Clinical trials: Myelopathy Cervical
Cervical Spinal Cord Injury, Tetraplegia/Tetraparesis
Spinal Cord Associative Plasticity Study
Spinal cord associative plasticity (SCAP) is a combined cortical and spinal electrical stimulation technique developed to induce recovery of arm and hand function in spinal cord injury.
- Conditions
- Cervical Spinal Cord Injury, Tetraplegia/Tetraparesis, Cervical Myelopathy
- Trial name
- SCAP (NCT05163639)
- Testing
- Non-invasive pairing of cortical and spinal stimulation, Intraoperative pairing of cortical and spinal stimulation, Non-invasive repeated pairing of cortical and spinal stimulation (SCAP)
- Where
- 3 sites in United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Columbia University
Spinal Cord Injuries (Complete and Incomplete)
Multisite Transspinal Stimulation for Augmenting Recovery in Spinal Cord Injury
A well-established rehabilitation strategy for improvements of standing and walking ability in persons with spinal cord injury (SCI) is step training on a motorized treadmill with body weight support.
- Trial name
- NCT07204184
- Testing
- Multisite transspinal stimulation at rest, Multisite transspinal stimulation during robotic gait training
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Maria Knikou, PT, MBA, PhD
Hemodynamics Instability
Cardiac Output and Other Hemodynamic Changes With Prone Position in Cervical Myelopathy Patients Undergoing Surgery
Positioning a patient in prone position under anaesthesia significantly alters cardiovascular physiology. Cervical myelopathy patients are known to have autonomic dysfunction.
- Trial name
- NCT03027817
- Testing
- Prone Positioning
- Volunteers
- 30 people
- Sponsor
- Dhritiman Chakrabarti
10-second G&R Test
Evaluation of the Screening Effect of Artificial Intelligence Hand Activity Evaluation System for Cervical Spondylosis
The purpose of this study: 1. Build an artificial intelligence screening tool for cervical spondylosis based on hand function analysis; 2. Verify the accuracy of cervical spondylosis screening tools.
- Trial name
- NCT06041542
- Testing
- 10-second hand grip and release test
- Where
- China
- Volunteers
- 1,380 people, healthy volunteers welcome
- Sponsor
- Guangdong Provincial People's Hospital
Degenerative Cervical Spinal Stenosis
A Novel Surgical Criteria for Degenerative Cervical Myelopathy in Chinese Ethnicity
Degenerative Cervical Myelopathy (DCM) is an age-related irreversible degenerative disease predominantly affecting the elderly aged 50 and over.
- Trial name
- NCT06528730
- Testing
- DCM
- Where
- Hong Kong
- Volunteers
- 100 people
- Sponsor
- The University of Hong Kong
Spinal Cord Injuries, Spinal Cord Diseases
Stimulation With Wire Leads to Restore Cough
The purpose of this trial is to determine the efficacy of spinal cord stimulation, using wire leads, to produce an effective cough in patients with spinal cord injuries.
- Conditions
- Spinal Cord Injuries, Spinal Cord Diseases, Paralysis, Central Nervous System Diseases
- Trial name
- NCT01659541
- Testing
- Expiratory muscle stimulator, Implantation of device
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- MetroHealth Medical Center
Cervical Myelopathy
Effect of Tranexamic Acid on Reducing Postoperative Blood Loss in Cervical Laminoplasty
The purpose is to evaluate the efficacy of tranexamic acid in cervical laminoplasty; the surgical procedure used was identical in all cases.
- Trial name
- NCT01027546
- Testing
- Tranexamic Acid
- Volunteers
- 40 people
- Sponsor
- Yodakubo Hospital
Advanced Solid Tumors
A Study of BMS-986484 Alone and Combination Therapy in Participants With Advanced Solid Tumors
The purpose of this study is to assess the safety and tolerability of BMS-986484 administered alone, in combination with nivolumab in participants with advanced/metastatic solid tumors including non-small cell lung cancer…
- Trial name
- NCT06544655
- Testing
- BMS-986484, Nivolumab, Oxaliplatin
- Where
- 9 sites in United States, Australia and 1 more
- Volunteers
- 213 people
- Sponsor
- Bristol-Myers Squibb
End of Life, Cancer
Comparative Effectiveness Trial of Two Supportive Cancer Care Delivery Models for Adults With Cancer
This cluster-randomized comparative effectiveness trial compares a technology-based supportive cancer care (SCC) approach with a redesigned team-based supportive cancer care (SCC) approach.
- Trial name
- NCT05297734
- Testing
- Receive technology-based supportive cancer care, Receive redesigned team-based supportive cancer care
- Where
- 17 sites in United States
- Volunteers
- 2,996 people
- Sponsor
- Stanford University
Cervical Spondylosis
A Magnetic Resonance Imaging Study of Patients With Cervical Spondylosis
This study aims at evaluating spinal cord structure using diffusion tensor imaging in patients with cervical spondylosis.
- Trial name
- Tractocervical (NCT01243684)
- Testing
- DTI - Diffusor Tensor Imaging
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cervical Myelopathy
The Study About the Efficacy of Oral Limaprost After Surgery for Cervical Myelopathy
The limaprost alfadex can improve the surgical outcomes in patients with cervical myelopathy.
- Trial name
- NCT02125981
- Testing
- Limaprost
- Where
- South Korea
- Volunteers
- 160 people
- Sponsor
- Seoul National University Hospital
Cervical Myelopathy
Proprioceptive Deficits in Degenerative Cervical Myelopathy
Proprioceptive deficits in degenerative cervical myelopathy (DCM) is a progressive neurological deficits in somatosensory and motor function which affects the body balance and motor control.
- Trial name
- NCT05183971
- Testing
- Proprioceptive Functional Analysis System
- Where
- Hong Kong
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Nerve Transfer
Nerve Transfers for Restoration of Hand Function in Cervical Spinal Cord Injury: Effects and Influencing Factors
The goal of this observational study is to learn about influencing factors on the clinical outcomes of nerve transfers used to restore hand function in patients with cervical spinal cord injury (CSCI).
- Trial name
- NCT06596629
- Where
- Netherlands
- Volunteers
- 19 people
- Sponsor
- Roessingh Research and Development
Incomplete Spinal Cord Injury
The Use of Electromagnetic Field (EMF) Treatment in Chronic Spinal Cord Injury (SCI) Patients
The purpose of this study is to further establish safety and efficacy of the BQ EMF treatment of chronic SCI subjects who demonstrate stability in The Graded and Redefined Assessment of Strength, Sensibility and Prehension…
- Trial name
- NCT04050696
- Testing
- BQ 1.2
- Where
- 3 sites in United States, Israel
- Volunteers
- 8 people
- Sponsor
- BrainQ Technologies Ltd.