Clinical trials: NERVES
Auditory; Nerve
Auditory Intranerve Stimulation Study
This feasibility clinical investigation is designed to answer the question of whether auditory brainstem responses can be safely elicited by acute electrical stimulation within the human auditory nerve.
- Trial name
- AIS (NCT06306534)
- Testing
- Auditory Nerve Acute (ANA) Electrode Array
- Where
- Germany
- Volunteers
- 10 people
- Sponsor
- Hannover Medical School
Phrenic Nerve Injury
Modified Diaphragmatic Plication Rectifies Dyspnea
Traditional diaphragmatic plication (DP) surgery is employed to ameliorate respiratory function in patients with diaphragmatic paralysis, which is rather complicated. This study introduces a modified method of DP.
- Trial name
- NCT06775873
- Testing
- Modified diaphragmatic plication
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Tongji University
Knee Arthroplasty, Total, Peripheral Nerve Block
Postoperative Analgesia in Bilateral Knee Arthroplasties
To observationally compare the analgesic efficacy of LIA and S-FICB techniques and to record the pain scores of patients who underwent bilateral knee operations in the postoperative period.
- Conditions
- Knee Arthroplasty, Total, Peripheral Nerve Block, Pain, Postoperative
- Trial name
- NCT06357013
- Testing
- Bilateral Suprainguinal fascia iliaca compartment block, Local infiltration analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kocaeli City Hospital
Anterior Glenoid Nerve Block, Pericapsular Nerve Group Block
Anterior Glenoid Nerve Block Versus Pericapsular Nerve Group Block Versus Interscalene Brachial Plexus Block for Postoperative Pain Management in Shoulder Arthroscopic Surgeries
This study aims to compare between Anterior glenoid nerve block, pericapsular nerve group (PENG) block and Interscalene brachial plexus (ISB) block for post-operative pain management in shoulder arthroscopic surgeries
- Conditions
- Anterior Glenoid Nerve Block, Pericapsular Nerve Group Block, Interscalene Brachial Plexus Block, Postoperative Pain
- Trial name
- NCT06765278
- Testing
- Interscalene brachial plexus block, Anterior glenoid nerve block, Pericapsular nerve group block
- Where
- Egypt
- Volunteers
- 49 people
- Sponsor
- Ain Shams University
Symptomatic Neuroma, Morton's Neuroma
Study of AxoGuard® Nerve Cap and Neurectomy for Treatment of Symptomatic Neuroma & Prevention of Recurrent Neuroma Pain
Comparing safety, pain, user experience, healthcare economic costs, work productivity, impairment and quality of life outcomes between Axoguard® Nerve Cap and neurectomy in the treatment of symptomatic neuromas in the foot or…
- Conditions
- Symptomatic Neuroma, Morton's Neuroma, Chronic Nerve Pain
- Trial name
- REPOSE (NCT03940963)
- Testing
- AxoGuard® Nerve Cap, Standard Neurectomy
- Where
- 11 sites in United States
- Volunteers
- 86 people
- Sponsor
- Axogen Corporation
Residual Limb Pain, Amputation Neuroma
Surgical Treatments for Postamputation Pain
This is a double-blind randomised controlled trial (RCT) which compares the effectiveness of three surgical techniques for alleviating residual limb pain (RLP), neuroma pain and phantom limb pain (PLP).
