Clinical trials: Mycobacterium Avium Complex
Intubation
Comparison of Different Stylet Angles for Orotracheal Intubation Using C-MAC® Video Laryngoscopes in Infants
The purpose of this study is to investigate whether the difference in stylet curvature affects the ease of tracheal intubation using C-MAC videolaryngoscope in infants under 1 year of age.
- Trial name
- NCT04745936
- Testing
- Style curve similar to natural curvature of endotracheal tube, Style curve similar to hockey stick shape
- Where
- South Korea
- Volunteers
- 114 people
- Sponsor
- Seoul National University Hospital
Endotracheal Intubation
Head and Neck Positions for Endotracheal Intubation Using a Videolaryngoscope
In this study, the investigators evaluate the effect of head positions (simple extension vs. sniffing position vs. head elevation) on endotracheal intubation using a videolaryngoscope.
- Trial name
- NCT05128968
- Testing
- endotracheal intubation
- Where
- South Korea
- Volunteers
- 174 people
- Sponsor
- SMG-SNU Boramae Medical Center
Mycobacterium Avium-intracellulare Infection, HIV Infections
Rifabutin Therapy for the Prevention of Mycobacterium Avium Complex (MAC) Bacteremia in AIDS Patients With CD4 Counts = or < 200: A Double-Blind, Placebo-Controlled Trial
The primary objectives of this trial are: To compare the safety of oral rifabutin versus placebo in the treatment of Mycobacterium avium complex (MAC) bacteremia in AIDS patients with CD4 counts less than or equal to 200…
- Trial name
- NCT00002032
- Testing
- Rifabutin
- Where
- 33 sites in United States
- Volunteers
- 750 people
- Sponsor
- Pharmacia
Mycobacterium Abscessus Infection, NTM Lung Infection Due to MAC
To Evaluate the Clinical Efficacy and Safety of Omadacycline in the Treatment of Mycobacterium Abscessus Infection.
The objective of this clinical trial is to evaluate the correlation between clinical efficacy and safety of omadacycline in the treatment of Mycobacterium abscessus infection through retrospective cohort studies.
- Trial name
- NTM (NCT07615309)
- Testing
- Omadacycline Treatment Group
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Beijing Chest Hospital
Video Laryngoscopic Device Usage in Novice Users
Comparison Study of the McGrath MAC Video Laryngoscope With the King Vision
In this study, the investigators compare the effectiveness of two relatively new video laryngoscopes, McGrath MAC (Covidien, Dublin Ireland) and the King Vision (King Systems, Noblesville, IN), by practitioners experienced in…
- Trial name
- NCT02316769
- Testing
- King Vision video laryngoscope, McGrath MAC video laryngoscope
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Cartilage Diseases
Non-interventional Study With NOVOCART® Basic in Patients Treated for Cartilage Defects in the Knee With MAC
Retrospective, multicenter, single arm, non-interventional study to assess the safety and Performance of NOVOCART Basic and the clinical outcome of MAC with NOVOCART Basic in patients treated for cartilage defects in the knee.
- Trial name
- NBasic (NCT03808623)
- Testing
- MAC with NOVOCART Basic
- Where
- 3 sites in Germany, Switzerland
- Volunteers
- 41 people
- Sponsor
- Tetec AG
Intubation;Difficult, Cervical Spinal Cord Injury
C-MAC Videolaryngoscope Intubation and Cervical Spine Motion
The aim of the study is to compare the effect of the C-MAC videolaryngoscope intubation technique vs. the conventional direct laryngoscope intubation technique on the cervical spine motion during intubation in patients with the…
- Trial name
- NCT03567902
- Testing
- C-MAC videolaryngoscope intubation, Direct laryngoscope intubation
- Volunteers
- 20 people
- Sponsor
- Seoul National University Hospital
Pulmonary Mycobacterium Avium Complex Infection, Bronchiectasis
RHB-204 for the Treatment of Pulmonary Mycobacterium Avium Complex Disease
A 2-part multi-center, Phase 3, randomized, double-blind, placebo-controlled, parallel group study to evaluate the efficacy and safety of RHB-204 in adult subjects with underlying nodular bronchiectasis and documented MAC lung…
- Conditions
- Pulmonary Mycobacterium Avium Complex Infection, Bronchiectasis, Lung Diseases
- Trial name
- CleaR-MAC (NCT04616924)
- Testing
- RHB-204
- Where
- 25 sites in United States
- Volunteers
- 12 people
- Sponsor
- RedHill Biopharma Limited
Mycobacterium Avium Complex Lung Disease
Azithromycin in the Treatment of M. Avium Complex Lung Disease
To determine the safety and efficacy of azithromycin in the treatment of lung infection with M.avium complex and M. abscessus lung disease.
- Trial name
- NCT00599079
- Testing
- Azithromycin
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- The University of Texas Health Science Center at Tyler
Percent of Vocal Cords (Glottic) Opening
Vocal Cord Views With the Classical Miller, Wis-Hipple and C-MAC Size 1 Blades in Young Children
The purpose of this study is to compare straight blades in obtaining best vocal cord view in children. The investigators will compare size 1 Classical Miller, size 1 Wis-Hipple, and size 1 C-MAC straight blades in young children.
