Clinical trials: Musculoskeletal Symptom
Postpoliomyelitis Syndrome
Modafinil to Treat Fatigue in Post-Polio Syndrome
This study, conducted at the Walter Reed Army Medical Center, the National Rehabilitation Hospital, and the National Institutes of Health, will examine whether the drug Modafinil can decrease fatigue in patients with post-polio…
- Trial name
- NCT00067496
- Testing
- Modafinil
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Shoulder Pain Back Pain Postpartum Period, Back Pain
Effects of Body Mechanics Training on Shoulder-Back Pain and Breastfeeding Ergonomics in Breastfeeding Mothers
The research will be conducted as a randomized controlled trial and mothers in the intervention group will receive training on posture correction,breastfeeding positions, and shoulder and back muscle strengthening movements.
- Conditions
- Shoulder Pain Back Pain Postpartum Period, Back Pain, Postpartum Period
- Trial name
- RCT (NCT07104227)
- Testing
- body mechanics training, to inform
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Ege University
Aortic Valve Disease, Artificial Heart Valves
Post-market Clinical Monitoring of the Safety and Efficacy of the Aortic Valve Bioprothesis
The goal of this multicenter prospective cohort study is to evaluate the long-term safety and efficacy of clinical outcomes of aortic valve replacement using the "TiAra" prosthesis with or without concomitant procedures.
- Trial name
- TiAra (NCT05998694)
- Where
- Russia
- Volunteers
- 2,000 people
- Sponsor
- Closed Joint-Stock Company NeoCor
Myofascial Pain Syndrome, Breast Cancer
Myofascial Pain Syndrome in Patients With Breast Cancer-related Lymphedema
The goal of this observational study is to determine the relationship between Lymphedema and Myofascial Pain Syndrome in Breast Cancer Patients.
- Conditions
- Myofascial Pain Syndrome, Breast Cancer, Breast Cancer Female, Lymphedema
- Trial name
- NCT06012786
- Testing
- Diagnostic Criteria of Myofascial Pain Syndrome, The Physical Examination of Trigger Points and Pain-Pressure Threshold Measurement With an Algometer, Hand Grip Test
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Chronic Pain, Osteoarthritis
Evaluation of Effectiveness and Tolerability of Tapentadol Hydrochloride in Subjects With Severe Pain Due to Osteoarthritis Taking Either WHO Step I or Step II Analgesics or no Regular Analgesic
The main objective of the study is to evaluate the effectiveness, tolerability, and safety of tapentadol hydrochloride prolonged release in participants suffering from severe chronic pain due to osteoarthritis of the knee who are…
- Trial name
- NCT00983073
- Testing
- Tapentadol
- Where
- 24 sites in France, Germany and 3 more
- Volunteers
- 224 people
- Sponsor
- Grünenthal GmbH
Shoulder Pain
Reliability and Validity of Goniometric iPhone Applications
The purpose of this study is to determine the test-retest and inter-rater reliability and concurrent validity of two iPhone goniometric applications in the measurement of active shoulder external rotation as compared to a…
- Trial name
- NCT01629641
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Texas Woman's University
TMJ Disorder, Myofacial Pain
Comparison of Cannabinoids to Placebo in Management of TMJ Pain and Myofascial Pain in the TMJ Region
The aim of this study is to determine whether the cannabinoids taken orally in the form of cannabidiol (CBD oil-a major non-psychoactive component of marijuana) vs placebo (hemp oil) will provide pain relief and improved jaw…
- Conditions
- TMJ Disorder, Myofacial Pain, TMD
- Trial name
- NCT04298554
- Testing
- CBD Oil, Hemp Oil
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Weill Medical College of Cornell University
Overweight and/or Obesity
Effects of Whole-Body High-Intensity Interval Training on Fitness in Overweight Adults
This study aims to evaluate the effects of a supervised whole-body high-intensity interval training (WB-HIIT) program on physical fitness and health outcomes in adults with overweight and obesity.
- Trial name
- WB-HIIT (NCT07582718)
- Testing
- Whole-Body High-Intensity Interval Training (WB-HIIT)
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Université Libre de Bruxelles
Knee Osteoarthritis
Effects of Carbon Dioxide Infrared Laser Moxibustion on Pain and Function in Knee Osteoarthritis
Knee osteoarthritis is a prevalent degenerative joint disorder characterized by chronic knee pain, stiffness, reduced range of motion, and limitations in daily functional activities.
