Clinical trials: Myocardial Perfusion Imaging
Ischemic Heart Disease
Myocardial Perfusion Imaging by 15O-H2O PET/CT
The trial will include 5000 patients with evident or suspected ischemic heart disease refered to Department of Nuclear Medicine \& PET Centre, Aarhus University Hospital, for perfusion imaging by 15O-H2O PET/CT scan of the heart…
- Trial name
- NCT04451551
- Where
- Denmark
- Volunteers
- 5,000 people
- Sponsor
- University of Aarhus
NonST Elevation Myocardial Infarction
FAMOUS-NSTEMI MRI Sub-Study
BACKGROUND: Non-ST-segment elevation myocardial infarction (NSTEMI) is the commonest type of acute coronary syndrome (ACS) and has a poor long-term prognosis.
- Trial name
- NCT02073422
- Testing
- Fractional flow reserve, Magnetic resonance imaging
- Where
- United Kingdom
- Volunteers
- 106 people
- Sponsor
- NHS National Waiting Times Centre Board
Coronary Artery Disease
Prognostic Value of Cardial Stress Perfusion Imaging
Stress myocardial perfusion scintigraphy is a reference examination for the detection and monitoring of coronary patients, and this examination has already been the subject of multiple validation studies, including for the…
- Trial name
- PROSPERCARS (NCT04564794)
- Where
- France
- Volunteers
- 11,952 people
- Sponsor
- Central Hospital, Nancy, France
Coronary Artery Disease, Type 1 Diabetes Mellitus
Regadenoson Blood Flow in Type 1 Diabetes (RABIT1D)
Cardiovascular disease (CVD) remains the major cause of mortality and morbidity in both type 1 (T1D) and type 2 (T2D) diabetes patients; modifications of traditional CVD risk factors have had a limited impact.
- Trial name
- RABIT1D (NCT01019486)
- Testing
- Regadenoson myocardial perfusion imaging, Regadenoson MRI myocardial blood flow
- Where
- 4 sites in United States
- Volunteers
- 26 people
- Sponsor
- University of Colorado, Denver
Coronary Artery Disease (CAD)
An International Study to Evaluate Diagnostic Efficacy of Flurpiridaz (18F) Injection PET MPI in the Detection of Coronary Artery Disease (CAD)
This is a Phase 3, prospective, open-label, international, multicentre study of Flurpiridaz (18F) Injection for PET MPI in patients referred for ICA because of suspected CAD.
- Trial name
- NCT03354273
- Testing
- PET MPI, SPECT MPI, Pharmacological stress agents
- Where
- 53 sites in United States, Canada and 5 more
- Volunteers
- 730 people
- Sponsor
- GE Healthcare
Breast Cancer
Screening in Myocardial Perfusion Patients
To expand the understanding of the uptake and distribution of Tc-99m sestamibi in the breast in a normal female population undergoing myocardial perfusion imaging using Molecular Breast Imaging (MBI).
- Trial name
- NCT00943241
- Where
- United States
- Volunteers
- 322 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Chest Pain, Coronary Artery Disease
Study of Value of Cardiac PET Scans With or Without CT Angiography and/or Measurement of Coronary Flow Reserve
How does PET myocardial perfusion imaging involving CT angiography and measurement of coronary flow reserve affect patient care.
- Trial name
- NCT00669968
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Kettering Health Network
Heart Failure
The Role of Nuclear Imaging in Heart Failure
Heart failure is a clinical syndrome of exercise intolerance and/or congestion. The potential roles of myocardial perfusion and metabolic abnormalities in subjects with cardiovascular risks, metabolic disease and heart failure…
- Trial name
- NCT02697669
- Testing
- 18F-FDG PET
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- Far Eastern Memorial Hospital
Myocardial Ischemia
Stress CMR Perfusion Imaging in the United States (SPINS) Study
Numerous single-center studies have indicated gadolinium-enhanced stress CMR perfusion imaging has excellent diagnostic accuracy for coronary artery disease and negative clinical event rates, with its diagnostic accuracy…
- Trial name
- SPINS (NCT03192891)
- Testing
- Stress cardiac magnetic resonance (CMR) perfusion imaging
- Where
- 13 sites in United States
- Volunteers
- 2,349 people
- Sponsor
- Society for Cardiovascular Magnetic Resonance
Coronary Artery Disease
RAdiolabeled Perfusion to Identify Coronary Artery Disease Using WAter To Evaluate Responses of Myocardial FLOW (RAPID-WATER-FLOW)
This a Phase 3, prospective, open-label, multicenter study of [15-O]-H2O injection for PET imaging of subjects with suspected CAD.
- Trial name
- NCT05134012
- Testing
- [O-15]-Water PET Myocardial Perfusion Imaging (MPI)
- Where
- 13 sites in United States, Canada and 4 more
- Volunteers
- 215 people
- Sponsor
- MedTrace Pharma A/S
Type 2 Diabetes
Myocardial Perfusion in Type 2 Diabetes
The investigators aimed to evaluate microvascular circulation with novel method: real-time myocardial contrast echocardiography in patients with type 2 diabetes and normal coronary arteries.
- Trial name
- NCT01043965
- Testing
- Metformin
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Coronary Artery Disease
Advanced Cardiac Magnetic Resonance Imaging for Assessment of Obstructive Coronary Artery Disease: ADVOCATE-CMR
Stress perfusion cardiovascular magnetic resonance (CMR) imaging is an established non-invasive imaging test for detection of obstructive coronary artery disease (CAD).
- Trial name
- ADVOCATE-CMR (NCT06419894)
- Volunteers
- 182 people
- Sponsor
- Amsterdam UMC, location VUmc