Clinical trials: Myopia
Visual Developmental Disorders
Tertiary Care for Visual Developmental Disorders in Pre-school Children
Visual development disorders are major public health problems among children especially in China. How to find an effective and economic way to manage the larger number of children in China remains exploring.
- Trial name
- NCT03251456
- Testing
- Tertiary care, Usual Care
- Where
- China
- Volunteers
- 1,114 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Myopia, Progressive
To Evaluate the Efficacy and Safety of an Defocus Lens in Slowing the Progression of Myopia
To confirm the efficacy of DIMS lenses in controlling myopia progression, we planned a prospective, single-centre, randomised, double-blind, controlled, non-inferiority clinical study.
- Trial name
- NCT06405711
- Testing
- frame lens
- Where
- China
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Myopia, Hyperopia
APIOC Sphere and APIOC Astigmatism
Vision and comfort, both objective and subjective, will be assessed for single vision contact lens wearers for either the APIOC™ Sphere or the APIOC™ Astigmatism contact lenses.
- Conditions
- Myopia, Hyperopia, Astigmatism
- Trial name
- NCT04806802
- Testing
- APIOC Sphere and APIOC Astigmatism
- Where
- 6 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Lentechs, LLC
Myopia, Visual Fatigue
Discussion on the Effectiveness of Tea on Blood Pressure, Body Composition and Vision Problems in College Students
Background: Tea is a universal beverage and one of the most popular drinks around the world. Some cell and animal experiments have pointed out that drinking tea may be related to hypotension, body composition and vision problems…
- Conditions
- Myopia, Visual Fatigue, Blood Pressure, Body Composition
- Trial name
- NCT06570226
- Testing
- hibiscus tea
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hungkuang University
Myopia, Ametropia
LED Low-Intensity Red Light for Myopia Control in Youth: Efficacy and Safety Study
The purpose of this clinical trial was to investigate the efficacy and safety of repetitive low-intensity single-wavelength red light from an LED light source in controlling myopia progression in children and adolescents.
- Trial name
- NCT07375589
- Testing
- Red light treatment with 1.6mW LED light source, Red light treatment with 0.001mW LED light source
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Keratomileusis, Laser In Situ
The Role of Psychosocial and Other Quality of Life Parameters in Evaluating Functional Changes Prior to and Following Laser In-situ Keratomileusis (LASIK)Changes Laser In-situ Keratomileusis (LASIK)
To evaluate the changes in quality of life parameters after LASIK surgery.
- Trial name
- NCT00344604
- Testing
- Role of psychosocial and quality of life parameters prior to and following LASIK.
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Myopia, Hyperopia
Evaluation of Silicone Hydrogel Daily Wear Contact Lenses for Up to One (1) Month of Daily Wear
The aim of the study is to evaluate if the performance of Invigor A is substantially equivalent to Invigor B contact lenses when used in a one month recommended replacement, daily wear modality.
- Conditions
- Myopia, Hyperopia, Astigmatism
- Trial name
- NCT03722784
- Testing
- Invigor A (test), Invigor B (control)
- Where
- 6 sites in United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia
Impact of Positive & Negative Lens-Induced Defocus on Contrast-Sensitivity in Myopic & Non-Myopic Adults
examines the influence of lens-induced defocus on contrast sensitivity-a crucial aspect of visual performance.Each participant experiences both positive and negative defocus through different lenses, with measurements taken for…
- Trial name
- NCT06753032
- Testing
- Positive Lens-Induced Defocus Using Spectacle Lenses (+2.00 D) for Myopic Participants, Negative Lens-Induced Defocus Using Spectacle Lenses (-2.00 D) for Myopic Participants, Positive Lens-Induced Defocus Using Spectacle Lenses (+2.00 D) for Non-Myopic Participants
- Where
- Pakistan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Superior University
High Myopia
Development and Pathological Changes of High Myopia Among Children and Adolescents in China
The study aims to observe the relationship between the changes of ocular structure parameters and pathological changes among children and adolescents with high myopia.
