Clinical trials: Myopathies
Chronic Pain, Chronic Pelvic Pain Syndrome
BTA vs Baclofen for Pelvic Myofascial Pain Syndrome
The aim of the study is to test the hypothesis that oral taking of baclofen in therapeutic dosage for 60 days is equally effective as injection of botulinum toxin type "A" in the area of trigger points of the pelvic muscles.
- Conditions
- Chronic Pain, Chronic Pelvic Pain Syndrome, Myofascial Pain Syndrome, Myofascial Trigger Point Pain
- Trial name
- BvsB (NCT05617118)
- Testing
- Baclofen 10mg, Botulinum toxin type A
- Where
- Russia
- Volunteers
- 52 people
- Sponsor
- Saint Petersburg State University, Russia
Trigger Finger, Trigger Thumb
Trigger Finger Preference Elicitation Tool
The purpose of this study is to evaluate a patient's level of decisional conflict for their treatment decision regarding their trigger finger, and study if the use of a preference elicitation tool at point of care is able to…
- Conditions
- Trigger Finger, Trigger Thumb, Trigger Digit, Trigger Finger Disorder
- Trial name
- NCT03909490
- Testing
- Preference elicitation tool, handout
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Stanford University
Chronic Fatigue Syndrome, Myalgic Encephalomyelitis
A Trial of Solriamfetol in the Treatment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
This study is an 8-week single center, randomized, double-blind, placebo-controlled, flexible titration trial evaluating the efficacy of solriamfetol in the treatment of fatigue symptoms in adult patients with chronic fatigue…
- Trial name
- NCT04622293
- Testing
- Solriamfetol Oral Tablet [Sunosi]
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Rochester Center for Behavioral Medicine
Myotonic Dystrophy, Congenital, Myotonic Dystrophy, Type 1 (DM1)
Music Intervention for Brain-Heart Disease in Myotonic Dystrophy Type 1 (DM1)
The goal of this interventional study is to demonstrate the feasibility and tolerability of music and movement intervention for children with congenital DM1, while providing indications of its effectiveness in improving brain and…
- Conditions
- Myotonic Dystrophy, Congenital, Myotonic Dystrophy, Type 1 (DM1), Myotonic Dystrophy Type 1, Myotonic Dystrophy Type 1 (DM1)
- Trial name
- NCT06809049
- Testing
- Music and movement education
- Where
- Canada
- Volunteers
- 13 people
- Sponsor
- Hanns Lochmuller
X-linked Myotubular Myopathy
Respiratory Muscle Function in Untreated X-Linked Myotubular Myopathy (XLMTM)
This study is a longitudinal study evaluating the severity and progression of respiratory muscle function in patients with X-Linked Myotubular Myopathy (XLMTM) aged 0-14.
- Trial name
- NCT02453152
- Testing
- History and physical, Tidal breathing, Maximal respiratory pressures
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Florida
Stroke, Spasticity, Muscle
Multiphasic Neuroplasticity Based Training Protocol With Shock Wave Therapy For Post Stroke Spasticity
this study will be conducted to f find the effects of multiphasic neuroplasticity based training protocol with Shock Wave Therapy on Neurophysiological, Morphological and Functional Parameters of Post Stroke Spasticity.
- Trial name
- NCT05405140
- Testing
- Shock wave therapy with multiphasic neuroplasticity based training protocol, Conventional physical therapy
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
The Coordination of Rare Diseases at Sanford (CoRDS) is an international patient registry that serves as a centralized resource for rare disease research.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Tennis Elbow
Influence of Patient Expectations With Lateral Epicondylalgia in Applying Mobilization With Movement
Lateral epicondylalgia affects people of both gender between 1 and 3% of the world population, with up to 15% in the working population reaching an average of 12 weeks off work for this reason.
- Trial name
- NCT02396550
- Testing
- Positive Expectations, Mobilization with movement
- Where
- Spain
- Volunteers
- 66 people
- Sponsor
- University of Alcala
Musculoskeletal Pain, Work Related Stress
Physiatrist Ergonomic Intervention on Work Related Musculoskeletal Pain in Surgeons
The goal of this randomized control trial is to learn if physical therapy coaching and education improves work-related muscle pain in surgeons more than education alone. The main focuses of this study are to: 1.
- Conditions
- Musculoskeletal Pain, Work Related Stress, Quality of Life, Grip
- Trial name
- NCT05946018
- Testing
- Educational video on ergonomics, Verbal physical therapy coaching sessions
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- University of Texas Southwestern Medical Center
Rhabdomyolysis
Extracorporeal Therapy for the Removal of Myoglobin Using the CytoSorb in Patients With Rhabdomyolysis
Prospective, randomized non-blinded, controlled study to assess the feasibility of the CytoSorb as an adjunct to the standard of care in patients with rhabdomyolysis requiring renal replacement therapy.
