Clinical trials: Myocarditis Acute
Myocarditis Acute
MYTHS - MYocarditis THerapy With Steroids
This is a phase III, multi-center international, single blind randomized controlled trial to test the efficacy of pulsed intravenous (IV) methylprednisolone versus standard therapy on top of maximal support in patients with Acute…
- Trial name
- MYTHS (NCT05150704)
- Testing
- Methylprednisolone, saline solution
- Where
- 49 sites in United States, Austria and 7 more
- Volunteers
- 288 people
- Sponsor
- Niguarda Hospital
Myocarditis Acute, Myocardial Inflammation
CMR Evaluation of Myocardial Inflammation Persistence After Acute Myocarditis: Prognostic Relevance
Patients with acute myocarditis (AM) usually experience spontaneous healing, but a considerable percentage of them evolve towards chronic long-term cardiac impairment.
- Trial name
- MIAMI (NCT03525639)
- Testing
- Cardiac Magnetic Resonance
- Where
- 3 sites in Italy
- Volunteers
- 80 people
- Sponsor
- Antonio Esposito
Acute Myocarditis
The Role of Levosimendan as Inotropic Agent in Acute Aluminum Phosphide-induced Cardiotoxicity
To evaluate the potential role of levosimendan as an inotropic agent in aluminum phosphide-induced cardiotoxicity
- Trial name
- NCT06478667
- Testing
- levosemindan
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Acute Myocarditis
MYTHS-MR Trial (MYocarditis THerapy With Steroids in Patients With Mildly Reduced Ejection Fraction)
The goal of this clinical trial is to demonstrate the efficacy of pulsed intravenous methylprednisolone in a single-blind randomized controlled trial versus standard therapy in patients with acute myocarditis and a mildly reduced…
- Trial name
- MYTHS-MR (NCT05974462)
- Testing
- Methylprednisolone 125 MG, IV saline solution 0.9%
- Where
- 19 sites in Belgium, Italy and 2 more
- Volunteers
- 174 people
- Sponsor
- University Hospital, Antwerp
COVID, Acute Coronary Syndrome
Cardiovascular Complications and COVID-19 (CovCardioVasc-Study)
Patients with COVID-19 in the Intensive Care Unit (ICU) or hospitalized with severe form have a poor prognosis (almost 30% rate of death).
- Conditions
- COVID, Acute Coronary Syndrome, Myocardial Infarction, Myocarditis
- Trial name
- CovCardioVasc (NCT04335162)
- Where
- 8 sites in France
- Volunteers
- 198 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Myocarditis Acute, Inflammatory Cardiomyopathy
Creation of a National Multicenter Platform for the Study of Inflammatory Myocardial Disease: Pre-MYO Cohort
The objectives of this project are: 1) to comprehensively characterize a large national cohort of patients with suspected myocarditis, their clinical phenotype, care management, blood and imaging biomarkers, epidemiological…
- Trial name
- PREMYO (NCT06898762)
- Testing
- characterization of a large national cohort of patients with suspected myocarditis or inflammatory cardiomyopathy.
- Where
- Spain
- Volunteers
- 3,000 people
- Sponsor
- Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia
Myocarditis Acute
Pulse Corticosteroids Or/and Immunoglobulins to Treat Fulminant Myocarditis
Fulminant myocarditis (FM) is the most severe manifestation of acute myocarditis, an acute inflammatory myocardial disease most often triggered by viral infections.
- Trial name
- CORIUM (NCT06896253)
- Testing
- Pulse bolus corticosteroids, Pulse bolus corticosteroids and IVIG, Pulse bolus corticosteroids (G5%) and IVIG (G5 %)
- Volunteers
- 120 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cardiac Imaging Techniques, Cardiac Imaging
Role of Spectral CT in the Diagnosis of Myocarditis/MINOCA in Patients Undergoing cardioCT Investigations for Acute Chest Pain
It is a spontaneous, observational cross-sectional and single-center imaging (CT and MRI) study, coupled with clinical-laboratory data.
- Conditions
- Cardiac Imaging Techniques, Cardiac Imaging, Myocardial Disease, Myocarditis Acute
- Trial name
- NCT06804278
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Acute Myocarditis, Cardiac Sarcoidosis
Somatostatin Receptor Imaging in Acute Myocarditis and Cardiac Sarcoidosis
This prospective imaging study investigates the diagnostic ability of Gallium-68 DOTA-TOC (68Ga-DOTA-TOC) positron emission tomography/computed tomography (PET/CT) in the clinical work-up of patients with 1) clinically suspected…
- Trial name
- NCT04206163
- Testing
- 68Ga-DOTA-TOC PET/CT, Blood sample
- Where
- Sweden
- Volunteers
- 78 people
- Sponsor
- Vastra Gotaland Region
Acute Myocarditis
Corticoid Therapy in Acute Myocarditis
Refer to the "Detailed Description" section.
