Clinical trials: Myopia; Refractive Error
Refractive Surgery
Comparison Between the SBK Microkeratome Versus Femtosecond Laser in Flap Creation During LASIK Surgery for Myopia
LASIK is the most commonly performed refractive surgery worldwide. It has been shown to be safe and effective procedure with predictable results over long term follow ups.
- Trial name
- NCT05406973
- Testing
- SBK microkeratome versus femtosecond laser in flap creation
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Visual Developmental Disorders
Tertiary Care for Visual Developmental Disorders in Pre-school Children
Visual development disorders are major public health problems among children especially in China. How to find an effective and economic way to manage the larger number of children in China remains exploring.
- Trial name
- NCT03251456
- Testing
- Tertiary care, Usual Care
- Where
- China
- Volunteers
- 1,114 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Myopia
Baseline Relative Peripheral Refraction in Myopia Control
Myopia has become a world concern and its prevalence has increased in recent decades. Myopic defocus has been applied for slowing down the axial elongation and myopia progression, which is mainly based on the theory of…
- Trial name
- NCT06161311
- Testing
- DIMS lenses
- Where
- Hong Kong
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Adolescent, Adult
Prospective Clinical Study of Retinal Microvascular Alteration After ICL Implantation
To observe the retinal microvascular alteration during 3 months follow-up after Implantable Collamer Lens (ICL) operation in moderate and high myopia patients using quantitative optical coherence tomography angiography (OCTA)…
- Conditions
- Adolescent, Adult, Human, Male
- Trial name
- NCT04443231
- Testing
- Optical Coherence Tomography Angiography
- Where
- China
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Myopia
Dual Focus Soft Contact Lens Wear Cessation Study
The purpose of this study is to investigate the effect of ceasing treatment with dual focus soft contact lenses.
- Trial name
- NCT05779072
- Testing
- Single Vision Soft Contact Lens
- Where
- 4 sites in Canada, Portugal and 2 more
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia, Astigmatism
Changes Between Lenticule Extraction and Femtosecond Laser-assisted Laser in Situ Keratomileusis
The aim is to evaluate the short-term changes in ocular surface measures and tear inflammatory mediators after lenticule extraction (FLEx) and femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK) procedures.
- Trial name
- NCT02550353
- Testing
- lenticule extraction, femtosecond laser-assisted laser in situ keratomileusis
- Where
- China
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Myopia, Corneal Crosslinking
Advanced Cross Linking for Low-grade Myopia
To evaluate the improvement in myopic refractive error and the corneal endothelial safety with a corneal crosslinking treatment regimen for mild myopia.
- Trial name
- PiXLO2 (NCT03197272)
- Testing
- PiXL
- Where
- Sweden
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Umeå University
Myopia, Hyperopia
Multicenter Dispensing Study of Biofinity Lenses in Extended Range
To obtain subjective and objective feedback on the clinical performance of Biofinity lenses after at least two weeks daily wear in existing contact lens wearers compared with their habitual lenses.
- Trial name
- NCT02060539
- Testing
- Biofinity XR
- Where
- 4 sites in United States, Canada
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia
LSH Silicone Hydrogel Soft Hydrophilic Contact Lens for Daily Wear
This study is to evaluate the performance of the LSH (mangofilcon A) silicone hydrogel soft contact lenses when used as a daily wear contact lens for the correction of myopia.
- Trial name
- NCT01735045
- Testing
- Lagado LSH (mangofilcon A) Soft (hydrophilic) Contact Lens, Benz 3GX (hioxifilcon B) Soft (hydrophilic) Contact Lens
- Where
- 5 sites in United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Szabocsik and Associates, Inc.
Myopia
Evaluating NeuroVision's Neural Vision Correction (NVC) Myopia Treatment
The purpose of the present study is to carry out a trial to evaluate the clinical efficacy of the NeuroVision Low Myopia Treatment. The specific questions to be answered are: 1.
- Trial name
- NCT00469612
- Testing
- NeuroVision's NVC treatment for Low Myopia
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Presbyopia, Refractive Errors
Evaluation of the Safety and Effectiveness of Aceclidine/Brimonidine (LNZ101) and Aceclidine (LNZ100) in the Treatment of Presbyopia
To evaluate the safety and effectiveness of Aceclidine/Brimonidine (LNZ101) compared with Aceclidine (LNZ100) and vehicle in the treatment of Presbyopia.
