Clinical trials: Myocarditis Acute
Acute Myocarditis, Cardiac Sarcoidosis
Somatostatin Receptor Imaging in Acute Myocarditis and Cardiac Sarcoidosis
This prospective imaging study investigates the diagnostic ability of Gallium-68 DOTA-TOC (68Ga-DOTA-TOC) positron emission tomography/computed tomography (PET/CT) in the clinical work-up of patients with 1) clinically suspected…
- Trial name
- NCT04206163
- Testing
- 68Ga-DOTA-TOC PET/CT, Blood sample
- Where
- Sweden
- Volunteers
- 78 people
- Sponsor
- Vastra Gotaland Region
Myocarditis Acute
French Registry of CMR Late Gadolinium Enhancement in Myocarditis
Acute myocarditis is a major cause of death in young adults and carries substantial morbidity, including a significant risk of progression to dilated cardiomyopathy.
- Trial name
- MYOCARDITI-LGE (NCT07394543)
- Volunteers
- 5,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Myocarditis Acute
Non-Steroidal Anti-Inflammatory Drugs in Acute Myocarditis
Prospective, randomized, multicenter, open-label clinical trial to evaluate the safety and efficacy of a 3-week ibuprofen tapering regimen compared to conventional analgesic treatment (acetaminophen) in patients with acute…
- Trial name
- INFLAMA (NCT06686862)
- Testing
- ibuprofen
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III
Cardiogenic Shock, Acute Myocardial Infarction
Oxidant-antioxidant Activity, Free Radicle Activity, Immune Response and Biomarkers in Extracorporeal Membrane Oxygenation (ECMO) Patients
We would like to investigate novel diagnostic methods or biomarkers to early predict the success of ECMO therapy for cardiogenic shock patients during the early stage after ECMO treatment.
- Conditions
- Cardiogenic Shock, Acute Myocardial Infarction, Myocarditis, Cardiomyopathy
- Trial name
- ECMO (NCT01089036)
- Where
- 2 sites in Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
PEDIATRIC ACUTE MYOCARDITIS
ANAKINRA IN THE TREATMENT OF PEDIATRIC ACUTE MYOCARDITIS
Double blind RCT aiming to compare the efficacy of Anakinra vs placebo, on top of the standard of care, on restoration of myocardial function at 3 days following treatment initiation, in children admitted for acute myocarditis in…
- Trial name
- ANAPEM (NCT07371689)
- Testing
- Anakinra, KINERET®
- Where
- France
- Volunteers
- 110 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Coronary Artery Disease, Arrhythmias, Cardiac
Prognosis Prediction System of Patients With Cardiovascular and Cerebrovascular Diseases Based on Multi-omics
The etiology and specific pathogenesis of many cardiovascular diseases such as coronary atherosclerosis, cardiomyopathy, atrial fibrillation, and stroke are still unclear.
- Conditions
- Coronary Artery Disease, Arrhythmias, Cardiac, Heart Valve Diseases, Aortic Dissection
- Trial name
- PROSPECT (NCT06001073)
- Testing
- Observational; No Interventions were given.
- Where
- China
- Volunteers
- 25,000 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Myocarditis
International Myocarditis Registry
Myocarditis is an inflammatory heart disease primarily of viral origin that can lead to heart failure and death. Despite an unfavorable long-term outcome and mortality rate as high as 50%, classification, diagnosis, and treatment…
- Trial name
- mmr (NCT01307735)
- Where
- Canada
- Volunteers
- 78 people
- Sponsor
- Libin Cardiovascular Institute of Alberta
Myocarditis, Myocarditis Acute
Outcome of Clinical Phenotypes of Pediatric Myocarditis at Assiut University Children Hospital
This study aims to investigate the clinical phenotypes, management approaches, and outcomes of myocarditis in children admitted to Assiut University Children's Hospital.
