Clinical trials: Myopathies
Glycogen Storage Disease, GSD Type 0A
Rare Glycogen Storage Diseases Natural History Study
The purpose of this study is to collect and study key medical data about several ultra-rare GSDs (Glycogen Storage Diseases) including, but not limited to, GSD types 0a, 0b, VII, X, XII, XIII, XV, PRKAG2 syndrome and Danon…
- Conditions
- Glycogen Storage Disease, GSD Type 0A, GSD Type 0B, GSD VII
- Trial name
- NCT06795152
- Testing
- No intervention
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Duke University
Muscle Weakness
Randomized Controlled Trial Comparing Traditional Pelvic Floor Rehabilitation to Pilates in Increasing Pelvic Muscles Strength.
The objective of this randomized controlled trial is to determine whether a standardized Pilates exercise program can effectively strengthen pelvic floor muscles when compared with conventional pelvic muscle rehabilitation.
- Trial name
- NCT00549458
- Testing
- Pilates, Pelvic muscle rehabilitation therapy
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Atlantic Health System
Musculoskeletal Pain
Impact of Exercises and Chair Massage on Musculoskeletal Pain of Young Musicians
The study is tested the idea of two forms of musculoskeletal pain prophylaxis (chair massage and an original set of exercises) among musicians.
- Trial name
- NCT04366843
- Testing
- chair massage, the exercise program
- Where
- Poland
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Józef Piłsudski University of Physical Education
Fibromyalgia, Physiotherapy
Effectiveness of the Strain Counterstrain Technique in Women With Fibromyalgia Syndrome
This study evaluates whether strain counterstrain therapy affects pain, fatigue, psychological status, and quality of life in women diagnosed with fibromyalgia.
- Conditions
- Fibromyalgia, Physiotherapy, Pain, Strain Counterstrain Technique
- Trial name
- NCT07421609
- Testing
- Conservative Physiotherapy Program, Strain Counterstrain Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people
- Sponsor
- Hasan Kalyoncu University
Fibromyalgia, Aromatherapy
The Effect of Peppermint Oil Aromatherapy on Pain, Functional Capacity and Cost in Fibromyalgia Patients
This study was designed to evaluate the effect of topically applied peppermint oil (Mentha × piperita) on chronic pain and functional capacity experienced by fibromyalgia patients, as well as its cost-effectiveness.
- Conditions
- Fibromyalgia, Aromatherapy, Cost
- Trial name
- NCT07326163
- Testing
- Peppermint Oil, sweet almond oil, Duloxetine
- Where
- Turkey (Türkiye)
- Volunteers
- 175 people
- Sponsor
- Bilecik Seyh Edebali Universitesi
Musculoskeletal Pain, Physical Function
The Effect of a Resistance Training Program in Healthcare Workers on Pain, Workability and Physical Function.
The prevalence and consequences of musculoskeletal pain is considerable among healthcare workers, allegedly due to high physical work demands of healthcare work.
- Conditions
- Musculoskeletal Pain, Physical Function, Work Ability
- Trial name
- NCT03501147
- Testing
- Resistance training
- Where
- Spain
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Tendinopathy
Clinical Predictors of Extracorporal Shockwave Therapy Efficacy in Patients Presenting With Lateral Hip Pain
This pragmatic clinical trial is considering the variable response to treatment outcome of individuals with Greater Trochanteric Pain Syndrome (GTPS).
- Trial name
- NCT04058509
- Testing
- Focused shockwave therapy
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Aalborg University Hospital
Articular; Rigid
Physiotherapeutic Case Studies in Frozen Shoulder Pathology
The stiff shoulder presents symptoms such as pain, loss of mobility and strength, being more common the idiopathic origin associated to the female gender.
- Trial name
- CH-Case (NCT05175586)
- Testing
- First data analysis, Second data analysis, database
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- GEMA LEÓN BRAVO
Fibromyalgia, Chronic Fatigue Syndrome (CFS)
Effect of Physical Exercise and Neuromodulation on Pain, Sleep and Fatigue in Patients With Fibromyalgia
Fibromyalgia (FMS) is a chronic, multifactorial syndrome characterized by widespread pain, fatigue, and cognitive disturbances. This interventional study evaluates the impact of structured physical training using…
- Trial name
- NCT07242573
- Testing
- Physical Training Program, NESA X-Signal, Conventional Physiotherapy
- Where
- Poland
- Volunteers
- 75 people
- Sponsor
- National Institute of Geriatrics, Rheumatology and Rehabilitation, Poland
Knee Osteoarthritis, Fibromyalgia
Effects of Creatine Supplementation in Women With Knee Osteoarthritis and Fibromyalgia
The purpose of this study is to determine whether creatine associated or not to exercise training can improve physical performance in patients with knee osteoarthritis and fibromyalgia.
