Clinical trials: Musculoskeletal System
Lumbar Disc Herniation
A Biomechanical Study of the Lumbar Intervertebral Disc by Lever Positioning Manipulation
Purpose of Study: The purpose of this clinical trial is the clinical efficacy of different trigger modes of lever positioning manipulation (LPM) for the treatment of lumbar disc herniation (LDH).
- Trial name
- NCT06872918
- Testing
- Lever positioning manipulation, Cluster of pseudo-manipulators, Mechanics and kinematics data acquisition of unilateral wrenching patterns in lever positioning manipulation
- Where
- China
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- The Third Affiliated hospital of Zhejiang Chinese Medical University
Shoulder Pain
A Comparative Study Between Anterior Glenoid Block With Sub-omohyoid Suprascapular Block Versus Interscalene Block in Shoulder Arthroscopy
The patients will be randomized into 2 equal groups by a computer-generated random numbers table, named group A, B. Group A: Patients will receive Anterior glenoid block combined with suprascapular nerve block.
- Trial name
- NCT06609590
- Testing
- Glenoid nerve block combined with Sub-omohyoid Anterior Suprascapular nerve Block, Interscalene brachial plexus block
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Dry Eye, Sjogren's Disease
Multi-Colored Placido Disk Viability
The purpose of this study is to show that the multi-colored Placido Disk set-up can get reliable data over long time periods.
- Conditions
- Dry Eye, Sjogren's Disease, Healthy
- Trial name
- NCT02148497
- Testing
- Multi-colored Placido disk imaging
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Femoroacetabular Impingement
Regional Anesthesia in Hip Arthroscopy
The purpose of this research is to determine differences in outcomes in patients who receive regional anesthesia (a fascia iliaca block) versus placebo prior to undergoing hip arthroscopy with labral repair and/or debridement and…
- Trial name
- NCT02674113
- Testing
- regional anesthesia bupivacaine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Adhesive Capsulitis
Spencer's Muscle Energy Technique Along With Strain Counter Strain in Adhesive Capsulitis.
Numerous Physiotherapy techniques have been found to be beneficial but there is no consensus on the best treatment approach for speeding up rehabilitation process and rejuvenating functional capacity in patients suffering from…
- Trial name
- NCT04822324
- Testing
- Spencer Muscle energy technique with conventional Physiotherapy, Strain counter strain along with conventional Physiotherapy and Spencer Muscle energy technique
- Where
- Pakistan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Spinal Cord Injury, Spasticity, Muscle
Identification of Sodium Channel Fragments as Serum Biomarkers of a Traumatic Central Nervous System Injury
Following spinal cord injury (SCI), 75% of patients develop spasticity of the limbs characterized by an increase in muscle tone causing severe pain.
- Conditions
- Spinal Cord Injury, Spasticity, Muscle, Brain Injuries
- Trial name
- SpasT-SCI-T (NCT06532760)
- Testing
- Blood sampling
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assistance Publique Hopitaux De Marseille
Shoulder Pain
3D Shoulder Kinematics During Throwing-related Movement Patterns Tasks in Upper Extremity Low-to-moderate/Moderate-to-high Loading Conditions
The main purpose of this study is to characterize and compare the 3D shoulder kinematics bilaterally while performing functional movement patterns tests that hypothetically replicate the 5 main phases of the throwing cycle.
- Trial name
- NCT02852785
- Testing
- PNF D2 for flexion; low-to-moderate loading condition, PNF D2 for flexion; moderate-to-high loading condition, PNF D2 for extension; low-to-moderate loading condition
- Where
- 3 sites in Portugal
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Chronic Migraine, Fibromyalgia
Study of Low-dose Naltrexone in Chronic Migraine With Fibromyalgia
This research aims to look at the effect of low-dose naltrexone on the severity and frequency of attacks in people with chronic migraine with or without new daily persistent headache and fibromyalgia.
- Conditions
- Chronic Migraine, Fibromyalgia, New Daily Persistent Headache
- Trial name
- NCT05536050
- Testing
- Migraine diary and Questionnaires
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Cumulative Trauma Disorders
Musculoskeletal Injuries' Prediction Tool for Military Combatants in the Israeli Defense Force
Emerging evidences indicate that performance on a variety of functional movement screens can identify athletes/soldiers at risk for injury.
- Trial name
- FMS (NCT02091713)
- Testing
- Functional movement screen
- Where
- Israel
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Hypercholesterolemia, Osteoporosis
Food Matrix and Genetic Variability as Determinants of Bioavailability and Biological Effects of Beta-cryptoxanthin and Phytosterols
Regular consumption of a beverage containing β-cryptoxanthin (b-Cx) and plant sterols (Ps) has been shown to exert a synergic effect in reducing cardiovascular risk and bone remodeling markers (formation and resorption).
