Clinical trials: Nasal Congestion
Nasal Congestion
The Safety and Efficacy of a SinuSonic Intervention
This study aims to test the safety and effectiveness of the SinuSonic device on adults with moderate to severe nasal congestion.
- Trial name
- NCT03906968
- Testing
- SinuSonic Device
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Medical University of South Carolina
Cough, Sore Throat
A Study to Evaluate the Efficacy and Safety of IV Peramivir in Addition to Standard of Care Compared to Standard of Care Alone in Adults and Adolescents Who Are Hospitalized Due to Influenza
A Phase 3, multicenter, randomized, double-blind, controlled study to evaluate the efficacy and safety of peramivir administered intravenously in addition to standard of care compared to standard of care alone in adults and…
- Conditions
- Cough, Sore Throat, Nasal Congestion, Headache
- Trial name
- NCT00958776
- Testing
- Peramivir+SOC
- Where
- 196 sites in United States, Argentina and 21 more
- Volunteers
- 405 people
- Sponsor
- BioCryst Pharmaceuticals
Nasal Congestion
To Determine if Diphenhydramine Works for Nasal Congestion at Two Different Doses
The study was to determine if the drug worked to relieve nasal congestion experienced by people with seasonal allergies.
- Trial name
- NCT00648973
- Testing
- Diphenhydramine 50 mg, Diphenhydramine 25 mg, Pseudoephedrine 120 mg
- Where
- 12 sites in United States
- Volunteers
- 1,021 people
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
Obstructive Sleep Apnea, Nasal Congestion
Effect of Heated Humidity With Thermosmart™ Compared to an Intranasal Steroid in Improving Compliance and Nasal Symptoms in Patients Using Continuous Positive Airway Pressure
1. CPAP compliance will be significantly higher in both the heated humidity with Thermosmart™ and the nasal steroid phases compared to the double placebo phase. 2.
- Conditions
- Obstructive Sleep Apnea, Nasal Congestion, Sinus Congestion
- Trial name
- Thermosmart (NCT00665977)
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Clayton Sleep Insititute
Nasal Congestion, Nasal Dryness
PMCF Study to Evaluate Performance and Safety of "NASAL SPRAYS " Used to Relieve Nasal Congestion and Dryness
Acute viral upper respiratory tract infection, also known as common cold, is the most frequently observed infectious disease in human beings.
- Trial name
- NCT05843071
- Testing
- Nasal sprays with sea salts
- Where
- Italy
- Volunteers
- 105 people
- Sponsor
- C.O.C. Farmaceutici S.r.l.
Rhinitis Medicamentosa
A Study Comparing Proponent Solution - Nasal Spray (PSNS) With Salt Water for Treating Nasal Congestion Symptoms in Adults With Rebound Nasal Congestion While Weaning From Nasal Decongestant Sprays
The purpose of the study was to test if the PROPONENT® nasal spray works, if it is safe, and if it helps participants to stop using addictive nasal decongestant sprays.
- Trial name
- PROUD (NCT06817967)
- Testing
- PSNS, ISNS
- Where
- 7 sites in Norway
- Volunteers
- 194 people
- Sponsor
- Pharma Nordic AS
Allergic Rhinitis
NoAL (HPMC) in Combination With Oxymetazoline in Patients With Allergic Rhinitis
Allergic rhinitis is treated with a variety of systemic and locally applied drugs. The effectiveness of the intranasally applied formulations is diminished by the cleaning mechanisms of the nose, rhinorrhea in particular.
- Trial name
- NOPAR (NCT01986582)
- Testing
- Oxymetazoline, Hydroxyl-propyl-methyl cellulose powder
- Where
- Bulgaria
- Volunteers
- 40 people
- Sponsor
- Association Asthma, Bulgaria
Rhinitis, Allergic, Perennial
LEADER (LEvocetirizine And DEsloratadine in Allergic Rhinitis)
Two weeks study to evaluate the efficacy and safety of Levocetirizine and Desloratadine in patients suffering from Allergic Rhinitis (AR)
- Trial name
- NCT00160589
- Testing
- Levocetirizine
- Volunteers
- 729 people
- Sponsor
- UCB Pharma
Nasal Congestion
A User Study of the Soniflow System for Nasal Congestion Relief
The Soniflow System consists of an acoustic vibrational headband paired with a Smartphone App to provide rapid relief of nasal congestion.
- Trial name
- NCT04910139
- Testing
- Soniflow System
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Third Wave Therapeutics
Nasal Congestion, Nasal Obstruction
A Study to Learn More About How Well Oxymetazoline HCl 0.05% Nasal Gel Works and How Safe It Is in Healthy Adults
Nasal congestion (a "stuffy nose") is a common symptom of colds and seasonal or year-round allergies. It happens when the tiny blood vessels and tissues inside the nose swell and leak fluid, producing more mucus.
- Trial name
- NCT07582328
- Testing
- Oxymetazoline HCl 0.05% nasal gel
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Bayer
Upper Respiratory Tract Infection, Nasal Congestion
Evaluation of Efficacy and Safety of Tablets of Paracetamol, Dimethindene Maleate and Phenylephrine Hydrochloride in Reducing Symptoms of Common Cold and Flu
The study is a clinical evaluation of an over the counter (OTC) combination product containing paracetamol (500 mg), dimethindene maleate (1 mg), phenylephrine hydrochloride (10 mg) compared to paracetamol (500 mg) alone in the…
- Conditions
- Upper Respiratory Tract Infection, Nasal Congestion, Rhinorrhea, Sneezing
- Trial name
- NCT01448057
- Testing
- Paracetamol (500 mg)/dimethindene maleate (1 mg)/ phenylephrine hydrochloride (10 mg) tablets, Paracetamol (500 mg) tablets
- Where
- 6 sites in Brazil
- Volunteers
- 341 people
- Sponsor
- Novartis
Nasal Congestion
A Study to Compare Two Formulations of Xylometazoline/Dexpanthenol Nasal Spray for the Treatment of Nasal Congestion.
An observer-blind, multi-centre, randomized, parallel-group study to compare the efficacy and safety of two formulations of xylometazoline/dexpanthenol nasal spray for the treatment of nasal congestion caused by an acute upper…
- Trial name
- NCT03439436
- Testing
- xylo+dex nasal spray (0.1 mg+5 mg/dose), Nasic
- Where
- 5 sites in Russia
- Volunteers
- 140 people
- Sponsor
- McNeil AB
Allergic Rhinitis
Intranasal Steroids and Oxymetazoline in Allergic Rhinitis
We hypothesize that once daily use of oxymetazoline will not cause significant rhinitis medicamentosa and that the combination of fluticasone furoate plus oxymetazoline leads to faster relief of nasal congestion secondary to…
- Trial name
- NCT00584987
- Testing
- Fluticasone furoate, Oxymetazoline
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Covid19, Nasopharyngitis
BNO 1030 Extract (Imupret) in the Treatment of Mild Forms of COVID-19
According to WHO (World Health Organisation) data, about 40% of patients with COVID-19 (Corona Virus SARS-CoV-2) have a mild course of the disease, namely, cases of mild course are of great danger from the point of view of the…
- Conditions
- Covid19, Nasopharyngitis, Anosmia, Fever
- Trial name
- NCT04797936
- Testing
- BNO 1030, Standard care
- Where
- Ukraine
- Volunteers
- 133 people
- Sponsor
- Ivano-Frankivsk National Medical University
Allergic Rhinitis
Assess the Efficacy and Safety of Rhinocort Aqua
The purpose of this study is to compare Rhinocort with placebo in pediatric subjects aged 2-5 years with allergic rhinitis to study effects on nasal symptoms such as sneezing, runny and stuffy noses.
- Trial name
- NCT00641693
- Testing
- Budesonide
- Volunteers
- 650 people
- Sponsor
- AstraZeneca
Allergic Rhinitis
Acupuncture for Nasal Congestion in Allergic Rhinitis
Allergic rhinitis (AR) is a disorder that affects more than 500 million people worldwide. Nasal congestion is one of the most general and bothersome symptoms in rhinitis, which impacts the quality of life (QOL).
- Trial name
- ANCAR (NCT05709977)
- Testing
- Acupuncture, Antihistamine nasal spray
- Where
- Netherlands
- Volunteers
- 11 people
- Sponsor
- Johanna Maria Vermeulen
Allergic Rhinitis, Allergic Rhinoconjunctivitis
Demonstration of a Decongestant Effect of "Coldamaris Akut" Compared to Saline Nasal Spray.
Allergic rhinitis (AR) in its seasonal and perennial form is a common allergic condition. The majority of allergic rhinitis sufferers report nasal (congestion, sneezing, itching and rhinorrhea) and ocular (redness, watery eyes…
- Trial name
- NCT04532762
- Testing
- nasal spray
- Where
- Austria
- Volunteers
- 42 people
- Sponsor
- Marinomed Biotech AG
Common Cold, Headache
Efficacy and Safety of Sinutab on Subjects in the Setting of a Common Cold
The purpose of this study is to investigate the efficacy and safety for a marketed sinus allergy product, Sinutab, in the treatment of nasal congestion and headache.
- Conditions
- Common Cold, Headache, Nasal Congestion
- Trial name
- NCT00378144
- Testing
- Pseudoephedrine/Paracetamol
- Where
- Belgium
- Volunteers
- 469 people
- Sponsor
- McNeil AB
Nasal Congestion and Inflammations, Rhinitis
Efficacy and Safety of Combination of Brompheniramine and Phenylephrine for the Symptoms Relief of Rhinitis
This is a multicenter clinical trial, phase III, superiority, controlled by active medicine, double-blind, randomized, enroll 166 children, over 12 years old, with acute inflammation upper airway, characterized by nasal…
- Trial name
- NCT01393561
- Testing
- Group 1, Group 2
- Volunteers
- 167 people
- Sponsor
- Ache Laboratorios Farmaceuticos S.A.
Seasonal Allergic Rhinitis
Effects of Phenylephrine Extended-Release Tablets on Allergy-Related Nasal Congestion (P08498 AM1)
This study will compare the nasal congestion symptom relief of phenylephrine extended release tablets and placebo in participants with allergic rhinitis.
- Trial name
- NCT01413958
- Testing
- Phenylephrine, Loratadine
- Volunteers
- 575 people
- Sponsor
- Bayer