Clinical trials: NAD
NAD
Nicotinamide Riboside Impact on Extracellular Nicotinamide Adenine Dinucleotide (NAD+)
The investigation is a clinical study in which the impact of taking the dietary supplement nicotinamide riboside (NR) on the concentration of extracellular nicotinamide adenine dinucleotide (eNAD+) in human plasma over time will…
- Trial name
- NICE (NCT06005350)
- Testing
- Niagen
- Where
- Germany
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Mild Cognitive Impairment, NAD
The Effects of Nicotinamide Adenine Dinucleotide (NAD) on Brain Function and Cognition
The purpose of this study is to determine the effects of Niagen (nicotinamide riboside, vitamin B3), on NAD levels, brain function including cognition and blood flow in people diagnosed with mild cognitive impairment (MCI).
- Trial name
- NAD (NCT02942888)
- Testing
- Nicotinamide riboside, Sugar Pill
- Where
- 2 sites in United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Cognitive Change, Inflammation
NAD+ Oral Supplement Pilot Intervention in Adult Females
The goal of this clinical trial is to learn whether Nicotinamide adenine dinucleotide (NAD+) can influence cognition and biomarkers in healthy, cognitively intact women aged 40-80.
- Conditions
- Cognitive Change, Inflammation, Neurodegenerative Diseases
- Trial name
- NCT06579209
- Testing
- Treatment
- Where
- 2 sites in United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of Rhode Island
Overweight and Obesity, Aging
NR Supplementation and Exercise
The number of age-related chronic diseases (like obesity, type 2 diabetes and cardiovascular diseases) is increasing rapidly worldwide, reaching pandemic proportions.
- Conditions
- Overweight and Obesity, Aging, Type 2 Diabetes
- Trial name
- NCT04907110
- Testing
- Niagen, Exercise
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Healthy Elderly Volunteers
Effects of Vitamin B3 Derivative Nicotinamide Riboside (NR) in Bone, Skeletal Muscle and Metabolic Functions in Aging
Researchers are trying to determine if the vitamin B3 derivative Nicotinamide Riboside (NR) has any effects in bone, skeletal muscle, and metabolic functions and structure in aging.
- Trial name
- NCT03818802
- Testing
- Nicotinamide Riboside
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Healthy Adult
Nicotinamide Riboside, Vit B3 Analogue, and Brain Energy Metabolism
The goal of this clinical trial is to learn how nicotinamide riboside (NR), a form of vitamin B3, affects brain energy metabolism in healthy adults.
- Trial name
- NCT07649161
- Testing
- Niagen®
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Heat Strain, Healthy Volunteer Study
The Kidney's Response to Exercise in Heat, and the Impact of Vitamin B3 on This Response
The goal of this clinical trial is to learn about the processes occurring in the kidneys while under heat stress in healthy volunteers.
- Conditions
- Heat Strain, Healthy Volunteer Study, Kidney Dysfunction
- Trial name
- NCT06983730
- Testing
- Vitamin B3
- Where
- 2 sites in United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Healthy
NAD-brain: a Pharmacokinetic Study of NAD Replenishment Therapy
The objective of the NAD-brain study is to determine the blood and brain pharmacokinetics of NAD replenishment therapy (NRT) using Nicotinamide Riboside (NR) or Nicotinamide Mononucleotide (NMN).
- Trial name
- NAD-brain (NCT05698771)
- Testing
- Nicotinamide Riboside (NR), nicotinamide mononucleotide
- Where
- Norway
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Sarcopenia, Nicotinamide Adenine Dinucleotide Concentration
Impacts of Nicotinamide Riboside on Functional Capacity and Muscle Physiology in Older Veterans
Frailty is an age-associated clinical condition of poor physiological reserve that increases risks for falls, hospitalization and mortality.
- Conditions
- Sarcopenia, Nicotinamide Adenine Dinucleotide Concentration, Muscle Quality and NAD+ Content
- Trial name
- NR-VET (NCT04691986)
- Testing
- Nicotinamide Riboside
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development