Clinical trials: Mycoplasma Genitalium Infection
Sexually Transmitted Infections (Not HIV or Hepatitis), Chlamydia Trachomatis Infection
Assess the Performance of Metagenomic Sequencing in the Diagnosis of STI (NGS-IST)
The main objective of the study will be to assess the performance of the Next-Generation-Sequencing (NGS) diagnostics of Chlamydia trachomatis and Neisseria gonorrhoeae compared to reference techniques.
- Conditions
- Sexually Transmitted Infections (Not HIV or Hepatitis), Chlamydia Trachomatis Infection, Neisseria Gonorrhoeae Infection, Mycoplasma Genitalium Infection
- Trial name
- NGS-IST (NCT05581160)
- Testing
- Assess the Performance of Metagenomic Sequencing in the Diagnosis of STI (NGS-IST)
- Where
- 2 sites in France
- Volunteers
- 332 people
- Sponsor
- Institut de Médecine et d'Epidémiologie Appliquée - Fondation Internationale Léon M'Ba
Sexual Assault and Rape, Sexually Transmitted Diseases
Prevalence of Sexually Transmitted Infections Among People Attending the Sexual Assault Centre in Oslo, Norway.
In this study the investigators seek to register the prevalence of sexually transmitted infections (STI) among people attending the Sexual Assault Centre in Oslo, Norway.
- Trial name
- NCT03132389
- Testing
- No intervention
- Where
- Norway
- Volunteers
- 640 people
- Sponsor
- University of Oslo
Sexually Transmitted Diseases, Bacterial
Self-taken Penile Meatal Swabs for Chlamydia, Gonorrhoea and Mycoplasma Genitalium Detection
Objectives: To compare self-taken penile meatal swabs versus first-catch urine samples for the detection of chlamydia, gonorrhoea and Mycoplasma genitalium from the penile urethra using nucleic acid amplification tests.
- Trial name
- Me-swab (NCT04244994)
- Testing
- Aptima-Combo2 and Aptima Mgen
- Where
- United Kingdom
- Volunteers
- 2,400 people
- Sponsor
- The Leeds Teaching Hospitals NHS Trust
Chlamydia Trachomatis Infection, Neisseria Gonorrheae Infection
Detection of Chlamydia Trachomatis, Neisseria Gonorrhoeae and Mycoplasma Genitalium by Real-time Multiplex Polymerase Chain Reaction (PCR) After Pooling Pharyngeal, Anorectal and Urinary Samples
This study aims to compare the sensitivity of detecting Chlamydia trachomatis, Neisseria gonorrhoeae and Mycoplasma genitalium by real-time multiplex PCR in a pooled analysis (i.e.
- Conditions
- Chlamydia Trachomatis Infection, Neisseria Gonorrheae Infection, Mycoplasma Genitalium Infection, Sensitivity
- Trial name
- ISTPOOL (NCT03568695)
- Testing
- Two samples on each of the three sites (pharynx, rectum, urine)
- Where
- 5 sites in France
- Volunteers
- 166 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Mycoplasma Genitalium Infection
Comparison of Standard of Care Guidelines for Mycoplasma Genitalium Infections Among Men With Non-gonococcal Urethritis
The purpose of this protocol is to determine the difference in clearance of Mycoplasma genitalium (MG) when using the Australian management protocol versus the current Centers of Disease Control (CDC) treatment guidelines for US…
- Trial name
- NCT03910907
- Testing
- Comparison of two standard of care regimens
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Alabama at Birmingham
Mycoplasma Genitalium Infection
Prospective, Monocentric, Interventional Study on Spontaneous Vaginal Clearance of Mycoplasma Genitalium
It is a prospective, monocentric, interventional study on spontaneous vaginal clearance of Mycoplasma genitalium. The main objective is to evaluate the spontaneous vaginal clearance of M.
- Trial name
- MYCOCLEAR (NCT04841408)
- Testing
- Vaginal self-sampling
- Where
- France
- Volunteers
- 69 people
- Sponsor
- University Hospital, Bordeaux
Sexually Transmitted Infection (STI), Mycoplasma Genitalium Infection
Community Burden of MG Infection
Objective: To assess the burden and the transmission dynamics of Mycoplasma genitalium (MG) infection in men who have sex with men in Hong Kong.
- Trial name
- NCT06793605
- Where
- Hong Kong
- Volunteers
- 920 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
HIV Infection Primary, Hepatitis, Viral, Human
Seville Cohort of People at Substantial Risk for HIV Infection on Pre-exposure Prophylaxis
Pre-exposure prophylaxis (PrEP) based on tenofovir represents a considerably new preventive intervention that has shown to significantly decrease the number of HIV infections while it enables early diagnosis of HIV and other…
- Conditions
- HIV Infection Primary, Hepatitis, Viral, Human, Sexually Transmitted Infections, Excluding HIV and Hepatitis
- Trial name
- SeVIHPrEP (NCT05492565)
- Testing
- Tenofovir Disoproxil Fumarate 300 MG Oral Tablet
- Where
- Spain
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Hospitales Universitarios Virgen del Rocío
Mycoplasma Genitalium, Non-gonococcal Urethritis (NGU)
"Sexual Health Assessment of TinidaZole Against M. Genitalium (SHAZAM)"
The objective is to estimate the efficacy of tinidazole for the treatment of Mycoplasma genitalium (MG) among male patients who have been diagnosed with non-gonococcal urethritis (NGU) at the Public Health - Seattle \&King County…
- Trial name
- SHAZAM (NCT07088419)
- Testing
- Tinidazole
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Washington
Men Who Have Sex With Men
Bacterial Sexually Transmitted Infections (STIs) Viability by Polymerase Chain Reaction (PCR)
It is a cross-sectional, without risk or constraint, monocentric study on the viability of the main bacterial sexually transmitted infections (STIs) in men who have sex with men (MSM).