- Conditions
- Residual Limb Pain, Amputation Neuroma, Phantom Limb Pain, Pain, Neuropathic
- Trial name
- NCT05009394
- Testing
- Targeted Muscle Reinnervation (TMR), Regenerative Peripheral Nerve Interface (RPNI), Standard neuroma treatment, neuroma excision, and muscle burying
- Where
- 9 sites in United States, Australia and 5 more
- Volunteers
- 110 people
- Sponsor
- Prometei Pain Rehabilitation Center
Optic Nerve Sheath Diameter Measurements for Carotis Endarterectomy
Can Optic Nerve Sheath Diameter Detect Norological Morbidities for Patients Undergoing Carotis Endarterectomy
The main purpose of this study is to investigate the contribution of changes in Optic Nerve Sheath Diameter (OSNC) measured at different periods during Carotid Endarterectomy (CEA) operations to the prediction of neurological…
- Trial name
- NCT06491693
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Neurofibromatosis Type 1, Recurrent Childhood Pilocytic Astrocytoma
Low-Dose or High-Dose Lenalidomide in Treating Younger Patients With Recurrent, Refractory, or Progressive Pilocytic Astrocytoma or Optic Pathway Glioma
This randomized phase II trial studies how well low-dose lenalidomide works compared with high-dose lenalidomide in treating younger patients with juvenile pilocytic astrocytomas or optic nerve pathway gliomas that have come back…
- Conditions
- Neurofibromatosis Type 1, Recurrent Childhood Pilocytic Astrocytoma, Recurrent Childhood Visual Pathway Glioma
- Trial name
- NCT01553149
- Testing
- Lenalidomide, Pharmacological Study
- Where
- 126 sites in United States, Australia and 2 more
- Volunteers
- 75 people
- Sponsor
- National Cancer Institute (NCI)
Breast Cancer Surgery, Breast Conserving Surgery
Erector Spinae Plane Block vs. PECS I-II Blocks After Breast-conserving Surgery
The goal of this study is to compare the analgesic effects of ESPB and PECS II blocks in patients undergoing BCS. The main question it aims to answer is: Whether these two different block procedures will create a difference in…
- Conditions
- Breast Cancer Surgery, Breast Conserving Surgery, Erector Spinae Plane Block, Pectoral Nerve (PECS) Block
- Trial name
- NCT06758765
- Testing
- Erector Spinae Plane Block, Pectoral Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Istanbul Saglik Bilimleri University
Conventional Radiofrequency Thermocoagulation Application to the Articular Branches of the Femoral and Obturator Nerve, Chronic Hip Pain
Long-Term Follow-up of Radiofrequency to Articular Branches of the Femoral and Obturator Nerve in Chronic Hip Pain
It has been observed that the deterioration in the physical performance of the hip, the medical need before the specialist consultation and the deterioration in the health status can progress treatment[3].
- Trial name
- NCT06751472
- Testing
- VPS (Verbal Pain Score), WOMAC (Western Ontario and McMaster Universities Arthritis Index) scale
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Aydin Adnan Menderes University
Suprascapular Nerve, Shoulder Impingement Syndrome
The Clinical Efficacy of Different Durations of Suprascapular Nerve Pulsed Radiofrequency
Chronic shoulder pain due to impingement syndrome and supraspinatus tendinosis is a debilitating condition. Suprascapular nerve innervates most part of shoulder joint.
- Conditions
- Suprascapular Nerve, Shoulder Impingement Syndrome, Pulsed Radiofrequency, Chronic Pain
- Trial name
- NCT06713005
- Testing
- suprascapular nerve block and 4 mins Pulsed radiofreuency application to suprascapular nerve, suprascapular nerve block and 9 mins Pulsed radiofreuency application to suprascapular nerve
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Ankara University
Abdominal Pain, Abdominal Cutaneous Nerve Entrapment Syndrome
Abdominal Cutaneous Nerve Entrapment Syndrome
Nerve entrapment as a cause of chronic abdominal pain is frequently overlooked. A series of nerves pass through the muscles of the abdomen before reaching the skin to carry sensations.
- Trial name
- ACNES (NCT03574727)
- Testing
- Injection to or release of anterior cutaneous nerves
- Where
- United Kingdom
- Volunteers
- 35 people
- Sponsor
- University of Aberdeen
Lumbar Facet Arthrosis, Nerve Degeneration
Nerve Composition of Human Lumbar Dorsal Primary Rami and Its Medial Branch
The purpose of the study is to understand the composition of the nerves supplying the facet joints in low back.
- Trial name
- NCT05091112
- Testing
- Spinal surgery, Histology
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Aberdeen
Total Hip Surgery, Pericapsular Nerve
Comparison of Pericapsular Nerve Group Block and Quadratus Lumborum Block
Adequate pain management following total hip arthroplasty (THA) is a key component for patient satisfaction and early ambulation.
- Conditions
- Total Hip Surgery, Pericapsular Nerve, Quadratus Lumborum
- Trial name
- NCT05654519
- Testing
- PENG/LFCN and QL Blocks
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Konya Necmettin Erbakan Üniversitesi
Diaphragmatic Paralysis, Anterior Suprascapular Nerve Block
Combined Anterior Suprascapular Nerve Block and Superficial Cervical Plexus Block In Shoulder Arthroplasty Surgery
The suprascapular nerve, originating from the C5 trunk, provides innervation to the acromioclavicular and glenohumeral joints. The supraclavicular nerve, a branch of the cervical plexus, contributes to the sensory innervation of…
- Conditions
- Diaphragmatic Paralysis, Anterior Suprascapular Nerve Block, Superficial Cervical Plexus Block, Phrenic Nerve Paralysis
- Trial name
- NCT06146179
- Where
- Turkey (Türkiye)
- Volunteers
- 8 people
- Sponsor
- Istanbul Medeniyet University
Vagus Nerve Stimulations
Comparison of the Acute Effects of Auricular Vagus Nerve Stimulation and Deep Breathing Exercise
The goal of this clinical trial is to investigate whether vagus stimulation and breathing exercises are more effective in healthy adults.
- Trial name
- NCT06740032
- Testing
- Transcutaneous vagus nerve stimulation, Deep breath exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul Gelisim University
Hip Fractures, Ultrasound-guided Nerve Block
Fascia Iliaca Compartment Block and Tramadol for Analgesia in Hip Fracture
Hip fractures are a growing public health concern globally due to the aging population, with high incidence and significant mortality rates one year post-fracture.
- Conditions
- Hip Fractures, Ultrasound-guided Nerve Block, Perioperative Analgesia
- Trial name
- NCT06728033
- Testing
- supra-inguinal fascia iliaca compartment block, Tramadol
- Where
- China
- Volunteers
- 240 people
- Sponsor
- West China Hospital
Otolaryngological Diseases Requiring Mastoidectomy, Middle Ear Surgery, Endolymphatic Sac Surgery, Cochlear Implant, Labyrinthectomy, Petrous Apex Lesions, Facial Nerve Surgery, and Lateral Skull Base Tumors
AI Recognition of Important Structures in Otolaryngological Surgery
Developing a system for artificial intelligence to recognize anatomical landmarks in otolaryngological surgery, enabling real-time tracking of critical temporal bone structures during surgery.
- Trial name
- NCT06726551
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Scalp Nerve Block, Craniotomy Surgery
The Efficacy of Regional Scalp Block in Craniotomy
The objective of this clinical trial is to evaluate the role of scalp nerve block in craniotomy. The primary questions it seeks to answer are: What are the efficacy and safety profiles of scalp nerve block in craniotomy? The…
- Trial name
- NCT06720285
- Testing
- nerve block with 0.5% ropivacaine, General anesthesia and opioids (fentanyl, propofol, rocuronium)
- Where
- Indonesia
- Volunteers
- 40 people
- Sponsor
- Universitas Airlangga
Cubital Tunnel Syndrome, Nerve Compression
Promoting Healing of Nerves Through Electrical Stimulation
This study is evaluating a new therapeutic use of electrical stimulation to promote nerve healing and improve functional recovery following surgical intervention for nerve compression.
- Conditions
- Cubital Tunnel Syndrome, Nerve Compression, Nerve Injury, Ulnar Neuropathies
- Trial name
- PHONES (NCT04662320)
- Testing
- Checkpoint BEST System
- Where
- 5 sites in United States
- Volunteers
- 100 people
- Sponsor
- Checkpoint Surgical Inc.