- Trial name
- PED-MYO (NCT07175948)
- Testing
- Standard Medical Therapy
- Volunteers
- 100 people
- Sponsor
- Assiut University
Myocarditis
Acute Myocarditis Registry With Prognostic, Histologic, Immunologic, Biological, Imaging and Clinical Assessment
The AMPHIBIA study is an observational ambispective and prospective cohort that aim to describe the histologic, immunologic, biological, imaging, genetic and clinical characteristics of the patients hospitalized for an acute…
- Trial name
- AMPHIBIA (NCT04844151)
- Where
- France
- Volunteers
- 1,400 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Acute Myocarditis
The Role of Levosimendan as Inotropic Agent in Acute Aluminum Phosphide-induced Cardiotoxicity
To evaluate the potential role of levosimendan as an inotropic agent in aluminum phosphide-induced cardiotoxicity
- Trial name
- NCT06478667
- Testing
- levosemindan
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Myocarditis; Acute or Subacute, Takotsubo Cardiomyopathy
Characterization of Acute Myocardial Damage With Spectral Computed Tomography. (CADAMI-SPECTRAL)
Clinical management of patients with chest pain and elevation of biomarkers of myocardial injury require an accurate diagnosis. Until now, cardiac magnetic resonance imaging (cMRI) is the gold standard for the diagnosis among…
- Conditions
- Myocarditis; Acute or Subacute, Takotsubo Cardiomyopathy, Infarction, Myocardial, Myocardial Injury
- Trial name
- CADAMI (NCT06506071)
- Testing
- Spectral CT
- Where
- Spain
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Salamanca University Hospital
Patients With Suspected Acute Myocarditis
Evaluation of Spectral Cardiac CT for the Diagnosis of Acute Myocarditis
Spectral cardiac CT scan performed in an emergency setting in patients with suspected acute myocarditis and presenting one selves with an acute chest pain, allows the non-invasive assessment of both the coronary arteries and the…
- Trial name
- MYOCARDITESCAN (NCT02905721)
- Testing
- Spectral cardiac CT scan
- Where
- France
- Volunteers
- 136 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cardiogenic Shock, Myocardial Infarction (MI)
BEAT-SHOCK Registry
This regulation defines the purpose, the operational processes, and the organization of the registry BEAT-SHOCK (Basel Evaluation of Acute Therapy in cardiogenic SHOCK).
- Conditions
- Cardiogenic Shock, Myocardial Infarction (MI), Fulminant Myocarditis, Acute Decompensated Heart Failure
- Trial name
- BEAT-SHOCK (NCT07643610)
- Testing
- no internvention
- Where
- Switzerland
- Volunteers
- 8,000 people
- Sponsor
- University Hospital, Basel, Switzerland
Myocarditis
Clinical, Morphological and Functional Aspects in Myocarditis.
Cardiac magnetic resonance (CMR) is accurate to identify acute myocardial damage (edema, hyperemia, and/or fibrosis) due to acute myocarditis (AM).
- Trial name
- NCT04217876
- Testing
- post-processing analysis of cardiac imaging (strain echocardiography)
- Where
- 4 sites in Italy
- Volunteers
- 200 people
- Sponsor
- University of Messina
Myocarditis Acute
MCE Molecular Imaging for Myocarditis
Inflammation of the heart (myocarditis) is a serious condition that can cause heart failure, abnormal heart rhythms, cardiac arrest, and death. Rapid diagnosis of this condition is key to reversing it.
- Trial name
- NCT07538544
- Testing
- Myocardial contrast echocardiography molecular imaging for inflammation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Virginia
Myocarditis Acute, Ventricular Arrythmia
Evaluation of Long-term Incidence of Ventricular Arrhythmias in Patients With Acute Myocarditis
Myocarditis is an inflammatory disease of the heart muscle which is mostly caused by viruses, bacteria, parasites, toxic substances/drugs or by primary autoimmune mechanisms.
- Trial name
- AIM-ICD (NCT04264455)
- Testing
- Biomonitor, Life Vest, Implantable Cardioverter-Defibrillator (ICD)
- Where
- Germany
- Volunteers
- 34 people
- Sponsor
- Wuerzburg University Hospital
Myocarditis Acute, Ventricular Arrythmia
Ventricular Arrhythmia After Myocarditis in Sportsman
The study aims to assess the prevalence of ventricular rhythmic disorder after an acute myocarditis in sportsmen. 50 patients with acute myocarditis, confirmed by MRI, will be assessed by ECG Holter and Treadmill stress test…
- Trial name
- ARYMYS (NCT03842592)
- Testing
- Treadmill Stress test
- Where
- 4 sites in France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Angers
Acute Myocarditis
Hospital Registry of Acute Myocarditis: Evolution of the Proportion of Positive SARS-COV-2 (COVID19) Cases
To date, the effects of SARS-Cov-2 (Covid-19) on the myocardium and the role it plays in the evolution towards an acute myocarditis are badly understood.
- Trial name
- MYOCOVID (NCT04375748)
- Testing
- Performing routine care (clinical and paraclinical tests), Examinations for the research:
- Where
- 65 sites in France, Martinique and 2 more
- Volunteers
- 756 people
- Sponsor
- University Hospital, Toulouse
Myocarditis
Cardiac Magnetic Resonance in Acute Myocarditis
Cardiac magnetic resonance (MR) is an established noninvasive diagnostic tool for detection of acute myocarditis. Diagnosis of myocarditis at 1.5T is currently made with the help of the Lake Louise Criteria (two of three criteria…
- Trial name
- NCT02299856
- Testing
- Cardiac magnetic resonance scan
- Where
- Germany
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bonn
Myocarditis Acute
Positron Emission Tomography for the Diagnosis of Immune Checkpoint Inhibitor-Related Myocarditis
This study evaluates positron emission tomography for the diagnosis of immune checkpoint inhibitor-related myocarditis. Immune checkpoint inhibitors have shown promising results in various malignancies however, several immune…
- Trial name
- NCT05062395
- Testing
- Computed Tomography, Fludeoxyglucose F-18, Low Carbohydrate High Fat Diet
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- M.D. Anderson Cancer Center