Clinical trials: Myopia, active
Myopia
Myopia Control Efficacy of Second-generation DIMS Spectacle Lenses on Fast Progressing Myopes
The purpose of this study is to examine the efficacy and performance of the variant of Defocus Incorporated Spectacle lenses on controlling myopia progression in fast progressing myopic children.
- Trial name
- NCT05888792
- Testing
- Variant of Defocus Incorporated Spectacle lens (DG2)
- Where
- Hong Kong
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Myopia
The Beijing Childhood Eye Study
Axial myopia has emerged as the leading cause of irreversible vision loss in East Asia, driven by its progression to sight-threatening complications including myopic macular degeneration, retinal detachment, open-angle glaucoma…
- Trial name
- BCES (NCT06931444)
- Where
- China
- Volunteers
- 3,760 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Myopia, Myopia Progression
Contact Lenses to Slow Myopia Progression in Adults
Myopia (nearsightedness) can continue to worsen during young adulthood, increasing the risk of sight-threatening eye diseases later in life.
- Trial name
- NCT07747311
- Testing
- Dual Focus Soft Contact Lens, Single Vision Soft Contact Lens
- Where
- United States
- Volunteers
- 152 people
- Sponsor
- University of California, Berkeley
Myopia, Astigmatism
Wavefront-guided LASIK Surgery Compared to Ray Tracing-Guided LASIK Surgery
We are enrolling participants aged 22 and older to have LASIK surgery in both eyes. We will perform wavefront-guided LASIK in one eye and ray tracing-guided LASIK in the fellow eye of each participant.
- Trial name
- NCT07078799
- Testing
- LASIK
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Stanford University
Myopia Progressing
3D Designed Defocus Lenses on Myopia Control in Children and Adolescents
This study aims to evaluate the effectiveness of lenses with 3D Designed Defocus in controlling the progression of myopia in children and adolescents, and to explore the feasibility of effective design, and apply personalized…
- Trial name
- NCT07284147
- Testing
- Defocus Lenses
- Where
- China
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Myopia
Delaying the Onset of Nearsightedness Until Treatment (DONUT) Clinical Trial
The aims of this clinical trial will test whether or not the onset of nearsightedness is delayed in a group of children randomized to nightly drops in 0.05% atropine in both eyes, in comparison to children who receiving nightly…
- Trial name
- DONUT (NCT07567040)
- Testing
- Atropine Sulfate 0.05% Oph Soln
- Where
- 13 sites in United States
- Volunteers
- 664 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Children, Health Education
"Eye" Education for Parents and Myopia Control in Children
This is a randomized controlled trial aimed to explore the effect of behavioral interventions based on doctors' and nurses' health education on the onset and development of myopia in children's.
- Conditions
- Children, Health Education, Anxiety
- Trial name
- NCT06652594
- Testing
- Eye Education Intervention, Control
- Where
- China
- Volunteers
- 498 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Myopia, Astigmatism
Clinical Evaluation of WaveLight Plus LASIK
This study is a single-site, single-arm, prospective, observational study of subject satisfaction, quality of vision, and quality of life after bilateral LASIK surgery. Subjects will be assessed up to 3 months post-operatively.
- Trial name
- NCT07127757
- Testing
- Wavelight Plus LASIK
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Laser Defined Vision
Myopia, Progressive
Management of Myopia in University Students Using Dual Focus Soft Contact Lenses
The purpose of the study is to quantify the effectiveness of Coopervision MiSight contact lenses in slowing the rate of myopia progression in university students.
- Trial name
- MoMUS (NCT05955638)
- Testing
- MiSight contact lenses, Proclear contact lenses
- Where
- 2 sites in United Kingdom
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Bradford
Myopia, Myopic Astigmatism
A Clinical Trial Assessing the Safety and Effectiveness of Orthokeratology Lenses in Patients With Myopia and Myopic Astigmatism
This is a prospective, multi-centre, single-arm clinical trial to evaluate the effectiveness and safety of MCOK-01 lenses in patients with myopia and myopic astigmatism who need dioptric correction.
- Trial name
- SEMOA (NCT07047924)
- Testing
- MCOK-01
- Where
- 4 sites in Australia
- Volunteers
- 220 people
- Sponsor
- Menicon Co., Ltd.