- Trial name
- NCT00749983
- Testing
- Creatine supplementation, Dextrose supplementation
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo
Freeman-Burian Syndrome, Freeman-Sheldon Syndrome
Survey Study and Records Review of Treatment Outcomes in Freeman-Sheldon Syndrome
The purpose of this study is to evaluate the difference in diagnosis accuracy, treatment outcomes, patient perspectives, facial function and walking ability, emotional and social health, and respiratory complications between…
- Conditions
- Freeman-Burian Syndrome, Freeman-Sheldon Syndrome, Whistling Face Syndrome, Sheldon-Hall Syndrome
- Trial name
- FINDFSS (NCT05419245)
- Testing
- Guided Health History for Freeman-Burian Syndrome Questionnaire, Freeman-Burian syndrome Semi-Structured Quality of Life Interview, Medical Records Review
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Dufresne, Craig, MD, PC
Dementia Alzheimers
Surface EMG to Measure Paratonia in Dementia
Rationale: A prominent and degenerative motor symptom of dementia is paratonia that heavily affects quality of life. However, paratonia is poorly recognized and the diagnosis yet relies on subjective evaluation by caregivers.
- Trial name
- NCT05606445
- Testing
- Elbow movement
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Muscular Diseases
Differences in Atorvastatin Metabolite Ratios as a Diagnostic Tool in Detecting Atorvastatin Induced Myotoxicity
The primary objective of the study is to investigate whether differences in atorvastatin metabolite ratios might have a positive or negative predictive value in diagnosing atorvastatin muscle toxicity.
- Trial name
- NCT00199745
- Testing
- atorvastatin
- Where
- Norway
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
TMD, TMD/Orofacial Pain
Occlusal Splint Combined With Granisetron Injection for Management of Myofascial Pain Related to Temporomandibular Disorders
The goal of this clinical trial is to evaluate whether a combination of occlusal splint therapy and granisetron injection into the masseter muscle is effective in managing myofascial pain related to temporomandibular disorders…
- Conditions
- TMD, TMD/Orofacial Pain, Temporomandibular Disorder (TMD)
- Trial name
- TMD (NCT07401745)
- Testing
- Granisetron, lidocaine, occlusal splint
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Mansoura University
Periodontal Disease, Chronic Neck Pain
Association Between Periodontal Disease and Chronic Neck Pain
This study investigates whether there is an association between periodontal disease (gum disease) and chronic neck pain and related functional disability.
- Trial name
- NCT07711431
- Where
- Turkey (Türkiye)
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University
Hemodynamic Instability
Study of Ultrasonographic Cava Femoral Ratio in the Critically Ill Patient With Shock
This study aims to describe the ratio of the diameter of inferior vena cava to the common femoral vein measured by ultrasonography in critically ill patients with shock, and to evaluate the potential link between this ratio and…
- Trial name
- ECHO-RCF (NCT02891577)
- Testing
- Ultrasonography
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Muscular Diseases, Spinal Muscular Atrophy
New Imaging Biomarkers for Muscular Diseases - Multispectral Optoacoustic Imaging in Spinal Muscular Atrophy
This study aims to refine the capability of MSOT to characterise muscle tissue and to determine non-invasive, quantitative biomarkers for the disease assessment in patients with spinal muscular atrophy (SMA) using Multispectral…
- Trial name
- MSOT_SMA (NCT04115475)
- Testing
- Multispectral Optoacoustic Tomography (MSOT)
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Incomplete Spinal Cord Injury, Muscular Dystrophy
Evaluating a New Knee-Ankle-Foot Brace to Improve Gait in Children With Movement Disorders
Background: Cerebral palsy (CP) is the most common motor disorder in children. CP often causes crouch gait, an abnormal way of walking. Knee crouch has many causes, so no single device or approach works best for everybody.
- Conditions
- Incomplete Spinal Cord Injury, Muscular Dystrophy, Spina Bifida, Cerebral Palsy
- Trial name
- NCT01961557
- Testing
- EA-KAFO
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Duchenne Muscular Dystrophy
Study of ACE-031 in Subjects With Duchenne Muscular Dystrophy
The purpose of this study is to determine if ACE-031 is safe and well-tolerated in boys with Duchenne Muscular Dystrophy (DMD) and to select the optimal doses of ACE-031 in terms of safety and pharmacodynamic (PD) activity for…
- Trial name
- NCT01099761
- Testing
- ACE-031 0.5 mg/kg q4wk, ACE-031 1.0 mg/kg q2wk
- Where
- 5 sites in Canada
- Volunteers
- 24 people
- Sponsor
- Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ USA
Tennis Elbow
Tissue Flossing in Tennis Elbow Patients
The aim of the present intervention is to determine the effectiveness of the application of tissue flossing in patients with tennis elbow
- Trial name
- FLOSS (NCT03834077)
- Testing
- Tissue flossing
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- University of Jaén
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