- Trial name
- CILM-KOA (NCT07423182)
- Testing
- Exercise Program for Knee Osteoarthritis, CO2 Infrared Laser Moxibustion (CILM)
- Where
- Pakistan
- Volunteers
- 68 people
- Sponsor
- University of Lahore
Pierre Robin Syndrome, Cleft Palate
Postoperative Complications After Cleft Palate Closure in Patients With Pierre Robin Sequence: Operative Considerations
In cleft surgery there is no current general agreement on the treatment strategy of patients with the Pierre Robin Sequence. The timing of surgery and the surgical approach depends on the treating physician or the hospital…
- Trial name
- NCT02658318
- Where
- Belgium
- Volunteers
- 92 people
- Sponsor
- AZ Sint-Jan AV
Osteoarthritis
Intensive Diet and Exercise for Improving Knee Osteoarthritis in Obese and Overweight Older Adults
The purpose of this study is to compare the effects of a calorie-restricting diet, exercise, and a combination of both in reducing knee inflammation and compressive forces in obese and overweight adults with knee osteoarthritis…
- Trial name
- NCT00381290
- Testing
- Diet, Exercise
- Where
- United States
- Volunteers
- 454 people
- Sponsor
- Wake Forest University
Knee Osteoarthritis, Osteoarthritis, Knee
Autologous Conditioned Serum: Functional and Clinical Results
The purpose of this study was to investigate the potential ability of autologous conditioned serum (ACS) to decrease the pain and improve the joint functionality in patients affected by knee osteoarthritis (OA).
- Conditions
- Knee Osteoarthritis, Osteoarthritis, Knee, Cartilage Degeneration
- Trial name
- NCT03850080
- Testing
- Autologous Conditioned Serum
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- Ospedale San Raffaele
Hyperalgesia, Healthy Subjects
Spread of Muscle Hyperalgesia and Pain in a Low Dose NGF-induced Pain Model
The purpose of this study is to investigate and determine the time course and distribution on muscle hyperalgesia and muscle pain in a repeated, low dose NGF model.
- Trial name
- NCT03217942
- Testing
- NGF
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Ultrasound, Botulinum Toxin
Ultrasound-Guided Versus Anatomically Guided Botulinum Toxin Injection in Spasticity in Adults in Tanta University Hospitals
This study aimed to compare the safety and outcome of ultrasound (US)- guided botulinum toxin (BoNT) injection and anatomically guided injection in muscle spasticity of different causes in adults.
- Conditions
- Ultrasound, Botulinum Toxin, Spasticity, Adults
- Trial name
- NCT06941883
- Testing
- Botulinum toxin injection under anatomical landmark, Ultrasound-guided botulinum toxin injection
- Where
- Egypt
- Volunteers
- 68 people
- Sponsor
- Tanta University
Trigger Point Pain, Myofascial, Neck Pain
Effects of Myofascial Releasing on Neck Pain in Patients With Trigger Points
Aim of this study is to investigate effectiveness of myofascial releasing on neck pain related to trigger points located on upper cervical region.
- Trial name
- NCT03585283
- Testing
- Myofascial Group
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Abant Izzet Baysal University
Shoulder Fractures, Shoulder Arthritis Osteoarthritis
Zimmer Biomet Shoulder Arthroplasty PMCF Study
This is a multicenter, prospective, non-controlled post market surveillance study. The objectives of this study are to confirm the safety, performance, and clinical benefits of the Zimmer Biomet Shoulder Arthroplasty systems in…
- Conditions
- Shoulder Fractures, Shoulder Arthritis Osteoarthritis, Shoulder Injury, Shoulder Pain
- Trial name
- NCT06920459
- Testing
- Alliance™ Glenoid
- Where
- 2 sites in Germany, Netherlands
- Volunteers
- 50 people
- Sponsor
- Zimmer Biomet
Spondyloarthritis
Treatment of Axial Spondyloarthritis by Recombinant Human Tumor Necrosis Factor-α Receptor Ⅱ IgG Fc Fusion Protein
This is a randomized, double-blind, multicentral clinical trial to investigate the efficacy and safety of Recombinant Human Tumor Necrosis Factor-α Receptor Ⅱ IgG Fc fusion protein injection (Yisaipu®) in the treatment of active…
- Trial name
- NCT02364479
- Testing
- 50mg Yisaipu, 25mg etanercept
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Sun Yat-sen University
Musculoskeletal Disorders, Musculoskeletal Pain
The Efficacy of Ergonomic Intervention in Preventing Musculoskeletal Disorders Among Women After Giving Birth
The woman's body undergoes many physiological changes during pregnancy, which can cause muscle weakness and postpartum joint instability.
- Conditions
- Musculoskeletal Disorders, Musculoskeletal Pain, Post Partum
- Trial name
- NCT04244279
- Testing
- Ergonomic workshop, Brochure, Videos
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Burnout Syndrome
Evaluating the Impact of Mindfulness Based Physical Therapy on Burnout Syndrome Among University Students.
The goal of this clinical trial is to evaluate whether a mindfulness-based physical therapy intervention can reduce burnout syndrome and improve musculoskeletal pain and quality of life among undergraduate Allied Health Sciences…
- Trial name
- NCT07456527
- Testing
- Standard Physical Therapy, Mindfulness Based Physical Therapy
- Where
- Pakistan
- Volunteers
- 55 people
- Sponsor
- University of Health Sciences Lahore
Musculoskeletal Pain, Cognitive Change
Health, Wellbeing and Performance in Law Enforcement Workers
This study aims to assess current health and fitness of law enforcement workers in various roles, and to evaluate the impact of an exercise intervention on markers on physical and mental wellbeing in this population.
- Conditions
- Musculoskeletal Pain, Cognitive Change, Occupational Stress, Inflammation
- Trial name
- NCT04204486
- Testing
- Exercise
- Where
- United Kingdom
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University College, London
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