Refractive Errors, Cycloplegic Refraction
ML Models Predicting Cycloplegic Refractive Error Based on Non-Cycloplegic Parameters in Myopic Adults
This study presents a machine learning model that predicts cycloplegic refraction in adults with myopia using standard non-cycloplegic eye measurements, aiming to reduce the need for cycloplegic drops while still identifying…
- Conditions
- Refractive Errors, Cycloplegic Refraction, Accommodation
- Trial name
- NCT07690813
- Testing
- Machine learning model for predicting cycloplegic refraction
- Where
- China
- Volunteers
- 2,500 people
- Sponsor
- Second Affiliated Hospital of Nanchang University
Myopia, Child Myopia Progression
Photolithography Microstructure Myopia Management Lenses in Preventing and Controlling Myopia in Children and Adolescents
Evaluate the effectiveness of different lithographic microstructured myopia management lenses in controlling the progression of myopia in children and adolescents, as well as the safety and comfort of wearing them.
- Trial name
- NCT07514039
- Testing
- Myopia management lens
- Where
- China
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Scoliosis Idiopathic, Myopia
Zhejiang Adolescent Spine and Vision Health Cohort: A Longitudinal Database Analysis
The aim of study: 1. To investigate the prevalence of scoliosis, other spinal deformities, myopia, and visual impairments in adolescents (aged 6-18) in Zhejiang Province.
- Conditions
- Scoliosis Idiopathic, Myopia, Vision Disorders
- Trial name
- NCT06992622
- Where
- China
- Volunteers
- 73,000 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Myopia, Healthy
Proteomic Analysis on Myopic Children Using Orthokeratology Lenses With Good or Poor Myopic Control
The key objective of the study is to gain an understanding of the biochemical processes that contribute to orthokeratology lenses being more effective in specific individuals compared to others.
- Conditions
- Myopia, Healthy, Orthokeratology
- Trial name
- ProMOC (NCT06647472)
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Vejle Hospital
Myopia
Pilot Study on the Adaptation and Tolerance of Essilor® Myopia-control Spectacle Lenses
This observational pilot study aims to evaluate the adaptation and tolerance of Essilor® Stellest® myopia-control spectacle lenses in children with progressive myopia.
- Trial name
- STELLAR (NCT07340931)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Nantes University Hospital
Myopia
Auricular Acupressure Reduces Rebound Effects After Discontinuation of Atropine
0.01% atropine is an effective measure for controlling myopia in children and is widely used in Asia for this purpose. However, there is a phenomenon of rebound and worsening of myopia after discontinuation of the medication.
- Trial name
- NCT07129889
- Testing
- gradual withdrawal of medication, Auricular acupressure
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Ningbo Eye Hospital
Myopia, Visual Rehabilitation
Exploring Perceptual Learning in Blurred Gabor Discrimination for Low-Myopic Children
This exploratory study investigates whether perceptual learning using blurred Gabor stimuli can improve uncorrected distance visual acuity in children aged 6-10 years with low myopia.
- Conditions
- Myopia, Visual Rehabilitation, Perceptual Learning
- Trial name
- NCT07107646
- Testing
- vision training system, VTS
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Taiwan University Hospital
Myopia
Effects of Blue of Glasses VS Standard Lenses on Contrast Sensitivity & Visual Fatigue in Myopic & Non-Myopic Adults
This study investigates the effects of blue light-blocking glasses compared to standard lenses on contrast sensitivity and visual fatigue in myopic and non-myopic adults.
- Trial name
- NCT06739525
- Testing
- Blue Light-Blocking Glasses (Intervention Group), Standard Lenses (Control Group)
- Where
- Pakistan
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Superior University
Cataract
Comparing Monofocal IOLs in Highly Myopic Cataract Patients
Comparison of Postoperative Outcomes in Patients with High Myopia Undergoing Cataract Surgery Implanted with Extended Depth of Focus Intraocular Lens (ICB00) and Monofocal Intraocular Lens (ZCB00)
- Trial name
- NCT06905938
- Testing
- no intervention
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Wenzhou Medical University
Astigmatism, Myopia
Evaluation of Mesopic Visual Acuity and Patient Satisfaction Following Ray-Tracing-Guided LASIK
To provide comprehensive evaluation of WaveLight® Plus technology by assessing impact on both functional low-light vision and patient reported outcomes
- Trial name
- NCT07790185
- Testing
- Wavelight Plus
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Vance Thompson Vision