Clinical trials: NAsal MEthicillin-resistant Staphylococcus
Thoracic Surgery
PCR Technique to Identify Methicillin-sensitive and Methicillin-resistant Staphylococcus Aureus in Nasal and Respiratory Tract Samples
In patients on mechanical ventilation, it is not known whether the identification of S. aureus in LRT samples improves the performance of its nasal detection.
- Trial name
- NCT02640001
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Emilio Bouza
NAsal MEthicillin-resistant Staphylococcus
Prevalence of Multi-Drug Resistant Bacteria in Long-term Care Facilities
Antimicrobial resistance (AMR) is recognized as one of the major threats to global health [1], causing up to 25.000 deaths in the European Union every year, longer hospitalizations and increased healthcare costs.
- Trial name
- PreMDRinLTCF (NCT07234734)
- Where
- Italy
- Volunteers
- 581 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
MRSA Colonization
Evaluation of the Efficacy of Bio-K+ Cl-1285® In the Nasal Decolonization of Methicillin Resistant Staphylococcus Aureus (MRSA) Carrier Patients
Trial Objectives: Primary objective: To evaluate the efficacy of Bio-K+CL1285® in patients with Methicillin-Resistant S. aureus (MRSA) nasal colonization by comparing the MRSA decolonization following either Bio-K+CL1285® or…
- Trial name
- MRSA (NCT00941356)
- Testing
- Bio-K+ CL1285
- Where
- Canada
- Sponsor
- Bio-K Plus International Inc.
Methicillin Resistant Staphylococcus Aureus
Antibiotics Use and Carriage of Methicillin-resistant Staphylococci in Community Patients
In this prospective, observational, multicentric open study, the investigators will compare the acquisition rates of methicillin-resistant staphylococci (coagulase-negative staphylococci and Staphylococcus aureus) nasal carriage…
- Trial name
- StaphMRG (NCT01489878)
- Where
- France
- Volunteers
- 571 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Healthcare Associated Infections, Methicillin Resistant Staphylococcus Aureus
Active Bathing to Eliminate Infection (ABATE Infection) Trial
The ABATE Infection Project is a cluster randomized trial of hospitals to compare two quality improvement strategies to reduce multi-drug resistant organisms and healthcare-associated infections in non-critical care units.
- Conditions
- Healthcare Associated Infections, Methicillin Resistant Staphylococcus Aureus, Multi Drug Resistant Organisms
- Trial name
- ABATE (NCT02063867)
- Testing
- Arm 2: Decolonization
- Where
- 52 sites in United States
- Volunteers
- 53 people
- Sponsor
- University of California, Irvine
Nasal Colonization With MRSA Bacteria
Microbiological Characterization and Nasal Carriage Rates of Methicillin Resistant Staphylococcus Aureus (MRSA) in Vancouver Downtown Eastside
We plan to compare data from 300 nasal swab in Vancouver's Downtown Eastside taken in 2001 to data obtained in 2005. The nasal carriage rate of MRSA and the specific characteristic of each MRSA found will be analyzed.
- Trial name
- NCT00247871
- Where
- Canada
- Volunteers
- 600 people
- Sponsor
- University of British Columbia
Nasal Carriers MRSA
A Phase I/IIa Study to Evaluate the Safety, Tolerability and Efficacy of Topical LTX-109 in Subjects Nasally Colonized With Methicillin-resistant/-Sensitive Staphylococcus Aureus (MRSA/MSSA)
This is a pilot study conducted to evaluate the safety, local tolerability and efficacy of LTX-109(Lytixar™), a lytic peptide designed to kill bacterias quickly and efficient.
- Trial name
- NCT01158235
- Testing
- LTX-109
- Where
- Sweden
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Lytix Biopharma AS
Methicillin-Resistant Staphylococcus Aureus
Retapamulin for Reducing MRSA Nasal Carriage
The investigators will conduct a randomized placebo-controlled double-blinded study of nasal decolonization with retapamulin vs.
- Trial name
- NCT01461668
- Testing
- Retapamulin
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- University of California, Irvine
Methicillin-resistant Staphylococcus Aureus
Efficacy Study of Altabax to Clear Methicillin-resistant Staphylococcus Aureus (MRSA) Nasal Colonization
The purpose of the study is to determine whether Altabax (retapamulin ointment, 1%) is effective in the treatment of methicillin-resistant Staphylococcus aureus (MRSA) nasal colonization.
