Clinical trials: Musculoskeletal System
Acromegaly, Pituitary Tumor
The Observational Study of Growth Hormone-secreting Pituitary Tumors
The major purpose of this study is to evaluate the changes of multiple organs in patients with growth hormone-secreting pituitary tumors before and after surgery.
- Trial name
- NCT01368133
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Huashan Hospital
Spondyloarthritis, Ruminococcus Gnavus
The Role of Intestinal Microbiota Dysbiosis in the Development of Spondyloarthritis
The primary objective of this case-control study aims to explore the role of bacterium Ruminococcus gnavus (R. gnavus) with intestinal biopsy and faecal sampling in the initiation and the development of spondyloarthritis (SPA) in…
- Trial name
- RUMINOSPA (NCT04853212)
- Testing
- Biopsy
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Bone Loss
Release Kinetics of rhBMP-2 Using E-PRF as an Autologous Carrier: An In Vitro Analysis
This study is seeking to evaluate the binding of a commercially-available, recombinant human osteoinductive growth factor, rhBMP-2, to a human blood derived product scaffold, enhanced Platelet-rich fibrin (E-PRF), and the release…
- Trial name
- NCT04670965
- Testing
- E-PRF/rhBMP-2 (similar ratios), E-PRF/ACS/rhBMP-2, rhBMP-2/E-PRF
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Degenerative Disc Disease, Disc Herniation
Adjacent Level Anterior Cervical Fusion: SeaSpine Shoreline Versus Removal of Previously Implanted Plate and Replating
The purpose of this study is to evaluate the efficacy of SeaSpine Shoreline device in surgery of the cervical spine.
- Trial name
- NCT06415136
- Testing
- SeaSpine Shoreline
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Research Source
Osteoporosis
Bindex Ultrasonometer for Osteoporosis Diagnostics
Osteoporosis is a disease that leads to impaired skeletal strength and increased fracture risk. Among 200 million osteoporotic patients (Tarantino, Cannata et al. 2007) most are diagnosed only after a fracture.
- Trial name
- NCT01935232
- Where
- United States
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Bone Index Finland Ltd
Injury;Sports, Muscle Soreness
Effects of Percussion Therapy on the Biomechanics of Pickleball Movement
With increased demand on pickleball as a recreational exercise, it is of interest in investigating the biomechanical characteristics of pickleball and determining the impacts of percussion therapy on them.
- Trial name
- NCT07005934
- Testing
- Theragun Prime
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Point Loma Nazarene University
Bandages, Muscle Soreness
Kinesio Taping in Muscle Damage Response Induced by Eccentric Exercise
Sixty volunteers with a mean age of 21,8 ± 2,6 years participated in this study, randomly distributed into one of the following groups: control, Kinesio taping group with tension in the anterior arm region and Kinesio taping…
- Trial name
- NCT02945098
- Testing
- Kinesio Taping
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio Grande do Norte
Growth Hormone Deficiency
Growth Hormone's Effect on the Cardiovascular System
To evaluate specific markers of cardiovascular risk before and after growth hormone replacement therapy in a population of growth hormone deficient adults, as compared to an age, gender, and BMI-matched healthy population.
- Trial name
- NCT00397319
- Testing
- Growth Hormone
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Patellar Dislocation
Comparison of Two Graft Choices in Mediale Patellofemoral Ligament Reconstruction (MPFL)
The purpose of this study is to elucidate surgical techniques for reconstructing MPFL in the treatment of chronic patella instability.
- Trial name
- NCT05706363
- Testing
- Quadriceps graft
- Where
- Denmark
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Bone Density Increased
Radiographic Assessment of Bone Dimension Around Immediate Implants With FDBA and I-PRF vs FDBA Alone
The present study is a human, prospective, parallel, randomised controlled clinical trial conducted for radiographic assessment of bone dimension around immediate implants with FDBA and I-PRF vs FDBA Alone The trial is in…
- Trial name
- NCT06522321
- Testing
- i-PRF and FDBA
- Where
- India
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
Dental Implant, Dental Implant-Abutment Design
RCT Comparing KS Versus TS for Ovedenture
To evaluate the clinical and radiographic outcomes of KS implants used to rehabilitate edentulous mandible with dental-retained overdentures, and to compare it with same treatment on TS implants
- Conditions
- Dental Implant, Dental Implant-Abutment Design, Edentulous Jaw
- Trial name
- NCT06276712
- Testing
- Implant placement with 3.5 mm diameter KS implants., Implant placement with 3.5 mm diameter TS implants.
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Università degli Studi di Sassari
Facioscapulohumeral Muscular Dystrophy
Effectiveness of Upper Extremity Rehabilitation in pwFSHD (Patient With Facioscapulohumeral Dystrophia)
Facioscapulohumeral Muscular Dystrophy (FSHD) is one of the most common forms of muscular dystrophy, characterized by pronounced skeletal weakness and with a broad spectrum of diseases.
- Trial name
- NCT05178706
- Testing
- upper extremity rehabilitation program, Results of assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Tennis Elbow
Manual Therapy on Lateral Elbow Pain
This randomised, controlled, double-blind experimental study is designed to evaluate the efficacy of a standardised manual physiotherapy protocol for treating lateral epicondylalgia of the humerus, commonly known as 'tennis…
- Trial name
- NCT07461311
- Testing
- Manual Therapy
- Where
- Spain
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of La Laguna
Genu Varum, Football Players
The Influence of the Lower Limb Components on Genu Varum in Football Players
Objectives: To evaluate lower extremity alignments in football players with and without genu varum using magnetic resonance imaging (MRI), to determine the mechanisms underlying malalignment and the factors contributing to it.
- Trial name
- NCT06606964
- Testing
- Magnetic Resonance Imaging, Isokinetic Strength
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Tuba Melekoğlu
Obesity, Overweight
Abdominal and Core Exercises on Respiratory Functions in Obese and Overweight Women (COREBREATH)
This study aims to examine the effects of an 8-week Pilates-based exercise program on breathing functions in overweight and obese women (BMI ≥ 25).
- Conditions
- Obesity, Overweight, Pulmonary Disease, Muscle Weakness
- Trial name
- COREBREATH (NCT07103499)
- Testing
- Pilates-Based Core and Breathing Exercise Program
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Flexible Flatfoot
High-Intensity Focused Electromagnetic Therapy Combined With Foot Core Training for Pronated Foot
The objective of this trial is to assess the effects of high-intensity focused electromagnetic therapy combined with foot core training targeting the intrinsic foot muscles on plantar load, static foot posture, intrinsic foot…
- Trial name
- NCT06401954
- Testing
- High-intensity focused electromagnetic therapy, Foot core training
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Anterior Cruciate Ligament Reconstruction, Tranexamic Acid
Tranexamic Acid Injection With Different Drainage Clamping Time After Anterior Cruciate Ligament Reconstruction
Post-anterior cruciate ligament reconstruction (ACLR) hemarthrosis may result in increased pain thus delaying postoperative rehabilitation, which may eventually lead to arthrofibrosis and a functional deficit.
- Conditions
- Anterior Cruciate Ligament Reconstruction, Tranexamic Acid, Hemarthrosis, Knee
- Trial name
- NCT06280456
- Testing
- Tranexamic Acid Powder
- Where
- Taiwan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Inflammatory Disease, Crohn Disease
Monitoring of Inflammatory Conditions
People with inflammatory diseases treated with immune-suppressing medication are recommended to have regular blood-tests to monitor for potential side-effects of this treatment on their blood count, liver and kidneys.
- Conditions
- Inflammatory Disease, Crohn Disease, Ulcerative Colitis, Rheumatoid Arthritis
- Trial name
- NCT05458531
- Testing
- Questionnaire, Semi-structured interview
- Where
- United Kingdom
- Volunteers
- 664 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Diastasis, Muscle
Effect of Four Exercises on the Inter-recti Distance in Women
Diastasis rectus abdominis (DRA) is defined as an excessive separation between the two abdominal rectus muscles. It is generally quantified by the inter-recti distance.
- Trial name
- Traecho (NCT04501302)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- APOR B de Gasquet
Osteoporosis
Assess Bioequivalence of One 150 mg Risedronate Tablet Versus Two 75 mg Risedronate Tablets in Healthy Subjects
This study is a randomized, open-label, crossover study to assess the bioequivalence of 1 risedronate 150 mg tablet versus 2 risedronate 75 mg tablets administered as a single oral dose.
- Trial name
- NCT00699777
- Testing
- Risedronate
- Where
- 4 sites in United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Warner Chilcott
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