Clinical trials: Myopia
Myopia, Progressive, Children, Only
Eleven Years of Menicon Z Night Contact Lens Wear in Reducing Myopia Progression in Children
To compare axial length growth of white European myopic children wearing Menicon Z Night orthokeratology contact lenses to a control group of distance, single-vision glasses and contact lenses over an 11-year period.
- Trial name
- MCOS11 (NCT04806711)
- Testing
- Menicon Z Night, Control
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Menicon Co., Ltd.
Myopia
Effect of MyopiaEd Messaging on Improving Eye-use Behavior and Myopia Control Among Primary School Students in China
Myopia represents a significant global public health challenge, with China experiencing particularly high myopia prevalence among children and adolescents.
- Trial name
- NCT07211893
- Testing
- Send myopia-related health education message
- Volunteers
- 1,330 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Myopia, Astigmatism
SMILE (Small Incision Lenticule Extraction) in the DoD (Department of Defense)
The Use of the VisuMaxTM Femtosecond Laser Small-Incision Lenticule Extraction (SMILE) Procedure for the Correction of Myopia with or without Astigmatism study is a prospective, non-randomized, multicenter clinical study that…
- Trial name
- NCT04072289
- Testing
- Visumax spherocylindrical treatment
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, San Diego
Human Myopia Model
Clinical Research Plan for Human Myopia Models
Collect optical biological parameters, refractive index data, and other related parameters of myopia and refractive errors in children and adolescents, and establish an optical model of myopia in children and adolescents.
- Trial name
- NCT06185868
- Testing
- No intervention measures
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Robotrak Technologies Co., Ltd.
Myopia, Myopia, Progressive
Multicenter RCT: LED Red Light Dose-Response in Myopia Progression Control
The goal of this clinical trial is to verify the effectiveness and safety of non-laser LED red light combined with defocus lens therapy for controlling myopia progression and evaluate the impact of different intervention…
- Trial name
- NCT07330180
- Testing
- Yingtong Vision Rehabilitation Instrument, Hoya DIMS multi-point myopia defocus lens
- Where
- 7 sites in China
- Volunteers
- 364 people, healthy volunteers welcome
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Dark Focus of Accommodation
Night Myopia and Dark Focus of Accommodation
Shifts in accommodation at decreasing luminance levels are considered as principle cause for night myopia. Previous studies with laser optometers quantified the dark focus of accommodation up to 3 D.
- Trial name
- NCT03358550
- Testing
- Accommodation Measurement
- Where
- Germany
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Applied Sciences Jena
Myopia, Refractive Errors
Light Emitting Diodes With a Continuous Spectrum of 430-780nm for Myopia Prevention
The purpose of this clinical trial is to evaluate the effect of light-emitting diodes (LEDs) with a continuous spectrum of 430-780 nm for lighting in the classroom on myopia prevention among children in Grades 2 and 3.
- Conditions
- Myopia, Refractive Errors, Eye Diseases
- Trial name
- NCT05728762
- Testing
- Novel LEDs
- Where
- China
- Volunteers
- 1,920 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Myopia
Noninvasive and Dynamic Monitoring the Biological Parameters of Eyes in Different Age Groups
Myopia is the most common refractive eye disease worldwide. The number of cases is up to 2 billion. In recent years, the incidence of myopia in China is obviously rising trend.
