Clinical trials: Nasal Obstruction
Nasal Obstruction
The Effect of Nasal Hair on Nasal Obstruction
Nasal obstruction is a common complaint prompting presentation to an otolaryngologist. Many studies have been performed quantifying and describing the impact of a number of factors on symptoms of nasal obstruction, including…
- Trial name
- NCT01850511
- Testing
- Vibrissae trimming, Application of oxymetazoline
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Nasal Congestion
Bioequivalence of Single Dose Phenylephrine Extended Release Tablets and Phenylephrine HCl Immediate Release Tablets Dosed Every Four Hours (P08340)(COMPLETED)
This study will assess the food-effect bioavailability of an extended release formulation of phenylephrine HCl and its bioequivalence to the marketed immediate release phenylephrine HCl product.
- Trial name
- NCT01354418
- Testing
- Phenylephrine HCl Extended Release, Phenylephrine HCl Immediate Release
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Bayer
Nasal Obstruction, Septoplasty Surgeries
Effects of Surgical Correction of Nasal Obstruction on Oxygen Uptake and Ventilation Volume
This retrospective study aims to evaluate the effect of surgical correction of nasal obstruction on aerobic performance parameters in male athletes aged 20-32 years.
- Conditions
- Nasal Obstruction, Septoplasty Surgeries, Athletic Performance
- Trial name
- NCT06957262
- Testing
- Surgical correction of nasal obstruction
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Tuba Melekoğlu
Nasal Obstruction
Design and Application of Vitamin D Films for Burn Healing After Cauterizing Surgery
One of this method's drawbacks is the healing of cauterized cartilage after processing. It was reported that the healing is so slow as no dosage form can reach this place in addition to the scares produced from healing is very…
- Trial name
- NCT05142072
- Testing
- Vitamin D3
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Deraya University
Nonallergic Irritant Rhinitis
Intranasal Capsaicin Treatment for Non-Allergic Irritant Rhinitis
The proposed study seeks to investigate the effect of intranasal capsaicin treatment in patient with Non-allergic irritant rhinitis (NAIR), as well as evaluate optical rhinometry (ORM) as a means to quantify symptomatic…
- Trial name
- NCT02493257
- Testing
- Capsaicin
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Primary Acquired Nasolacrimal
Endo-nasal Endoscopic DCR and External-DCR in Primary Nasolacrimal Duct Obstruction
All patients with epiphora or eye discharge that admitted to our ophthalmic plastic clinic in Farabi hospital will be systemically evaluated.
- Trial name
- NCT02993770
- Testing
- Endoscopic DCR, External DCR
- Where
- Iran
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Tehran University of Medical Sciences
Nasal Obstruction, Deviated Nasal Septum
Diagnosis of Respiratory Disorders by the Numerical Modeling.
Chronic Nasal obstruction (CNO) is not currently measurable objectively because clinicians use validated declarative self-questionnaires whose results are linked to the level of understanding, the acute or chronic clinical…
- Trial name
- JUNE (NCT06670261)
- Testing
- Data collection
- Where
- France
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Nasal Obstruction, Bilateral
Effects of Preservation Rhinoplasty Nasal Valve Angle and Area
The study planned to compare the internal nasal valve angle measurements of patients who underwent preservation rhinoplasty before and after surgery.
- Trial name
- NCT06264089
- Testing
- Preservation Rhinoplasty Nasal Valve Angle and Area
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Rhinoplasty, Nasal Obstruction
The Role of Spreader Grafts in Reduction Rhinoseptoplasty: a Randomized Clinical Trial With Quality of Life Assessment
Nasal obstruction is one of the majors concerns in reduction rhinoseptoplasty, because it affects quality of life and surgical outcomes.
- Trial name
- NCT04499469
- Testing
- Spreader Graft
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Nasal Obstruction, Septal Defect
Does Batten Grafting Improve Nasal Outcomes in Septoplasty and Turbinate Reduction?
