Clinical trials: Nail Diseases
Diabetes Mellitus, Healthy
Reconfirming the Safety and Performance of the Glyconics-DS System in Known Populations With and Without Diabetes
A single-site, open label, confirmatory study assessing two biomarkers indicative of levels of glycaemia; glycated keratin in fingernails and glycated haemoglobin (HbA1c). Screening for diabetes
- Trial name
- ANODE04 (NCT07039357)
- Testing
- Near-infrared (spectroscopy) for non-invasive assessment of glycated keratin of nail
- Where
- 2 sites in United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Glyconics Ltd
Onychomycosis
Evaluation of the Suitability of PD P 506 A in the PDT of Distal Subungual Onychomycosis (DSO) of the Great Toenail.
This study evaluates the potential usefulness of photodynamic therapy with PD P 506 A in patients with distal subungual onychomycosis of the great toenail.
- Trial name
- NCT02355899
- Testing
- PD P 506 A
- Where
- 2 sites in Germany
- Volunteers
- 25 people
- Sponsor
- photonamic GmbH & Co. KG
Trochanteric Fracture of Femur, Osteoporotic Fracture of Femur
FARE Augmentation of Proximal Femoral Fractures With CaS/HA and Systemic ZA
The goal of this clinical trial is to investigate the new bone formation around a metal device in the femoral head in patients with osteoporotic hip fractures undergoing surgical treatment with nails.
- Conditions
- Trochanteric Fracture of Femur, Osteoporotic Fracture of Femur, Hip Fractures, Bone Density, Low
- Trial name
- NCT06135298
- Testing
- OSTEOSYNTHESIS, Zoledronic acid, CERAMENT BONE VOID FILLER (BVF)
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Aksaray University
Fractures, Bone, Impending Fracture
Retrospective Study on Clinical Performance and Safety Profile of Agile Nail
This study aims to retrospectively collect data from routine clinical practice in order to evaluate the safety profile of the Agile intramedullary nail, used in pediatric patients according to the manufacturer Instructions For…
- Conditions
- Fractures, Bone, Impending Fracture, Deformity; Bone
- Trial name
- Agile (NCT06412939)
- Testing
- Agile Nail
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Orthofix s.r.l.
Foot Dermatoses
Antifungal Activity of Loceryl Nail Lacquer in Combination With a Cosmetic Varnish
The main objective is to compare efficacy, in terms of antifungal activity of Loceryl Nail Lacquer associated with a Cosmetic Varnish and Loceryl Nail Lacquer alone, in the treatment of mild to moderate toenail Distal Subungual…
- Trial name
- COOL (NCT02321098)
- Testing
- Loceryl NL + Cosmetic varnish, Loceryl NL 12 weeks, Loceryl NL 15 months
- Where
- Iceland
- Volunteers
- 50 people
- Sponsor
- Galderma R&D
Nails, Ingrown, Coagulation Defect; Bleeding
Hemostasis Assesment After Application of Lyophilisate Collagen in Nail Surgery
The objective of this study is to evaluate the hemostatic capacity of two types of collagen hemostatic sponges in nail surgery. It is a randomized triple-blind clinical trial with two experimental groups (medium porosity collagen…
- Trial name
- NCT05140161
- Testing
- collagen
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- University of Seville
Leg Length Inequality
SYNOSTE Nitinail System Trial
SYNOSTE Nitinail System Trial is an international multicenter open label single-arm equivalence study to verify whether the leg-lengthening procedure can be adequately controlled with the SNS system as measured with the…
- Trial name
- NCT03752814
- Testing
- SYNOSTE Nitinail System
- Where
- 2 sites in Finland, Turkey (Türkiye)
- Volunteers
- 9 people
- Sponsor
- SYNOSTE Oy
Onychomycosis
Absorption and Systemic Study of AN2690 in Patients With Moderate to Severe Onychomycosis (ADME II)
The purpose of the study is to determine the absorption and systemic pharmacokinetics of AN2690 following daily application to all ten (10) toenails for 28 days.
- Trial name
- NCT00679601
- Testing
- AN2690
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Pfizer
Onychomycosis
Clinical Trial on Onychomycosis With P-3058 Nail Solution in Pediatric Population
Pediatric patients affected by mild-to-moderate distal subungual onychomycosis (DSO) or affected by white superficial onychomycosis (WSO), due to dermatophytes, will be treated topically with P-3058 nail solution according to the…
- Trial name
- NCT02547701
- Testing
- P-3058
- Where
- 5 sites in Belgium, Germany and 3 more
- Volunteers
- 20 people
- Sponsor
- Polichem S.A.
Onychomycosis
TDT 067 Open Label Multi-Dose Onychomycosis Study
The aim of this study is to establish a clinical bridge to Lamisil® tablets by conducting a clinical pharmacokinetic (PK) study comparing the systemic exposure of a Lamisil® tablet with that of with TDT 067 under maximal use…
- Trial name
- NCT01790165
- Testing
- TDT067 and Lamisil
- Volunteers
- 27 people
- Sponsor
- Celtic Pharma Development Services
Onychomycosis of Toenail
An Internet Mediated Research Study to Assess the Quality of Life of Consumers With Self-reported Fungal Nail Infection (Onychomycosis) During Treatment With Scholl Fungal Nail.