- Trial name
- foodmagenpol (NCT02065024)
- Testing
- b-cryptoxanthin plus phytosterols
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Puerta de Hierro University Hospital
Temporomandibular Joint Disorders, Rheumatoid Arthritis
Temporomandibular Joint in Patients With Rheumatoid Arthritis
the investigators study aimed to evaluate temporomandibular joint involvement in rheumatoid arthritis patients and healthy individuals 142 participants were recruited in two groups: 72 patients with Rheumatoid Arthritis (RA), and…
- Trial name
- NCT06134726
- Testing
- seropositivity of rheumatoid factor
- Where
- Syria
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Syrian Private University
Mandible Small
Augmentation of Atrophic Mandibule Using Poly Ether Ether Ketone Mesh
Comparative study between custom-made polyether ether ketone and titanium mesh for augmentation of atrophic posterior mandible.
- Trial name
- RCT (NCT04017117)
- Testing
- under local anasthesia,Ridge Augmention of posterior atrophic mandible by using mix of autogenous bone graft and bone substitutes is used under PEEK mesh
- Where
- Egypt
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Cairo University
PARKINSON DISEASE (Disorder), Rigidity
Spinal Mobility, Rigidity, and Kinesiophobia in PD and TMD
Axial rigidity and loss of spinal mobility commonly observed in Parkinson's disease (PD) lead to postural deformities and substantial reductions in trunk flexibility.
- Conditions
- PARKINSON DISEASE (Disorder), Rigidity, Temporomandibular Disorders (TMDs), Mobility
- Trial name
- NCT07850674
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mustafa Kemal University
Lymphoma, Salivary Gland Disease
Natural History of Salivary Gland Dysfunction and Sjogren's Syndrome
This study will follow patients with salivary gland dysfunction to identify the long-term course of this disorder and its effects on the mouth, oral function, and overall health.
- Conditions
- Lymphoma, Salivary Gland Disease, Sjogren's Syndrome, Xerostomia
- Trial name
- NCT00001852
- Where
- United States
- Volunteers
- 560 people, healthy volunteers welcome
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Orthopedic Disorder
Comparison of Remimazolam and Dexmedetomidine for Intraoperative Sedation
The purpose of this study is to compare the sedation efficacy of dexmedetomidine and remimazolam for intraoperative sedation during regional block.
- Trial name
- NCT05447507
- Testing
- Remimazolam, Dexmedetomidine
- Where
- South Korea
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Scoliosis, Scoliosis Idiopathic
Investigation of the Effects of Exercise and Kinesiological Taping on Spinal Deformities and Serum Markers in Individuals With Scoliosis
The aim of this study is to investigate the effects of Schroth exercises and kinesiological taping on spinal deformities and serum markers in young adults with scoliosis.
- Conditions
- Scoliosis, Scoliosis Idiopathic, Musculoskeletal Deformity
- Trial name
- NCT06341465
- Testing
- Just Exercise, Exercise, Taping
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Periodontal Disease
Effect of Actonel on Periodontal Health of Postmenopausal Women
Hypothesis: Women who use Actonel (risedronate) for osteopenia will show beneficial periodontal effects.
- Trial name
- NCT00594334
- Testing
- Risedronate
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Menopause, Fracture
Forteo for the Treatment of Unexplained Osteoporosis in Premenopausal Women
Idiopathic osteoporosis (IOP) is an uncommon disorder in which otherwise healthy young individuals sustain one or more low-trauma fractures.
- Conditions
- Menopause, Fracture, Osteoporosis
- Trial name
- IOPForteo (NCT00697463)
- Testing
- Teriparatide (PTH 1-34)
- Where
- 2 sites in United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Columbia University
Osteoporosis
Osteoporosis and Dental Implant
The purpose of this study is to evaluate the influence of alendronate therapy on the wound healing after dental implants in patients with osteoporosis.
- Trial name
- OPOZAHN (NCT00727493)
- Testing
- alendronate once weekly 70mg
- Where
- Germany
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Acromegaly
Reproducibility and Utility of OGTT in Acromegaly
Prospective study of reproducibility and utility of growth hormone inhibition by oral glucose tolerance test for the diagnosis of acromegaly, in acromegalic and non-acromegalic subjects, with a randomized double-blind crossover…
- Trial name
- ACROTEST (NCT04066569)
- Testing
- Performed 2 diagnostic tests (2 OGTT tests with 75g of Glucose)
- Where
- France
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
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