Clinical trials: NEC - Necrotizing Enterocolitis
NEC, NEC - Necrotizing Enterocolitis
Assessing the Efficacy of Probiotics in Prevention of NEC in Preterm Babies
The goal of the study is to check efficacy of probiotics in preventing necrotizing enterocolitis. The main questions would be if the preterm baby developed NEC or not.
- Trial name
- NCT07233382
- Testing
- Probiotic, 10% dextrose
- Where
- Pakistan
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Hayatabad Medical Complex
Necrotizing Enterocolitis (NEC), Healthy Control
Predictive Diagnosis of Ulcero-Necrotizing EnteroColitis in Premature Babies Using an Artificial Intelligence Approach Based on Early Analysis of the Fecal Microbiota
Prematurity affects around 7% of births in France. Necrotizing enterocolitis (NEC) is a dreaded digestive complication. It is responsible for a mortality rate ranging from 15 to 40%, a rate that has remained stable in recent…
- Trial name
- PECUNIA (NCT06727877)
- Testing
- Ability of early digestive microbiota analysis (using artificial intelligence) to predict the occurrence of NEC diagnosed according to the Bell classification.
- Where
- 5 sites in France
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Necrotizing Enterocolitis (NEC)
NETs: Protection or Harm in Neonatal Inflammation or Infection
This is a prospective in vitro cell biology study of polymorphonuclear leukocyte (PMN) protein synthesis in response to PAF. PMNs from cord blood of premature human infants at risk for NEC (birth weight between 501 - 1500 grams)…
- Trial name
- NCT00747851
- Where
- United States
- Volunteers
- 388 people, healthy volunteers welcome
- Sponsor
- University of Utah
Instrumental Delivery, NEC, Affecting Fetus or Newborn
PROPENSITY-ID: Sonographic and Clinical Assessment of Head Position Prior to Instrumental Delivery and Labour Outcomes
Instrumental delivery is performed in 3-15% of all births (1). Successful instrumental delivery avoids need for cesarean section with associated maternal surgical morbidity, risk from neonatal disimpaction and future pregnancy…
- Conditions
- Instrumental Delivery, NEC, Affecting Fetus or Newborn, Second Stage Cesarean Delivery, Occiput Position
- Trial name
- PROPENSITYID (NCT05557097)
- Testing
- Intrapartum sonography
- Where
- Italy
- Volunteers
- 2,282 people, healthy volunteers welcome
- Sponsor
- University of Parma
Premature Birth, NEC
Prenatal Administration of Spermine Promotes Maturation of Premature Fetal Gut Epithelial Tight Junction: Experimental Study on Fetal Rabbit
Infections, particularly on the gastrointestinal tract, has been known to be one of the leading causes of death in preterm infants. This is due to the immaturity of the intestinal epithelial cells.
- Trial name
- NCT04004091
- Testing
- Spermine
- Where
- Indonesia
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- dr. Riana Pauline Tamba, SpB(K)BA