- Trial name
- VISTH (NCT05959408)
- Testing
- Collection of throat swab, Collection of anal swab, Collection of first void urine
- Where
- France
- Volunteers
- 600 people
- Sponsor
- University Hospital, Bordeaux
Chlamydia Trachomatis Infection, Neisseria Gonorrhoeae Infection
A Study of the Cobas® Liat CT/NG/MG Test Versus Current Standard Practice for Managing Participants at Increased Risk of Sexually Transmitted Infections
This study is designed to assess the comparative clinical utility of the point of care cobas® liat CT/NG/MG to current standard practices in the diagnosis and treatment of urogenital infections with Chlamydia trachomatis (CT)…
- Conditions
- Chlamydia Trachomatis Infection, Neisseria Gonorrhoeae Infection, Mycoplasma Genitalium Infection
- Trial name
- NCT06369220
- Testing
- cobas® liat CT/NG/MG nucleic acid test, Standard of Care (SOC): Clinician's Standard Practice
- Where
- 4 sites in United States
- Volunteers
- 331 people
- Sponsor
- Hoffmann-La Roche
Sexually Transmitted Infections
STI/HIV Intervention Behavioral Intervention Program
The hypothesis is that a behavioral intervention tool adapted for the US military population will be acceptable and associated with a decrease in incident sexually transmitted infection (STI)/HIV rates and high-risk sexual…
- Trial name
- NCT04547413
- Testing
- STI/HIV Intervention Behavioral Intervention Program
- Where
- 2 sites in United States
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Madigan Army Medical Center
Anorectal Infection
Sexually Transmitted Infections With Mycoplasma Genitalium: Epidemiological, Clinical, Microbiological, Therapeutic Aspects
Infectious anorectitis is a poorly described clinical entity. Their epidemiology is poorly known, as are their clinical, diagnostic (diagnoses are regularly made in gastroenterology and new diagnostic tools are now available) and…
- Trial name
- IST_MG (NCT04954495)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Sexually Transmitted Infections (Not HIV or Hepatitis), Premature Birth
Genital Tract Infections, the Vaginal Microbiome and Gestational Age at Birth Among Pregnant Women in South Africa
This cohort study plans to investigate associations between the presence of multiple lower genital tract microorganisms in pregnancy and gestational age at birth.
- Conditions
- Sexually Transmitted Infections (Not HIV or Hepatitis), Premature Birth, Pregnancy; Infection, Microbial Colonization
- Trial name
- NCT06131749
- Testing
- No intervention
- Where
- South Africa
- Volunteers
- 603 people
- Sponsor
- University of Bern
Mycoplasma Genitalium Infection, Urethritis
Omadacycline for Treatment Refractory Mycoplasma Genitalium Urethritis
Urethritis from Mycoplasma genitalium is difficult to treat and often does not respond to first line therapy. In this case series study, individuals who have failed first line therapy will receive omadacycline (provided by…
- Trial name
- NCT07853742
- Testing
- Omadacycline Oral Tablet
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Montefiore Medical Center
Urethritis, Cervicitis
Time to Eradication of Mycoplasma Genitalium and Chlamydia Trachomatis After Treatment Commenced
The purpose of this on-going study is to study the number of days after antibiotic treatment has commenced (due to infection caused by the sexually transmitted bacteria Chlamydia trachomatis (CT) and Mycoplasma genitalium(Mg)) it…
- Conditions
- Urethritis, Cervicitis, Genital Mycoplasma Infection, Chlamydia Trachomatis
- Trial name
- NCT01661985
- Testing
- Azithromycin, Doxycycline, lymecycline
- Where
- Sweden
- Volunteers
- 160 people
- Sponsor
- Ostergotland County Council, Sweden
STI, Mycoplasma Genitalium Infection
Mycoplasma Genitalium Infection and Associated Antimicrobial Resistance Among HIV-infected Male in Hong Kong
Worldwide, Mycoplasma genitalium (MG) is increasingly reported as an emerging cause of sexually transmitted infections. Internationally, the prevalence of MG is higher in male with urethritis and community groups especially among…
- Trial name
- NCT05789134
- Testing
- self-sampling kits for STI testing in the laboratory
- Where
- Hong Kong
- Volunteers
- 573 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Mycoplasma Genitalium Infection
Lefamulin for M. Genitalium Treatment Failures
The purpose of this drug study is to find out whether the antibiotic lefamulin (trade name Xenleta) will cure Mycoplasma genitalium infections that have not been cured by prior antibiotics while finding out whether it is more…
- Trial name
- NCT05111002
- Testing
- Lefamulin, Doxycycline
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Washington