Clinical trials: Nasal Airway Obstruction
Obstructive Sleep Apnea, Hypertonia, Muscle
Self-Supporting Nasopharyngeal Airway (ssNPA) Treating Upper Airway Obstruction in Hypotonia
The researchers are investigating if the Self-Supporting Nasopharyngeal Airway (ssNPA) device can be used in the treatment of obstructive sleep apnea in children with Hypotonic Upper Airway Obstruction (HUAO).
- Conditions
- Obstructive Sleep Apnea, Hypertonia, Muscle, Nasal Airway Obstruction, Tolerance
- Trial name
- NCT05527652
- Testing
- Self-Supporting Nasopharyngeal Airway (ssNPA)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Michigan
Nasal Airway Obstruction
Measuring Nasal Airway Changes After VivAer Treatment Using AI Analysis
The goal of this clinical trial is to measure changes in the nasal airway after treatment with the VivAer® procedure in adults aged 22 to 85 with nasal airway obstruction caused by nasal valve dysfunction.
- Trial name
- BREATHE AI (NCT07574918)
- Testing
- VivAer Stylus
- Volunteers
- 30 people
- Sponsor
- Aerin Medical
Nasal Septal Deviation, Nasal Airway Obstruction
Open-Label Study to Evaluate the Safety and Effectiveness of the Spirair Implant
Pilot study of bioabsorbable implant and delivery device for correction of septal deviation.
- Trial name
- NCT06163404
- Testing
- Implantation of Spirair Nasal Device using the Spirair delivery system.
- Where
- 8 sites in United States
- Volunteers
- 102 people
- Sponsor
- Spirair, Inc
Nasal Airway Obstruction
A Prospective Study Comparing VivAer to Alternative Surgical Procedures to Treat Nasal Airway Obstruction in Patients With Nasal Valve Dysfunction.
The purpose of this study is to compare the clinical outcomes of the VivAer procedure to functional rhinoplasty and septoplasty surgery for the treatment of nasal airway obstruction (NAO) to establish non-inferiority.
- Trial name
- CompAer (NCT06922955)
- Where
- 35 sites in United States
- Volunteers
- 400 people
- Sponsor
- Aerin Medical
Apnea, Airway Obstruction, Nasal
Upper Airway's Pressure Drop Analyses After Mandibular Advancement and Maxillary Expansion
Breathing is a crucial function for everyone. Breathing impairment in children could lead to behavioral and cognitive problems at least.
- Conditions
- Apnea, Airway Obstruction, Nasal, Mandible Small, Maxillary Hypoplasia
- Trial name
- NCT04190953
- Testing
- Twin block then Hyrax, Hyrax then Twin block
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Nasal Airway Obstruction
An Ambispective Registry Study Comparing Clinical Outcomes of Surgical Interventions for the Treatment of Nasal Airway Obstruction.
The purpose of this study is to assess and compare the clinical outcomes associated with common surgical interventions for the treatment of nasal airway obstruction (NAO).
- Trial name
- DUO (NCT06992037)
- Where
- United States
- Volunteers
- 1,110 people
- Sponsor
- Aerin Medical
Hypotonia, Muscle, Obstructive Sleep Apnea
Long-term Evaluation of Nasopharyngeal Airway in Hypotonia
This research is studying the long term use of a nasal airway device (self-supporting nasopharyngeal airway; "ssNPA") in children with hypotonic upper airway obstruction to learn about its effectiveness and tolerability as a…
- Conditions
- Hypotonia, Muscle, Obstructive Sleep Apnea, Nasal Airway Obstruction
- Trial name
- NCT06614582
- Testing
- Self-Supporting Nasopharyngeal Airway (ssNPA)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Michigan
Nasal Airway Obstruction
Vivaer® Procedure for Treatment of Nasal Airway Obstruction Study
The purpose of this study is to compare the Vivaer procedure with radiofrequency (RF) energy to sham procedure for treatment of nasal airway obstruction (NAO).
