Clinical trials: Nasal Bleeding
Hereditary Haemorrhagic Telangiectasia
Iron Deficiency and Hereditary Haemorrhagic Telangiectasia
Managing iron deficiency is important for more than 1 billion individuals worldwide, to avoid blood transfusions, or excessive strain on vital organs that depend on iron-containing haemoglobin to deliver oxygen to the tissues.
- Trial name
- NCT01908543
- Testing
- Ferrous sulphate 200mg oral tablet
- Where
- United Kingdom
- Volunteers
- 3 people
- Sponsor
- Imperial College London
Epistaxis
Hot Water Irrigation in Posterior Epistaxis
This study was aimed to assess the efficacy and factors affecting the success of hot water irrigation in management of posterior epistaxis.
- Trial name
- NCT04151888
- Testing
- Foley catheter
- Volunteers
- 20 people
- Sponsor
- Assiut University
Lacrimal Duct Obstruction
Risk and Importance of Peroperative Nasal Hemorrhage in the Treatment of Lacrimal Duct Obstruction in Young Children
The aim of the study is to evaluate the risk in intra-operative nasal hemorrhage when using a "pushed" probe (Master Ka) in the treatment of naso lacrimal duct obstruction (NLDO).
- Trial name
- CANALHEMO (NCT02851641)
- Testing
- "pushed" mono-canaliculonasal intubation
- Where
- France
- Volunteers
- 108 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Nasal Polyps
The Effect of Preoperative Oral Prednisone on the Operative Field During Nasal Polypectomy.
This study aims to determine if a short course of oral prednisone helps to improve the operative field and ease of surgery by minimizing bleeding during nasal polypectomy surgery.
- Trial name
- NCT00440219
- Testing
- Oral Prednisone
- Where
- 2 sites in Canada
- Volunteers
- 34 people
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Intubation Complication
Nasal Intubation：a Comparison of Different Endotracheal Tubes
Either uses two different endotracheal tubes to pass the nasal cavity and to compare the effects on the secretion and bleeding volume of patients during intubation to facilitate nasotracheal tube advancement.
- Trial name
- NCT05112783
- Testing
- Henan Tuoren Endotracheal Tube, Smiths Portex Tracheal Tubes
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Atmospheric Pressure; Adverse Effect, Epistaxis Nosebleed
Atmospheric Pressure and Epistaxis Relationship
In this study, investigators aim to understand the relationship between changes in atmospheric pressure and blood pressure, and to investigate whether these changes have an impact on the etiology of epistaxis.
- Trial name
- NCT06531577
- Where
- Turkey (Türkiye)
- Volunteers
- 600 people
- Sponsor
- Saglik Bilimleri Universitesi
Chronic Rhinosinusitis (Diagnosis)
Adrenaline Solution Irrigation and Bleeding During Sinus Surgery
Intranasal irrigation with normal saline is routinely used in sinus surgery to clean the tip of the nasal endoscope and clear the surgical field from blood.
- Trial name
- NCT04551703
- Testing
- Adrenaline saline irrigation
- Volunteers
- 60 people
- Sponsor
- Jordan University of Science and Technology
Epistaxis
Epistaxis in Patients Receiving Oral Anticoagulants and Antiplatelet: Prevalence Risk Factors at a Tertiary Care Hospital in Nepal
This study aims to determine the prevalence of epistaxis and identify the associated risk factors among patients receiving oral anticoagulants and antiplatelet at a tertiary care hospital in Nepal.
- Trial name
- Epistaxis (NCT06906861)
- Where
- Nepal
- Volunteers
- 284 people
- Sponsor
- Institute of medicine, Maharagjung medical campus
Anterior Epistaxis
Topical 15% Trichloroacetic Acid Versus Silver Nitrate Cauterization in the Management of Idiopathic Childhood Epistaxis: A Prospective Double-Blinded, Randomized Clinical Trial
the invistigators aim to explore the efficacy of trichloroacetic acid as a chemical cauterization agent and compare it with that of silver nitrate in the treatment of idiopathic epistaxis in children.
- Trial name
- Epistaxis (NCT06836791)
- Testing
- chemical cautrizating agents to stop epistaxis, Silver Nitrate, Trichloroacetic Acid Topical
- Where
- Egypt
- Volunteers
- 170 people
- Sponsor
- Youssef Zaki
Sinus Disease, Anesthesia
Bupivacaine and Epinephrine Injection Study
Endoscopic sinus surgery (ESS) is a common otolaryngologic procedure that aims to remove the partitions that separate the sinus cavities, remove inflamed tissue, and optimize the sinuses for topical medication use.
- Conditions
- Sinus Disease, Anesthesia, Bleeding
- Trial name
- NCT06456255
- Testing
- Sensorcaine with Epinephrine
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Amin Javer
Telangiectasia, Hereditary Hemorrhagic, Rendu Osler Disease
Efficacy of Nintedanib Per os as a Treatment for Epistaxis in HHT Disease.
