Clinical trials: Musculoskeletal Symptom
Lumbar Herniated Intervertebral Disc
The Efficacy and Safety of the 1,414 nm Nd:YAG Laser System for Alleviating Back Pain in a Lumbar Disc Patient
This study aims to evaluate the efficacy and safety of the 1,414nm Nd:YAG laser system (ACCUPLASTI) added to Percutaneous Epidural Neuroplasty (PEN), a conventional treatment, to alleviate back pain in a lumbar herniated…
- Trial name
- NCT02598232
- Testing
- 1,414nm Nd:YAG Laser System
- Volunteers
- 30 people
- Sponsor
- CynosureLutronic
Fibromyalgia Syndrome, Fibromyalgia
Can a Relaxometer Improve Cognitive Impairment of Fibromyalgia Patients
The aim of the study is to evaluate the differences in cognitive performance and quality of life, after a cycle of treatment with the relaxometer, between a group of patients affected by fibromyalgia and a control group.
- Conditions
- Fibromyalgia Syndrome, Fibromyalgia, Pain, Chronic, Impairment
- Trial name
- Fibrorilax (NCT04170387)
- Testing
- Relaxometer
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Shoulder Pain, Shoulder Injuries
Efficacy of a Criteria Based Clinical Pathway for Rehabilitation of Shoulder Injuries
The goal of this clinical trial is to compare the current standard of care for rehabilitation of non-operative shoulder injuries to a novel, criteria-based approach (CRISP).
- Trial name
- CRISP (NCT06536114)
- Testing
- CRISP: Criteria-Based Approach for the Rehabilitation for Non-Operative Shoulder Injuries, Standard of Care
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- United States Naval Medical Center, San Diego
Musculoskeletal Abnormalities, Obesity
GLP-1R Actions on Muscle and the Skeleton
The GRAMS study objectives are to assess the musculoskeletal changes that occur after weight loss using GLP-1 based therapy. A lifestyle intervention with diet and exercise is included to assess any mitigating effects are…
- Conditions
- Musculoskeletal Abnormalities, Obesity, Sarcopenic Obesity, Osteoporosis
- Trial name
- GRAMS (NCT07154719)
- Testing
- Tirzepatide, Lifestyle toolkit
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Pennington Biomedical Research Center
Tendinopathy
Efficacy of Therapeutic Percutaneous Electrolysis Simple vs Multiple vs Laser Therapy in Supraspinatus Tendinopathy.
Supraspinatus tendinopathy is one of the main pathologies that cause functional alterations in the glenohumeral joint. It reduces the quality of life of the population suffering from this injury.
- Trial name
- NCT07695792
- Testing
- Simple electrolysis percutaneous, Multifiliar Electrolysis percutaneus, Laser
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Universidad Pontificia de Salamanca
Pain Management, Fibromyalgia
Effects of Adding Motor Imagery Training to Exercise on Pain, Fibromyalgia Impact, and Kinesiophobia in Women With Fibromyalgia: a Randomized Controlled Trial
Aim: To evaluate the effects of adding motor imagery training to exercise on pain, fibromyalgia impact, and kinesiophobia in women with fibromyalgia, and compare imagery ability and kinesiophobia with healthy volunteers.
- Conditions
- Pain Management, Fibromyalgia, Imagery, Psychotherapy
- Trial name
- NCT07883434
- Testing
- Motor imagery
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ufuk University
Hemiplegia, Muscle Spasticity
Tele-physiotherapy on Post-stroke Hemiplegia Patients
The present preliminary randomized trial will be performed to compare the effectiveness of telephyisiotherapy plus physical exercises versus other conventional techniques (electromyographic biofeedback or conventional…
- Trial name
- NCT06048432
- Testing
- Conventional Physiotherapy + telephysiotherapty
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad Católica San Antonio de Murcia
Musculoskeletal Diseases, Musculoskeletal Injury
Prevalence of Musculoskeletal Symptoms in the Cambridge NIHR BioResource
Musculoskeletal diseases, such as osteoarthritis, represent a large proportion of the global burden of disease with hip and knee osteoarthritis alone being the 11th greatest cause of disease burden.
- Trial name
- NCT04632563
- Testing
- Questionnaire including MSK-HQ (Musculoskeletal Health Questionnaire)
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Pain, Virtual Reality
Neural Mechanisms of Immersive Virtual Reality in Chronic Pain
This project examines, in chronic pain, the mechanisms of immersive virtual reality compared to the mechanisms of placebo hypoalgesia.
- Conditions
- Pain, Virtual Reality, Placebo, Temporomandibular Disorder
- Trial name
- NCT04851301
- Testing
- Active Virtual Reality, No Intervention, Naloxone
- Where
- United States
- Volunteers
- 259 people
- Sponsor
- University of Maryland, Baltimore
Inflammation; Muscle, Iron Metabolism
The Effect of Supplementation of Vitamin D3 on Inflammation Induced by 100 km Running, Iron Metabolism and Erythropoiesis
A group of runners received vitamin D (10,000 IU - international unit per day) for two weeks. The aim of the intervention was to check the effect of vitamin D supplementation on selected parameters of inflammation and iron…
- Conditions
- Inflammation; Muscle, Iron Metabolism, Ineffective Erythropoiesis, Healthy
- Trial name
- NCT05880030
- Testing
- Cholecalciferol
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Gdansk University of Physical Education and Sport
Frail Elderly, Muscle Weakness
Translating 3-Step Workout for Life in a Local Senior Living Community
The study evaluates the feasibility of a staff-lead workout program, 3-Step Workout for Life, in a local senior living community. Eligible participants will complete assessments before and after the workout program.
