Clinical trials: Myocardial Ischemia
Acute Coronary Syndrome
Cardiology-Emergency Medicine Cardiac Biomarker Research Initiative
This is an OBSERVATIONAL Specimen procurement and data collections trial for acute coronary syndrome that will be conducted in the Emergency Department at Henry Ford Hospital.
- Trial name
- ED~Cards (NCT01984853)
- Testing
- OBSERVATIONAL REGISTRY
- Where
- United States
- Volunteers
- 575 people
- Sponsor
- Henry Ford Health System
Unprotected Left Main Coronary Artery Disease
Comparison of HYBRID Versus Two-Stent Strategies in Unprotected True Left MAIN Bifurcation
The number of deaths from heart disease is rising globally, particularly in developing countries. This condition involves the narrowing of arteries that supply blood to the heart.
- Trial name
- HYBRID MAIN (NCT07159737)
- Testing
- Two-stent strategy, Hybrid Strategy
- Volunteers
- 800 people
- Sponsor
- Hospital Sultanah Bahiyah
Myocardial Ischemia
SmartCardia for the Detection of Myocardial Ischemia in Coronary Artery Disease
Coronary artery disease and myocardial ischemia are among the leading causes of death and disability in the Westerns countries. Timely and accurate diagnosis of myocardial ischemia at the moment of symptom onset is crucial and…
- Trial name
- Smartschemia (NCT04810845)
- Testing
- Application of Class II A device SmartCardia
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Coronary Artery Disease
Photochemical Tissue Passivation Treatment of Saphenous Vein Grafts in CABG
Early feasibility study of the DurVena Photochemical Tissue Passivation (PTP) device for treatment of saphenous vein grafts in participants undergoing elective coronary artery bypass graft (CABG) surgery.
- Trial name
- NCT06150872
- Testing
- DurVena Photochemical Tissue Passivation
- Where
- Uzbekistan
- Volunteers
- 4 people
- Sponsor
- DurVena, Inc.
Coronary Artery Disease, Aspirin Resistance
Dual Antiplatelet Therapy in Patients With Aspirin Resistance Following Coronary Artery Bypass Grafting
Reactive platelet hyperactivity following coronary artery bypass grafting (CABG) might lead to thrombotic complications and major ischemic cardiac events.
- Trial name
- NCT01159639
- Testing
- Clopidogrel
- Where
- Croatia
- Volunteers
- 200 people
- Sponsor
- University of Zagreb
Diastolic Dysfunction, Coronary Artery Disease
Study of the Effect of Inhaled Anesthetics on Diastolic Heart Function Using a Doppler-derived Efficiency Index
The purpose of this study is to determine the effect of inhaled anesthetic drugs upon diastolic heart function (heart suction and filling performance) in patients who are undergoing coronary bypass surgery.
- Conditions
- Diastolic Dysfunction, Coronary Artery Disease, General Anesthesia
- Trial name
- NCT00907439
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Washington University School of Medicine
Complication, Postoperative
Perioperative Fluid Management: Goal-directed Versus Restrictive Strategy
There is no ideal "cookbook recipe" for fluid prescription that would fit every surgical patient. In this study, the investigators working hypothesis is that the adoption of an integrative algorithm for perioperative fluid and…
- Trial name
- NCT02625701
- Testing
- Goal-directed therapy, Restrictive fluid therapy
- Where
- Switzerland
- Volunteers
- 400 people
- Sponsor
- University Hospital, Geneva
Coronary Artery Disease
Correlation of Cardiac Computed Tomography Angiography Dimensions and Ethnicity in Trinidad
The aim of this study is to compare coronary artery dimensions on Cardiac CT angiography amongst different ethnicities in Trinidad.
- Trial name
- CADET (NCT04774861)
- Where
- Trinidad and Tobago
- Volunteers
- 170 people
- Sponsor
- The University of The West Indies
Troponin, Critical Care
Prognostic Value of Elevated Troponins in Critical Illness Study: A Pilot Study
Troponins are sensitive and specific markers of cardiac injury. Critically ill patients frequently have elevated troponins. In this population, distinguishing patients with elevated troponins from those with myocardial infarction…
- Conditions
- Troponin, Critical Care, Myocardial Infarction
- Trial name
- PRO-TROPICS (NCT02285686)
- Volunteers
- 251 people
- Sponsor
- McMaster University
Myocardial Infarction, Acute
Prognostic Value of Surem TRAF3IP2 Level in Patients With Acute Myocardial Infarction
To evaluate the prognostic value of surem TRAF3IP2 levels in patients with acute myocardial infarction
- Trial name
- NCT06038994
- Testing
- No intervention
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Nanjing Medical University
Acute Coronary Syndrome
Assessing the Efficacy of CardiOGoniometry (CGM) to Localise the Culprit Vessel in Mixed Vessel Disease Non-ST elevatIon Myocardial infarcTION (NSTEMI)
This study aims to test the hypothesis that cardiogoniometry (CGM) is helpful to identify the site of the culprit vessel in patients with NSTEMI in comparison to 12-lead ECG.
