Clinical trials: N/A - Healthy Subjects
Neuropathic Pain
Exploring the Role of the GABAergic Modulation in Pain Transmission in Human
Neuropathic pain affects about 7% of the general population in European countries. Meta-analyses indicate that only a minority of neuropathic pain patients has adequate response to drug therapy and management of neuropathic pain…
- Trial name
- NDMC-101 (NCT03375034)
- Testing
- NDMC 20mg, NDMC60mg, Clonazepam 1.5mg
- Where
- Switzerland
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Jules Desmeules
Diabetes
Comparative Glucose Clamp Study of Wockhardt's Human Isophane Insulin With Novolin N,in Healthy Subjects
The aim of this trial is to demonstrate bioequivalence of Wosulin N to Novolin® N with regard to its total and to its maximum serum insulin concentrations.
- Trial name
- NCT00772265
- Testing
- Wosulin N, Novolin N
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Wockhardt
Meningitis, Meningococcal
A Study Assessing Colonisation & Immunogenicity After Nasal Inoculation With N. Lactamica and Eradication on Day 4 or 14
This study is part of a project that aims to develop a vaccine with N. lactamica that prevents meningitis. The investigators have previously given nose drops containing N.
- Trial name
- Lac-3 (NCT03549325)
- Testing
- Neisseria lactamica
- Where
- United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Not Applicable - Healthy Participants, Focus is the Memory System
MEMRI: Memory Emergence Using MRI
Episodic memory is our ability to remember personal experiences, such as a birthday party or a visit to the park. This study aims to understand how this type of memory develops during the first two years of a baby's life.
- Conditions
- Not Applicable - Healthy Participants, Focus is the Memory System, Paediatric
- Trial name
- MEMRI (NCT07849075)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Paediatric Neuroimaging Research Group
Healthy
Study of 24-hour Intragastric pH Profiles of Esomeprazole 40 mg and Lansoprazole 30 mg in Healthy Volunteer Subjects
This study is intended to evaluate whether intravenous (iv) esomeprazole (Nexium® ) offers better intragastric acid suppression than iv lansoprazole (Prevacid ®
- Trial name
- NCT00230516
- Testing
- Nexium, Prevacid
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Not Applicable - Healthy Adult Participants
Study of XmAb412 in Healthy Participants
This Phase 1 Study will evaluate the safety, tolerability, pharmacokinectics and pharmacodynamics of XmAb412 in healthy adult participants
- Trial name
- NCT07713485
- Testing
- XmAb412 Monoclonal Bispecific Antibody
- Where
- 2 sites in Australia
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Xencor, Inc.
Bioavailability
A Study Investigating the Effects of Niagen™ in Healthy Adults.
This study will evaluate the effect of repeated doses of Niagen™ on Niagen™ metabolite concentrations in blood, urine and muscle. There will be 3 doses of Niagen™ compared to a placebo.
- Trial name
- 15NRHC (NCT02712593)
- Testing
- Niagen™ 100, Niagen™ 300, Niagen™ 1000
- Where
- Canada
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- KGK Science Inc.
Pharmacokinetics, Safety
Pharmacokinetics, Safety, and Tolerability of Intramuscular 5-MeO-DMT in Healthy Volunteers
The primary objective of the study is to assess the pharmacokinetics, safety, and tolerability of a single-dose and multiple-doses of 5-MeO-DMT administered by intramuscular (IM) injections in healthy subjects.
- Conditions
- Pharmacokinetics, Safety, Tolerability
- Trial name
- NCT05698095
- Testing
- 5-methoxy-N,N-dimethyltryptamine succinate salt
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Usona Institute
Healthy
Phase I Safety Study of Inhaled N-IP-00001 to Determine Tolerability and Safety in Healthy Volunteers.
Randomized, double-blind, placebo-controlled, dose-escalation Phase I safety study of inhaled N-IP-00001, to determine tolerability and safety in healthy volunteers.
- Trial name
- NCT06662019
- Testing
- N-IP-00001 inhalation solution, 0.9% NaCl isotonic saline solution
- Where
- 2 sites in Australia
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- NeoTrials Pty Ltd
Healthy Volunteers
Pharmacokinetics of GH001 Delivered Via a Proprietary Aerosol Delivery Device in Healthy Subjects
This is an open-label Phase 1 trial in healthy subjects designed to characterize the pharmacokinetic (PK) profile, pharmacodynamics, and safety and tolerability of GH001 (mebufotenin) delivered via the GH001 Aerosol Delivery…
- Trial name
- NCT06511947
- Testing
- 5 Methoxy N,N Dimethyltryptamine
- Where
- United Kingdom
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- GH Research Ireland Limited
N/A, as Healthy Volunteers
Study to Evaluate the Absorption, Distribution, Break Down and Elimination and the Safety of 14C-Labeled Tozadenant
The purpose of the study is to investigate how tozadenant is absorbed, distributed, broken down and eliminated from the body. The compound to be administered will be radiolabeled.
- Trial name
- NCT02240290
- Testing
- tozadenant tablet, C14-tozadenant capsule
- Where
- Netherlands
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Biotie Therapies Inc.
Hypertriglyceridemia
Effects of DHA-NAT on Postprandial Lipidaemia in Healthy Male Subjects
This study is an investigator-initiated, randomised, double-blind, placebo-controlled, cross-over human trial investigating the effect of DHA-NAT (C22:6 N-acyl taurine, an endogenous metabolite derived from the omega-3 fatty…
- Trial name
- FEAST (NCT05953064)
- Testing
- DHA-NAT
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gentofte, Copenhagen
HIV Infection
Safety and Immunogenicity of a Plasmid HIV Vaccine in HIV Uninfected Adults
The purpose of this study is to determine the safety and immune response to a investigational DNA Plasmid HIV vaccine, ADVAX e/g + ADVAX p/n-t (ADVAX), at three different dosage levels, in adults who are not infected with HIV.
- Trial name
- C001 (NCT00249106)
- Testing
- ADVAX
- Where
- 2 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- International AIDS Vaccine Initiative
N/A - Healthy Subjects
Engaging College Students in Developing and Testing a Video-based Intervention for HPV Vaccination Promotion
HPV vaccines offer hope against HPV-associated cancers for males and females; however, the rate of vaccination has not reached projected public health goals.
- Trial name
- HPV videos (NCT06397378)
- Testing
- short videos related to HPV and the HPV vaccine, CDC HPV Fact Sheet
- Where
- United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Michigan State University