Clinical trials: NEUROLYSIS
Analgesia
Evaluation of T2, T3 Sympathectomy for Postmastectomy Pain Syndrome by Pulse Oximeter
The aim of the study is to compare the efficacy of T2, T3 sympathetic block using thermal radiofrequency versus chemical neurolysis in postmastectomy pain syndrome using perfusion index derived from pulse oximetry.
- Trial name
- NCT04953507
- Testing
- Thermal Radiofrequency, Chemical Neurolysis
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- National Cancer Institute, Egypt
Allergic Rhinitis, Chronic Rhinitis
Laser Posterior Nasal Nerve Neurolysis
This clinical trial aims to learn if laser posterior nasal nerve neurolysis can treat chronic rhinitis in adults. It will also learn about the safety of laser posterior nasal nerve neurolysis.
- Conditions
- Allergic Rhinitis, Chronic Rhinitis, Rhinorrhea, Sneezing
- Trial name
- LPN3 (NCT07050992)
- Testing
- Laser posterior nasal nerve neurolysis
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Chiayi Christian Hospital
Pain, Chronic
Intraoperative Versus CT Guided Celiac Plexus Neurolysis in Unresectable Pancreatic Cancer
Many studies had stated that the coeliac plexus neurolysis (CPN) is a safe and effective treatment method of pain associated with pancreatic cancer.
- Trial name
- NCT03770247
- Testing
- Intraoperative celiac plexus neurolysis, CT guided celiac plexus neurolysis
- Where
- Egypt
- Volunteers
- 76 people
- Sponsor
- Mansoura University
Upper Abdominal Malignancies, Upper Gastrointestinal Cancer
Comparison of CT-Guided Celiac Plexus Neurolysis and Pharmacotherapy
After enrolment, patients were randomly assigned to two groups by means of a lottery procedure, whereby each patient blindly chose one of two labelled slips, resulting in group assignment to receive.
- Trial name
- NCT07761650
- Testing
- CT-guided celiac plexus neurolysis, Standard pharmacotherapy
- Where
- Pakistan
- Volunteers
- 110 people
- Sponsor
- Mayo Hospital Lahore
Peroneal Nerve Entrapment
Follow-up and Outcome of Operative Treatment With Decompressive Release Of The Peroneal Nerve
The FOOT DROP trial is a prospective, multi-center, randomized controlled trial to assess if decompressive surgery for peroneal nerve entrapment is superior to maximal conservative treatment.
- Trial name
- FOOTDROP (NCT04695834)
- Testing
- Neurolysis peroneal nerve, Maximal physiotherapy
- Where
- 18 sites in Belgium, Netherlands
- Volunteers
- 182 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Pancreatic Neoplasms
Randomized Trial of EUS Neurolysis in Pancreas Cancer
This is a clinical trial to determine more effective methods of controlling the pain in pancreatic cancer. Although narcotic pain medication are effective, they have many side effects and are underutilized due to social stigma…
- Trial name
- NCT00279292
- Testing
- Celiac Plexus Neurolysis
- Where
- 2 sites in United States
- Volunteers
- 26 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Low Back Pain
Study Of The Efficacy Of Neurolysis In Functional Recovery From Chronic Nonspecific Low Back Pain
This is a prospective, randomized, double-blind, placebo-controlled study. In an initial phase, 100 patients with chronic low back pain will be included in this study.
- Trial name
- NCT01190033
- Testing
- Neurotome OFF, neurolysis
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- University of Sao Paulo
Pain Management
Comparative Study Between Conventional Radiofrequency Ablation vs Chemical Neurolysis of Ganglion Impar for Treatment of Chronic Non Cancer Related Coccydynia
Aim: compare effectiveness (satisfaction) and duration of pain relief between patients who perform the conventional thermal radiofrequency on the ganglion impar vs patients who perform the chemical neurolysis with alcohol in…
- Trial name
- NCT07247565
- Testing
- Radiofrequency ablation alone, Alcohol injection
- Where
- Egypt
- Volunteers
- 74 people
- Sponsor
- Ain Shams University
Pancreatic Cancer
EUS-CPN: A Retrospective Review
The purpose of this retrospective study is to measure the safety of EUS-CPN in patients that have undergone this procedure in the last decade.
- Trial name
- NCT00577564
- Where
- United States
- Sponsor
- Indiana University
Malignancy, Pain Management
Endoscopic Ultrasound Guided Coeliac Plexus Neurolysis for Cancer Pain
Many cancer patients suffer from intractable pain and which is often suboptimally controlled by even strong opioid analgesics. Coeliac plexus neurolysis (CPN) is procedure which intended to permanently destroy the nociceptive…
- Trial name
- NCT04801082
- Testing
- Alcohol injection, Radiofrequency Ablation
- Where
- Hong Kong
- Volunteers
- 54 people
- Sponsor
- The University of Hong Kong
Coccygodynia, Coccydynia
Comparison of Ganglion Impar Radiofrequency Ablation and Phenol Neurolysis Techniques for Chronic Coccydynia Treatment
Radiofrequency ablation and phenol neurolysis of the ganglion impar are methods used in cases unresponsive to medication, particularly in patients who derive short-term or partial relief from the initial ganglion impar block.
