Clinical trials: Nasal Obstruction
Nasal Airway Obstruction
Thermal Imaging as a Potential Diagnostic Tool of Nasal Airflow
Currently, there are no tools that can measure nasal airflow in an objective manner that is non-invasive to the patient. This clinical study aims to address this by evaluating the use of thermal imaging as a diagnostic tool for…
- Trial name
- NCT03233373
- Testing
- Seek CompactPro thermal imager
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- New York City Health and Hospitals Corporation
Pulmonary Disease, Chronic Obstructive
The Nasal Airway in Chronic Obstructive Pulmonary Disease
The study is based on the theory of a "unified airway" that considers the nose and paranasal sinuses together with lower airways as one integrated unit.
- Trial name
- COPD (NCT02826954)
- Testing
- Upper airway assessment, including nasal biopsy
- Where
- Norway
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Nasal Obstruction
A New Treatment for Mechanical Nasal Obstruction
The research team has developed a prototype for an investigational mechanical nasal dilator and the investigators aim to evaluate its efficacy.
- Trial name
- NCT03456115
- Testing
- Mechanical nasal dilator
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Nasal Congestion
Functional Magnetic Resonance Imaging (fMRI) Study of Nasal Strips in Nasal Congestion
The aim of the study is to evaluate the effect of the nasal strip (relative to the placebo strip) on the nasal passages using anatomical MRI scans and to demonstrate the effect of the strip on breathing correlated cortical…
- Trial name
- NCT02275364
- Testing
- Test strip, Nasal spray
- Where
- United Kingdom
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Nasal Obstruction
Hypnosis to Perform Awake Intubation
Awake intubation is a recommended safety procedure in specific cases where the intubation or ventilation before general anesthesia is at risk.
- Trial name
- Hypnotube (NCT02513511)
- Testing
- laryngoscopy under hypnosis
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Lausanne Hospitals
Nasal Obstruction
Analysis of Impact on Nasal Obstruction by Commercially Available Internal Nasal Stents
Commercially-available internal nasal stents placed inside the nostril should produce decreased nasal obstruction detectable subjectively (volunteers will fill out a survey) and objectively (degree of obstruction will be measured…
- Trial name
- NCT00683254
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Bethany L. Jones
Nasal Congestion
A Nasal Spray for Relief of Nasal Congestion in Infants and Toddlers With Common Cold
The study will evaluate the safety and efficacy of the study medical device plus standard of care versus standard of care in subjects between 3 and 48 months (inclusive) presenting symptoms of a common cold.
- Trial name
- NCT05365789
- Testing
- Blocked Nose Baby nasal spray, Standard of care
- Where
- Poland
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Church & Dwight Company, Inc.
Obstructive Sleep Apnoea Syndrome, Nasal Obstruction
Nasal Obstruction in Sleep Apnea Patients Compared to the General Population
Recent clinical findings of research at Trondheim University Hospital suggest that surgical correction of the nose septum in addition to volume reduction of the nose cavity may be beneficial in patients who suffer from both nose…
- Trial name
- NCT01282125
- Where
- Norway
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Nasal Obstruction, Nasal Disease
Impact of Nasal Isotonic Solution Irigation on Healthy Athletes' Nasal Flow and Nasal Obstruction Exercise Outcomes
Nasal patency is an important component of performing exercises because it helps in humidifying, heating and filtering the inhaled air.
- Trial name
- ISOtastic! (NCT05948800)
- Testing
- Nasal irrigation with seawater isotonic solution
- Where
- Croatia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital Sestre Milosrdnice
Nasal Obstruction
The Effect of Nasal Hair on Nasal Obstruction
Nasal obstruction is a common complaint prompting presentation to an otolaryngologist. Many studies have been performed quantifying and describing the impact of a number of factors on symptoms of nasal obstruction, including…
- Trial name
- NCT01850511
- Testing
- Vibrissae trimming, Application of oxymetazoline
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Drug Use
Regional Nasal Block and Dexmedetomidine in Endoscopic Sinus Surgery
The purpose is to compare the efficacy of combined regional nasal block and general anesthesia versus general anesthesia with dexmedetomidine during endoscopic sinus surgery in optimizing intraoperative surgical field.