- Trial name
- NCT00856089
- Testing
- Retapamulin
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Ochsner Health System
NAsal MEthicillin-resistant Staphylococcus
NAsal MEthicillin-resistant Staphylococcus (NAMES): a Prospective Study to Assess the Impact of Antibiotic Therapy on Nasal Colonization with Methicillin-resistant Staphylococcus Aureus (MRSA) Inhospitalized Children
Antimicrobial resistance (AMR) is recognized as one of the major threats to global health [1], causing up to 25.000 deaths in the European Union every year, longer hospitalizations and increased healthcare costs.
- Trial name
- NAMES (NCT06872099)
- Where
- Italy
- Volunteers
- 76 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
MRSA Colonization
Incidence of Methicillin Resistant Staphylococcus Aureus (MRSA) Carriage Rates in Resident Physicians
One hundred new residents will be recruited prior to the start of residency and followed prospectively for a year. Monthly nasal swabs will be performed to identify colonization with methicillin resistant staphylococcus aureus…
- Trial name
- NCT00929435
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Methicillin Resistant Staphylococcus Aureus Skin Infections
A Randomized Clinical Trial to Prevent Recurrent CA-MRSA Infection
This clinical trial tests the hypotheses that 1) body decolonization of patients with recurrent community-associated (CA) MRSA infections and their household members and 2) environmental decolonization of the patients' households…
- Trial name
- PRIMO (NCT00560599)
- Testing
- mupirocin and chlorhexidine, household cleaning and disinfection, mupirocin, chlorhexidine, & household cleaning/disinfection
- Where
- 6 sites in United States
- Volunteers
- 350 people
- Sponsor
- loren g miller
MRSA
Retapamulin as a Decolonizing Agent for MRSA
The purpose of this study is to investigate the efficacy of retapamulin to reduce carriage of MRSA via a randomized, double-blind, placebo-controlled clinical study testing retapamulin among patients with confirmed…
- Trial name
- NCT03304873
- Testing
- Retapamulin
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- NYU Langone Health
Methicillin Resistant Staphylococcus Aureus Skin Infections
A Prospective Trial of Nasal Mupirocin, Hexachlorophene Body Wash, and Systemic Antibiotics for Prevention of Recurrent Methicillin Resistant Staphylococcus Aureus Infections
This clinical trial tests the hypothesis that body decolonization of patients with recurrent community-associated (CA) MRSA infections will significantly reduce the likelihood of recurrent CA-MRSA infection.
- Trial name
- NCT01049438
- Testing
- nasal mupirocin, topical 3% hexachlorophene body wash, oral anti-MRSA antibiotic
- Volunteers
- 31 people
- Sponsor
- Natividad Medical Center
Staphylococcus Aureus
A Prospective Cohort Pilot Study of the Clinical and Molecular Epidemiology of Staphylococcus Aureus in Pregnant Women at the Time of Group B Streptococcal Screening in a Large Urban Medical Center in Chicago, IL USA
Background: Community acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) is an emerging pathogen of the 21st century whose incidence as a cause of local and invasive infections has significantly increased, especially…
- Trial name
- NCT00532324
- Testing
- CA-MRSA Decolonization
- Where
- United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Staphylococcus Aureus, Methicillin-resistant Staphylococcus Aureus
Volatile Organic Compounds in Staphylococcus Aureus Patients
The zNose® MRSA test is a non-invasive breath test for markers of Staphylococcus aureus, which may predict the probability of bacterial organisms in the anterior nares, throat and respiratory tract, wounds, and anus and therefore…
- Conditions
- Staphylococcus Aureus, Methicillin-resistant Staphylococcus Aureus, Nosocomial Disease
- Trial name
- MRSAVOC (NCT01379053)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Landon Pediatric Foundation
Surgical Wound Infection, Preoperative Care
Povidone-Iodine for Nasal Decolonization
To evaluate the efficacy and tolerability of 10% povidone-iodine in eliminating nasal carriage of Staphylococcus aureus and MRSA.
- Conditions
- Surgical Wound Infection, Preoperative Care, Methicillin-Resistant Staphylococcus Aureus
- Trial name
- NCT05529173
- Testing
- Povidone-Iodine 10%, 0.9% NaCl Solution
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- Rutgers, The State University of New Jersey