Clinical trials: Myocardial Ischemia
Myocardial Infarction, Coronary Disease
The MI-HEART Project
The purpose of the study is to examine ways in which a clinical information system can help patients better recognize the signs and symptoms of an acute myocardial infarction (heart attack) and to take actions to decrease…
- Trial name
- NCT00013741
- Testing
- Tailored Education Messages
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- National Library of Medicine (NLM)
Coronary Artery Disease, Arrhythmia
Effect of Supplemental Intake of Omega-3 Polyunsaturated Fatty Acids on the Rate and Complexity of Spontaneously Occurring Ventricular and Supraventricular Arrhythmias in Patients With Implantable Cardioverter Defibrillator (ICD) - A Randomized Clinical Trial
We hypothesize that oral supplementation with omega-3 PUFA will decrease occurrence of arrhythmic events among post-MI, ICD recipients.
- Trial name
- NCT00290056
- Testing
- Eicosapentanoic acid (EPA) and Docosahexanoic acid (DHA).
- Where
- 2 sites in Israel
- Volunteers
- 105 people
- Sponsor
- Sheba Medical Center
Coronary Heart Disease, Stroke
Surgical Manipulation of the Aorta and Cerebral Infarction
The purpose of the study is to compare two surgical strategies for coronary artery bypass grafting with respect to the occurrence of cerebral infarctions made visible by magnetic resonance imaging
- Conditions
- Coronary Heart Disease, Stroke, Cerebral Infarction
- Trial name
- NCT00558779
- Testing
- OBCAB (Off Pump Coronary Artery Bypass Grafting), CABG (coronary artery bypass grafting)
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- University of Wuerzburg
STEMI - ST Elevation Myocardial Infarction
ST-segment Elevation Not Associated With Acute Cardiac Necrosis (LESTONNAC)
Patients with chest pain and persistent ST segment elevation (STE) may not have acute coronary occlusions or serum troponin curves suggestive of acute necrosis.
- Trial name
- LESTONNAC (NCT05689970)
- Testing
- AI platform to detect ST elevation in ECG
- Where
- 7 sites in Spain
- Volunteers
- 420 people
- Sponsor
- Idoven 1903 S.L.
Myocardial Ischemia, Heart Defects, Congenital
Spectroscopic Assessment of Myocardial Oxygenation Changes in Pediatric Heart Surgery
The goal of this observational study is to investigate the ability of the SpectroCor Tissue Oxygenation Monitor and its accessory SpectroCor Sensor to observe and monitor changes in cardiac oxygen availability in pediatric…
- Conditions
- Myocardial Ischemia, Heart Defects, Congenital, Reperfusion Injury, Myocardial
- Trial name
- NCT07785141
- Where
- Finland
- Volunteers
- 30 people
- Sponsor
- Spectrocor
Myocardial Ischaemia, Coronary Artery Disease
Evaluation of Effects of Rosuvastatin 40mg on Myocardial Ischemia in Subjects With Coronary Artery Disease
The purpose of this study is to determine whether treatment with 40mg of Rosuvastatin for 8 weeks will reduce the number of episodes of myocardial ischaemia suffered in subjects with coronary artery disease.
- Trial name
- NCT00657527
- Testing
- Rosuvastatin, Cholesterol lowering diet
- Volunteers
- 280 people
- Sponsor
- AstraZeneca
Stroke, Ischemic, Stroke, Acute
Ischemic Strokes While on NOAC - How Compliance Matters
This study is aimed to depict the epidemiological trend, aetiologies, clinical characteristics, treatment options of IS-NOAC in face of the rapidly increasing NOAC usage.
- Conditions
- Stroke, Ischemic, Stroke, Acute, Stroke Syndrome, Stroke, Cardiovascular
- Trial name
- NCT04607070
- Where
- Hong Kong
- Volunteers
- 91 people
- Sponsor
- Chinese University of Hong Kong
Coronary Artery Disease, Coronary Artery Bypass Grafting
Effects of PEEP on Parameters of Tissue Perfusion in Patients Post Cardiac Surgery
Pulmonary dysfunction is a condition inherent in cardiac surgery because of various interventions, such as general anesthesia, a median sternotomy, cardiopulmonary bypass and establishment of internal thoracic artery dissection.
- Conditions
- Coronary Artery Disease, Coronary Artery Bypass Grafting, Acute Lung Injury
- Trial name
- NCT03753022
- Testing
- Group G5, Group G10, Group G15
- Volunteers
- 125 people
- Sponsor
- Federal University of São Paulo
Chronic Total Occlusion (CTO)
FAPI Imaging Assessment of Chronic Total Occlusion
This registry will include consecutive patients presenting with at least one chronic total coronary occlusion (CTO) identified via coronary angiography or cardiac computed tomography angiography (CCTA) at our center.
- Trial name
- FACT (NCT06655922)
- Testing
- FAPI Imaging
- Where
- 2 sites in China
- Volunteers
- 167 people
- Sponsor
- Lin Zhao
Coronary Artery Disease, Congestive Heart Failure
Cardiac Stem Cell Infusion in Patients With Ischemic CardiOmyopathy (SCIPIO)
The purpose of this study is to investigate the safety of intracoronary cardiac stem cells (CSCs) therapy in humans. Currently, there is no effective intervention to regenerate (regrow) dead heart muscle after a heart attack.
- Trial name
- SCIPIO (NCT00474461)
- Testing
- Treatment group
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Louisville
Coronary Stenosis
Bifurcation Stenting Using 2 Link Stent Nobori Versus 3 Link Stent Xience
The primary objective of this study is to make a comparison of safety and efficacy of DESs with different link number (2-link Nobori and 3-link Xience) in patients with de novo true bifurcation lesions.
- Trial name
- BEGIN (NCT01574586)
- Testing
- Bifurcation stenting
- Where
- Japan
- Volunteers
- 240 people
- Sponsor
- Kurashiki Central Hospital
Angina Pectoris
Absorption and Pharmacokinetics of Nitroglycerin to a New Formulation
The study evaluate the absorption rate of different sublingual formulation of nitroglycerine (NTG) either in the form of available tablets or a new rapid absorbable gelation capsule formulation "NTG1523" by determining T-max and…
- Trial name
- NCT03777605
- Testing
- Nitroglycerin 0.4 MG
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Kolding Sygehus
Mitral Valve Insufficiency, Coronary Stenosis
Impact of Mitral Regurgitation on Coronary Haemodynamics and Instantaneous Effect of Transcatheter Mitral Valve Repair
In the present study, the investigators aim to use the in-vivo Transcatheter Mitral Valve Repair (TMVR) model to determine how Mitral Regurgitation (MR) affects coronary hemodynamics in patients affected with severe MR and…
- Conditions
- Mitral Valve Insufficiency, Coronary Stenosis, Mitral Regurgitation, Coronary Artery Disease
- Trial name
- MitraFLOW (NCT04245956)
- Testing
- Measure of hemodynamic indices in a stenosed coronary artery using a pressure wire
- Where
- Switzerland
- Volunteers
- 1 people
- Sponsor
- University Hospital, Geneva
Healthy
Trial to Assess the Effects of Different Trans-fatty Acids on Endothelial Function in Humans
The aim of the study is to compare a diet rich in trans fatty acids (TFA) from ruminant sources with a diet rich in TFA from hydrogenated vegetable oils (PHVO) in regard to their effects on cardiovascular risk markers…
- Trial name
- NCT00933322
- Testing
- diet enriched with industrial trans fatty acids, diet enriched with ruminant trans fatty acids, diet without any trans fatty acids
- Where
- Switzerland
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Coronary Artery Disease
Dietary Intervention to Stop COronary Atherosclerosis in Computed Tomography
The aim of the study is to determine, wheather strict dietary intervention with the use of the DASH diet atop of optimal medical treatment reduces previously diagnosed coronary atherosclerotic lesions assessed witch coronary…
- Trial name
- DISCO-CT (NCT02571803)
- Testing
- Dietary And Lifestyle Counseling, Optimal Medical Treatment
- Where
- Poland
- Volunteers
- 180 people
- Sponsor
- National Institute of Cardiology, Warsaw, Poland
Coronary Artery Disease
PLATINUM Trial to Assess the PROMUS Element Stent System for Treatment of De Novo Coronary Artery Lesions-Pharmacokinetics (PLATINUM PK)
The purpose of this study is to evaluate the safety and effectiveness of the PROMUS Element™ Everolimus-Eluting Coronary Stent System for the treatment of patients with up to 2 de novo atherosclerotic coronary artery lesions.
- Trial name
- PLATINUM PK (NCT01510327)
- Testing
- PROMUS Element Everolimus-Eluting Coronary Stent System, Aspirin, Thienopyridine
- Where
- 5 sites in United States, Japan
- Volunteers
- 22 people
- Sponsor
- Boston Scientific Corporation
Coronary Artery Disease, Arrhythmias, Cardiac
Prognosis Prediction System of Patients With Cardiovascular and Cerebrovascular Diseases Based on Multi-omics
The etiology and specific pathogenesis of many cardiovascular diseases such as coronary atherosclerosis, cardiomyopathy, atrial fibrillation, and stroke are still unclear.
- Conditions
- Coronary Artery Disease, Arrhythmias, Cardiac, Heart Valve Diseases, Aortic Dissection
- Trial name
- PROSPECT (NCT06001073)
- Testing
- Observational; No Interventions were given.
- Where
- China
- Volunteers
- 25,000 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Acute Coronary Syndrome, Angioplasty, Transluminal, Percutaneous Coronary
Early Use of Rosuvastatin in Acute Coronary Syndromes: Targeting Platelet-Leukocyte Interactions
The central hypothesis for this work is that platelet - leukocyte interactions play a critical role in the pathogenesis of acute ischemic events.
- Conditions
- Acute Coronary Syndrome, Angioplasty, Transluminal, Percutaneous Coronary, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Blood Platelets
- Trial name
- NCT01241903
- Testing
- rosuvastatin
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Susan Smyth
Sleep Quality, Coronary Heart Disease
Effect of Atlas Cedarwood Essential Oil Aromatherapy on Sleep Quality Among Patients With Coronary Heart Disease
Sleep-wake disturbances were found to be a common problem among patients with CHD either earlier during hospitalization or/ and after discharge Although there is an evidence that sleep-wake disturbanes occur in high rate among…
- Trial name
- NCT03830554
- Testing
- Organic Atlas cedar wood essential oil (Cedrus Atantica)
- Where
- Jordan
- Volunteers
- 96 people
- Sponsor
- Rawan Alghzawi
Cardiovascular Diseases, Heart Diseases
Epidemiology of Coronary Calcification in the Elderly
To investigate the prevalence and prognostic value of subclinical atherosclerosis in the Pittsburgh SHEP cohort and a cohort of normal controls.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Coronary Arteriosclerosis, Coronary Disease
- Trial name
- NCT00005756
- Sponsor
- University of Pittsburgh
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