The objective of this study is to compare the effectiveness of batten grafts plus septoplasty and turbinate reduction (intervention arm) compared to septoplasty and turbinate reduction alone (control arm), both in terms of…
- Conditions
- Nasal Obstruction, Septal Defect, Allergic Rhinitis, Nasal Polyps
- Trial name
- NCT05287841
- Testing
- Batten batten graft, Septoplasty, Inferior Turbinate Reduction
- Where
- 3 sites in United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Nasal Congestion
Bioequivalence Between Two Oral Formulations of Diphenhydramine Hydrochloride
The purpose of this study is to determine if two formulations of diphenhydramine hydrochloride are bioequivalent.
- Trial name
- NCT00662337
- Testing
- Diphenhydramine hydrochloride
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
Eustachian Tube Dysfunction, Hearing Disorders
FFP3 Respirators and Ears - Effects on Middle Ear Pressure and Hearing
This is Prospective Basic Science Study whose aims are as follows: 1. To determine the effect of Filtering Facepiece (FFP3M) respirators on eustachian tube function and hearing 2.
- Conditions
- Eustachian Tube Dysfunction, Hearing Disorders, Nasal Obstruction
- Trial name
- FFP3-RAE (NCT05222230)
- Testing
- FFP3 Mask
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Liverpool University Hospitals NHS Foundation Trust
Allergic Rhinitis
Effects of AkPharma's Calcium Glycerophosphate Nasal Spray Wash
Over 20 million Americans have allergic nasal symptoms including stuffiness, sneezing and a "runny" nose. AkPharma's Calcium Glycerophosphate used as a nasal spray wash is believed to improve these symptoms without side effects…
- Trial name
- NCT01647633
- Testing
- Calcium Glycerophosphate Nasal Spray Wash
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Drexel University
Nasal Obstruction
A New Treatment for Mechanical Nasal Obstruction
The research team has developed a prototype for an investigational mechanical nasal dilator and the investigators aim to evaluate its efficacy.
- Trial name
- NCT03456115
- Testing
- Mechanical nasal dilator
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Nasal Obstruction
Nasal Obstruction and Olfactory Losses
About 13% of US adults, some 30 million people, suffer from nasal sinus disease. Although nasal obstruction and smell loss are two of the major symptoms of the disease that are crucial to disease management, currently there is a…
- Trial name
- NCT05920330
- Testing
- Nasal Plug
- Where
- United States
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Nasal Obstruction
Impact of External Nasal Dilator on the Rhinogram
The aim of this study is to present new data for a better understanding of the anatomic correlation of these two notches. This study included 32 nasal cavities (16 individuals) with external nasal dilator strip (Breath Right®)…
- Trial name
- ARENDS (NCT01411969)
- Testing
- External Nasal Dilator Strip; 0.05% oxymetazoline chloride
- Where
- Brazil
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Nasal Congestion
Functional Magnetic Resonance Imaging (fMRI) Study of Nasal Strips in Nasal Congestion
The aim of the study is to evaluate the effect of the nasal strip (relative to the placebo strip) on the nasal passages using anatomical MRI scans and to demonstrate the effect of the strip on breathing correlated cortical…
- Trial name
- NCT02275364
- Testing
- Test strip, Nasal spray
- Where
- United Kingdom
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Nasal Obstruction
Hypnosis to Perform Awake Intubation
Awake intubation is a recommended safety procedure in specific cases where the intubation or ventilation before general anesthesia is at risk.
- Trial name
- Hypnotube (NCT02513511)
- Testing
- laryngoscopy under hypnosis
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Lausanne Hospitals
Nasal Obstruction
Trial Comparing Microdebrider-Assisted Inferior Turbinoplasty (MAIT) vs Submucous Resection (SMR)
This is a prospective, patient blinded, randomized, clinical trial enrolling patients with symptoms and signs of nasal obstruction related to enlarged inferior turbinates.
- Trial name
- NCT02695602
- Testing
- Microdebrider-Assisted Inferior Turbinoplasty (MAIT), Submucous Resection with non powered instrument
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Nasal Congestion, Nasal Obstruction
A Study to Learn More About How Well Oxymetazoline HCl 0.05% Nasal Gel Works and How Safe It Is in Healthy Adults
Nasal congestion (a "stuffy nose") is a common symptom of colds and seasonal or year-round allergies. It happens when the tiny blood vessels and tissues inside the nose swell and leak fluid, producing more mucus.
- Trial name
- NCT07582328
- Testing
- Oxymetazoline HCl 0.05% nasal gel
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Bayer