- Trial name
- NCT05361642
- Testing
- Bupivacaine HCl 0.5% Injectable Solution, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Apnea, Airway Obstruction, Nasal
Upper Airway's Pressure Drop Analyses After Mandibular Advancement and Maxillary Expansion
Breathing is a crucial function for everyone. Breathing impairment in children could lead to behavioral and cognitive problems at least.
- Conditions
- Apnea, Airway Obstruction, Nasal, Mandible Small, Maxillary Hypoplasia
- Trial name
- NCT04190953
- Testing
- Twin block then Hyrax, Hyrax then Twin block
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Nasal Obstruction, Rhinoplasty
Inferior Turbinate Surgery in Rhinoseptoplasty: a Randomized Clinical Trial With Quality of Life Outcomes
The purpose of this study is to determine whether inferior turbinate surgery during rhinoseptoplasty is effective in improving quality of life and acoustic rhinometry outcomes.
- Conditions
- Nasal Obstruction, Rhinoplasty, Rhinoseptoplasty, Turbinate Surgery
- Trial name
- NCT01457638
- Testing
- Inferior turbinate surgery, No iInferior turbinate surgery
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Nasal Congestion, Nursing
Effects of Different Nasal Irrigation Methods on Pain Level, Crying and Procedure Times in Nasal Congestion in Infants
This study aimed to evaluate the effects of different nasal irrigation (NI) methods for relieving nasal obstruction on pain, crying and procedure times, and physiologic parameters in infants with acute upper respiratory tract…
- Trial name
- NCT06691620
- Testing
- Nasal irrigation with isotonic saline, Nasal irrigation with hypertonic saline, Nontraumatic nasopharyngeal aspiration
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Allergic Rhinitis
Effects of AkPharma's Calcium Glycerophosphate Nasal Spray Wash
Over 20 million Americans have allergic nasal symptoms including stuffiness, sneezing and a "runny" nose. AkPharma's Calcium Glycerophosphate used as a nasal spray wash is believed to improve these symptoms without side effects…
- Trial name
- NCT01647633
- Testing
- Calcium Glycerophosphate Nasal Spray Wash
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Drexel University
Nasal Obstruction, Bilateral
Effects of Preservation Rhinoplasty Nasal Valve Angle and Area
The study planned to compare the internal nasal valve angle measurements of patients who underwent preservation rhinoplasty before and after surgery.
- Trial name
- NCT06264089
- Testing
- Preservation Rhinoplasty Nasal Valve Angle and Area
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Agitation States as Acute Reaction to Gross Stress
Efficacy of External Nasal Nerve Block in Prevention of Postoperative Agitation Following Nasal Surgeries
Emergence agitation following general anaesthesia may lead to serious complications like self-extubation or removal of catheters, which can lead to hypoxia, aspiration pneumonia, bleeding or reoperation.
- Trial name
- NCT03069027
- Testing
- External nasal nerve block, saline adrenaline, Xylocaine, adrenaline
- Where
- Saudi Arabia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Al Jedaani Hospital
Septal Deformity, Nasal Obstruction
Clinical Extend Study to Evaluate Safety and Effectiveness of TnR Nasal Mesh for Correction of Nasal Septum on Patients
The purpose of this observation study is to evaluate long term safety and efficacy at 2~3 years after surgery on patients who have completed nasal septal deformity surgery using TnR Nasal Mesh.
- Trial name
- NCT04332575
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- T&R Biofab Co., Ltd.
Nasal Obstruction, Septoplasty Surgeries
Effects of Surgical Correction of Nasal Obstruction on Oxygen Uptake and Ventilation Volume
This retrospective study aims to evaluate the effect of surgical correction of nasal obstruction on aerobic performance parameters in male athletes aged 20-32 years.
- Conditions
- Nasal Obstruction, Septoplasty Surgeries, Athletic Performance
- Trial name
- NCT06957262
- Testing
- Surgical correction of nasal obstruction
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Tuba Melekoğlu
Nasal Septum; Deviation, Congenital, Nasal Obstruction
Suture-based, Minimally Invasive Technique Used to Correct NSD
Nasal Septal Deviation (NSD) is one of the most common indications for surgery seen by ENT physicians, however, correction requires open surgery which is associated with several weeks of recovery.
- Trial name
- NCT04891263
- Testing
- Suture-Septoplasty, Surgical suture
- Where
- 2 sites in United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Stanford University