Clinical trials: Mycobacterium Avium Complex
Total Thyroidectomy, Hypocalcemia
Prevention of Postoperative Hypocalcemia of Oral Vitamin D Supplementation Before Total Thyroidectomy
The hypocalcemia after total thyroidectomy is one of common surgical complications. It may be asymptomatic, but patients can complain of dysfunction around the mouth or extremities, stiffness or convulsion in severe cases.
- Conditions
- Total Thyroidectomy, Hypocalcemia, Vitamin D Deficiency
- Trial name
- NCT05216419
- Testing
- Cholecalciferol
- Where
- 2 sites in South Korea
- Volunteers
- 108 people
- Sponsor
- Seoul National University Hospital
Depression
Mental Health in Adults and Children- Frugal Innovations (MAC-FI): Adult Depression Component
This stepped wedge, randomized controlled trial will test the effectiveness of a Supported Self-Management intervention for depression among adults in Vietnam.
- Trial name
- MAC-FI (NCT03001063)
- Testing
- Supported Self-Management, Enhanced treatment as usual
- Where
- Vietnam
- Volunteers
- 376 people
- Sponsor
- Simon Fraser University
Fibrous Dysplasia of Bone
Effect of Risedronate on Bone Morbidity in Fibrous Dysplasia of Bone
This trial is intended to test the efficacy of an oral bisphosphonate (risedronate) to decrease bone pain and improve radiological aspect in fibrous dysplasia of bone.
- Trial name
- PROFIDYS (NCT00445575)
- Testing
- risedronate
- Where
- 8 sites in Belgium, France and 2 more
- Volunteers
- 80 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
To Investigate the Inflammasome Response of Inflammatory and Resting Macrophage, To Compare the Difference of Inflammasome Response of Inflammatory Macrophage
The Role of Inflammasome in Inflammatory Macrophage in Mycobacterium Avium Complex-lung Disease and Mycobacterium Abscessus-lung Disease
1. To investigate the inflammasome response of inflammatory and resting macrophage derived from healthy human participants by stimulation using MAC or MAB bacilli. 2.
- Conditions
- To Investigate the Inflammasome Response of Inflammatory and Resting Macrophage, To Compare the Difference of Inflammasome Response of Inflammatory Macrophage, To Study the Diagnostic Aid From Immunological Markers in Inflammasome Response
- Trial name
- NCT02005094
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Difficult Airway, Difficult Intubation
LeHeR Maneuver vs Sniffing Position During Video Laryngoscopy in Predicted Difficult Airway
The left head rotation (LeHeR) maneuver, in which the head of the supine patient is rotated 45° to the left, is a simple, equipment-free technique proposed to improve the laryngeal view.
- Conditions
- Difficult Airway, Difficult Intubation, Video Laryngoscopy, Airway Management
- Trial name
- LeHeR-VL (NCT07902973)
- Testing
- Video laryngoscopy in the sniffing position, Left Head Rotation (LeHeR) maneuver
- Volunteers
- 40 people
- Sponsor
- Sakarya University
Treatment-refractory Mycobacterium Avium Complex-lung Disease (MAC-LD)
A Study of Bedaquiline Administered as Part of a Treatment Regimen With Clarithromycin and Ethambutol in Adult Patients With Treatment-refractory Mycobacterium Avium Complex-lung Disease (MAC-LD)
The purpose of the study is to evaluate the efficacy of bedaquiline (BDQ) compared with rifamycin when administered as part of a treatment regimen with clarithromycin (CAM) and ethambutol (EB) in adult participants with…
- Trial name
- NCT04630145
- Testing
- Bedaquiline, Clarithromycin, Ethambutol
- Where
- 55 sites in Japan, South Korea and 1 more
- Volunteers
- 129 people
- Sponsor
- Janssen Pharmaceutical K.K.
Intubation; Difficult or Failed
Flexible Tip Bougie vs Tube With Stylet for Intubation With Videolaryngoscopy.
Although VLs improve glottic visualization, on many occasions it may not be accompanied by intubation at the first attempt, because the endotracheal tube has to pass a sharp angle to enter the trachea.
- Trial name
- VIFLEXTIPOR (NCT05429125)
- Testing
- Endotracheal Tube with Stylet, Flexible Tip Bougie
- Where
- Spain
- Volunteers
- 140 people
- Sponsor
- Hospital Clinico Universitario de Santiago
Intensive Care Unit Syndrome
Different Volatile Anaesthetics and the Depth of Long Term ICU Sedation
The MIRUS system (TIM, Andernach, Germany) as well as the AnaConDa uses a reflector to conserve volatile anaesthetics (VA). Both systems can be paired with ICU ventilators, but MIRUS features an automated control of end-tidal VA…
- Trial name
- NCT03860129
- Testing
- Isoflurane, Sevoflurane, Desflurane
- Volunteers
- 30 people
- Sponsor
- Ruhr University of Bochum
Difficult Airway Intubation
C-MAC Video Laryngoscope and VS-CMAC Fiberoptic Stylet for Awake Endoscopic Intubation in Predicted Difficult Airways
An Anticipated difficult tracheal intubation is recommended to be managed performing the so called "Awake tracheal endoscopic intubation" (ATI) with the maintenance of patient's spontaneous breathing after an adequate sedation…
- Trial name
- NCT04532138
- Testing
- VS-CMAC Rigid Fiberoptic Stylet, C-MAC Video laryngoscope awake intubation
- Where
- Italy
- Volunteers
- 17 people
- Sponsor
- Università Politecnica delle Marche
Mycobacterium Avium-intracellulare Infection, HIV Infections
Study of Four Different Treatment Approaches for Patients Who Have Mycobacterium Avium Complex Disease (MAC) Plus AIDS
To compare the safety and efficacy of two doses of clarithromycin in combination with ethambutol and either rifabutin or clofazimine for the treatment of disseminated Mycobacterium avium Complex (MAC) disease in AIDS patients.
