Clinical trials: Myopia
Myopia, Astigmatism
A Prospective Study of Femtosecond Laser Intracorneal Lensectomi
The purpose of this study is to compare visual acuity, safety, predictability, corneal biomechanics, dry eyes, and nerve-morphology after all femtosecond laser refractive lenticule extraction.
- Trial name
- NCT01673503
- Testing
- Carl Zeiss Meditech VisuMax laser
- Where
- Denmark
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Emmetropia, Myopia
Effects of Light on the Choroid and Pupil
Monochromatic light creates longitudinal chromatic aberration, with short wavelength blue light forming a focal point in front of the retina and long wavelength red light forming a focal point behind the retina.
- Trial name
- NCT05852782
- Testing
- White Light therapy, Blue light therapy, Red light therapy
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Houston
Multiple Sclerosis, Dry Eye Syndromes
Clinical Applications of Advanced Ophthalmic Imaging
The purpose of this study is to determine the clinical application of advanced ophthalmic imaging devices such as optical coherence tomography (OCT), retinal function imager (RFI), slit-lamp biomicroscopy (SLB), PERG in diseased…
- Conditions
- Multiple Sclerosis, Dry Eye Syndromes, Diabetic Retinopathy, Presbyopia
- Trial name
- NCT03135327
- Testing
- Ocufolin
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- University of Miami
Myopia
The Effects of Low Dose Atropine on Choroidal Thickness
Atropine eye drops are considered to be an effective form of myopia control in human eyes. However, the mechanism by which it exerts it effects are not fully understood.
- Trial name
- NCT03544827
- Testing
- Atropine
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- State University of New York College of Optometry
Myopia
To Evaluate the Efficacy and Safety of Multifocal Soft Contact Lens in Myopia Control
The objective of this study is to investigate the efficacy and safety of soft lens in myopia control.
- Trial name
- NCT03413085
- Testing
- soft contact lens
- Where
- 3 sites in Taiwan
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Largan Medical Co., Ltd.
Myopia
Combination Effect of Optical Defocus and Low Dose Atropine in Myopia Control
The purpose of the study is to investigate the combination effect of optical defocus and low dose atropine on myopia control in schoolchildren.
- Trial name
- NCT06358755
- Testing
- Defocus Incorporated Multiple Segments lenses, single vision spectacle lenses, Low dose atropine
- Where
- Hong Kong
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Myopia
Wavefront-guided vs. Topography-guided LASIK
The study is comparing outcomes of wavefront-guided LASIK to topography-guided LASIK in a randomized contralateral fellow eye study in myopic participants.
- Trial name
- NCT05588882
- Testing
- Wavefront-guided LASIK, Wavefront-guided
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Stanford University
Myopia
Safety and Tolerability Evaluation of PRO-230 Ophthalmic Solution
Phase I Study to evaluate safety and tolerability of PRO-230 (atropine sulphate 0.05%) ophthalmic solution through evaluation of incidence of non-expected adverse events (AE), photophobia, pupillary diameter, incidence of…
- Trial name
- PRO-230 (NCT05481489)
- Testing
- Atropine Sulfate
- Volunteers
- healthy volunteers welcome
- Sponsor
- Laboratorios Sophia S.A de C.V.
Choroidal Retinal Neovascularization
Aflibercept Intravitreal Injection for Myopic Choroidal Neovascularization
The purpose of this study is to evaluate the clinical results of anti-VEGF intra-vitreal injections (IVT) in CNV secondary
- Trial name
- AflibxMyopia (NCT02033018)
- Testing
- Aflibercept Injection
- Where
- 2 sites in Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Instituto de Olhos de Goiania
Myopia, Progressive
A Unified Index to Predict the Success Probability of Myopia Control
Orthokeratology lenses (OK-lens) and multifocal contact lenses (MFCL) are optical devices designed to slow down the progression of myopia. Both treatments a long-term commitment from doctors and patients.