- Trial name
- VATRAC (NCT04549545)
- Testing
- Vivaer ARC Stylus
- Where
- 12 sites in United States
- Volunteers
- 119 people
- Sponsor
- Aerin Medical
Maxillary Retrusion, Nasal Airway Obstruction
Evaluation of the Effect of Three Types of Rapid Maxillary Expanders (Conventional, Hybrid and MSE)
Aim of the study: To compare radiographically the morphometric changes in the nasal airway after using three types of rapid maxillary expansion (RME) conventional hyrax (CH), hybrid hyrax (HH) and maxillary skeletal expander…
- Trial name
- NCT05446714
- Testing
- CH 4 band, HH 2 bands, MSE 2 bands and 4
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- Al-Azhar University
Nasal Airway Obstruction
Novapak Prospective Observational Clinical Trial
The Novapak study is a prospective, observational, multi-site, non-controlled, non-randomized, case-series, with a 2 week and 1-month follow-up in adults undergoing nasal/sinus surgery with Novapak Nasal Sinus Packing and Stent…
- Trial name
- Novapak (NCT05747014)
- Testing
- Novapak Nasal Sinus Packing and Stent
- Where
- 4 sites in United States, Canada
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Medtronic Surgical Technologies
Supraglottic Airway Obstruction, Airway Complication of Anesthesia
Wei Nasal Jet Tube vs Nasal Cannula Oxygen Support in Gastrointestinal Endoscopy Patients
Sedoanalgesia is applied to patients during gastrointestinal endoscopy. Sedoanalgesia may cause respiratory depression and hypoxia in patients.
- Conditions
- Supraglottic Airway Obstruction, Airway Complication of Anesthesia, Airway Obstruction, Anesthesia Complication
- Trial name
- NCT05783050
- Testing
- Wei Nasal Jet Tube, Nasal Cannula Oxygen Support
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Nasal Obstruction, Medically Unexplained Symptoms
VivAer: A Correlation Between Symptom Scores and Objective Findings
This is a prospective, single-center study. This study seeks to determine the objective improvement in nasal airflow in patients after undergoing the VivAer procedure, which involves the use of a stylus to deliver controlled and…
- Conditions
- Nasal Obstruction, Medically Unexplained Symptoms, Airway Obstruction, Airway Remodeling
- Trial name
- NCT05573919
- Testing
- VivAer Stylus
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- Endeavor Health
Sedation Complication, Obesity
Effect of HFNO on Spontaneous Ventilation in Obese Patients During Analgo-sedation for Vitrectomy
Patients suffering from pathology of posterior eye chamber such as diabetic retinopathy, retinal detachment, traumatic eye injury, retained lens fragments, macular hole, pucker, dislocated intraocular lens after cataract surgery…
- Conditions
- Sedation Complication, Obesity, Hypoxic Respiratory Failure, Airway Obstruction, Nasal
- Trial name
- NCT04049240
- Testing
- Device: low-flow nasal oxygenation (LFNO) 18<BMI<30 kg/m2, Device: low-flow nasal oxygenation (LFNO) 30≤BMI<35 kg/m2, Device: low-flow nasal oxygenation (LFNO) BMI≥35 kg/m2
- Where
- Croatia
- Volunteers
- 126 people
- Sponsor
- University of Split, School of Medicine
Nasal Airway Obstruction
Thermal Imaging as a Potential Diagnostic Tool of Nasal Airflow
Currently, there are no tools that can measure nasal airflow in an objective manner that is non-invasive to the patient. This clinical study aims to address this by evaluating the use of thermal imaging as a diagnostic tool for…
- Trial name
- NCT03233373
- Testing
- Seek CompactPro thermal imager
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- New York City Health and Hospitals Corporation
Nasal Airway Obstruction
InFlux System for Nasal Breathing Improvement
Pilot Study of the Aerin Medical Wand used for Improvement in Nasal Breathing
- Trial name
- NCT01960816
- Testing
- Procedure: thermal coagulation of tissue in the nasal airway
- Where
- 2 sites in United States
- Volunteers
- 33 people
- Sponsor
- Aerin Medical