Clinical trials: NERVES
Carpal Tunnel Syndrome
The Evaluation for Fu's Subcutaneous Needling (FSN) in Carpal Tunnel Syndrome.
The goal of this clinical trial is to evaluate the efficacy of Fu's Subcutaneous Needling (FSN) in carpal tunnel syndrome (CTS).
- Trial name
- NCT05627349
- Testing
- wrist splinting, FSN
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Postoperative Pain
Efficacy of Modified Thoracoabdominal Nerves Block Through Perichondrial Approach in Total Laparoscopic Hysterectomies
TAPA is a new analgesic block technique that involves the injection of local anesthetics into the thoracoabdominal nerves using a perichondrial approach.
- Trial name
- NCT06116409
- Testing
- Bupivacain
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Optic Neuritis, Multiple Sclerosis
Post-COntrast 3D SE T1 Versus Coronal SE T1-WI MRI in Detecting Optic Neuritis (COCON)
3D FLAIR, 3D T1 FAT SAT, coronal T2 and coronal T1 dixon sequences were usually used to assess visual deficits in MRI. Optic nerve examination is preferably performed using a coronal T2 sequence in order to detect a hypersignal…
- Trial name
- COCON (NCT04793087)
- Testing
- Magnetic Resonance Imaging
- Where
- France
- Volunteers
- 1,200 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Carpal Tunnel Syndrome
Comparison of Efficacy Between Conservative Versus Operative Management of Carpel Tunnel Syndrome
Patients presented with symptoms of numbness at night, pain, or tingling sensation in the fingers particularly at night diagnosed by consultant orthopedic surgeon on physical examination.
- Trial name
- NCT06060314
- Testing
- Conservative Approach, Surgical Approach
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Combined Military Hospital Abbottabad
Neuroendocrine Tumors, Prostate Cancer
Dynamic Whole Body Positron Emission Tomography/Computed Tomography Imaging
Quantitative parameters obtained with dynamic whole body imaging using positron emission tomography (PET) can provide additional and complementary information to standard PET.
- Conditions
- Neuroendocrine Tumors, Prostate Cancer, Prostatic Neoplasms, Carcinoid Tumor
- Trial name
- NCT04017104
- Testing
- 18F-FDG PET/CT, 68Ga-DOTATOC PET/CT, 18F-DCFPyL PET/CT
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- British Columbia Cancer Agency
Brain Tumor, Recurrent, Brain Tumor
Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles)
The objectives of this registry study are to evaluate real-world clinical outcomes and patient reported outcomes that measure the effectiveness and safety of STaRT.
- Conditions
- Brain Tumor, Recurrent, Brain Tumor, Brain Tumor, Primary, Brain Tumor - Metastatic
- Trial name
- NCT04427384
- Testing
- GammaTile
- Where
- 54 sites in United States
- Volunteers
- 600 people
- Sponsor
- GT Medical Technologies, Inc.
Glioblastoma
Key Longitudinal Associations With Risk and Glioblastoma Outcomes
The goal of this observational study is to find out what factors affect the health and risks in adults with glioblastoma (GBM), a grade 4 brain cancer.
- Trial name
- Key LARGO (NCT06625684)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Duke University
Post-COVID-19 Condition, Ulcerative Colitis
Emerging Indications for Hyperbaric Oxygen Treatment
This study will evaluate the effectiveness of hyperbaric oxygen therapy (HBOT) on treating emerging indications (i.e., conditions that have shown to potentially benefit from HBOT) using the Multicenter Registry for Hyperbaric…
- Conditions
- Post-COVID-19 Condition, Ulcerative Colitis, Crohn Disease, Calciphylaxis
- Trial name
- NCT07240649
- Testing
- Hyperbaric oxygen treatment (HBOT), 100% Oxygen
- Volunteers
- 100 people
- Sponsor
- Jay C. Buckey Jr.
Implant Site Reaction
Neurosensory Disturbances After Inferior Alveolar Nerve Lateralization
Evaluation of the neurosensory disturbances after inferior alveolar nerve lateralization with and without isolation of the simultaneously placed implants using collagen membrane And measuring the stability of implants after…
- Trial name
- NCT03664219
- Testing
- isolation of IAN from implant with collagen membrane
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Cairo University
Inguinal Hernia, Postoperative Pain
Ultrasound-Guided Ilioinguinal-Iliohypogastric Nerve Block Following Spinal Anesthesia Comparing Dexmedetomidine Versus Nalbuphine as Adjuvants to Bupivacaine in Unilateral Inguinal Hernia Repair
This study evaluates and compares the pain-relieving efficacy and safety of adding either dexmedetomidine or nalbuphine to bupivacaine in an ultrasound-guided ilioinguinal-iliohypogastric nerve block for patients undergoing…
- Trial name
- NCT07837492
- Testing
- Bupivacaine, Nalbuphine, Dexmedetomidine
- Volunteers
- 102 people
- Sponsor
- Assiut University
High Grade Glioma
Study to Evaluate 5-ALA Combined With CV01 Delivery of Ultrasound in Recurrent High Grade Glioma
A Phase 1 Multi-center clinical Trial Evaluating the Safety and Tolerability of 5-aminolevulinic Acid (5-ALA) Combined With CV01 Delivery of Ultrasound for Sonodynamic Therapy (SDT) in Patients With recurrent High Grade Glioma…
- Trial name
- NCT05362409
- Testing
- 5 Aminolevulinic Acid, CV01-delivered ultrasound
- Where
- 3 sites in United States
- Volunteers
- 22 people
- Sponsor
- Alpheus Medical, Inc.
