Clinical trials: Myanmar
Preterm Birth
Molecular Signature Children
Preterm birth (PTB) occurs before 37 weeks of gestation and is a major cause of neonatal mortality and morbidity. PTB results from heterogeneous influences.
- Trial name
- MSP_Ext (NCT03104673)
- Where
- Thailand
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Teenage Pregnancy
Teenage Pregnancies in Refugee and Migrant Adolescents on the Thai-Myanmar Border
This study is to explore perceptions, experiences, beliefs and knowledge around teenage pregnancy, motherhood, sexual and reproductive health, family planning and support structures adolescent refugees and migrants and to…
- Trial name
- NCT02890628
- Where
- Thailand
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Pregnancy
Molecular Signature Pregnancy
The primary goal of the study is to identify biomarkers from the molecular signature predictive of pre-term birth. This will be achieved through high frequency sampling and profiling throughout pregnancy.
- Trial name
- MSP (NCT02797327)
- Where
- Thailand
- Volunteers
- 430 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Helicobacter Pylori Infection
The Epidemiology and Optimal Treatment of Helicobacter Pylori in Myanmar
This study aims to: 1. Determine the prevalence of Helicobacter infection in Myanmar (this would be the largest ever series in the country) 2.
- Trial name
- NCT04132479
- Testing
- Clarithromycin 500mg, Amoxicillin 500mg, Tinidazole 500mg
- Where
- Burma
- Volunteers
- 313 people
- Sponsor
- Kirby Institute
Anemia Pregnancy
Anemia Pregnancy Outcome on the Thai-Myanmar Border
The global burden of maternal morbidity and mortality attributable to anemia is staggering, and this is especially true in low-resource settings.
- Trial name
- AnPREG (NCT03174652)
- Where
- Thailand
- Volunteers
- 13,520 people, healthy volunteers welcome
- Sponsor
- University of Oxford
The Prevalence of Scrub Typhus
Scrub Typhus RDT Study
Fever is one of most common presenting complaints in clinics in tropical countries. Rickettsial infections, enteric fever and leptospirosis are common and important causes of undifferentiated fever in Southeast Asia.
- Trial name
- NCT03269266
- Testing
- Scrub Typhus RDT Test
- Where
- 2 sites in Burma
- Volunteers
- 136 people
- Sponsor
- Myanmar Oxford Clinical Research Unit
Increased Drug Resistance, Asymptomatic Infection
Molecular Assessment of Drug Resistance Markers in Asymptomatic Malaria Cases and Malaria Antibody Kinetic
Detection of the drug resistance molecular markers for falciparum and vivax in Longitudinal follow-up samples collected in Shwegyin Township, Bago Region that is Artemisinin Resistance Containment Tier I.
- Conditions
- Increased Drug Resistance, Asymptomatic Infection, Malaria
- Trial name
- NCT02708199
- Volunteers
- 1,179 people, healthy volunteers welcome
- Sponsor
- Department of Medical Research, Lower Myanmar
Malaria
Effectiveness of a Community-delivered Integrated Malaria Elimination (CIME) Model in Myanmar
In Myanmar, community health workers, known as malaria volunteers, have played a key role in reducing the malaria burden in the malaria control phase, providing essential malaria services in rural areas where the coverage of…
- Trial name
- NCT04695886
- Testing
- Community-delivered Integrated Malaria Elimination (CIME) intervention model
- Volunteers
- 6,440 people, healthy volunteers welcome
- Sponsor
- Macfarlane Burnet Institute for Medical Research and Public Health Ltd
Amblyopia, Anisometropia
Enhanced Housing Photoscreeners 2WIN and GoCheckKids Compared in Burma and Alaska
"Adaptica" (Padova, Italy) designed a fixed-distance, dark portable tube with power and remote control for the "2WIN: photoscreener.
- Trial name
- NCT04068129
- Testing
- photoscreen
- Where
- United States
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Alaska Blind Child Discovery
Hepatitis C, Liver Cirrhoses
Simplified Monitoring Myanmar SM2 Study
The study will evaluate the proportion of patients with undetectable HCV RNA at 12 weeks post-treatment (SVR12) following a course of DAA therapy delivered using a simplified schedule of safety and virological monitoring.
- Conditions
- Hepatitis C, Liver Cirrhoses, Liver Inflammation, HIV Infections
- Trial name
- SM2 (NCT04113629)
- Testing
- HCV point of care machine
- Where
- Australia
- Volunteers
- 200 people
- Sponsor
- Kirby Institute
Plasmodium Falciparum Infection
Optimising Operational Use of Artemether-lumefantrine Comparing 3 Day Versus 5 Day
This is a randomised two arm study, comparing artemether-lumefantrine 3 days and 5 days treatment. Patients will be randomised in blocks of ten to one of the two treatment arms.
