Clinical trials: Myocardial Ischemia
Exercise Test
Virtual Group Motivation in Exercise Treadmill Testing
Exercise stress testing is the most frequently used clinical tool for assessment of coronary artery disease. To ensure a high validity of the results, a good Patient compliance is crucial.
- Trial name
- NCT03704493
- Testing
- Video Group
- Volunteers
- 108 people
- Sponsor
- Kantonsspital Baden
Coronary Artery Disease
Drug-coated Balloons Versus Drug-eluting Stents for de Novo Small-vessel Coronary Artery Disease
This prospective, multicenter observational study will compare the safety and clinical outcomes of drug-coated balloon angioplasty and second-generation drug-eluting stent implantation in patients undergoing percutaneous coronary…
- Trial name
- DCB-SVD (NCT07839806)
- Testing
- Drug coated balloon, Drug Eluting stent
- Where
- Greece
- Volunteers
- 230 people
- Sponsor
- National and Kapodistrian University of Athens
Coronary Artery Disease
Assessment of Catheter-based Interrogation and Standard Techniques for Fractional Flow Reserve Measurement
This study will assess the differences between Fractional Flow Reserve (FFR) measurements made by the Navvus catheter and a commercially available pressure guidewire in up to 240 subjects where FFR is clinically indicated.
- Trial name
- ACIST-FFR (NCT02577484)
- Testing
- RXi System, Pressure Wire
- Where
- 12 sites in United States
- Volunteers
- 240 people
- Sponsor
- Acist Medical Systems
Acute Myocardial Infarction
Effects of Nitric Oxide for Inhalation in Myocardial Infarction Size
The purpose of this study is to determine the effects of Nitric Oxide for Inhalation on Myocardial Infarction Size.
- Trial name
- NOMI (NCT01398384)
- Testing
- Nitric Oxide, MI size at 48-72 hours
- Where
- 4 sites in Belgium, Hungary and 1 more
- Volunteers
- 250 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Coronary Artery Disease
Is Our Microbiome a Predictor of Cardiac Risk
The purpose of this study is to determine a relationship between a person's flora/bacteria in their gut (the intestinal microbiome) and their risk of cardiovascular disease.
- Trial name
- NCT02013284
- Where
- United States
- Volunteers
- 700 people
- Sponsor
- Mayo Clinic
Stable Angina
Treadmill Cardiovascular Safety Study of Erenumab (AMG 334)
A phase 2a, multicenter, randomized, double-blind, placebo-controlled study in adults with stable angina to evaluate the effect of erenumab (AMG 334) compared to placebo on exercise time during an exercise treadmill test.
- Trial name
- NCT02575833
- Testing
- Erenumab
- Where
- 33 sites in United States, Bulgaria and 8 more
- Volunteers
- 89 people
- Sponsor
- Amgen
Coronary Artery Disease
DynamX Bioadaptor Global Post-Market Registry: Clinical Trial of the Elixir Medical DynamX Coronary Bioadaptor System
The goal of this registry is to confirm the safety, and performance of the DynamX Coronary Bioadaptor System in patients with coronary artery disease.
- Trial name
- Bio-RESTORE (NCT06074549)
- Testing
- DynamX Novolimus-eluting Coronary Bioadaptor System
- Where
- 17 sites in Austria, Curacao and 7 more
- Volunteers
- 5,000 people
- Sponsor
- Elixir Medical Corporation
Coronary Artery Disease
Intravenous Fish Oil in Critically Ill Cardiac Patients
A large body of evidence has accumulated showing that n-3 PUFAs exert extensive cardiac effects. The development of commercial solutions of FO opens perspectives for therapeutic applications in patients with acute cardiac…
- Trial name
- FO-cardiac (NCT00516178)
- Testing
- Fish oil emulsion, Saline
- Where
- 2 sites in Switzerland
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
ST-segment Elevation Myocardial Infarction (STEMI)
PRasugrEl Monotherapy Following prImary percUtaneous Coronary Intervention for ST-elevation Myocardial Infarction
The aim of this study is to evaluate the safety of prasugrel monotherapy without aspirin versus 12-month dual antiplatelet therapy (DAPT) in patients with STEMI using platinum-chrome everolimus-eluting stent (PtCr-EES: SYNERGYTM).
- Trial name
- PREMIUM (NCT05709626)
- Testing
- No aspirin (Prasugurel monotherapy), 12-month DAPT
- Where
- Japan
- Volunteers
- 2,258 people
- Sponsor
- Kindai University
Coronary Disease
Evaluation of HealinG of Polymer-Free Biomlimus A9-Coated Stent by Optical Coherence Tomography (EGO-BIOFREEDOM)
Since polymers have been identified as a possible cause of late complications of drug eluting stents, new stents are being designed to improve polymers' biocompatibility or to bond drugs on stents without polymers.