- Trial name
- COGNITION (NCT02803931)
- Testing
- Cardiogoniometry, 12-lead ECG
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Hull University Teaching Hospitals NHS Trust
Acute Myocardial Infarction
Phase II Clinical Trial to Evaluate the Benefits of Postconditioning in ST-Elevation Myocardial Infarction (STEMI)
This study will evaluate change in heart muscle function from baseline to three months and twelve months in participants who present with a heart attack and a completely occluded coronary artery.
- Trial name
- NCT01324453
- Testing
- Post Conditioning + Primary PCI, Standard Primary PCI
- Where
- United States
- Volunteers
- 103 people
- Sponsor
- Minneapolis Heart Institute Foundation
Coronary Artery Disease
The Peri-OPerative COlchicine to Reduce Negative Events (POPCORN) Trial
Heart disease remains the leading cause of death in Veterans. Inflammation in the arteries of the heart may increase the risk of cardiac death.
- Trial name
- POPCORN (NCT05618353)
- Testing
- Colchicine
- Where
- 9 sites in United States
- Volunteers
- 700 people
- Sponsor
- VA Office of Research and Development
Pain, Anxiety
The Effect of Cold Spray Applied Before Local Anaesthesia
Coronary angiography is a reliable and valid method used in the diagnosis of Coronary Artery Disease (CAD). Coronary angiography is defined as the process of obtaining cineangiographic images by administering radio-opaque…
- Conditions
- Pain, Anxiety, Coronary Artery Disease
- Trial name
- EffectofCold (NCT06035237)
- Testing
- Cold Spray
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ozkan Sir
Type 2 Diabetes, Coronary Artery Disease (CAD)
Effect of a Low Advanced Glycation End Products Diet of Patients With Type 2 Diabetes Mellitus
The present study showed that a reduction of approximately 56% in CML consumption promoted a 30% reduction in this blood biomarker.
- Trial name
- NCT07303842
- Testing
- a low-CML diet, Control
- Where
- Brazil
- Volunteers
- 36 people
- Sponsor
- InCor Heart Institute
Coronary Arteriosclerosis
Dietary Nitrate and Nitrite to Increase Nitric Oxide in Patients With Coronary Artery Disease
This study will determine whether dietary nitrates and nitrites can produce nitric oxide in the body and dilate blood vessels in patients with coronary artery disease.
- Trial name
- NCT00069654
- Testing
- Forearm blood flow study, Brachial artery reactivity study, Treadmill exercise test
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Coronary Artery Disease
Effects of Theraband Resistance Training on Muscle Strength in Coronary Artery Diseases
To compare the effects of Theraband Resistance Training with Conventional Resistance Training on muscle strength in coronary artery diseases
- Trial name
- NCT06437756
- Testing
- Theraband resistance training, Conventional Resistance Training
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
Coronary Artery Disease, Chronic Total Occlusion
CTO-PCI in Heart Failure Patients
The study investigates wheather CTO-PCI improves survival and heart failure related rehospitalization compared to optimal medical therapy (OMT).
- Conditions
- Coronary Artery Disease, Chronic Total Occlusion, Heart Failure
- Trial name
- CTO-HF (NCT05632653)
- Testing
- CTO-PCI
- Volunteers
- 783 people
- Sponsor
- Universitätsmedizin Mannheim
Coronary Artery Disease, Hyperlipidemias
Optimal Attained LDL-Cholesterol Levels in Patients Who Achieved ≥50% LDL Reduction After PCI
For the management of low-density lipoprotein-cholesterol (LDL-C), some guidelines recommend initial statin treatment with high-intensity statins to achieve at least a 50% reduction in LDL-C levels.
- Trial name
- Lipid-PCI (NCT06338956)
- Testing
- LDL reduction therapy
- Where
- South Korea
- Volunteers
- 135,877 people
- Sponsor
- Samsung Medical Center
Coronary Heart Disease
China PEACE-Prospective PCI Study
Coronary heart disease (CHD) pose a serious health threaten to population. PCI, as a well-proved and booming measure in CHD management, is invasive and of high cost, however the knowledge about the real-life PCI use in China is…
- Trial name
- NCT01624922
- Where
- China
- Volunteers
- 5,185 people
- Sponsor
- China National Center for Cardiovascular Diseases
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