Clinical trials: Nasal Septum Perforation
Nasal Septum Perforation
Nasal Septal Flap for Donor Site Reconstruction
The purpose of this study is to demonstrate the utility of porcine small intestinal submucosa (SIS) as a graft material that may aid in the natural healing process of freshly exposed bone and cartilage in the nasal cavity.
- Trial name
- NCT03159624
- Testing
- Biodesign™ SIS graft, Doyle silastic sheet
- Volunteers
- 47 people
- Sponsor
- University of Alabama at Birmingham
Nasal Septal Perforation
Oral Mucosal Grafting for Nasal Septal Perforation Repair
This study will assess how often a hole in the nasal septum (the wall separating the two sides of the nose), closes completely after surgical repair using tissue taken from the lining of the patient's own mouth.
- Trial name
- NCT07902856
- Testing
- Nasal Septal Perforation Repair With an Autologous Oral Mucosal Graft
- Where
- 3 sites in Spain
- Volunteers
- 46 people
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Nasal Perforated Septum
New Method to Close Nasal Septal Perforation
The goal of this clinical trial is to investigate if a 3-dimensional fabricated nasal mesh works to close nasal septal perforations.
- Trial name
- NCT06439927
- Testing
- Polycaprolactone nasal mesh
- Where
- Egypt
- Volunteers
- 23 people
- Sponsor
- Helwan University
Chronic Nasal Septum Perforation
Collagen Membrane Combined With HUC-MSCs Transplantation in Patients With Nasal Septum Perforation
The purpose of this study is to assess the safety and efficacy of collagen membrane combined with human clinical grade umbilical cord mesenchymal stem cells(HUC-MSCs) transplantation in patients with chronic nasal septum…
- Trial name
- NCT02947191
- Testing
- Collagen membrane + HUC-MSCs
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Chinese Academy of Sciences
Nasal Cartilage Septum Perforations
Nasal Septum Perforation Treatment Using Tissue Engineered Cartilage Graft
The purpose of this study is to investigate the safety and feasibility of implanting an engineered cartilage tissue in an interposition graft with a temporoparietal fascia (TPF) flap to repair medium size septal perforation.
- Trial name
- NSP (NCT04633928)
- Testing
- N-TEC: Autologous nasal chondrocytes and ECM proteins
- Where
- Switzerland
- Volunteers
- 5 people
- Sponsor
- University Hospital, Basel, Switzerland