- Trial name
- NCT03533647
- Testing
- Observational
- Where
- China
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Glaucoma
Normative Database of the Retinal Nerve Fiber Layer Thickness Measured by the Cirrus HD OCT in Asians
The normal range of retinal nerve fiber layer thickness might be different between Asians and Caucasians. However, the recently developed imaging device such as the Cirrus HD OCT includes only the Caucasian data.
- Trial name
- NCT00744705
- Where
- South Korea
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Induced Defocus to the Retina
Defocus Induced Changes on Choroidal Thickness
The goals of this study are to assess the short-term (10-60 minutes) effects of different magnitudes of myopic and hyperopic optical defocus on the transient thickness of the choroid in children and adults, as well as to assess…
- Trial name
- NCT03954886
- Testing
- Plus powered optical lens
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Houston
Myopia, Astigmatism
Contralateral Study of Topography Guided LASIK Versus Small Incision Lenticule Extraction
This study evaluates differences in postoperative visual outcomes between patients receiving Topography-Guided LASIK in one eye and Small Incision Lenticule Extraction in the other eye.
- Trial name
- NCT05611294
- Testing
- Topography Guided LASIK Surgery, Small Incision Lenticule Extraction Surgery
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Hoopes Vision
Myopia
Association of Genetic Variants With Myopia
This study aims to identify genetic factors linked to myopia, including those that influence a person's risk of developing it and how quickly it progresses (like changes in eye length).
- Trial name
- NCT07030153
- Testing
- Oral swab DNA analyzed for myopia-related gene variants
- Where
- 2 sites in China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Beijing Visionly Plus Eye Hospital
Myopia
Phase 1 Study of SHJ002 Sterile Ophthalmic Solution in Pediatric Subjects
This is a single-center, open-label, first-in-human dose-escalation study of SHJ002 Ophthalmic Solution in children. (Part 1) Three (3) subjects will receive each concentration of SHJ002 for 3 days in an escalation design in one…
- Trial name
- NCT04928144
- Testing
- SHJ - Low concentration, SHJ - Mid concentration, SHJ - High concentration
- Where
- Taiwan
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Sunhawk Vision Biotech, Inc.
Myopia, Safety Issues
The Safety and Effectiveness of Breath-O Lenses
In Hong Kong, approximately 80% of children are myopic by the end of childhood. There is intense interest currently in the potential role of peripheral defocus as a clinical treatment to slow myopia progression.
- Trial name
- NCT03616600
- Testing
- Breath-O-Correct Lens
- Where
- Hong Kong
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Myopia
Axial Length With Adult Onset Myopia (ALWAOM)
Purpose: To determine axial length progression and its relationship with myopia onset and progression in adults.
- Trial name
- ALWAOM (NCT05559567)
- Testing
- Orthokeratology
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Art Optical Contact Lens, Inc.
Myopia
Controlling Myopia Progression With Soft Contact Lenses (Contact Lens Control)
This study is to investigate whether novel soft contact lens optical designs can slow myopia progression
- Trial name
- NCT01829191
- Testing
- Soft Contact Test Lens A, Soft Contact Test Lens C
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia, Hyperopia
One-month Clinical Evaluation of Oté Sensation Multi-Purpose Solution Care System
The purpose of this study is to evaluate the clinical performance of the contact lens care product Oté Sensation in a representative population of soft contact lens wearers.
- Trial name
- NCT03278223
- Testing
- Test solution, Control solution
- Where
- 11 sites in United States, United Kingdom
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- OTE North America
Myopia
Evaluation of the Performance of Different Daily Disposable Lens Designs in Habitual Soft Contact Lens Wearers
The main objective of the study is to refit existing soft lens wearers with two different daily disposable contact lens types, Lens A and Lens B, to determine their performance after one week of wear.
- Trial name
- NCT04668989
- Testing
- stenfilcon A - (Test lens), kalifilcon A - (Control Lens)
- Where
- 4 sites in United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Presbyopia
Using AGN-190584 in Subjects Utilizing Single -Use Daily, Contact Lenses
AGN-190584 has gone through many clinical trials showing its safety and effectiveness in individuals from 40-55 years of age. There has been no published data on the use of this product in individuals corrected with contact…
- Trial name
- NCT05624320
- Testing
- AGN-190584
- Volunteers
- healthy volunteers welcome
- Sponsor
- Gordon Schanzlin New Vision