Clinical trials: Musculoskeletal Symptom
Gout, Hyperuricemia
A Randomized, Double-Blind, Dose-Response Study of the Safety and Uric Acid Effects of Oral Ulodesine Added to Allopurinol in Subjects With Gout and Concomitant Moderate Renal Insufficiency
To evaluate the overall safety and tolerability of ulodesine when combined with allopurinol in subjects with moderate renal insufficiency.
- Conditions
- Gout, Hyperuricemia, Arthritis, Joint Disease
- Trial name
- NCT01407874
- Testing
- Ulodesine (BCX4208) 5 mg, Ulodesine (BCX4208) 10 mg
- Where
- 10 sites in United States
- Volunteers
- 20 people
- Sponsor
- BioCryst Pharmaceuticals
PARKINSON DISEASE (Disorder)
Virtual tES Device Treatment for Parkinson's Disease Motor Symptoms
This study tests a new, non-invasive brain stimulation device called Sphere V3.0 to help improve movement problems in people with Parkinson's disease.
- Trial name
- NCT07182058
- Testing
- Transcranial Electrical Stimulation Device
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- U: The Mind Company
Osteonecrosis, Osteo Arthritis Knee
MOTO Post-marketing Surveillance Study
The prospective, multicentric, observational study has the aims to monitor the performance of the MOTO medial unicompartmental knee system in the treatment of patients with knee disease requiring a UKA.
- Trial name
- NCT04072055
- Testing
- MOTO Medial
- Where
- 2 sites in Belgium
- Volunteers
- 150 people
- Sponsor
- Medacta International SA
Turner Syndrome
Somatropin Treatment to Final Height in Turner Syndrome
A randomized, controlled trial in girls with Turner syndrome at least 7 years old and younger than 13 at study entry, to determine the efficacy and safety of Humatrope (somatropin) treatment in promoting linear growth to final…
- Trial name
- GDCT (NCT00191113)
- Testing
- Somatropin, Ethinyl estradiol, Medroxyprogesterone acetate
- Where
- 14 sites in Canada
- Volunteers
- 154 people
- Sponsor
- Eli Lilly and Company
Gout, Hyperuricemia
The Effect of Naproxen on the Pharmacokinetic Profile of LC350189 in Healthy Adults
This is a Phase 1, open-label, fixed-sequence, 3-period, 2-way drug interaction study designed to assess the pharmacokinetics, pharmacodynamics, safety, and tolerability of LC350189 and Naproxen when administered alone and in…
- Trial name
- NCT04139824
- Testing
- Xanthine Oxidase Inhibitor, nonsteroidal anti-inflammatory drug
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- LG Chem
Lumbar Disc Herniation
Effect of Decompression With and Without ELDOA in Lumber Disc Protrusion Patients
The study will be conducted to determine the effects of spinal decompression with and without ELDOA in patients of lumbar disc protrusion.
- Trial name
- ELDOA (NCT04930523)
- Testing
- Elongation Longitudinaux Avec Decoaption Osteo Articulaire, Decompression
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- Aqua Medical Services (Pvt) Ltd
Muscle Spasticity
Spasticity Registry Evaluating Epidemiology, Treatment Patterns and Clinical Needs
This study will examine the epidemiology (incidence and control of a disease), burden, clinical need, and treatment patterns of spasticity in patients with a diagnosis of Cerebral Palsy (CP), Multiple Sclerosis (MS), Stroke…
- Trial name
- STRETCh (NCT02145650)
- Testing
- No Intervention
- Where
- United States
- Sponsor
- Allergan
Osteoarthritis (OA), Longevity
Registry of Outcomes of Dezawa MuseCells®
The goal of this observational study is to learn about the long-term effects of Dezawa MuseCells to treat various diseases. The Primary Goal: What is the short-term and long- term outcomes of Dezawa Musecells? Participants…
- Conditions
- Osteoarthritis (OA), Longevity, Wound Care, Pain
- Trial name
- NCT07645989
- Testing
- MuseCell Treatment
- Where
- 2 sites in United States, Mexico
- Volunteers
- 5,000 people
- Sponsor
- MuseCell Innovations Pte LTD
Total Hip Arthroplasty, Osteoarthritis, Hip
Corin MiniHip and Trinity Cup Clinical Surveillance Study
The aim of the study is to provide long term follow up data on the performance and safety of the Corin MiniHip and Trinity acetabular cup over a 10-year period.
- Conditions
- Total Hip Arthroplasty, Osteoarthritis, Hip, Traumatic Arthritis of Hip, Rheumatoid Arthritis of Hip
- Trial name
- NCT05186168
- Testing
- MiniHip Stem, Trinity Acetabular Cup System
- Volunteers
- 546 people
- Sponsor
- Corin
Osteoarthritis, Sarcopenia
To Investigate Effects of Amway Bundle Combination of Products on Osteoarthritis & Sarcopenia
The goal of this interventional study is to evaluate the effects of bundle combination of Amway All-plant protein booster with Nutrilite Lifestyle guideline and/or EMS (Electric Muscle Stimulation) device on Osteoarthritis \&…
- Trial name
- NCT05872360
- Testing
- Bundle Group 1 with Nutrilite Lifestyle, Bundle Group 2 without Nutrilite Lifestyle, Control Group 1
- Where
- 2 sites in China
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Amway (China) R&D Center
Chronic Pain, Knee Pain Chronic
HFIT Versus TENS Study for Chronic Low Back and Knee Pain
A high-frequency impulse therapy (HFIT) device (Enso, San Francisco, CA) is a portable device for the treatment of musculoskeletal pain.