- Trial name
- NCT05250440
- Where
- China
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Zhongnan Hospital
Myopia (Disorder), Astigmatism
Optical Quality of the Cornea in Orthokeratology
Analyzing Optical Quality After the Use of Overnight Orthokeratology (Ortho-K)
- Trial name
- COPCORTO (NCT06775509)
- Testing
- Ortho-K
- Where
- Spain
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Institut Investigacio Sanitaria Pere Virgili
Myopia, Randomized Controlled Trials
Effect of a Myopia Prediction System on Myopia Prevention and Control
The global rise in myopia, particularly among children and adolescents in China, underscores the inadequacy of current prevention strategies, indicating that conventional screening and education alone are insufficient to curb the…
- Conditions
- Myopia, Randomized Controlled Trials, Artificial Intelligence (AI)
- Trial name
- NCT06633393
- Testing
- Feedback on Predicted High Myopia Risk at Age 18 Using the Myopia Prediction System, Feedback on Ophthalmic Examinations
- Where
- China
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Myopia, Myopic Astigmatism
Using the VisuMax Femtosecond Laser System to Perform SMILE Optimized for Presbyopia by Modulation of Postoperative Spherical Aberration
The intended purpose of the investigational device in the study is the correction of myopia and myopia with astigmatism in the CE (Conformité Européene) approved range and optimized for presbyopic patients using the treatment…
- Conditions
- Myopia, Myopic Astigmatism, Presbyopia
- Trial name
- NCT05684237
- Testing
- HiSMILE treatment option
- Where
- United Kingdom
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- London Vision Clinic
Myopia
Myopia Prevention With Reading Glasses
The last decades have seen a significant increase in myopia in children and young adults. Possible cause: increased near-work (school, computer, smartphone).
- Trial name
- SMART2 (NCT05030103)
- Testing
- Reading glasses, +2.0 diopters
- Where
- Liechtenstein
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Reis Augenklinik AG
Myopia
Clinical Performance of Existing Wearers of Enfilcon A Following a Refit With Fanfilcon A Lenses for 4 Weeks
The aim of this dispensing study is to evaluate the clinical performance of habitual wearers of enfilcon A lenses following a refit with fanfilcon A lenses over 4 weeks of daily wear.
- Trial name
- NCT02670473
- Testing
- fanfilcon A (test)
- Where
- Spain
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia
The Effect of Blue-light Filtering Spectacle Lenses on Myopia Progression in Schoolchildren
The purpose of this study is to investigate if the blue-light filtering spectacle lenses promote myopia progression in schoolchildren.
- Trial name
- NCT03538002
- Testing
- Blue-light filtering spectacle lenses
- Where
- Hong Kong
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Multiple Sclerosis, Dry Eye Syndromes
Clinical Applications of Advanced Ophthalmic Imaging
The purpose of this study is to determine the clinical application of advanced ophthalmic imaging devices such as optical coherence tomography (OCT), retinal function imager (RFI), slit-lamp biomicroscopy (SLB), PERG in diseased…
- Conditions
- Multiple Sclerosis, Dry Eye Syndromes, Diabetic Retinopathy, Presbyopia
- Trial name
- NCT03135327
- Testing
- Ocufolin
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- University of Miami
Myopia
Impact of Ultraviolet Radiation and Environmental Factors on Human Ocular Biomechanics
This observational study aims to explore whether ultraviolet (UV) radiation and other environmental factors are associated with ocular biomechanical properties in healthy volunteers aged 18-44 years without ocular diseases…
- Trial name
- NCT06993077
- Testing
- environment Exposure
- Where
- China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Visual Acuity
Visual Performance of Soft Contact Lenses With Myopia Control Optics
This is a multi-site, bilateral, dispensing, randomized, controlled, single-masked, 3x3 crossover study with a run-in period.
- Trial name
- NCT05141448
- Testing
- 1-Day Acuvue Moist, EMO-118, EMO-114
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia
A Two-Week Crossover Dispensing Evaluation Of Orion Daily Wear Soft Contact Lens
The primary objective of the study is to evaluate the clinical performance of test lens (Orion) in comparison with control lens (Gemini) over a period of two weeks of wear.
- Trial name
- NCT04585646
- Testing
- Orion daily disposable contact lens, Gemini daily disposable contact lens
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia
Changes in Eye Shape With Myopia Management Interventions
The goal of this clinical trial is to study changes in eye shape of nearsighted young adults using low-dose atropine eye drops or soft multifocal contact lenses.
- Trial name
- NCT06450132
- Testing
- Atropine Ophthalmic, MiSight 1-day disposable contact lenses
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Refractive Errors, Myopic Astigmatism
Evaluation of Different Lenticule Diameters in Myopic Astigmatism Correction With SMILE Procedures
Small incision lenticule extraction (SMILE) is a refractive intrastromal procedure for myopia and myopic astigmatism correction.
- Trial name
- NCT06062004
- Testing
- Small Incision Lenticule Extraction (SMILE)
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Al Watany Eye Hospital