Clinical trials: Myopia; Refractive Error
Myopia, Myopia, Progressive
Kubota Glass Parameter Refinement Study
Length of the eye will be measured in subjects exposed to various stimulus characteristics using an electronic spectacle which presents illuminated targets to the eye.
- Conditions
- Myopia, Myopia, Progressive, Vision Disorders
- Trial name
- NCT06085430
- Testing
- Kubota Glass
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Kubota Vision Inc.
Myopia, Astigmatism
Z8 OCT-controlled 2D vs 3D LASIK
The aim of this study was to test the hypothesis that OCT-guided 110 µm targeted flaps will result in accurate, predictable, and precise thickness flaps, with low complication rates when performed and compared using both 2D and…
- Trial name
- NCT04426175
- Testing
- 2D and 3D cutting method using a low energy Femtosecond laser LDV Z8 for LASIK flap cutting
- Where
- Germany
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Zentrumsehstarke Hamburg
Myopia
Performance Evaluation of Different Daily Disposable Silicone Hydrogel Contact Lenses
The goal of this study is to compare the performance of two daily disposable silicone hydrogel contact lenses.
- Trial name
- NCT05805059
- Testing
- Control Contact Lens (stenfilcon A), Test Contact Lens (senofilcon A)
- Where
- 4 sites in United States, Canada
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia, Hyperopia
Comparative Evaluation of Corneal Staining With Balafilcon A Lenses and Two Multi-Purpose Solutions
A new multi-purpose solution (MPS)was clinically evaluated against Opti-Free RepleniSH MPS at specific time points over the course of four days. The study was conducted with PureVision lenses.
- Conditions
- Myopia, Hyperopia, Astigmatism
- Trial name
- NCT01024855
- Testing
- RevitaLens OcuTec MPS (Investigational MPS) and Opti-Free RepleniSH MPS (control)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Myopia, Myopia, Progressive
Study to Evaluate the Efficacy of Alleance® (Atropine Sulfate 0.01%) as a Treatment to Delay Myopia and Axial Ocular Elongation in Children.
Phase III clinical study to evaluate the efficacy of Alleance® (atropine sulfate 0.01%) ophthalmic solution through the incidence of unexpected adverse events, changes in Best Corrected Visual Acuity (BCVA), changes in…
- Trial name
- NCT06389110
- Testing
- Alleance®
- Where
- Mexico
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Laboratorios Sophia S.A de C.V.
Myopia
Study of the MEL 80 Excimer Laser Using LASIK in the Treatment of Moderate to High Myopia
The purpose of this study is to determine whether the MEL 80 Excimer Laser is effective in the treatment of moderate to high myopia (nearsightedness), when used as part of the Laser In Situ Keratomileusis (LASIK) procedure.
- Trial name
- NCT00762541
- Testing
- MEL 80 Treatment of High Myopia
- Where
- 5 sites in United States
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Carl Zeiss Meditec, Inc.
Nearsightedness, Astigmatism
High Resolution Wavefront-guided vs. Wavefront Optimized LASIK
The investigators are comparing outcomes of LASIK surgery using a high definition wavefront-guided laser to a wavefront-optimized laser in patients with nearsightedness with and without astigmatism.
- Trial name
- NCT02565537
- Testing
- LASIK
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Stanford University
Presbyopia
Safety & Efficacy of Pilocarpine Eye Solutions for Temporary Improvement of Near Vision in Presbyopic Adults
Volunteer participants are evaluated for eligibility during a Screening Visit; those meeting study inclusion/exclusion criteria are scheduled for 3 treatment visits.
- Trial name
- VISION-1 (NCT04657172)
- Testing
- Pilocarpine Ophthalmic
- Where
- 9 sites in United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Eyenovia Inc.
Myopia
Corneal Biomechanics Study
The goal of the study is to investigate relationship between the corneal response to a temporary increase in intraocular pressure and corneal mechanical properties.