- Trial name
- NCT03095534
- Testing
- 3-Step Workout for Life
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Indiana University
Trigger Point Pain, Myofascial, Muscle Pain
Dry Needling Versus Intramuscular Stimulation in the Management of the Myofascial Trigger Points
Hypothesis The application of intramuscular electrostimulation will be more effectiveness than the dry needling in myofascial trigger points treatment.
- Conditions
- Trigger Point Pain, Myofascial, Muscle Pain, Myofascial Pain Syndrome
- Trial name
- NCT03025230
- Testing
- Dry needling and electric stimulation, Dry needling
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- University of Alcala
Stroke
Subacromial Space in Chronic Stroke Patients
This study aims to examine the subacromial space, shoulder pain, and shoulder disability in chronic stroke patients. A total of 60 chronic stroke patients aged 40-65 with similar demographic characteristics are planned to be…
- Trial name
- NCT07139665
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Ankara University
Fibromyalgia (FM), Chronic Low Back Pain (CLBP)
Pain Neuroscience Education for Chronic Pain
Chronic pain is an unpleasant sensory and emotional experience associated with actual or potential tissue damage, with a high prevalence in Spain (25.9%) and an average duration of 6.83 years, highlighting its significant health…
- Conditions
- Fibromyalgia (FM), Chronic Low Back Pain (CLBP), Chronic Pain
- Trial name
- PNE (NCT07693998)
- Testing
- Therapeutic Exercise and Education in Pain Neuroscience
- Where
- Spain
- Volunteers
- 84 people
- Sponsor
- University of Valencia
Periodontal Diseases, Biomarkers
Impact of Periodontal Treatment on the RANKL/OPG Ratio in Crevicular Fluid
Objectives: Alveolar resorption is one of the most important events in periodontitis. Osteoclast activity is regulated by the ratio between receptor activator of NF-κB ligand (RANKL) and osteoprotegerin (OPG).
- Conditions
- Periodontal Diseases, Biomarkers, Bone Resorption
- Trial name
- NCT03787875
- Testing
- periodontal treatment
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Postoperative Pain, Myalgia
Effects of Preemptive Paracetamol and Ibuprofen on Headache and Myalgia in Patients After Electroconvulsive Therapy
The primary aim this prospective, randomized, double-blind, placebo-controlled clinical trial is to compare the analgesic effects of preemptive intravenous paracetamol and ibuprofen on headache and myalgia, and secondary aim is…
- Conditions
- Postoperative Pain, Myalgia, Headache
- Trial name
- ECT (NCT03783312)
- Testing
- paracetamol, ibuprofen
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Inonu University
Mobility Limitation, Frailty
Assisted Ambulation to Improve Health Outcomes for Older Medical Inpatients
The investigator proposes to conduct a randomized trial of supervised ambulation delivered by mobility technician (MT) up to three times daily, including weekends, to hospitalized medical patients.
- Conditions
- Mobility Limitation, Frailty, Hospital Acquired Condition, Weakness, Muscle
- Trial name
- NCT05725928
- Testing
- Mobility technician
- Where
- 5 sites in United States
- Volunteers
- 3,000 people
- Sponsor
- The Cleveland Clinic
Bisphosphonate Related Osteonecrosis of the Jaws (BRONJ), Oxygen
Topical Oxygen Therapy for BRONJ
A randomized clinical trial comparing Blue®m oral gel and autologous PRF membrane as adjuncts to surgical debridement in BRONJ/MRONJ patients.
- Conditions
- Bisphosphonate Related Osteonecrosis of the Jaws (BRONJ), Oxygen, Topical Administration, Wound Healing
- Trial name
- OXY-BRONJ Tria (NCT07725107)
- Testing
- Topical Blue®m application, PRF membrane placement
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Mansoura University
Prader-Willi Syndrome, PWS-like Syndrome
GROWing Up With Rare GENEtic Syndromes
Introduction Rare complex syndromes Patients with complex genetic syndromes, by definition, have combined medical problems affecting multiple organ systems, and intellectual disability is often part of the syndrome.
- Conditions
- Prader-Willi Syndrome, PWS-like Syndrome, Silver Russel Syndrome, Congenital Hypopituitarism
- Trial name
- GROW UR GENES (NCT04463316)
- Testing
- Retrospective file studies
- Where
- Netherlands
- Volunteers
- 600 people
- Sponsor
- dr. Laura C. G. de Graaff-Herder
Gout, Hyperuricemia
A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ABP-671 in Healthy Subjects
The purpose of this study is to assess the safety, tolerability, pharmacokinetics and pharmacodynamics of single ascending doses of ABP-671 administered orally in healthy volunteers.
- Trial name
- NCT03906006
- Testing
- ABP-671
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Atom Therapeutics Co., Ltd
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