Clinical trials: Nasal Allergies
Perennial Allergic Rhinitis
Cosalin® Monotherapy Versus Cosalin® and Xarlin® Combination Therapy
Title of Study: A randomized, parallel, double-blind, multi-center, comparative study to evaluate the efficacy and safety of Cosalin monotherapy versus Cosalin and Xarlin combination therapy in patients with allergic rhinitis…
- Trial name
- NCT01062139
- Testing
- Xarlin (Levocetirizine), Cosalin (Petasites hybridus CO2 extract)
- Volunteers
- 100 people
- Sponsor
- HK inno.N Corporation
Rhinitis, Allergic, Perennial
Clinical Study, Non Inferiority Between Noex® 32µg Versus Budecort Aqua® 32µg in Treatment of Alergic Rhinitis
This study is to evaluate non inferiority of Eurofarma budesonide nasal spary x referral Astrazeneca budesonide. Half patients will receive Eurofarma medication and half patients will receive Astrazeneca medication.
- Trial name
- RINEX32 (NCT02972866)
- Testing
- Budesonide
- Where
- Brazil
- Sponsor
- Eurofarma Laboratorios S.A.
Rhinitis, Allergic, Seasonal
Fluticasone Furoate Nasal Spray Versus Oral Fexofenadine
The primary objective of this study is to compare the nighttime symptom relief of fluticasone furoate nasal spray and oral fexofenadine
- Trial name
- NCT00435461
- Testing
- Fluticasone furoate and fexofenadine
- Where
- 6 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- GlaxoSmithKline
Rhinitis, Conjunctivitis
Study on Pharmacodynamic Parameter and Tolerability With Subcutaneous Immunotherapy in Grass Pollen Allergic Patients
The aim of this study is to test the pharmacodynamic equivalence with respect to IgE-blocking factor and to compare the tolerability of two different updosing schedules with ALK-Flex SQ
- Conditions
- Rhinitis, Conjunctivitis, Asthma
- Trial name
- NCT00857779
- Testing
- subcutaneous immunotherapy
- Where
- Germany
- Volunteers
- 473 people
- Sponsor
- ALK-Abelló A/S
Seasonal Allergy
Efficacy of 2LALERG (Homeopathic Drug) in Allergic Rhinitis Related to Grass Pollen
The primary objective of this study is to demonstrate the superiority of 2L®ALERG over placebo in terms of efficacy on the symptoms of allergic rhinitis and allergic rhinoconjunctivitis in patients with seasonal allergy to grass…
- Trial name
- LLB-2016-01 (NCT02690935)
- Testing
- 2LALERG
- Where
- Belgium
- Volunteers
- 102 people
- Sponsor
- Labo'Life
Rhinitis, Allergic, Perennial and Seasonal
A Comparator Study of Fluticasone Propionate Nasal Spray Verses (vs) Cetirizine in the Treatment of Seasonal Allergic Rhinitis
This phase IV investigational trial is being conducted to evaluate the efficacy of a 2-week treatment of fluticasone propionate nasal spray (FPNS) vs.
- Trial name
- NCT01916226
- Testing
- FPNS, Cetirizine
- Where
- 31 sites in United States
- Volunteers
- 682 people
- Sponsor
- GlaxoSmithKline
Allergic Rhinitis
Study of an Investigational Nasal Aerosol or Placebo in Children (Ages 4 to 11) With Perennial Allergic Rhinitis (PAR)
The purpose of this study is to evaluate the efficacy and safety of Beclomethasone dipropionate (BDP) nasal aerosol in subjects with Perennial Allergic Rhinitis (PAR).