- Trial name
- NCT03658239
- Testing
- Inversion
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Rochester
Primary Open Angle Glaucoma, Myopia
Diagnostic Innovations in Glaucoma Study
The overarching goal of our research study is to evaluate changes in visual function and optic nerve topography (the structure of the back of the eye) in patients with glaucoma (increased susceptibility to pressure inside the eye…
- Trial name
- DIGS (NCT00221897)
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Myopia
Multi-Centre Clinical Evaluation of Two Reusable Soft Contact Lenses
The aim of this study is to compare the subjective performance of the comfilcon A contact lens against lotrafilcon B contact lens after 4 weeks of reusable lens wear.
- Trial name
- NCT02815735
- Testing
- comfilcon A, lotrafilcon B
- Where
- 9 sites in United Kingdom
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia, Quality of Life
Functional Vision and Quality of Life in a Modern Society - With Emphasis on Myopia and Cerebral Visual Impairment Among Youth
Society has become increasingly digital, and many everyday services have been replaced by digital self-service solutions. This puts greater demands on our vision and our ability to interpret what we see.
- Trial name
- NCT07653074
- Testing
- ophthalmological examination
- Where
- Sweden
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Region Örebro County
Myopia
Product Performance of a Daily Disposable Contact Lens
The objective of this one week, single group, bilateral, open-label study is to evaluate the product performance of the Bausch \& Lomb daily disposable cosmetic tint contact lens (Test) when worn on a daily disposable basis by…
- Trial name
- NCT01230554
- Testing
- Daily disposable cosmetic tint lens
- Where
- Singapore
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Myopia
Adaptation To and Satisfaction With Contact Lens Wear In Myopic Young Adults
The purpose of this study was to assess whether young adults could adapt to and achieve satisfaction with a daily disposable contact lens.
- Trial name
- NCT04857723
- Testing
- daily disposable contact lens
- Where
- Canada
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia, Astigmatism
Changes Between Lenticule Extraction and Femtosecond Laser-assisted Laser in Situ Keratomileusis
The aim is to evaluate the short-term changes in ocular surface measures and tear inflammatory mediators after lenticule extraction (FLEx) and femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK) procedures.
- Trial name
- NCT02550353
- Testing
- lenticule extraction, femtosecond laser-assisted laser in situ keratomileusis
- Where
- China
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Myopia, Hypermetropia
Anesthetic Impregnated Bandage Soft Contact Lens (BSCL) in Pain Management After Photorefractive Keratectomy (PRK)
Compared to laser-assisted in situ keratomileusis (LASIK), Photorefractive Keratectomy (PRK) is associated with more discomfort and requires more downtime.
- Conditions
- Myopia, Hypermetropia, Refractive Errors, Astigmatism
- Trial name
- NCT04283331
- Testing
- Proparacaine Ophthalmic
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Beeran Meghpara, MD
Refractive Errors
Study to Evaluate the Safety and Efficacy of HI-BRITE Large Diameter Rigid Gas Permeable Contact Lens
Study to evaluate the safety and efficacy of HI-BRITE large diameter rigid gas permeable contact lens (hexafocon b) test when worn on a daily wear basis in the correction of myopia/hyperopia/astigmatism/presbyopia/ and irregular…
- Trial name
- NCT02812316
- Testing
- HI-BRITE Large Diameter Rigid Gas Permeable Contact Lens
- Where
- Taiwan
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University Hospital
Myopia
The Different Design of Orthokeratology
In this study, we intend to enroll orthokeratology subjects aged 8-18 years old with binocular myopia up to and including -4.00 D.
- Trial name
- NCT05956704
- Testing
- Orthokeratology with aspheric wide inversion zone design in the optical zone, Orthokeratology with traditional spherical design in the optical zone
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Near Vision, Refractive Error Correction
Clinical Outcomes of the Use of a Femtosecond Laser Treatment in a Patient With Implanted Monofocal IOLs
This study aims to assess the safety and efficacy of evaluating near vision or refractive error in eyes implanted with a mono focal intraocular lens (IOL) using a low-energy femtosecond laser.
- Trial name
- NCT07447622
- Testing
- Device
- Where
- Czechia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Perfect Lens, LLC
Myopia
Performance Comparison Between Comfilcon A and Senofilcon C Lenses
The aim of this study is to determine the clinical performance of comfilcon A in comparison to senofilcon C.
- Trial name
- NCT02920957
- Testing
- comfilcon A, senofilcon C
- Where
- 5 sites in United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.