- Trial name
- NCT00001047
- Testing
- Ethambutol hydrochloride, Clarithromycin, Clofazimine
- Where
- 16 sites in United States
- Volunteers
- 400 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Endotracheal Intubation
Endotracheal Intubation in Prehospital Scenario
We therefore designed this randomized crossover study to compare C-MAC with Macintosh laryngoscope in emergency intubation performed by paramedics according to three different intubator positions.
- Trial name
- NCT02681835
- Testing
- C-MAC laryngoscope, Macintosh laryngoscope
- Where
- Poland
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Postoperative Vocal Cord Mobility, Recurrent Laryngeal Nerve Injury
C-MAC D-Blade vs Macintosh for Postoperative Vocal Cord Evaluation
This study compares two different laryngoscopes-the C-MAC D-Blade videolaryngoscope and the Macintosh direct laryngoscope-for evaluating vocal cord mobility after thyroidectomy.
- Trial name
- NCT07277985
- Testing
- Videolaryngoscope (C-MAC D-Blade), Direct Laryngoscope (Macintosh)
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Inonu University
Chronic Pain
Electrically Evoked Compound Action Potentials Human Observation Medtronic Algorithm Comparison Study
This is a prospective, multi-center, randomized, single-blind, cross-over, non-significant risk IDE research study to evaluate the in-clinic performance of a closed-loop algorithm in Spinal Cord Stimulation (SCS) therapy with an…
- Trial name
- ECHO-MAC (NCT04765735)
- Testing
- Open-loop testing, Closed-loop testing - External Spinal Cord Stimulator (SCS)
- Where
- 9 sites in United States
- Volunteers
- 52 people
- Sponsor
- MedtronicNeuro
Mycobacterium Avium-Intracellulare Infection, HIV Infections
A Study to Examine the Effects of Stopping Preventive Therapy for Disseminated Mycobacterium Avium Complex (DMAC) in HIV-Positive Patients
The purpose of this study is to evaluate the effects of stopping preventive therapy for DMAC in HIV-positive patients who (1) have been treated for DMAC for at least 12 months and are now free of any signs of DMAC for at least 16…
- Trial name
- NCT00000907
- Where
- 24 sites in United States
- Volunteers
- 50 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Monitored Anaesthesia Care, Loco-regional Chronic Subdural Hematoma Evacuation
Oral Melatonin as Premedication During MAC for Patients Undergoing Loco-regional Chronic Subdural Hematoma Evacuation
investigators assume that administration of preoperative melatonin will reduce the required dose of propofol in participants undergoing loco-regional chronic subdural hematoma evacuation, it may as well provide better…
- Trial name
- NCT03732963
- Testing
- Melatonin (Group M)
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Difficult Intubation, Cervical Injury Spine
Macintosh and D-Blade® in Simulated Difficult Airway
In the presented study, our aim was to compare intubation conditions regarding the modified Cormack \& Lehane score (CL) between the D-Blade® in indirect laryngoscopy or Macintosh blade in direct and indirect laryngoscopy with…
- Trial name
- NCT03403946
- Testing
- Macintosh blade, D-Blade, Intubation
- Where
- Germany
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Johann Wolfgang Goethe University Hospital
NTM Lung Infection Due to MAC
Open-label Safety Extension Study Assessing Safety and Tolerability of LAI in Patients Who Participated in Study INS-212
This is an open-label safety extension study to assess the safety and tolerability of once daily dosing of 590 mg Liposomal Amikacin for Inhalation (LAI) added to a multi-drug regimen in participants with nontuberculous…
- Trial name
- NCT02628600
- Testing
- LAI 590 mg, Multi-drug regimen
- Volunteers
- 163 people
- Sponsor
- Insmed Incorporated
Colorectal Cancer
A Clinical Study of Exploring Camrelizumab in the Treatment of Colorectal Mucinous Adenocarcinoma(MAC)
This is an open-label, single center, non-randomized, phase Ⅱ trial to evaluate safety and efficacy of using the combination treatment of Camrelizumab with anti-angiogenic drugs and Chemotherapy of metastatic colorectal mucinous…
- Trial name
- NCT04446091
- Testing
- Carilizumab + anti-angiogenic TKIs (available with fuquitinib, rigofenib, apatinib, etc.), Carilizumab + anti-angiogenic TKIs (available with fuquitinib, rigofenib, apatinib, etc.)+Irinotecan
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Zhejiang Cancer Hospital
Mycobacterium Avium-Intracellulare Infection, HIV Infections
An Open, Multicenter, Randomized, Dose-Ranging Study of Azithromycin in the Treatment of Disseminated Mycobacterium Avium-Intracellulare Complex Infection (MAC) in Patients With Acquired Immune Deficiency Syndrome (AIDS)
To evaluate the efficacy and safety of two doses of azithromycin given chronically for the treatment of Mycobacterium avium bacteremia in AIDS patients.
- Trial name
- NCT00002090
- Testing
- Azithromycin
- Where
- 6 sites in United States
- Sponsor
- Pfizer
Obesity, Morbid
Tracheal Intubation in Morbidly Obese (BMI>35) and in Lean (BMI<30) Patients Using McGrath MAC X-Blade
80 lean (BMI<35) and morbidly obese (BMI>35) patients undergoing elective surgery were enrolled in this prospective ransomİzed study were intubated using McGrath MAC X-Blade.
- Trial name
- NCT03759990
- Testing
- lean, obese
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Kocaeli University