- Trial name
- NCT01783548
- Testing
- BDP Nasal Aerosol
- Where
- 63 sites in United States
- Volunteers
- 547 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Anaphylaxis, Anaphylactic Reaction
Comparative Bioavailability of Intranasal Epinephrine
A Study to Compare the Bioavailability of Epinephrine following a Single Nasal Dose of FMXIN002 Microspheres Powder 3.6 mg, and 4mg with EpiPen 0.3mg Intramuscular Injection in Healthy Adults
- Trial name
- NCT06205134
- Testing
- A: Epinephrine injection, B: FMXIN002 3.6mg, C: FMXIN002 4.0mg
- Where
- Israel
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Nasus Pharma
Seasonal Allergic Rhinitis
Single-Center, Double-Blind, Randomized , Parallel Study Comparing Onset of Action, Efficacy & Safety of a Single-Dose of Fexofenadine HCl 180 mg vs Montelukast Na 10 mg & Placebo in Treating Seasonal Allergic Rhinitis Subjects in an Allergen Exposure Unit
The primary objective of this study is to determine the efficacy and onsets of action of single-dose fexofenadine hydrochloride 180 mg and montelukast sodium 10 mg relative to placebo.
- Trial name
- NCT00637611
- Testing
- Fexofenadine HCl
- Where
- United States
- Volunteers
- 1,010 people
- Sponsor
- Sanofi
Perennial Allergic Rhinitis (PAR)
A Study of Lebrikizumab in Adult Participants With Perennial Allergic Rhinitis (PREPARED-1)
The main purpose of this study is to evaluate the efficacy and safety of lebrikizumab in adult participants with perennial allergic rhinitis. Participants can expect study participation to last up to 29.5 months.
- Trial name
- NCT06339008
- Testing
- LY3650150, Standard therapy for INCS
- Where
- 74 sites in United States, Belgium and 4 more
- Volunteers
- 450 people
- Sponsor
- Eli Lilly and Company
Seasonal Allergies
MK0524 Seasonal Allergic Rhinitis Study (0524-005)(COMPLETED)
To assess the efficacy of MK0524 on seasonal allergies.
- Trial name
- NCT00533208
- Testing
- MK0524
- Volunteers
- 766 people
- Sponsor
- Merck Sharp & Dohme LLC
Perennial Allergic Rhinitis (PAR)
Effectiveness of Beclomethasone Dipropionate Nasal Aerosol for Perennial Allergic Rhinitis
This study will be a prospective observational study of "real world" BDP nasal aerosol users with PAR, with or without seasonal allergic rhinitis (SAR).
- Trial name
- BALANCE (NCT01632540)
- Testing
- Beclomethasone Dipropionate (BDP) Nasal Aerosol
- Where
- 46 sites in United States
- Volunteers
- 824 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Rhinitis Allergic
Evaluation of Efficacy of Dellegra in Exposure Unit
Primary Objective: To collect and analyze clinical data of Allergic Rhinitis patients' Total Nasal Symptom Score (TNSS) change after Dellegra internal use under high density pure Japanese cedar pollen exposure.
- Trial name
- NCT02175485
- Testing
- Fexofenadine HCl 30 mg+Pseudophedrine HCl 60 mg
- Where
- Japan
- Volunteers
- 24 people
- Sponsor
- Sanofi
Grass Pollen Induced Allergic Rhinoconjunctivitis
Evaluation of the Efficacy and Safety of AVANZ® Phleum Pratense in Grass Pollen-induced Allergic Rhinitis During Controlled Exposure in an Environmental Challenge Chamber
The clinical trial will investigate the efficacy of Avanz Phleum pratense in the treatment of rhinitis in an environmental challenge chamber.
- Trial name
- AV-G-03 (NCT02166268)
- Testing
- AVANZ Phleum pratense 15,000 SQ+
- Where
- Germany
- Volunteers
- 140 people
- Sponsor
- ALK-Abelló A/S
Rhinitis, Allergic
MK0476 Study in Adult Patients With Perennial Allergic Rhinitis (0476-397)(COMPLETED)
A clinical study evaluates the efficacy and safety of MK0476 in adult patients with Perennial Allergic rhinitis.
- Trial name
- NCT00771160
- Testing
- montelukast sodium
- Volunteers
- 120 people
- Sponsor
- Organon and Co