial is to investigate the effect of a muscle-mimicking, fabric-type shoulder orthosis on functional movements of the upper limb in patients with neuromuscular disorder.
- Conditions
- Muscular Dystrophy, Duchenne, Orthotic Devices, Upper Extremity, Neuromuscular Diseases (NMD)
- Trial name
- NCT06363357
- Testing
- Shoulder orthosis
- Where
- South Korea
- Volunteers
- 8 people
- Sponsor
- Seoul National University Hospital
Traumatic Brain Injury
Pilot, Proof-of-Concept Study of Sublingual Tizanidine in Children With Chronic Traumatic Brain Injury (TBI)
Nightly administration of a unique, sublingual (under the tongue) formulation of tizanidine, a known anti-spasticity medication, has been shown in a previous study to improve sleep and next-day functioning in CP (cerebral palsy)…
- Trial name
- NCT00287157
- Testing
- Sublingual Tizanidine HCl
- Where
- Israel
- Volunteers
- 5 people
- Sponsor
- Teva GTC
Spasticity, Cerebrovascular Accident
Efficacy and Safety Study of MYOBLOC® in the Treatment of Adult Upper Limb Spasticity
Phase 2/3, randomized, double-blind, placebo-controlled, single-treatment, multicenter trial assessing the efficacy and safety of MYOBLOC for the treatment of upper limb spasticity in adults followed by an open-label extension…
- Conditions
- Spasticity, Cerebrovascular Accident, Multiple Sclerosis, Traumatic Brain Injury
- Trial name
- NCT04815967
- Testing
- Phase 2; Low Dose MYOBLOC (10,000 Units), Phase 2; High Dose MYOBLOC (20,000 Units), Phase 3; MYOBLOC
- Where
- 9 sites in United States, Hungary and 1 more
- Volunteers
- 32 people
- Sponsor
- Solstice Neurosciences, LLC, a subsidiary of MDD US Operations, LLC
Gait Impairment, Cerebral Palsy (CP)
Clinical Investigation to Validate the Safety and Performance of the ABLE Kids Device in Pediatric Patients With Neurological Gait Disorders in a Clinical Setting
The primary objective of the study is to validate the safety and clinical performance of the ABLE Kids device in pediatric patients with neurological gait disorders or muscular weakness during a 10-session gait training program…
- Conditions
- Gait Impairment, Cerebral Palsy (CP), Neuromuscular Diseases (NMD), Spinal Cord Injuries (SCI)
- Trial name
- NCT07745712
- Testing
- ABLE Kids
- Where
- Spain
- Volunteers
- 15 people
- Sponsor
- ABLE Human Motion S.L.
Instability, Joint, Ankle Sprains
Italian Version of The Cumberland Ankle Instability Tool (CAIT)
Study Design: Evaluation of the psychometric properties of a translated, culturally adapted questionnaire. Objective: Translating, culturally adapting, and validating the Italian version of the Cumberland Ankle Instability Tool…
- Conditions
- Instability, Joint, Ankle Sprains, Ankle Injuries, Sport Injury
- Trial name
- CAIT-I (NCT04644601)
- Where
- Italy
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- University of Bologna
Alveolar Ridge Trauma, Bone Resorption
Biomaterial to Counteract Ridge Reduction Following the Removal of Multiple Adjacent Teeth.
An open, prospective, randomized, multicenter study focused on the ridge diminution in case of grafting of fresh extraction sockets with Bio-Oss Collagen, Bio-Gide (Geistlich Pharma, Wolhusen, Switzerland), placing Dentsply…
- Trial name
- Biomaterial (NCT02903667)
- Testing
- Bone grafting
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Institute Franci
Lumbar Spine Stenosis, Lumbar Disc Herniation
Dynamic Compliance-Guided Ventilation in Lumbar Surgery
Postoperative pulmonary complications are a frequent cause of morbidity following lumbar stabilization surgery. Conventional ventilation strategies may not adequately reflect intraoperative changes in respiratory mechanics…
- Conditions
- Lumbar Spine Stenosis, Lumbar Disc Herniation, Ventilator-Induced Lung Injury, Postoperative Complications
- Trial name
- NCT07349719
- Testing
- Dynamic Compliance Guided Ventilation, Standard Ventilation
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Ankara City Hospital Bilkent
Muscle Atrophy, ACL Reconstruction
Testosterone Administration and ACL Reconstruction in Men
This study is being done to test whether taking testosterone can prevent loss of muscle mass and strength due to anterior cruciate ligament (ACL) reconstructive surgery.
- Conditions
- Muscle Atrophy, ACL Reconstruction, Trauma, Osteoarthritis
- Trial name
- TACL (NCT01595581)
- Testing
- Testosterone
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Southern California
Spinal Cord Injuries, Spine Disease
Temporary Inactivation of Strong Muscle Sensation to Improve Rehabilitation Interventions in SCI
The investigators are conducting a research study to try to improve rehabilitation interventions for individuals with spinal cord injury (SCI).
- Conditions
- Spinal Cord Injuries, Spine Disease, Stroke
- Trial name
- NCT05589402
- Testing
- Lidocaine Cream 5%, Rehabilitation Movement Training
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Texas Rio Grande Valley
Tetraplegia, Tetraplegia/Tetraparesis
[BrainConnexion] - Neurodevice Phase I Trial
This study aims to evaluate the safety of a wireless implantable neurodevice microsystem in tetraplegic patients, as well as the efficacy of the electrodes for long-term recording of neural activities and the successful control…
- Conditions
- Tetraplegia, Tetraplegia/Tetraparesis, Spinal Cord Injuries, Amyotrophic Lateral Sclerosis
- Trial name
- NCT03811301
- Testing
- BrainConnexion
- Where
- Singapore
- Volunteers
- 5 people
- Sponsor
- National Neuroscience Institute
Radius; Deformity, Hip Osteoarthritis
Clinical Evaluation and Cost-effectiveness Analysis of 3D Digital Surgery in Traumatology
Digital surgery, in combination with patient specific instrumentation (PSI) is being used more and more in traumatology due to its proven benefits and applications.
- Conditions
- Radius; Deformity, Hip Osteoarthritis, Hip Arthritis, Hip Arthropathy
- Trial name
- NCT06603831
- Testing
- patients treated using 3D technology and Patient-Specific Instrumentation, Patients treated with conventional surgery, without using 3D technology
- Where
- Spain
- Volunteers
- 180 people
- Sponsor
- Corporacion Parc Tauli
Stroke, Walking, Difficulty
Agonist and Antagonist Muscle Activations in the Lower Limbs During Walking After Central Nervous System Injury
The retrospective study investigates the part of responsibility of neuromuscular disorders associated with chronic hemiparesis in walking impairment.
- Conditions
- Stroke, Walking, Difficulty, Spasticity/Paresis
- Trial name
- NEUROGAIT (NCT06107556)
- Testing
- Gait analysis
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Henri Mondor University Hospital
Brain Injury, Brain Injury, Vascular
Early Myofascial Manual Treatment in Subjects With Spasticity Following Acquired Brain Injury
Spasticity is characterized by an increase in muscle tone that is velocity-dependent and caused by the exaggeration of the stretch reflex.
- Conditions
- Brain Injury, Brain Injury, Vascular, Brain Injuries, Traumatic
- Trial name
- MyosABI (NCT06898242)
- Testing
- Manual myofascial treatment direct to upper and lower limb, Rehabilitative treatment following rehabilitation project
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS