Clinical trials: NERVES
Vagus Nerve Stimulation
Transauricular Vagal Nerve Stimulation Improves Postoperative Delirium in Elderly Patients
To investigate the efficacy and safety of perioperative Transauricular vagal nerve stimulation in improving Postoperative Delirium in elderly patients undergoing elective surgery Lay the groundwork for a Phase III study.
- Trial name
- Vnstar-IIa (NCT06421090)
- Testing
- Transauricular Vagal Nerve Stimulation
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Beijing Tiantan Hospital
Peroneal Nerve Entrapment
Follow-up and Outcome of Operative Treatment With Decompressive Release Of The Peroneal Nerve
The FOOT DROP trial is a prospective, multi-center, randomized controlled trial to assess if decompressive surgery for peroneal nerve entrapment is superior to maximal conservative treatment.
- Trial name
- FOOTDROP (NCT04695834)
- Testing
- Neurolysis peroneal nerve, Maximal physiotherapy
- Where
- 18 sites in Belgium, Netherlands
- Volunteers
- 182 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Neuropathy, Diabetic, Small Nerve Fiber Neuropathy
Characterization and Prediction of Early Onset Diabetic Peripheral Neuropathy
Predicting early onset neuropathy in people with type 1 diabetes
- Conditions
- Neuropathy, Diabetic, Small Nerve Fiber Neuropathy, Type 1 Diabetes
- Trial name
- NeuroPredict (NCT05546138)
- Testing
- Skin biopsies with quantification of intra-epidermal nerve fibre density, Perception Threshold Tracking, Thermal perception thresholds
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- Aalborg University Hospital
Optic Nerve Sheath Diameter
Changes of Optic Nerve Sheath Diameter Between Obese and Non-obese Patients Undergoing Laparoscopic Gynecological Surgery
This study aims to compare the change of optic nerve sheath diameter in obese and non-obese patients undergoing laparoscopic gynecological surgery in a steep Trendelenburg position.
- Trial name
- NCT04427085
- Testing
- Ultrasound assessment of optic nerve sheath diameter
- Where
- South Korea
- Volunteers
- 70 people
- Sponsor
- SMG-SNU Boramae Medical Center
Median Nerve Injury
Effects of Robotic Glove Hand Training in Patients After Median Nerve Transfer
Selective nerve transfers provide an opportunity for restoring the motor function after nerve injuries. Upper-limb robot-assisted therapy has been established as a safe and feasible treatment to complement rehabilitation after…
- Trial name
- NCT06459908
- Testing
- Robot Glove Hand Training, Conventional Hand Rehabilitation Exercises
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- Riphah International University
Foot Surgery, Ankle Surgery
Liposomal Bupivacaine With Dexamethasone for Foot Surgery
This study aims to understand the ideal formulation to utilize in saphenous nerve and popliteal nerve blocks for foot and ankle procedures.
- Conditions
- Foot Surgery, Ankle Surgery, Post Operative Pain, Popliteal Nerve Block
- Trial name
- NCT06465992
- Testing
- Exparel 266 MG Per 20 ML Injection, Bupivacaine Hcl 0.75% Inj, Dexamethasone
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Transcutaneous Electric Nerve Stimulation, Gambling
Brain Mechanism and Intervention of Executive-control Dysfunction Among Gambling Disorder
The investigators assume that transcranial Alternating Current Stimulation (tACS) could improve gambling disorder patients' executive-control function by adjusting the synchronization patterns and enhancing the functional…
- Trial name
- NCT06195995
- Testing
- Transcranial alternating current stimulation-true stimulus
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Shanghai Mental Health Center
Cold Hypersensitivity, Vascular System Injuries
Treatment of Frostbite Sequelae With Botulinum Toxin A
Background Digital vasospasm as part of frostbite sequelae is comparable to the vasospastic disorders found in Raynaud's phenomenon which has been successfully treated with Botulinum toxin type A injections in the palm of the…
- Conditions
- Cold Hypersensitivity, Vascular System Injuries, Vibration; Disorder, Sensory Disorders
- Trial name
- NCT06460194
- Testing
- Botuinum toxin
- Where
- Norway
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital of North Norway
Posterior Tibial Nerve Stmulation
Urinary Symptoms After Posterior Tibial Nerve Stimulation
Overactive bladder (OAB) is a common syndrome affecting 7 million people in France, very often of idiopathic origin. Current therapeutic management of OAB primarily involves hygiene and diet rules, patient education, behavioral…
- Trial name
- TENSI (NCT06458491)
- Testing
- Evolution of urinary symptoms
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Hospices Civils de Lyon
Hand Transplantation, Peripheral Nerve Injuries
Harnessing Neuroplasticity to Enhance Functional Recovery During Chronic Recovery From Upper Extremity Nerve Repair
This study adopts a strategy that has arisen from basic neuroscience research on facilitating adaptive brain plasticity and applies this to rehabilitation to improve functional recovery in peripheral nervous system injuries…
- Conditions
- Hand Transplantation, Peripheral Nerve Injuries, Neurologic Rehabilitation
- Trial name
- NCT03610763
- Testing
- Transcranial Direct Current Stimulation, Modified Constraint Induced Movement Therapy
- Where
- 3 sites in United States
- Volunteers
- 180 people
- Sponsor
- University of Missouri-Columbia
Safety and Efficacy, Scalp Nerve Block
Safety and Analgesic Efficacy of a Modified Auriculotemporal Nerve Block
1. Efficacy of a modified auriculotemporal nerve blockade for patients undergoing supratentorial craniotomy 2. Safety of a modified auriculotemporal nerve blockade for patients undergoing supratentorial craniotomy
- Trial name
- NCT05556889
- Testing
- a modified auriculotemporal nerve blockade, Traditional auriculotemporal nerve blockade
- Where
- China
- Volunteers
- 252 people
- Sponsor
- Tongji Hospital
Prostate Cancer, Nerve Sparing Prostatectomy
Pilot Study of VTI Doppler Probe Use to Identify Neurovascular Bundle During Prostate Surgery
This study is designed to evaluate the use of a disposable laparoscopic Doppler probe in robotic assisted prostatectomies. The Vascular Technology, Inc.
- Trial name
- NCT01794936
- Testing
- VTI Probe
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Columbia University
Carpal Tunnel Syndrome, Ulnar Nerve Compression
Objective Evaluation of the Scratch Collapse Test With Dynamometer, a Prospective Multicenter Trial.
Carpal tunnel syndrome and compression of the ulnar nerve at the elbow are common pathologies, which are treated surgically. Diagnosis is usually based on an electromyogram (EMG), as well as symptomatology, etiology of typical…
- Trial name
- NCT05989373
- Testing
- Scratch collapse test
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Clinique Saint Jean, France
Nerve Block, Transapical Beating-heart Septal Myectomy
Postoperative Pain for Patients After TA-BSM
To retrospectively analyze the intraoperative and postoperative status of patients with hypertrophic cardiomyopathy undergoing TA-BSM, and to estimate whether paravertebral nerve block can improve postoperative pain for these…
- Trial name
- NCT06433089
- Testing
- Thoracic paravertebral block
- Where
- China
- Volunteers
- 197 people
- Sponsor
- Wenlong Yao (101480)
Normal Values of Peripheral Nerves in Healthy Children
Ultrasonographic Reference Values for Peripheral Nerves in Children
The purpose of this clinical trial is to assess normal values of the cross-sectional area of peripheral nerves and nerve roots in children and adolescents between 2 and 18 years.
- Trial name
- NCT02570802
- Testing
- Ultrasonographic examination
- Where
- Switzerland
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Electroacupuncture, Acupuncture
Effect of Electroacupuncture on Sensitive Symptoms of Distal Diabetic Peripheral Neuropathy
This is a controlled clinical trial with the aim to study the effects of electroacupuncture on neuropathic pain reduction, quality of life and changes in sensory and motor nerve conduction velocity in patients with type 2…
- Conditions
- Electroacupuncture, Acupuncture, Diabetic Polyneuropathy, Diabetic Peripheral Neuropathy
- Trial name
- EA&DPN (NCT05521737)
- Testing
- Electroacupuncture
- Where
- Mexico
- Volunteers
- 200 people
- Sponsor
- Instituto Mexicano del Seguro Social
Parkinson's Disease
31P-MRS Imaging to Assess the Effects of CNM-Au8 on Impaired Neuronal Redox State in Parkinson's Disease
REPAIR-PD is a single-center open label pilot, sequential group, investigator and patient blinded study to assess the CNS metabolic effects, safety, pharmacokinetics, and pharmacodynamics of CNM-Au8 in patients who have been…
- Trial name
- REPAIR-PD (NCT03815916)
- Testing
- Gold Nanocrystals
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Clene Nanomedicine
Digital Nerve Injury
NeuraGen 3D Pilot Study
This is a 10-subject, 12-month follow-up, prospective, multi-center, open-label, single arm clinical trial designed to understand the initial performance characteristics and confirm the safety profile of the NeuraGen 3D Nerve…
- Trial name
- NCT05343143
- Testing
- NeuraGen 3D Nerve Guide Matrix
- Where
- 4 sites in United States
- Volunteers
- 1 people
- Sponsor
- Integra LifeSciences Corporation
Vagus Nerve Stimulation, Electromyography
The Effect of Auricular Vagus Nerve Stimulation on EEG and EMG Measurement in Healthy Persons
The investigators aimed to divide the healthy individuals aged between 18-45 years, included in our study, into three groups as bilateral, unilateral-right and unilateral-left Auricular Vagus Nerve Stimulation (VNS).
- Conditions
- Vagus Nerve Stimulation, Electromyography, Electroencephalography
- Trial name
- NCT05088135
- Testing
- Bilateral Auricular Vagus Nerve Stimulation will be performed with a device called VAGUSTIM., Unilateral-Right Auricular Vagus Nerve Stimulation will be performed with a device called VAGUSTIM., Unilateral-Left Auricular Vagus Nerve Stimulation will be performed with a device called VAGUSTIM.
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Istanbul Gelisim University
Muscle Pain, Joint Pain
Prevalence of Muscle and Nerve and Joint Pain
The purpose of the study is to provide adequate information about the percentage of the main tissue that causing pain in most common spinal disorders either it is muscular, nerve or joint in each spinal parts, that will provide…
- Conditions
- Muscle Pain, Joint Pain, Nerve Pain
- Trial name
- NCT06402448
- Testing
- muscle pain , joint pain and nerve pain.
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Hadeer Gomaa Ebraheem Aly