- Conditions
- Presbyopia, Refractive Errors, Eye Diseases
- Trial name
- NCT05294328
- Testing
- Aceclidine+Brimonidine combination ophthalmic solution, Aceclidine ophthalmic solution, Vehicle Proprietary Ophthalmic Solution
- Where
- 5 sites in United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- LENZ Therapeutics, Inc
Myopia
Stellest Lenses and Low-concentration Atropine Myopia Control Among Children
The prevalence of myopia is increasing globally, especially in Asian countries. 70-80% of the young population suffers from myopia, and almost 20% have high myopia.
- Trial name
- NCT06344429
- Testing
- Stellest Lenses, Stellest Lenses+0.05% atropine, Single vision Lenses+0.05% atropine
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Essilor-Polylite Taiwan Co., Ltd.
Myopia, Light; Therapy, Complications
Optimizing Light Exposure for Myopia Prevention and Control (LightSPAN)
The goal of this clinical trial is to evaluate whether the optimization of daily exposure to light in primary school children can lead to better myopia prevention and control.
- Conditions
- Myopia, Light; Therapy, Complications, Myopia Progression, Short-Sighted
- Trial name
- LightSPAN (NCT06631339)
- Testing
- Light Intervention, Digital Intervention, Control Group
- Where
- 5 sites in Singapore
- Volunteers
- 396 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Myopia
The Effect of Blue-light Filtering Spectacle Lenses on Myopia Progression in Schoolchildren
The purpose of this study is to investigate if the blue-light filtering spectacle lenses promote myopia progression in schoolchildren.
- Trial name
- NCT03538002
- Testing
- Blue-light filtering spectacle lenses
- Where
- Hong Kong
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Myopia, Refractive Errors
Real-World Study of Myopia Prevention and Control in Children
This prospective, school-based cohort study aims to enroll approximately 15,000 primary school students from multiple districts in Shanghai, China and to observe the outcomes on myopia prevention and control in children with…
- Conditions
- Myopia, Refractive Errors, Children, Cohort
- Trial name
- NCT06849895
- Where
- China
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Myopia
A Prospective, Contralateral, Eye to Eye Comparison of SMILE Surgery to LASIK Surgery
Subjects will undergo SMILE surgery in one eye and LASIK surgery in their other eye to correct myopia.
- Trial name
- NCT03067077
- Testing
- SMILE, LASIK
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Stanford University
Myopia, Hyperopia
Corneal and Conjunctival Sensitivity and Staining Study
The primary objective of this study is to compare subjective symptoms and ocular health in a group of individuals who are currently wearing soft contact lenses on a daily wear basis, after a short period of no lens wear and…
- Trial name
- NCT00455455
- Testing
- Optifree RepleniSH Multipurpose Disinfecting Solution, ReNu Multiplus Multipurpose Solution
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Blindness,Visual Impairment, Refractive Error, Cataract, High Myopia, Aging
Shanghai Eye Study for Adults
Blindness and visual impairment severely impact the visual health and life quality of people, particularly the 2.566 million senior citizens aged at 65 and above in Shanghai.
- Trial name
- SESA (NCT03455478)
- Testing
- spectacles
- Where
- China
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Myopia,, Hyperopia,
Refraction Determination Analysis
Correlating the accuracy of a refraction done over telemedicine to that of a standard refraction, with a study hypothesis that the results will be equivalent.
- Conditions
- Myopia,, Hyperopia,, Astigmatism,, Presbyopia,
- Trial name
- NCT01995435
- Testing
- Telemedicine refraction, Traditional refraction
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Lee, Steven, M.D.
Myopia
To Evaluate the Efficacy and Safety of Multifocal Soft Contact Lens in Myopia Control
The objective of this study is to investigate the efficacy and safety of soft lens in myopia control.
- Trial name
- NCT03413085
- Testing
- soft contact lens
- Where
- 3 sites in Taiwan
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Largan Medical Co., Ltd.