- Trial name
- AL3vs5 (NCT02020330)
- Testing
- Artemether-lumefantrine 3 days, Artemether-lumefantrine 5 days
- Where
- Burma
- Volunteers
- 150 people
- Sponsor
- University of Oxford
P. Falciparum Malaria
Compare the Effectiveness Between Existing Treatment and New Treatment
In camps for displaced persons located along the Thai-Myanmar border, mefloquine and artesunate combination therapy has been used since 1992.
- Trial name
- RDM (NCT01640587)
- Testing
- Mefloquine+Artesunate, Dihydroartemisinin-Piperaquine
- Where
- Thailand
- Volunteers
- 76 people
- Sponsor
- University of Oxford
Depression, Anxiety
Mental Health Assessment Project on the Thailand-Burma Border
The aim of the study is to determine the effectiveness of a transdiagnostic psychotherapy intervention - namely, Common Elements Treatment Approach (CETA) - in reducing the severity of mental health symptoms experienced by…
- Conditions
- Depression, Anxiety, Posttraumatic Stress
- Trial name
- MHAP (NCT01459068)
- Testing
- Common Elements Treatment Approach
- Where
- Thailand
- Volunteers
- 347 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Cardiovascular Diseases, Hypertension
Community-led Strategy to Reduce Cardiovascular Disease Risk Among Conflict-affected Populations
The goal of this study is to test a village health worker (VHW) based care model to reduce cardiovascular risk among adults in areas of eastern Myanmar affected by armed conflict.
- Conditions
- Cardiovascular Diseases, Hypertension, Diabetes
- Trial name
- NCT06819839
- Testing
- Village Health Worker (VHW) Care Model
- Where
- Burma
- Volunteers
- 213 people
- Sponsor
- Community Partners International
Hepatitis C
Hepatitis C Treatment Study in Myanmar
Hepatitis C is an important health problem in Myanmar affecting around 3% of the population. New drugs have been developed which have transformed the treatment of this disease around the world with very high success rates.
- Trial name
- NCT03158857
- Testing
- Sofosbuvir 400 mg
- Where
- Burma
- Sponsor
- Myanmar Oxford Clinical Research Unit
Daboia Siamensis Envenoming
Optimal Dose of Antivenom for Daboia Siamensis Envenomings
The aim of the study is to identify an 'optimal' initial dosing of the new Burma Pharmaceutical Industry (BPI) lyophilized mono-specific antivenom for patients with systemic Daboia siamensis envenoming.
- Trial name
- ODADS (NCT04210141)
- Testing
- lyophilized BPI viper antivenom
- Where
- Burma
- Volunteers
- 200 people
- Sponsor
- Myanmar Oxford Clinical Research Unit
Cognitive Change
Improving Clinical Decision Making Skills for Myanmar Physical Therapists by Series of Workshop
This study aims to improve the Clinical Decision Making (CDM) skills of a group of Myanmar physical therapists by series of educational workshops that will introduce them to and guide them through the decision making process by…
- Trial name
- NCT03149146
- Testing
- Clinical Decision Making (CDM) Workshop, Clinical Decision Making (CDM) Workbook
- Where
- Burma
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Drug Resistance, Plasmodium Falciparum Malaria
Molecular Surveillance of Artemisinin Resistance Malaria in Myanmar
Efficacy and safety of the artemisinin combination therapy (ACT) in uncomplicated falciparum malaria patients in Myanmar and artemisinin molecular markers analysis
- Trial name
- NCT02792816
- Testing
- First line antimalarial in Myanmar (artemether-lumefrantrine, dihydroartemisinin-piperaquine, and artesunate-mefloquine)
- Where
- Burma
- Volunteers
- 550 people
- Sponsor
- Department of Medical Research, Lower Myanmar
Malaria Diagnosis, Malaria,Falciparum
Evaluation of the Performance of a hsRDT Versus cRDT in Reactive Case Detection of Malaria Infections
A systematic review assessing the role, appropriateness and benefits of the active case detection strategy, both proactive and reactive, in low malaria transmission settings.
- Trial name
- NCT03511443
- Testing
- hsRDT
- Where
- Burma
- Volunteers
- 1,980 people, healthy volunteers welcome
- Sponsor
- University Research Co, LLC
Tuberculosis
PK Study of Anti-TB Drugs
This is a prospective descriptive and pharmacokinetic study will be conducted among newly diagnosed patients registered in the two SMRU TB clinics located on the Thai-Myanmar border.
- Trial name
- NCT02457208
- Testing
- Isoniazid (H), Rifampicin (R), Pyrazinamide (Z)
- Where
- Thailand
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Oxford