The recognized manifestations of HHT are all due to abnormalities in vascular structure. Epistaxis are spontaneous, very variable, may occur as often as several times every day, and are recurrent in 90% of patients and associated…
- Trial name
- EPICURE (NCT03954782)
- Testing
- Nintedanib 150 mg and 100 mg soft capsules
- Where
- 8 sites in France
- Volunteers
- 61 people
- Sponsor
- Hospices Civils de Lyon
Epistaxis
Minimally Invasive Control of Epistaxis (MICE)
Epistaxis is a common disorder with 60% of the population suffering from one episode and 10% of these cases requiring medical attention.
- Trial name
- MICE (NCT00666471)
- Testing
- MICE, SPA ligation
- Where
- Canada
- Volunteers
- 3 people
- Sponsor
- University of Calgary
Postoperative Pain
RADA16 for Adult Tonsillectomy
The purpose of the research is to determine if RADA16 (also known as PuraStat®, PuraGel®, or PuraSinus®) improves patient outcomes following tonsillectomy procedures.
- Trial name
- NCT07060495
- Testing
- RADA16 hydrogel
- Where
- 2 sites in United States
- Volunteers
- 134 people
- Sponsor
- Rutgers, The State University of New Jersey
Nasal Bleeding
Epinephrine Nebulization Prior to Nasotracheal Intubation
This randomised, prospective study performed in Ain shams university hospitals over 126 Patients ASA I and ASA II, trauma patients who suffered isolated mandibular fractures and necessitated nasal intubation during general…
- Trial name
- NCT05738564
- Testing
- Epinephrine Inhalation Solution
- Where
- Egypt
- Volunteers
- 126 people
- Sponsor
- Ain Shams University
Nasal Polyps
Comparison of Intraoperative Outcomes of Microdebrider-Assisted Versus Conventional Functional Endoscopic Sinus Surgery in Patients With Sinonasal Polyposis
This study compared two surgical techniques for patients with nasal polyps affecting both sides of the nose and sinuses. Nasal polyps were soft swellings that caused symptoms such as nasal blockage, nasal discharge, and reduced…
- Trial name
- NCT07907393
- Testing
- Microdebrider-Assisted Functional Endoscopic Sinus Surgery, Conventional Functional Endoscopic Sinus Surgery
- Where
- Pakistan
- Volunteers
- 56 people
- Sponsor
- Lahore General Hospital
Epistaxis Nosebleed
Nasal Compression Device Study for Epistaxis
This study will explore how a nasal compression device compares to manual compression for stopping anterior nosebleeds. This will be a non-randomized controlled trial enrolling participants presenting to medical care for anterior…
- Trial name
- NCT05789264
- Testing
- Nasal Compression Device, Routine Care
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- NasaClip
Postoperative Bleeding, Skin Cancer Face
Tranexamic Acid in Nasal Mohs Reconstruction
This study will be a prospective randomized control trial to evaluate the effects of subcutaneously administered TXA among patients undergoing nasal Mohs reconstruction with local flaps at VUMC.
- Trial name
- NCT06057675
- Testing
- Treatment (tranexamic acid and 1% lidocaine with 1:100,000 epinephrine), Control (1% lidocaine with 1:100,000 epinephrine)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Nosebleed (Epistaxis) - Posterior or Anterior
Long Term Results and Complications After Epistaxis Treatment
The aim of this study is to find the most agreeable and in the long term most efficient treatment for epistaxis.
- Trial name
- NCT02127554
- Where
- Switzerland
- Volunteers
- 591 people
- Sponsor
- University of Zurich
Pain, Postoperative Pain
A Comparison Between Conventional Throat Packs and Pharyngeal Placement of Tampons in Rhinology Surgeries
Post-operative, throat pain, nausea and vomiting is a common occurrence in rhinology surgeries due to the use of throat packs during the procedure.
- Conditions
- Pain, Postoperative Pain, Bleeding, Nose Bleed
- Trial name
- NCT03678168
- Testing
- Throat Pack, Pharyngeal Tampons
- Where
- Bahrain
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- King Hamad University Hospital, Bahrain
Telangiectasia, Hereditary Hemorrhagic, Osler Rendu Disease
Efficacy of a Timolol Nasal Spray as a Treatment for Epistaxis in Hereditary Hemorrhagic Telangiectasia (HHT) - (TEMPO)
Timolol is a nonselective β-blocker commonly used in the treatment of glaucoma. Recently it has been used topically for the treatment of superficial hemangiomas.
- Trial name
- TEMPO (NCT02484716)
- Testing
- Timolol nasal spray
- Where
- France
- Volunteers
- 58 people
- Sponsor
- Hospices Civils de Lyon