- Trial name
- NCT05773118
- Testing
- orthokeratology lens, multifocal soft contact lens, Single vision spectacles
- Volunteers
- healthy volunteers welcome
- Sponsor
- Nova Southeastern University
Myopia
Aberration-Free Refraction Correction
In the interest of improving visual quality after LASIK we have designed a multifaceted study to test the theoretical, physical, biomechanical and functional effects of commercial and independently designed aspherical ablation…
- Trial name
- NCT00172913
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Myopia
A 3-year Cross-sectional Assessment of the Tianjin Child and Adolescent Large-scale Eye Study
This is a school-based, cross-sectional study to assess the incidence and prevalence, risk factors of myopia among schoolchildren in both eye-use environment, eye-use habits, lifestyle, and family and subjective factors before…
- Trial name
- NCT05967702
- Where
- China
- Volunteers
- 126,810 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Hyperopia, Myopia
On-Eye Optical Quality of Lotrafilcon B Lenses Over 12 Hours
The current study aims to systematically investigate the diurnal variation in the optical quality of soft contact lenses on eye throughout the day. Subject reported quality of vision will also be evaluated.
- Trial name
- NCT03881670
- Testing
- Lotrafilcon B, lotrafilcon B with Hydraluxe
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Indiana University
Presbyopia
Investigation of the Presbia Flexivue Microlens™
The Presbia Flexivue Microlens is a corneal inlay.
- Trial name
- NCT02110472
- Testing
- Corneal inlay
- Where
- 11 sites in United States
- Volunteers
- 412 people, healthy volunteers welcome
- Sponsor
- PresbiBio, LLC
Visual Impairment, Myopia
At-home Testing Refraction Results With Best Corrected Visual Acuity (BCVA) Outcomes in Adults
This study is aimed at examining the BCVA from try-on glasses constructed from measurements from the EyeQue VisionCheck.
- Conditions
- Visual Impairment, Myopia, Hyperopia, Astigmatism
- Trial name
- NCT04820218
- Testing
- With Try-on glasses
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- EyeQue Corp.
Myopia
Evaluation of a New Silicone Hydrogel Contact Lens
The objective of this study is to determine the clinical feasibility and to evaluate the product performance of investigational contact lenses developed by Bausch + Lomb.
- Trial name
- NCT01309880
- Testing
- Test lens, Air Optix Aqua
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Myopia
Delaying the Onset of Nearsightedness Until Treatment (DONUT) Clinical Trial
The aims of this clinical trial will test whether or not the onset of nearsightedness is delayed in a group of children randomized to nightly drops in 0.05% atropine in both eyes, in comparison to children who receiving nightly…
- Trial name
- DONUT (NCT07567040)
- Testing
- Atropine Sulfate 0.05% Oph Soln
- Where
- 13 sites in United States
- Volunteers
- 664 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Myopia
The Impact of Bright Classroom on Myopia
This trial aims to test the effectiveness and practicality of study in the Bright Classrooms with skylight and artificial light renovation in reducing incident myopia in Chinese primary school children over three years, as…
- Trial name
- IMPACT (NCT05156190)
- Testing
- bright classrooms with light level over 1000 lux
- Volunteers
- healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Age - Related Macular Degeneration (AMD), Diabetic Macular Edema
Wide Field OCTA in Ocular Diseases
The main retinal diseases, whether or not associated with specific mutations genetic, cause progressive degeneration of vascular retinal structures and not vascular, resulting in decreased visual function.
- Conditions
- Age - Related Macular Degeneration (AMD), Diabetic Macular Edema, Diabetic Retinopathy, Myopia
- Trial name
- WOOD-2025 (NCT07298174)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Myopia
Wearability of and Myopia Progression With ZEISS MyoCare Spectacle Lenses
This is a clinical trial evaluating the wearability and effectiveness of three types of ZEISS spectacle lenses in controlling myopia progression.
- Trial name
- NCT07021560
- Testing
- ZEISS MyoCare spectacle lenses, ZEISS SV RX SPH 1.5, ZEISS Clearview
- Where
- Vietnam
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- ZEISS Vision Care