- Trial name
- COTAM (NCT06522100)
- Testing
- Intravenous administration of Methylprednisolone, Oral Prednisone
- Volunteers
- 420 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Myocarditis; Acute or Subacute, Takotsubo Cardiomyopathy
Characterization of Acute Myocardial Damage With Spectral Computed Tomography. (CADAMI-SPECTRAL)
Clinical management of patients with chest pain and elevation of biomarkers of myocardial injury require an accurate diagnosis. Until now, cardiac magnetic resonance imaging (cMRI) is the gold standard for the diagnosis among…
- Conditions
- Myocarditis; Acute or Subacute, Takotsubo Cardiomyopathy, Infarction, Myocardial, Myocardial Injury
- Trial name
- CADAMI (NCT06506071)
- Testing
- Spectral CT
- Where
- Spain
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Salamanca University Hospital
Myocardial Infarction With Non-Obstructive Coronary Artery, Myocarditis Acute
Comparison of Free-breathing 3D Quantitative Perfusion in Patients With MINOCA and MINOCA-mimics
This clinical study examines patients presenting with acute myocardial infarction and no significant coronary artery disease on coronary angiography (MINOCA) and patients with MINOCA-mimics with advanced CMR.
- Conditions
- Myocardial Infarction With Non-Obstructive Coronary Artery, Myocarditis Acute, Takotsubo Cardiomyopathy, Spontaneous Coronary Artery Dissection
- Trial name
- COPE-CMR (NCT06323811)
- Testing
- CMR
- Where
- Switzerland
- Volunteers
- 75 people
- Sponsor
- University of Zurich
Acute Myocarditis
Anakinra Versus Placebo for the Treatment of Acute MyocarditIS
There is no specific treatment of acute myocarditis, especially during the inflammatory period. Interleukin (IL) is specifically involved during this period and play a role in myocardial oedema.
- Trial name
- ARAMIS (NCT03018834)
- Testing
- ANAKINRA 100 mg/daily subcutaneously
- Where
- 2 sites in France
- Volunteers
- 120 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Myocarditis, Myocarditis Acute
MYocarditis and/or Pericarditis Following mRNA COVID-19 VACCination National Surveillance Study
Myocarditis is inflammation of the heart muscle. Pericarditis is inflammation of the lining surrounding the heart muscle. Symptoms of these conditions can include pain in the chest and rapid or irregular heartbeat.
- Conditions
- Myocarditis, Myocarditis Acute, Pericarditis, Pericarditis Acute
- Trial name
- MYCOVACC (NCT06103123)
- Testing
- Stand of care ECG, Holter, MRI, ECHO, Quality of life questionnaire, Baseline Quality of Life questionnaire
- Where
- Canada
- Volunteers
- 500 people
- Sponsor
- Cardiology Research UBC
Acute Myocarditis
Hospital Registry of Acute Myocarditis: Evolution of the Proportion of Positive SARS-COV-2 (COVID19) Cases
To date, the effects of SARS-Cov-2 (Covid-19) on the myocardium and the role it plays in the evolution towards an acute myocarditis are badly understood.
- Trial name
- MYOCOVID (NCT04375748)
- Testing
- Performing routine care (clinical and paraclinical tests), Examinations for the research:
- Where
- 65 sites in France, Martinique and 2 more
- Volunteers
- 756 people
- Sponsor
- University Hospital, Toulouse
Myocarditis Acute
Multicenter Retrospective Observational Study of Acute Myocarditis in Korea
In this study, the investigators analyze the clinical characteristics and prognosis of patients with acute myocarditis in South Korea
- Trial name
- NCT05933902
- Where
- South Korea
- Volunteers
- 841 people
- Sponsor
- Samsung Medical Center
Myocarditis Acute
Positron Emission Tomography for the Diagnosis of Immune Checkpoint Inhibitor-Related Myocarditis
This study evaluates positron emission tomography for the diagnosis of immune checkpoint inhibitor-related myocarditis. Immune checkpoint inhibitors have shown promising results in various malignancies however, several immune…
- Trial name
- NCT05062395
- Testing
- Computed Tomography, Fludeoxyglucose F-18, Low Carbohydrate High Fat Diet
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- M.D. Anderson Cancer Center
Severe Acute Respiratory Syndrome-related Coronavirus, Renal Dialysis
Medicine-induced Cardiac Hemodialysis on COVID-19
The clinical trial studies the human pathogen of SARS-CoV-2, with a specificity in the circulating Spike 2 protein in the human system.
- Conditions
- Severe Acute Respiratory Syndrome-related Coronavirus, Renal Dialysis, Vaccines, Myocarditis Allergic
- Trial name
- NCT05711810
- Testing
- Nifedipine 30 MG, Kangzhu BPCB0A-3A, Low Mobility
- Where
- China
- Volunteers
- 1 people
- Sponsor
- Yang I. Pachankis
Myocarditis Acute, Ventricular Arrythmia
Evaluation of Long-term Incidence of Ventricular Arrhythmias in Patients With Acute Myocarditis
Myocarditis is an inflammatory disease of the heart muscle which is mostly caused by viruses, bacteria, parasites, toxic substances/drugs or by primary autoimmune mechanisms.
- Trial name
- AIM-ICD (NCT04264455)
- Testing
- Biomonitor, Life Vest, Implantable Cardioverter-Defibrillator (ICD)
- Where
- Germany
- Volunteers
- 34 people
- Sponsor
- Wuerzburg University Hospital
Patients With Suspected Acute Myocarditis
Evaluation of Spectral Cardiac CT for the Diagnosis of Acute Myocarditis
Spectral cardiac CT scan performed in an emergency setting in patients with suspected acute myocarditis and presenting one selves with an acute chest pain, allows the non-invasive assessment of both the coronary arteries and the…
- Trial name
- MYOCARDITESCAN (NCT02905721)
- Testing
- Spectral cardiac CT scan
- Where
- France
- Volunteers
- 136 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris