Clinical trials: Myalgia
HMG-CoA Reductase Inhibitors-related Myalgias
Vitamin D Replacement: The Effect on Statin-Related Myalgias
The purpose of this project is to determine if Vitamin D supplementation [10,000 international units of cholecalciferol (vitamin D3) by mouth weekly] will decrease the rate of discontinuation of statin therapy due to muscle…
- Trial name
- NCT01022398
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Creighton University
Osteoarthritis, Rheumatoid Arthritis
Efficacy and Safety of Buprenorphine Transdermal Patch in Non-cancer Pain of Moderate Intensity
This is a phase IV, open-label and single-arm study of patients with non-malignant pain due to osteoarthritis, rheumatoid arthritis, low back pain and joint/muscle pain, who were not responding to non-opioid analgesics.
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Lower Back Pain, Joint Pain
- Trial name
- NCT02519387
- Testing
- Buprenorphine Transdermal Patch
- Where
- 3 sites in Malaysia
- Volunteers
- 78 people
- Sponsor
- Mundipharma Pharmaceuticals Sdn. Bhd.
Pain, Postoperative, Anesthesia, Local
Postoperative Pain Relief With Transversus Thoracis Muscle Plane Block After Cardiac Surgery
This study aims to investigate the effect of transversus thoracis muscle plane block (TTP), using repeated boluses of ropivacaine via catheter, on postoperative pain and oxycodone consumption after elective cardiac surgery with…
- Conditions
- Pain, Postoperative, Anesthesia, Local, Coronary Artery Disease, Heart Valve Diseases
- Trial name
- TTPcat (NCT04916418)
- Testing
- Ropivacaine
- Where
- Finland
- Volunteers
- 120 people
- Sponsor
- Turku University Hospital
Osteoarthritis, Rheumatoid Arthritis
Evaluation Of Efficacy And Safety Of Norspan In Moderate To Severe Pain Due To Osteoarthritis, Rheumatoid Arthritis, Joint/Muscle Pain
The purpose of this study is to assess the efficacy of the buprenorphine transdermal patch (Norspan® or Sovenor® transdermal patch) in patients with chronic non-malignant pain of moderate to severe intensity due to…
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Lower Back Pain, Joint Pain
- Trial name
- NCT01961271
- Testing
- Buprenorphine transdermal patch
- Where
- 16 sites in Hong Kong, Philippines and 1 more
- Volunteers
- 114 people
- Sponsor
- Mundipharma Pte Ltd.
Pelvic Floor Dyssynergia
Baclofen/Diazepam Supps for Treatment of Pelvic Floor Myalgia
This study is a randomized, placebo controlled double blind cross over trial. Patients presenting with pelvic floor myalgia will be asked to complete a series of standardized questionnaires to assess their pain, quality of life…
- Trial name
- BDS (NCT03427216)
- Testing
- Baclofen/diazepam
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dr. John A. Thiel Medical Professional Corporation
Muscle Pain, Feedback, Psychological
Evaluation of Biofeedback Therapy Efficiency in Masticatory Muscles Pain Management
This study evaluates beneficial effects of biofeedback therapy in reducing pain and increased tension of muscles occurring in patients with temporomandibular disorders (TMD).
- Conditions
- Muscle Pain, Feedback, Psychological, Craniomandibular Disorders, Temporomandibular Disorder
- Trial name
- NCT03421028
- Testing
- Electromyography Biofeedback, Classic treatment for myogenous TMD
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Wroclaw Medical University
Acute Muscle Pain
Evaluation of Efficacy and Safety of SPARC1401 in Acute Low Back Pain
A phase 2 randomized clinical trial to evaluate efficacy and safety of SPARC1401 at three dose levels in patients with acute low back pain
- Trial name
- NCT02887534
- Testing
- SPARC1401-low dose, SPARC1401-mid dose, SPARC1401-high dose
- Sponsor
- Sun Pharma Advanced Research Company Limited
Fibromyalgia, Primary, Pain
Bio-significance of LPC16:0 in Fibromyalgia
Fibromyalgia (FM) is a very common but mysterious pain disorder characterized by chronic widespread muscular pain. Fatigue, anxiety and depression are common comorbidities.
- Conditions
- Fibromyalgia, Primary, Pain, Soreness, Muscle, Oxidative Stress
- Trial name
- NCT04832100
- Testing
- Pregabalin 150mg, imipramine 25mg
- Where
- Taiwan
- Volunteers
- 245 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
SARS-CoV-2 Acute Respiratory Disease, Myalgic Encephalomyelitis
Does a Technology Enabled Multi-disciplinary Team-based Care Model for the Management of Long COVID and Other Fatiguing Illnesses Improve Clinical Care of Patients and Represent a Sustainable Approach Within a Federally Qualified Health Center?
The primary objective of the present research is to determine the effectiveness of Family Health Center of San Diego's Long COVID and Fatiguing Illness Recovery Program (LC\&FIRP) on clinician- and patient-level outcomes.
- Conditions
- SARS-CoV-2 Acute Respiratory Disease, Myalgic Encephalomyelitis, Chronic Fatigue Syndrome, Post-acute Sequelae of SARS-COV-2 Infection
- Trial name
- LC&FIRP (NCT05167227)
- Testing
- Extension for Community Healthcare Outcomes
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Family Health Centers of San Diego
Temporomandibular Dysfunction (TMD)
Cervical Proprioception, Masticatory Pain Threshold and Craniovertebral Angle in TMD
Temporomandibular disorder (TMD) is a group of conditions involving the masticatory muscles, temporomandibular joint (TMJ), and associated structures of the head, neck, and cervical region.
- Trial name
- NCT07681570
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Delayed Onset Muscle Soreness Experimentally Induced
Clinical and MRI Characteristics of Delayed Onset Muscle Soreness (DOMS) of the Shoulder Rotator Muscles Induced by Eccentric Exercise: An Exploratory Prospective Experimental Study
The purpose of this study is to characterize the clinical and radiological manifestations of delayed onset muscle soreness (DOMS) experimentally induced by an isokinetic eccentric contraction protocol targeting the shoulder…
- Trial name
- DOMEX (NCT07880782)
- Testing
- Isokinetic dynamometer
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Headache Disorders, Headache
Effectiveness of a Cognitive and Physical Intervention to Reduce Head and Muscle Pain in Working Communities
The primary purpose of this study is to evaluate the effectiveness of a workplace cognitive and physical program (Intervention), in reducing the frequency of head and neck pain
- Conditions
- Headache Disorders, Headache, Neck Pain, Shoulder Pain
- Trial name
- NCT00457496
- Testing
- Cognitive, behavioral, exercise
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Turin, Italy
Myofacial Pain
Prospective, Cross Over Gabapentin vs Amitriptyline Study on Patients Suffering From Masticatory Muscle Pain
The purpose of the study is comparing two drugs efficacy for the treatment of pain originates from masticatory muscles. The two drugs are - Amitriptlyne (amitriptyline) and Gabapentin (gabapentin), both of them are common use in…
- Trial name
- NCT02339662
- Testing
- Gabapentin, Amitriptyline
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Doron Aframian
Pain, Acute
Controlled Study to Assess the Efficacy and Safety of S-Ibuprofen Topical Gel 5% (AP0302) in the Treatment of DOMS
Phase 2 study designed to evaluated analgesic efficacy and safety of S-Ibuprofen Topical Gel 5%
- Trial name
- NCT03852459
- Testing
- S-Ibuprofen, Vehicle
- Where
- United States
- Volunteers
- 251 people, healthy volunteers welcome
- Sponsor
- Aponia Laboratories, Inc.
Recovery Methods, Exercise and Recovery
Effects of Carnitine Supplementation on Exercise-Induced Muscle Damage: A Randomized Controlled Trial
This clinical study aims to investigate the effects of L-carnitine supplementation on recovery following high-intensity interval exercise in young athletes.
- Conditions
- Recovery Methods, Exercise and Recovery, Exercise Fatigue, Carnitine Ingestion
- Trial name
- NCT07492446
- Testing
- L-Carnitine
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istanbul Sabahattin Zaim University
TMD, Masticatory Muscle Pain
Pain, Central Sensitization and Psychoemotional State in Patients With Chronic Masticatory Muscle Pain
The aim of this study is to investigate the relationship of psychological aspects, selected blood parameters, pain, central sensitization, and muscle electromyography activity in patients with chronic masticatory muscle pain.
- Trial name
- NCT05676827
- Testing
- Diagnostic Criteria for Temporomandibular Disorders Clinical Examination, Blood test
- Where
- Poland
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
Tension-type Headache
Muscle Soreness and Stiffness in Patients With Chronic or Frequent Episodic Tension Type Headache.
The aim is to investigate muscle soreness and stiffness in patients with Chronic or Frequent Episodic Tension Type Headache before and after treatment with amitriptyline - and to compare the results with healthy individuals.
- Trial name
- NCT02746250
- Testing
- Amitriptyline
- Where
- Denmark
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
Muscle Soreness
Effects of Riboflavin in Mitigating Muscle Soreness in Ultra-marathon Athletes
The aim of this project is to investigate the effects of riboflavin, also known as vitamin B2, on preventing delayed onset muscle soreness (DOMS) in ultramarathon athletes through a randomized placebo-controlled study.
- Trial name
- NCT05907850
- Testing
- Riboflavin
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Steven Moore
Delayed Onset Muscle Soreness
Effects of Percussive Massage Treatment With Theragun on Post Exercise Delayed Onset Muscle Soreness
This project will be Randomized control trial conducted to check the effects of percussive massage treatment with theragun on pain and muscle length on post exercise delayed onset muscle soreness (DOMS) of calf muscles in healthy…
- Trial name
- NCT05026944
- Testing
- Percussive massage and static stretching exercises, static stretching exercises
- Where
- Pakistan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Myalgia, Trigger Point
Comparative Evaluation of Continuous and Pulse Mode of Ultrasound Therapy in Myalgia of Maxillofacial Region
Pain and trismus caused by Myalgia in masticatory muscles are one of the prime concerns for the patients. Various studies have been performed using US therapy for myofascial pain syndrome of head \& neck region.
- Trial name
- NCT05211245
- Testing
- therapeutic ultrasound
- Where
- India
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak