Clinical trials: Nasal Cannula
Hypercapnia, Sedation Complication
Ventilatory Effects of THRIVE During EBUS
High flow nasal cannula (HFNC) is used in interventional procedures to prevent hypoxia during sedation. In patients with a patent airway, HFNC reduces dead space ventilation as well.
- Conditions
- Hypercapnia, Sedation Complication, High Flow Nasal Cannula
- Trial name
- NCT05505279
- Testing
- THRIVE (High Flow Nasal Cannula)
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Rijnstate Hospital
Pneumonia-associated Acute Hypoxemic Respiratory Failure
Non-invasive Ventilation Versus High Flow Oxygen
The purpose of the study is to compare the efficacy of alternating Non Invasive Ventilation NIV and High Flow Oxygen HFO compared to High Flow Oxygen HFO alone on gas exchanges and prognosis in pneumonia-associated acute…
- Trial name
- HFO (NCT03758508)
- Testing
- High Flow Oxygen nasal cannula, Noninvasive ventilation
- Where
- Italy
- Volunteers
- 128 people
- Sponsor
- Niguarda Hospital
Intubation, Cardiovascular Surgical Procedure
Reducing Reintubation Risk in High-Risk Cardiac Surgery Patients With High-Flow Nasal Cannula
The iCAN trial is a pragmatic randomized controlled trial that aims to test the hypothesis that HFNC versus usual care oxygenation strategies applied immediately after initial extubation after cardiac surgery decreases the…
- Trial name
- NCT04782817
- Testing
- Recommendation for high flow nasal cannula oxygen therapy order set, Provider choice usual care order set
- Where
- United States
- Volunteers
- 3,568 people
- Sponsor
- Vanderbilt University Medical Center
High-flow Nasal Cannula Oxygen
Evaluating High-flow Nasal Cannula Oxygen Therapy Through LUS During Weaning
Respiratory distress after extubation is associated with increased morbidity and mortality. Its multifactorial pathophysiology causes a loss of pulmonary aeration during the weaning process, the clinical translation being…
- Trial name
- NCT03384394
- Testing
- high-flow nasal cannula oxygen, Conventional oxygen therapy
- Volunteers
- 250 people
- Sponsor
- lu xiao
Acute Respiratory Failure
Brain-lung Interaction During Acute Respiratory Failure
Acute hypoxemic de novo respiratory failure (AHRF) is a common cause of admission to the intensive care unit (ICU). Its main cause is community-acquired pneumonia.
- Trial name
- BrainFlow (NCT07279831)
- Testing
- EEG/NIRS/EMG
- Where
- 2 sites in France
- Volunteers
- 25 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Intensive Care, Neonatal, Neonatal Respiratory Distress Syndrome
Breastfeeding Infants Receiving Respiratory Support Trial
The purpose of this study is to assess whether two methods of breathing support in babies called 'Humidified High-Flow Nasal Cannula' oxygen (HHFNC) and 'nasal Continuous Positive Airways Pressure' (nCPAP) are compatible with…
- Conditions
- Intensive Care, Neonatal, Neonatal Respiratory Distress Syndrome, Continuous Positive Airway Pressure, Breast Feeding
- Trial name
- BIRRST (NCT02999165)
- Testing
- Breast feeding, Nasogastric feeding
- Where
- United Kingdom
- Volunteers
- 1 people
- Sponsor
- Imperial College Healthcare NHS Trust
Healthy Volunteers
Gas Composition in the Oropharynx During High-flow Oxygen Therapy Through Nasal Cannula in Healthy Volunteers
Observational, randomized studies and their meta-analyses have shown the high effectiveness of high-flow oxygen therapy through nasal cannulas, reaching 50-60% in acute hypoxemic respiratory failure.
- Trial name
- NCT06189716
- Testing
- High flow oxygen through nasal cannula
- Where
- Russia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Ventilatory Depression
Correlation of ETCO2 to PaCO2 Measured by Sentri Nasal Cannula
Sampling end tidal gas via nasal prong has been shown to be a noninvasive and reliable method of monitoring end-tidal CO2 in spontaneously breathing patients.
- Trial name
- NCT03374644
- Testing
- SentriTM ETCO2 adult nasal cannula
- Volunteers
- 40 people
- Sponsor
- University of Malaya
Hypoxemia, Pneumonia
Effect of High-Flow Nasal Cannula Oxygen Therapy on Hypoxemia in Pediatric Sedated Bronchoscopy
Due to children's lower oxygen reserves and higher oxygen consumption, sedation can easily lead to respiratory adverse events such as hypoxemia.
- Conditions
- Hypoxemia, Pneumonia, Pulmonary Neoplasm
- Trial name
- NCT07563075
- Testing
- High-flow nasal cannula, Regular Nasal Cannula
- Where
- 4 sites in China
- Volunteers
- 430 people
- Sponsor
- Zhejiang University
Respiratory Failure, Re-intubation Rate
High Flow Nasal Cannula Versus Non Invasive Positive Pressure Ventilation in Reducing The Rate of Reintubation
This is study aim to compare between high flow nasal canula (HFNC) and non invasive positive pressure ventilation (NIPPV) in reducing the rate of reintubation in mechanically ventilated patient with successful weaning
- Trial name
- NCT06029699
- Testing
- high flow nasal cannula, non invasive positive pressure ventilation
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Post Operative Pulmonary Complications
HFNC Versus Oxygen Face Mask on Postoperative Pulmonery Complications
Eighty adult patients were randomly categorized into two equal groups (forty patients each): HFNC was applied to group I, and a simple oxygen face mask was applied to group II.
- Trial name
- NCT05548309
- Testing
- HFNC, Oxygen face mask
- Where
- Egypt
- Volunteers
- 94 people
- Sponsor
- Alexandria University
Bronchopulmonary Dysplasia, Prematurity
Impact of Extended CPAP on Bronchopulmonary Dysplasia
The purpose of this pilot study is to compare if keeping infants on CPAP (continuous positive airway pressure) support for an extended period of time until they are 32 weeks corrected gestational age or 1250 grams (approximately…
- Trial name
- NCT05547139
- Testing
- Protocolized weaning of respiratory support
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Christiana Care Health Services
Continuous Positive Airway Pressure
Effect of Continuous Positive Airway Pressure Delivered by Two Different Modalities on Breathing Pattern in Preterm Infants
In this study, the investigators want to observe how continuous positive airway pressure delivered by two different modalities affects breathing pattern in small preterm infants.
- Trial name
- NCT01326975
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Sunnybrook Health Sciences Centre
Respiratory Failure With Hypoxia
Helmet Noninvasive Ventilation vs. High-flow Nasal Cannula in Moderate-to-severe Acute Hypoxemic Respiratory Failure
Helmet noninvasive ventilation and high-flow nasal cannula are novel tools for the first-line treatment of acute hypoxemic respiratory failure.
- Trial name
- HENIVOTpilot (NCT04502576)
- Testing
- Noninvasive respiratory support
- Where
- 5 sites in Italy
- Volunteers
- 110 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Head and Neck Neoplasm
Preoxygenation With a High-flow Nasal Cannula or a Simple Mask Before General Anesthesia in Head and Neck Surgery
Objectives: To assess arterial oxygen partial pressure (PaO2) at defined time points during the preoxygenation and to compare between high flow heated humidified nasal oxygen versus standard preoxygenation with oxygen insufflation…
- Trial name
- NCT03896906
- Testing
- High-flow nasal cannula, simple mask
- Where
- South Korea
- Volunteers
- 52 people
- Sponsor
- Asan Medical Center
Respiratory Distress, Lung Injury
Infant Pulmonary Mechanics: High Flow Nasal Cannula Versus Nasal CPAP
This study is designed to evaluate the effect of heated humidified high flow nasal cannula (HHHFNC) as compared to noninvasive nasal continuous positive airway pressure (NCPAP) on lung function as a measure of lung injury in…
- Trial name
- NCT01939067
- Testing
- Heated Humidified High Flow Nasal Cannula, Nasal Continuous Positive Airway Pressure
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Extreme Prematurity - Less Than 28 Weeks, Respiratory Distress Syndrome in Premature Infants
Study of Respiratory Physiology During High Flow Nasal Cannula Treatment in Preterm Neonates.
The most commonly used noninvasive respiratory support in preterm babies is Continuous Positive Airway Pressure (CPAP), which provides extra breathing support to babies who are breathing by themselves).
- Trial name
- NCT02200900
- Testing
- Pharyngeal pressure, Transcutaneous carbon dioxide, Pharyngeal gas concentrations
- Where
- United Kingdom
- Volunteers
- 45 people
- Sponsor
- Newcastle-upon-Tyne Hospitals NHS Trust
Bile Duct Carcinoma, Gallbladder Carcinoma
A Dual Channel Supraglottic Airway Device (LMA Gastro) for Oxygenation in Patients Undergoing ERCP
This clinical trial compares the effect of LMA Gastro, a dual channel supraglottic airway (SGA) device, to oxygenation with standard nasal cannula for endoscopic retrograde cholangiopancreatography (ERCP).
- Conditions
- Bile Duct Carcinoma, Gallbladder Carcinoma, Pancreatic Ductal Adenocarcinoma
- Trial name
- NCT04740164
- Testing
- Endoscopic Retrograde Cholangiopancreatography
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- M.D. Anderson Cancer Center
Post Extubation Respiratory Failure, Re-intubation
Efficacy of HFNC Versus NIV for Prevent Reintubation in Sepsis Patients
Post extubation respiratory failure occur in 30% of extubated patients. More than 50% of them required reintubation. Noninvasive positive pressure ventilation (NIV) had been reported as an effective tool to prevent post…
- Conditions
- Post Extubation Respiratory Failure, Re-intubation, Septic Shock, Severe Sepsis
- Trial name
- NCT03246893
- Testing
- Noninvasive positive pressure ventilation, High flow oxygen nasal cannula
- Where
- Thailand
- Volunteers
- 222 people
- Sponsor
- Mahidol University
Atelectasis, Postoperative Pulmonary
End-Expiratory Lung Volume in Children Awakening From Propofol Anesthesia
The goal of this pilot randomized clinical trial is to test the effects of high flow nasal oxygen and head elevation during awakening from propofol anesthesia in pediatric patients undergoing airway surgery.
- Trial name
- NCT05821114
- Testing
- Head elevation_H, Supine_H, Head elevation_L
- Where
- South Korea
- Volunteers
- 52 people
- Sponsor
- Seoul National University Hospital