- Conditions
- Chronic Pain, Knee Pain Chronic, Back Pain, Low
- Trial name
- NCT05821530
- Testing
- HFIT, TENS, Control
- Where
- United States
- Volunteers
- 325 people
- Sponsor
- Hinge Health, Inc
Osteoarthritis, Avascular Necrosis
Trinity™ BIOLOX Delta™ CoC THR Multi-center Study
To demonstrate the safety and effectiveness of the Trinity™ BIOLOX delta™ Ceramic-on-Ceramic Total Hip System in comparison to the Trinity™ Acetabular Hip System,which is FDA cleared for use in the U.S.
- Conditions
- Osteoarthritis, Avascular Necrosis, Rheumatoid Arthritis, CDH
- Trial name
- NCT01921309
- Testing
- Trinity CoC Total Hip System, Trinity Ceramic-on-Poly THR
- Where
- 10 sites in United States, United Kingdom
- Volunteers
- 342 people
- Sponsor
- Corin
Sporadic Inclusion Body Myositis
An Extension Study of the Efficacy, Safety and Tolerability of BYM338 (Bimagrumab) in Patients With Sporadic Inclusion Body Myositis Who Previously Participated in the Core Study CBYM338B2203
This extension study will provide data to further evaluate the efficacy, safety, and tolerability of three doses of BYM338 and to assess the long-term effects of BYM338 in patients with sporadic inclusion body myositis.
- Trial name
- NCT02573467
- Testing
- Bimagrumab
- Where
- 38 sites in United States, Australia and 8 more
- Volunteers
- 211 people
- Sponsor
- Novartis Pharmaceuticals
Arthritis, Rheumatoid
Safety and Efficacy of TAK-715 in Subjects With Rheumatoid Arthritis
The purpose of this study is to evaluate the safety and efficacy of TAK-715, twice daily (BID), in the treatment of rheumatoid arthritis signs and symptoms in patients with a partial response to methotrexate.
- Trial name
- NCT00760864
- Testing
- TAK-715 and methotrexate, Methotrexate
- Volunteers
- 432 people
- Sponsor
- Takeda
Weakness, Muscle
Effects of INDUS810 on Body Composition, Muscular Performance, and Training Adaptations
The purpose of this 12-week, interventional study is to determine the effects of oral supplementation with Indus810 (dietary supplement with active ingredient Fenugreek) on body composition, muscular performance, and training…
- Trial name
- NCT03850106
- Testing
- Indus810
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- The Center for Applied Health Sciences, LLC
Osteoarthritis, Rheumatoid Arthritis
A Clinical Investigation of the Discovery™ Elbow System
The purpose of this study is to perform a five-year, multi-center prospective evaluation of the Discovery™ Elbow System for outcome and durability.
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Avascular Necrosis, Humeral Fractures
- Trial name
- NCT00698867
- Where
- 4 sites in United States
- Volunteers
- 118 people
- Sponsor
- Biomet Orthopedics, LLC
Healthy Volunteers, Muscle Fatigue
Effects of Recoverben® on Recovery After Exhaustive Exercise
The aim of the study is to investigate a pre and post workout supplementation (15 days) with Recoverben® , a Aloysia citriodora extract on recovery after exhaustive exercise.
- Conditions
- Healthy Volunteers, Muscle Fatigue, Muscle Soreness
- Trial name
- NCT02923102
- Testing
- Aloysia citriodora extract, Maltodextrin
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Vital Solutions GmbH
Arthritis, Osteoarthritis
Tanezumab in Osteoarthritis of the Knee
Test the efficacy and safety of 3 doses in Osteoarthritis of the knee in patients.
- Trial name
- NCT00733902
- Testing
- tanezumab
- Where
- 82 sites in United States
- Volunteers
- 697 people
- Sponsor
- Pfizer
Osteoarthritis of the Knee
Study of FX006 vs Normal Saline in Patients With Osteoarthritis of the Knee
The purpose of this study was to assess the magnitude and duration of pain relief of a single IA injection of 2 doses (16 and 32 mg) of FX006, an extended-release formulation of TCA, relative to normal saline (placebo control).
- Trial name
- NCT02116972
- Testing
- FX006 32 mg, FX006 16 mg
- Where
- 44 sites in United States, Canada
- Volunteers
- 310 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Osteoarthritis
To Determine the Safety, Tolerability, Pharmacokinetics and Effect on Pain of a Single Intra-articular Administration of Canakinumab in Patients With Osteoarthritis in the Knee
The purpose of this study was to determine whether, in patients with mild to moderate knee osteoarthritis, canakinumab is safe and tolerable when injected intra-articularly.
- Trial name
- NCT01160822
- Testing
- Canakinumab, Naproxen
- Where
- 13 sites in United States, Finland and 2 more
- Volunteers
- 169 people
- Sponsor
- Novartis Pharmaceuticals
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