Osteoarthritis (OA) of the Hip
PENG Block & PENG PRF
The primary aim of this study is to prospectively compare the effects of the pericapsular nerve group (PENG) block alone and the combination of PENG block with pulsed radiofrequency (PRF) on pain intensity in patients with…
- Trial name
- PENG-PRF (NCT07360093)
- Testing
- PENG Block Pulsed radiofrequency
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Ankara City Hospital Bilkent
Localized Resectable Neuroblastoma, Localized Unresectable Neuroblastoma
Cyclophosphamide and Prednisone With or Without Immunoglobulin in Treating Abnormal Muscle Movement in Children With Neuroblastoma
This randomized phase III trial is studying cyclophosphamide, prednisone, and immunoglobulin to see how well they work compared to cyclophosphamide and prednisone alone in treating patients with abnormal trunk muscle movements…
- Conditions
- Localized Resectable Neuroblastoma, Localized Unresectable Neuroblastoma, Regional Neuroblastoma, Stage 4 Neuroblastoma
- Trial name
- NCT00033293
- Testing
- Clinical Observation, Cyclophosphamide, Laboratory Biomarker Analysis
- Where
- 104 sites in United States, Australia and 1 more
- Volunteers
- 53 people
- Sponsor
- Children's Oncology Group
Melanoma
The Effects of Vemurafenib + Cobimetinib on Immunity in Patients With Melanoma
This study is for patients with malignant melanoma which has spread beyond the local area and cannot be surgically removed, and who have melanoma tumors that are accessible for repeat biopsies.
- Trial name
- NCT01813214
- Testing
- Vemurafenib, Cobimetinib
- Where
- 4 sites in United States
- Volunteers
- 5 people
- Sponsor
- Georgetown University
Cancer
Suberoylanilide Hydroxamic Acid in Treating Patients With Advanced Cancer
RATIONALE: Suberoylanilide hydroxamic acid may stop the growth of cancer cells by blocking the enzymes necessary for cancer cell growth.
- Trial name
- NCT00045006
- Testing
- vorinostat
- Where
- United States
- Sponsor
- Memorial Sloan Kettering Cancer Center
Vertebral Compression Fracture, Facet Joint Pain
Radiofrequency Ablation: Treatment for Posterior Element Pain From Vertebral Compression Fractures
The purpose of this study is to test the efficacy of radiofrequency ablation of the medial branch nerves (RFA-MBN) in relieving pain and improving physical function in patients with subacute and chronic vertebral compression…
- Trial name
- NCT03651804
- Testing
- Radiofrequency ablation of the medial branch nerves, Non-steroidal anti-inflammatory drugs, Bisphosphonates
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Davis
Leprosy Neuropathy
Low Level Laser Therapy Effects in Peripheral Nerves Patient With Leprosy.
We are going to investigate leprosy patients with neuropathies. This problem can lead to changes in nerve function and lead to disability.
- Trial name
- NCT03072004
- Testing
- LLLT
- Where
- Brazil
- Volunteers
- 92 people
- Sponsor
- Federal University of Uberlandia
Advanced Solid Tumors
Study to Evaluate Adverse Events, Change in Disease Activity, and How ABBV-706 Moves Through the Body When Intravenously (IV) Infused Alone or in Combination With IV Infused Budigalimab, Cisplatin, or Carboplatin in Adult Participants With Advanced Solid Tumors
Cancer is a condition where cells in a specific part of body grow and reproduce uncontrollably. The purpose of this study is to assess safety, tolerability, pharmacokinetics and preliminary efficacy of ABBV-706 as a monotherapy…
- Trial name
- NCT05599984
- Testing
- ABBV-706, Cisplatin, Budigalimab
- Where
- 66 sites in United States, Australia and 8 more
- Volunteers
- 288 people
- Sponsor
- AbbVie
Shoulder Arthroscopic Surgery
Is Pericapsular Nerve Group Block Better Than Interscalene Nerve Block Regarding Effect on Hand Movement in Shoulder Scope Surgeries?
The goal of this clinical trial is to learn if pericapsular nerve group block (PENG) in shoulder scope surgery provides adequate analgesia with less affection of muscle power compared to interscalene block.
- Trial name
- PENG (NCT07057947)
- Testing
- Pericapsular Nerve Group (PENG) Block, Interscalene Nerve Block, Acuson X300 ultrasound,Siemens medical solution INC, Germany
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Sherin Refaat
Melanoma, Non Small Cell Lung Cancer
Identifying the Predictive Factors of Response to PD-1 or PD-L1 Antagonists
This is a prospective cohort study which aims to identify predictive factors of response to PD-1 and PD L1 antagonists authorised for use in France in treatment of melanoma, NSCLC, or HNSCC.
- Conditions
- Melanoma, Non Small Cell Lung Cancer, Head and Neck Squamous Cell Carcinoma
- Trial name
- CHECK'UP (NCT03412058)
- Testing
- Biopsy
- Where
- 19 sites in France
- Volunteers
- 152 people
- Sponsor
- UNICANCER
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