- Trial name
- NCT07021365
- Testing
- Phenol Injection, Radiofrequency ablation alone
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Marmara University
Knee Osteoarthritis
Evaluation of Radiofrequency Neurolysis and Chemical Neurolysis of the Genicular Nerves
Knee osteoarthritis is one of the most common causes of pain and loss of function in the elderly population and is a source of socioeconomic costs.
- Trial name
- NCT05340166
- Testing
- Genicular nerve radiofrequency neurolysis, Genicular nerve chemical neurolysis
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Diskapi Teaching and Research Hospital
Chronic Calcific Pancreatitis
Intraoperative Coeliac Plexus Alcohol Neurolysis Along With Frey's Procedure for a Better Pain Relief
To study the effect of Intra operative Coeliac plexus alcohol neurolysis combined with Frey's procedure for effective pain relief in patients with Chronic Calcific Pancreatitis in a single centre setting with a Randomized…
- Trial name
- INFARCT (NCT02735330)
- Testing
- celiac plexus neurolysis using absolute alcohol, Frey's procedure
- Volunteers
- 136 people
- Sponsor
- Madras Medical College
Cancer Pain
Coeliac Plexus Neurolysis Versus Splanchnic Nerve Neurolysis
Pain is prevalent among patients with gastrointestinal cancers. Standard procedures such as coeliac plexus neurolysis (CPN) is effective in reducing pain, opioid requirement and related side effects for pancreatic cancer cases.
- Trial name
- NCT05541211
- Testing
- Coeliac plexus neurolysis, Splanchnic nerve neurolysis
- Where
- Hong Kong
- Volunteers
- 100 people
- Sponsor
- The University of Hong Kong
Upper Abdominal Malignancies
Coeliac Plexus vs Splanchnic Nerve Neurolysis for Upper Abdominal Cancer Pain
The goal of this clinical trial is to determine whether Neurolytic Splanchnic Nerve Block (NSNB) reduces pain in adults with upper abdominal malignancies.
- Trial name
- NCT07653906
- Testing
- Neurolytic Coeliac Plexus Block (NCPB), Neurolytic Splanchnic Nerve Block (NSNB)
- Where
- Bangladesh
- Volunteers
- 44 people
- Sponsor
- Bangladesh Medical University
Knee Osteoarthritis
Knee Genicular Nerve Ablation by Thermal Radiofrequency vs Thermal Radiofrequency Plus Alcohol Neurolysis
the aim of our study is to compare effectiveness (satisfaction) and duration of pain relief between patients receiving the conventional thermal radiofrequency on the genicular nerves alone vs patients who will receive the…
- Trial name
- NCT05980338
- Testing
- genicular nerve ablation by thermal radiofrequency, genicular nerve ablation by thermal radiofrequency plus alcohol neurolysis
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Ain Shams University
Pancreatic Cancer
Trial Comparing Two Techniques of Celiac Plexus Neurolysis for Treatment of Pain in Carcinoma Pancreas
Coeliac plexus neurolysis (CPN) is a management option for pain control in carcinoma pancreas.CPN is conventionally performed by percutaneous technique with fluoroscopic guidance.
- Trial name
- NCT01182831
- Testing
- percutaneous fluoro guided celiac plexus neurolysis, EUS guided neurolysis
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Asian Institute of Gastroenterology, India
Osteoarthritis, Knee, Knee Pain Chronic
Phenol Neurolysis of Genicular Nerves for Osteoarthritic Knee Pain
As the aging and obese populations continue to increase, there is a rapidly growing number of people at risk for knee osteoarthritis. Treatment typically starts conservatively with analgesics, physical therapy, and bracing.
- Trial name
- NCT04989660
- Testing
- 6% aqueous phenol, Isotonic saline
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Pudendopathie, Clunealgie
New Endoscopic Minimal Invasive Approach for Pudendal Nerve and Inferior Cluneal Nerve Neurolysis: a Clinical Study
Pudendal nerve and cluneal nerve entrapment can cause a neuropathic pain syndrome in one, many or all of the sensitive areas innervated by this nerve.
- Trial name
- NCT03883178
- Testing
- Minimal-invasive endoscopic transgluteal approach
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Katleen JOTTARD
Low Back Pain
Effectiveness of Percutaneous Lumbar Epidural Adhesiolysis and Neurolysis on Low Back Pain
Clinically significant improvements in the percutaneous adhesiolysis patients with hypertonic neurolysis compared to those patients randomized to the control group who did not receive adhesiolysis and hypertonic saline…
- Trial name
- NCT00370994
- Testing
- Caudal epidural injection, Percutaneous adhesiolysis
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Pain Management Center of Paducah