Clinical trials: Myopia; Refractive Error
Accomodation, Biofeedback Training
Assessment of Accommodation Behavior in Children Under Myopia Control Treatment (Pilot Study)
This study will examine the accommodative behavior in children undergoing myopia control treatments. A subset of children showing reduced accommodation, known to occur in while wearing multifocal soft contact lenses (MFCL) from…
- Conditions
- Accomodation, Biofeedback Training, Myopia
- Trial name
- NCT04807361
- Testing
- Auditory biofeedback traing
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- State University of New York College of Optometry
Myopia, Progressive
Clinical Evaluation of MyoCare in Europe (CEME)
A 2-year prospective, multicenter, randomized controlled, and double-blind clinical trial is used to investigate the efficacy of a new design of ophthalmic lenses to slow the progression of myopia.
- Trial name
- CEME (NCT05919654)
- Testing
- MyoCare, ClearView
- Where
- Spain
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Myopia, Progressive
To Evaluate the Efficacy and Safety of an Defocus Lens in Slowing the Progression of Myopia
To confirm the efficacy of DIMS lenses in controlling myopia progression, we planned a prospective, single-centre, randomised, double-blind, controlled, non-inferiority clinical study.
- Trial name
- NCT06405711
- Testing
- frame lens
- Where
- China
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Myopia
Topography-guided LASIK Surgery
The investigators are analyzing outcomes of topography-guided LASIK surgery in participants with myopia and myopic astigmatism
- Trial name
- NCT03292419
- Testing
- Topography-guided LASIK
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Stanford University
Full Spectrum
A Self-controlled Study of the Effect of Partial Spectral Absence of Visible Light on the Pupil
Previous studies have shown that the spectrum of light influences myopia. LED lights with a partially absent light spectrum increase the risk of myopia progression compared to LEDs with a full spectrum, potentially mediated by…
- Trial name
- NCT06501131
- Testing
- full-spectrum light exposure, specific spectrum absence light exposure
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Myopia
MiSight 1 Day Post-Approval Study for Effectiveness and Visual Symptoms
The purpose of this post-approval study is to confirm the effectiveness of the MiSight 1 Day lens in clinical practices within the US and to assess the stability of the myopia reduction over one-year post-treatment.
- Trial name
- NCT05285553
- Testing
- MiSight 1 Day, Proclear 1 day
- Where
- 30 sites in United States
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia
Evaluation of the Post-LASIK Flap Thickness of the FS200 Femtosecond Laser Flap
The purpose of this study is to document the programmed flap thickness to achieved flap thickness using the FS200 femtosecond laser in performing LASIK procedure.
- Trial name
- NCT01693939
- Testing
- FS200 Femtosecond Laser
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Durrie Vision
Myopia, Refractive Errors
Effect of Repeated Low-Level Red-Light Therapy on Retinal Function and Structure
The purpose of this clinical trial is to evaluate the effect of repeated low-level red-light (RLRL) therapy on the retinal function and structure among myopic teenagers.
- Conditions
- Myopia, Refractive Errors, Eye Diseases, Retina; Change
- Trial name
- NCT05597397
- Testing
- RLRL
- Where
- China
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Myopia
Effects of Autostereoscopic 3D Visual Training on Binocular Vision Function of Myopes
This study intends to conduct a relatively comprehensive binocular visual function examination and follow-up on two groups of myopic subjects, one receiving autostereoscopic 3D vision training and the other receiving 2D vision…
- Trial name
- NCT06266910
- Testing
- Visual training video
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Myopia, Hyperopia
One-month Clinical Evaluation of Oté Sensation Multi-Purpose Solution Care System
The purpose of this study is to evaluate the clinical performance of the contact lens care product Oté Sensation in a representative population of soft contact lens wearers.
- Trial name
- NCT03278223
- Testing
- Test solution, Control solution
- Where
- 11 sites in United States, United Kingdom
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- OTE North America
Myopia, Mental Health
A Study of the Impact of Digital Intervention on Parents/primary Caregivers' Myopia Prevention and Control Health Literacy on Preschoolers' Myopia and Physical and Mental Health
The study is a Randomized controlled trial based on digital interventions, involving pre-school children and their parents or major caregivers.