- Trial name
- NCT02111018
- Testing
- CytoSorb Device, CVVH
- Where
- United States
- Sponsor
- CytoSorbents, Inc
Spasticity, Muscle
Validation of the Spasticity Related Quality of Life Questionnaire
The purpose of the study is to describe the psychometric properties (validity, reliability and responsiveness) of the SQOL-6D instrument in the context of routine clinical treatment of upper limb spasticity.
- Trial name
- SQOL-6D (NCT03442660)
- Testing
- Data collection
- Where
- 8 sites in United Kingdom
- Volunteers
- 104 people
- Sponsor
- Ipsen
Elbow Tendinopathy, Golfer's Elbow
Piezowave for Treatment on Lateral and Medial Elbow Tendinopathies
Within the outpatient rehabilitation clinic, therapists provide therapeutic interventions to treat patients with various tendinopathies, including lateral and medial epicondylosis.
- Conditions
- Elbow Tendinopathy, Golfer's Elbow, Medial Epicondylitis, Lateral Epicondylitis
- Trial name
- NCT04241484
- Testing
- Piezowave 2
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Sepsis, Primary Myopathies
Muscle Force Assessment in the Intensive Care Unit and in Primary Myopathies
The primary aim of the project is to apply the non-invasive stimulated muscle force assessment system to i) intensive care unit patients and ii) patients with primary myopathy or subclinic myopathy (e.g., Duchenne muscular…
- Trial name
- NCT00735384
- Where
- Switzerland
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Fibromyalgia
A Study of Digital Cognitive Behavioural Therapy for Insomnia in Fibromyalgia
The goal of this clinical trial is to investigate the potential benefits of a digital Cognitive Behavioural Therapy for Insomnia (dCBT-I) platform, Sleepio, in individuals suffering from fibromyalgia, a condition commonly…
- Trial name
- Pain-LESS (NCT05962138)
- Testing
- Digital Cognitive Behavioural Therapy for Insomnia
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- University of Oxford
Musculoskeletal Pain, Musculoskeletal Pain Disorder
Exergaming Experience of Older People With Chronic Musculoskeletal Pain
Chronic musculoskeletal pain is debilitating and can lower the quality of life in older people. Therapeutic benefits have been reported from exergaming used as an intervention for rehabilitation or alternative to exercise.
- Trial name
- NCT04029285
- Testing
- Exergaming
- Where
- United Kingdom
- Volunteers
- 54 people
- Sponsor
- Teesside University
Critical Illness Myopathy
NLRP3 Inflammasome and Physical Therapy in ICU-Acquired Weakness
The goal of this clinical trial is to study whether physical therapy can reduce NLRP3 inflammasome activation and muscle atrophy in patients with critical illness myopathy (CIM).
- Trial name
- PT-NLRP3-CIM (NCT07017517)
- Testing
- Motomed Letto® servo-assisted cycling + standard physiotherapy, Standard physiotherapy
- Where
- 3 sites in Chile
- Volunteers
- 24 people
- Sponsor
- University of Chile
SIJ - Sprain of Sacroiliac Joint, Weakness, Muscle
Gluteal Activation With or Without Traction Straight Leg Raise Technique
This study was a Randomized clinical trial conducted to determine the Effects of gluteal activation with or without traction straight leg raise technique among patients of sacroiliac joint syndrome so that in future this study…
- Conditions
- SIJ - Sprain of Sacroiliac Joint, Weakness, Muscle, Tightness of Back Muscles
- Trial name
- NCT04757415
- Testing
- Traction straight leg raise technique for hamstring, Gluteal activation exercises,Hotpack
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
Paraplegia, Spinal Cord Injuries
Natural History of Shoulder Pathology in Manual Wheelchair Users
Over 300,000 people in the United States have spinal cord injuries and many use manual wheelchairs for mobility. Most manual wheelchair users will develop shoulder injuries and pain that greatly affect quality of life and level…
- Conditions
- Paraplegia, Spinal Cord Injuries, Shoulder Pain, Tendinopathy
- Trial name
- NHSSI (NCT02600910)
- Where
- 2 sites in United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Tennis Elbow
Effects of Various Taping Techniques in Lateral Epicondylitis on Functional and Ultrasonographic Outcomes
To compare the early effects of the application of elastic (Kinesio Tape®) and non-elastic (Athletic Tape) taping as part of the conventional physiotherapy of the lateral epicondylitis using the results from ultrasonography and…
- Trial name
- NCT02991560
- Testing
- Strengthening exercises, Intensive Physioytherapy, Kinesio taping
- Volunteers
- 25 people
- Sponsor
- Hacettepe University
Temporomandibular Disorder, Myofascial Pain
Manual Therapy and Splint Therapy in Patients With Temporomandibular Dysfunction
The aim of this study was to compare the efficacy of splint treatment and manual therapy in patients diagnosed with myofascial temporomandibular dysfunction with bruxism.
- Conditions
- Temporomandibular Disorder, Myofascial Pain, Bruxism
- Trial name
- NCT05352438
- Testing
- Manual Therapy Group, Splint Therapy Group
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Turkoglu Dr. Kemal Beyazit State Hospital
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