- Trial name
- NCT01760876
- Testing
- coronary intervention
- Where
- Hong Kong
- Volunteers
- 106 people
- Sponsor
- Professor Stephen Lee
Myocardial Infarction, Peripheral Vascular Disease
Lowering the Risk of Operative Complications Using Atorvastatin Loading Dose
Patients submitted to noncardiac surgeries are at increased risk of serious cardiovascular complications. Statins have shown to lower cholesterol levels and reduce cardiovascular events in other scenarios.
- Conditions
- Myocardial Infarction, Peripheral Vascular Disease, Aortic Aneurism
- Trial name
- LOAD (NCT01543555)
- Testing
- Atorvastatin
- Where
- Brazil
- Volunteers
- 648 people
- Sponsor
- Hospital do Coracao
Coronary Artery Disease
Coronary Stenting and Coronary Bypass Grafting at the Same Time in a Specialty Built Operating Room
This study will combine coronary stenting with minimally invasive robotic coronary bypass surgery, accomplished with the use of the da Vinci robot, to restore blood flow to occluded coronary arteries.
- Trial name
- NCT00366015
- Testing
- Robotic-assisted Coronary Surgical Revascularization, PCI- Drug Eluting Stents
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
STEMI
The Coronary Sinus Balloon Pump in STEMI
This study is a prospective, multicenter, randomized controlled clinical trial designed to evaluate the safety and efficacy of the coronary sinus balloon pump (manufactured by Shanghai MicroPort Rotapace Medical Technology Co.…
- Trial name
- REVIVE-RCT (NCT07354035)
- Testing
- The coronary sinus balloon pump, Percutaneous Coronary Intervention (PCI)
- Volunteers
- 177 people
- Sponsor
- Shanghai MicroPort Rhythm MedTech Co., Ltd.
Coronary Arteriosclerosis
P2Y12 Inhibitors Utilization in Bifurcation and Chronic Total Occlusion PCI
Prasugrel and ticagrelor were both associated with a significant reduction in the risk of MACE in patients undergoing PCI for an ACS, mostly through a reduced stent thrombosis.
- Trial name
- P2BiTO (NCT01967615)
- Volunteers
- 4,500 people
- Sponsor
- G. d'Annunzio University
mHealth, Telemedicine
Mobile App and Digital System for Patients After Myocardial Infarction
The treatment of acute myocardial infarction (MI) in Poland is at the level of standardized European care. However, the first months after MI are crucial from the perspective of patient's prognosis.
- Trial name
- afterAMI (NCT04793425)
- Testing
- Mobile application (afterAMI)
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Medical University of Warsaw
ST Elevation Myocardial Infarction
NP202 for Treatment of Post -STEMI Left Ventricular Systolic Dysfunction
NP202 is an experimental drug being developed by Armaron Bio Pty Ltd for potential use as a treatment for people after they have had a heart attack (MI).
- Trial name
- NCT02557217
- Testing
- NP202
- Where
- Australia
- Volunteers
- 120 people
- Sponsor
- Armaron Bio Pty Ltd
Periodontal Diseases, Cardiovascular Diseases
Connecting Periodontal and Coronary Artery Disease Via the Inflammatory State of the Body
Cardiovascular disease is one of the leading causes of death in the United States and the world. Many interventions relating to prevention have been emphasized as more risk factors for this devastating disease are discovered.
- Trial name
- NCT03042117
- Testing
- periodontal probing
- Volunteers
- healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center
Cardiogenic Shock
Pharmacokinetic Modelling of Levosimendan in Adults
In the light of current knowledge of the PK of levosimendan and its use in ECMO weaning, deciphering the mechanisms of inter-individual variability in exposure and response to levosimendan appears essential in order to better…
- Trial name
- MILADECMO (NCT06993584)
- Testing
- Adult patients in cardiogenic shock
- Where
- 3 sites in France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Rouen
Myocardial Infarction
Innovative Stratification of Arrhythmic Risk (ISAR-Trial): Diabetes Mellitus
The purpose of this study was to evaluate the performance of established and new risk predictors in predicting mortality in post-infarction patients suffering from diabetes mellitus
- Trial name
- NCT00196235
- Where
- 2 sites in Germany
- Volunteers
- 650 people
- Sponsor
- Deutsches Herzzentrum Muenchen
Coronary Artery Disease
Portuguese Study on The Evaluation of FFR Guided Treatment of Coronary Disease
Functional evaluation of coronary lesions, through the evaluation of fractional flow reserve (FFR) with pressure-wire in patients with coronary artery disease (CAD) was evaluated in a randomised trial - the FAME trial - where it…
- Trial name
- POST-IT (NCT01835808)
- Testing
- Fractional flow reserve (St. Jude Medical pressure-wire)
- Where
- Portugal
- Volunteers
- 918 people
- Sponsor
- Portuguese Society of Cardiology
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.