- Conditions
- Myopia, Mental Health, Obesity
- Trial name
- NCT06620250
- Testing
- Digital Prevention and control of myopia
- Volunteers
- 882 people, healthy volunteers welcome
- Sponsor
- Fangbiao Tao
Myopia
Identification of Genomic Loci Determining Susceptibility to the Development of High Myopia
Compelling evidence of genetic components in high myopia has been put forward by several studies. Twin cohorts, familial linkage studies and population studies has described at least 10 loci containing genes involved in the…
- Trial name
- ASSOMYP (NCT02583620)
- Testing
- blood sample
- Where
- 4 sites in France
- Volunteers
- 553 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Myopia
Pilot Study to Assess the Efficacy of Short Exposure to Defocus to Slow the Progression of Myopia in Children
The objective of this pilot study is to establish whether brief periods of high levels of acutely imposed myopic defocus can be used to slow the progression of myopia in children, as measured by changes in spherical equivalent…
- Trial name
- NCT00400140
- Testing
- Hyperopic lens
- Where
- Singapore
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Singapore National Eye Centre
Myopia
Assessment of Measurement Variability Across Automated Biometry Devices
This is a non-interventional prospective, comparative study of white-to-white, corneal thickness, and anterior chamber depth measurements as taken on the Orbscan II compared to the IOL Master 700 (Zeiss), IOL Master 500 (Zeiss)…
- Trial name
- NCT06045325
- Testing
- Orbscan II, IOL Master 700, IOL Master 500
- Where
- United States
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Berkeley Eye Center
Myopia
Wearability of and Myopia Progression With ZEISS MyoCare Spectacle Lenses
This is a clinical trial evaluating the wearability and effectiveness of three types of ZEISS spectacle lenses in controlling myopia progression.
- Trial name
- NCT07021560
- Testing
- ZEISS MyoCare spectacle lenses, ZEISS SV RX SPH 1.5, ZEISS Clearview
- Where
- Vietnam
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- ZEISS Vision Care
Myopia
Clinical Trial Protocol for Safety and Efficacy of Soft Contact Lens
This project is a multi-center, randomized, parallel-controlled, non-inferior clinical trial of soft contact lenses.
- Trial name
- NCT04299243
- Testing
- Contact Lenses
- Where
- China
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Menicon Co., Ltd.
Myopia
Wavefront-guided vs. Topography-guided LASIK
The study is comparing outcomes of wavefront-guided LASIK to topography-guided LASIK in a randomized contralateral fellow eye study in myopic participants.
- Trial name
- NCT05588882
- Testing
- Wavefront-guided LASIK, Wavefront-guided
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Stanford University
Myopia
Dispensing Overnight Study in Lenses
The purpose of the study is to evaluate the fit and performance of an investigational soft contact lens in comparison with a currently marketed lens.
- Trial name
- NCT00349856
- Testing
- Biofinity
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Myopia, Visual Diet
Longitudinal Measurements of Visual Diet in Children
Myopia is a leading cause of visual impairment worldwide, with prevalence rising rapidly among children. Growing evidence suggests that environmental and behavioral factors play a dominant role in ocular growth; however, current…
- Conditions
- Myopia, Visual Diet, Pupil, Viewing Distance
- Trial name
- VEET (NCT07642999)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- State University of New York College of Optometry
Myopia
Characterization of the Corneal Biomechanics of Patients Treated by Corneal Lenticule Extraction for Advanced Refractive Correction (CLEAR) to Correct Myopia
This study aims to perform biomechanical tests on extracted CLEAR lenticles that are routinely discarded after surgery. The investigators also aim to perform Brillouin microscopy to get an in-vivo assessment of the patient's…
- Trial name
- CLEAR Biomech (NCT04817592)
- Testing
- Corneal lenticule extraction for advanced refractive correction (CLEAR)
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Bern