To evaluate the effect on quality of life of consumers with self-reported onychomycosis during the first 4 weeks of treatment in relation to the appearance of the infected toenail.
- Trial name
- NCT04084782
- Testing
- Fungal Nail Treatment Kit
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- Reckitt Benckiser Healthcare (UK) Limited
Psoriatic Arthritis
Distal Erosions and Nail Psoriasis
Nearly 30% of patients with cutaneous psoriasis (PsO) developed psoriatic arthritis (PsA). Among these patients 20 % will have severe destructive arthritis.
- Trial name
- PSUPSO (NCT02813720)
- Testing
- HR-pQCT High resolution peripheral quantitative CT-scan
- Where
- France
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Mild to Moderate Acne, Stiffness of Joint, Nec, Involving Ankle and Foot in MDR24_1
A Proof of Science, Dose-Response Study to Evaluate the Safety, Efficacy of Different Dosages of Test Treatments
A proof of science clinical study with randomized, four-arm, comparative, single-blind, within the arm - Dose-Response Study to evaluate the safety and efficacy of different collagen peptide-containing test treatments in adult…
- Conditions
- Mild to Moderate Acne, Stiffness of Joint, Nec, Involving Ankle and Foot in MDR24_1, Other Specified Diseases of Hair and Hair Follicles, Brittle Nails
- Trial name
- NCT05613660
- Testing
- Veg Collagen Peptide, Bovine Collagen Peptide, Fish | Marine Collagen Peptide
- Where
- India
- Volunteers
- 264 people
- Sponsor
- NovoBliss Research Pvt Ltd
Onychomycosis
Single-blind Evaluation of Device to Nail Micro-drilling in Onychomycosis
Based on manufacturer testing, no major difference in drilling condition is expected in this study compared to the drilling conditions previously established.
- Trial name
- NCT00941317
- Testing
- Pathformer (micro-drilling device)
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Galderma R&D
Osteogenesis
Telescoping Nail in Osteogenesis Imperfecta
Osteogenesis Imperfecta (OI) is an autosomal dominant disorder that mainly affects the bones. Bones break easily. The severity may be mild to severe.
- Trial name
- Telescoping (NCT06591546)
- Testing
- Telescoping nail
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Al-Azhar University
Chemotherapeutic Agent Toxicity, Pain
Cryotherapy in Preventing Peripheral Neuropathy and Nail Toxicity in Patients With Breast Cancer Who Are Receiving Paclitaxel
RATIONALE: Cryotherapy may help prevent peripheral neuropathy or nail toxicity in patients receiving chemotherapy. PURPOSE: This clinical trial studies cryotherapy in preventing peripheral neuropathy and nail toxicity in patients…
- Conditions
- Chemotherapeutic Agent Toxicity, Pain, Peripheral Neuropathy, Recurrent Breast Cancer
- Trial name
- NCT01243541
- Testing
- cryotherapy, questionnaire administration, quality-of-life assessment
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Northwestern University
Onychomycosis
Systemic Antifungal Plus Q-Switched Nd:YAG Laser for Onychomycosis
This randomized controlled trial aims to compare the efficacy and safety of systemic terbinafine combined with Q-switched Nd:YAG laser versus systemic terbinafine alone in the treatment of onychomycosis.
- Trial name
- NCT07869706
- Testing
- Terbinafine, Q-switched Nd:YAG laser
- Volunteers
- 97 people
- Sponsor
- Assiut University
Onychomycosis
Study Efficacy and Safety in Comparative Use of Investigational Product Adjuvant Treatment in Onychomycosis
Single-center study, single blind, comparative with the objective of evaluating the efficacy and safety of an investigational product as an adjunct in the treatment of onychomycosis improvement of 90 days ± 2 days.
- Trial name
- NCT02961634
- Testing
- Nailner 2 in 1, Ciclopirox 8%
- Volunteers
- 46 people
- Sponsor
- MIP Brasil Indústria e Comércio de Produtos Farmacêuticos LTDA
Onychomycosis
Evaluating the Safety, Tolerability and Preliminary Efficacy of Plasma in Improving the Appearance of Onychomycosis
The purpose of this study is to evaluate the safety and preliminary efficacy of using electrical plasma to treat toenail fungus.
- Trial name
- NCT02724384
- Testing
- MOE Plasma Delivery System A, MOE Plasma Delivery System B
- Where
- 7 sites in United States
- Volunteers
- 75 people
- Sponsor
- Moe Medical Devices
Fusariosis, Onychomycosis
Anti-mold Azole in the Prophylaxis for Invasive Fusariosis
Patients admitted for autologous or allogeneic hematopoietic cell transplantation, induction-remission chemotherapy for acute myeloid leukemia, myelodysplasia or acute lymphoid leukemia, or to receive immunosuppressive therapy…
- Trial name
- Fusarproph (NCT02714504)
- Testing
- Voriconazole or posaconazole
- Where
- Brazil
- Volunteers
- 239 people
- Sponsor
- Universidade Federal do Rio de Janeiro