- Trial name
- POGO (NCT03053583)
- Testing
- Laryngoscope blade
- Volunteers
- 96 people
- Sponsor
- State University of New York at Buffalo
Mitral Annulus Calcification, Rheumatic Heart Disease
Treating Severe Mitral Valve Annular or Valvular Calcification Using Shockwave Balloon SMARTWAVE
Mitral stenosis (MS) is a heavily symptomatic valvular heart disease. Common causes of MS included chronic rheumatic heart disease (CRHD) and mitral annular calcification (MAC).
- Trial name
- SMARTMAC (NCT06952374)
- Testing
- SmartWave Lithotripsy balloon
- Where
- Hong Kong
- Volunteers
- 10 people
- Sponsor
- Prince of Wales Hospital, Shatin, Hong Kong
Intubation
Comparison of Two Videolaryngoscopes (C-MAC vs Airtraq) for Awake Intubation
Patients with anticipated difficult airway are recommended to be managed with an awake tracheal intubation. Initially fibreoptic bronchoscopy was considered the gold standard, but in the last decade videolaryngoscopes have been…
- Trial name
- AWAKECMACTRA (NCT05428995)
- Testing
- C-MAC videolaryngoscope, Airtraq videolaryngoscope.
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Hospital Clinico Universitario de Santiago
Airway Complication of Anesthesia
A Comparison of Video Laryngoscopes and the Direct Laryngoscope in Simulated Normal and Difficult Infant Airway.
In Pediatric both manikin and human studies have suggested that the video laryngoscopy is equally suitable to facilitate intubation compared to the direct laryngoscopy.
- Trial name
- Kivi (NCT03230422)
- Testing
- normal airway, difficult airway
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- Johannes Gutenberg University Mainz
Blood Pressure, Heart Rate, Breathing Rate and Oxygen Level
Implementing Peri-operative Mobile Application for Contactless Vital Signs
The huge impact of the COVID-19 pandemic on global healthcare systems has prompted search for novel tools to stem the tide. New digital health tools can provide possible health solutions in this time of unprecedented medical…
- Trial name
- MAC-VITAL (NCT04648111)
- Testing
- Vital sign measurement
- Where
- Canada
- Volunteers
- 91 people
- Sponsor
- University Health Network, Toronto
Lung Infection, MAC Lung Disease
CLArithromycin Versus AZIthromycin in the Treatment of Mycobacterium Avium Complex (MAC) Lung Infections
MAC lung infections are a growing public health problem. The ATS / IDSA 2007 guidelines for the treatment of these non-tuberculous mycobacterial infections recommend the use of a macrolide or azalide (clarithromycin or…
- Trial name
- CLAZI (NCT03236987)
- Testing
- Clarithromycin 1000 MG, Azithromycin 250 mg, Rifampicin
- Where
- 3 sites in France
- Volunteers
- 424 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Intubation; Difficult or Failed
A.I. Supported Laryngoscopy and Endotracheal Intubation: a Manikin Study
LarynGuide is a newly developed AI-supported software for video laryngoscopy that supports the user through correct placement of endotracheal tube by means of audio-visual signals and warning of incorrect or potentially dangerous…
- Trial name
- aiTN (NCT06657417)
- Testing
- Video laryngoscopy, Video larnygoscopy
- Where
- Switzerland
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Schulthess Klinik
Cancer Patients Undergoing Chemotherapy or Radiotherapy
Therapeutic Effects of Traditional Chinese Medicine, Shen-Mai San in Cancer Patient Undergoing Chemotherapy or Radiotherapy
Using Shen-Mai-San for cancer patients undergoing chemotherapy or radiotherapy could help these people improve the quality of life.
- Trial name
- NCT01580358
- Testing
- Shen-Mai San, Starch
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Changhua Christian Hospital
Low Bispectral Index, Low Mean Arterial Blood Pressure
Randomized Trial of Alerts in Patients Demonstrating a "Triple Low"
The investigators propose to test the theory that smart alarms for the Triple Low State incorporated into a decision support system built into an electronic anesthesia record will prompt clinicians to intervene earlier in…
- Conditions
- Low Bispectral Index, Low Mean Arterial Blood Pressure, Low End-tidal Anesthetic Concentration
- Trial name
- NCT00998894
- Where
- United States
- Volunteers
- 9,846 people
- Sponsor
- The Cleveland Clinic
Difficult Mask Ventilation, Difficult Intubation
Effectiveness of C-MAC Video-stylet Versus Fiberoptic Bronchoscope for Awake Intubation
C-MAC- Video Stylet is a completely new type of video endoscope. It combines the advantages of both rigid and flexible intubation endoscopes.
- Trial name
- NCT04759287
- Testing
- C-MAC VS, flexible fibreoptic bronchoscope
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- rehab zayed
Breast Diseases
MAC vs TIVA Ambulatory Breast Augmentation
hypothesis: the combination of LA with remifentanil and ketofol [monitored anesthesia care (MAC)] for ambulatory breast augmentation may result in results in better QoR on day of surgery as compared with total i.v.
- Trial name
- NCT03764267
- Testing
- Remifentanil, general anesthetic
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ain Shams University