Clinical trials: Nasal Surgical Procedures
Emergence Agitation, Nasal Surgery
Emergence Agitation
The impact of sugammadex on agitation upon emergence following adult nasal surgeries is an issue which needs to be studied that links anesthetic management with postoperative recovery.
- Trial name
- Sugamadex (NCT07253428)
- Testing
- Neostigmine + Atropine, Sugamadex
- Where
- Saudi Arabia
- Volunteers
- 486 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Chronic Rhinosinusitis (CRS) with and Without Nasal Polyps
Correlation of Preoperative Indices (serum Vit D, Calcium, Phosphorus, FAR, PLR, SII) on Intraoperative Bleeding in CRS
The purpose of this observational study was to examine whether preoperative indicators correlate with intraoperative bleeding to facilitate control of intraoperative bleeding.
- Trial name
- NCT06737198
- Testing
- without interventios.
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Emergence Agitation
The Effect of Oral Gabapentin on Emergence Agitation and Delirium in Adult Patients After Nasal Surgery.
Emergence agitation is a postanesthetic phenomenon that develops in the early phase of recovery from general anesthesia, and is characterized by agitation, disorientation, confusion, and possible violent behavior.
- Trial name
- NCT06887998
- Testing
- Gabapentin 600 mg capsules, Gabapentin 400 mg capsules
- Where
- Egypt
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Cairo University
Septal Deformity, Nasal Obstruction
A Clinical Study to Evaluate the Safety and Efficacy of Surgical Material for Nasal Septoplasty
The purpose of this clinical trial is to evaluate safety and efficacy of TnR mesh for patients who need nasal septoplasty for septal deformity with nasal obstruction.
- Trial name
- NCT03088618
- Testing
- Nasal septoplasty
- Where
- 2 sites in South Korea
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- T&R Biofab Co., Ltd.
Emergence Agitation
Efficacy of Remifentanil in Preventing Emergence Agitation
The primary aim of the study was to test the hypothesis that remifentanil administered for analgesia prevents emergence agitation more effectively than fentanyl and N2O in patients undergoing rhinoplasty who received desflurane…
- Trial name
- agitation (NCT06539013)
- Testing
- Remifentanil, N2O, Fentanyl
- Where
- Turkey (Türkiye)
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Airway Complication of Anesthesia
Role of Airway Topicalization in Awake Fiberoptic Intubation
Airway management is an integral part of general anesthesia. Difficult airway management may lead to various adverse events such as airway trauma, up to cardiopulmonary arrest.
- Trial name
- NCT06720220
- Testing
- Dexmedetomidine Hydrochloride, Nebulization, Atomization
- Where
- Egypt
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Nasal Defect
Non-Surgical Rhinoplasty Using PDO Threads
To determine the effects of absorbable Polydioxanone (PDO) thread non-surgical revision rhinoplasty on first impressions and quality of life (FACE-Q scale) in 10 patients who desire further changes to their nasal tip and/or nasal…
- Trial name
- NCT04769427
- Testing
- PDO max threads
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- DeNova Research
Nursing Caries
The Effect of Brochure-Based Education on Patients Planned for Nose Surgery
The study was planned as a randomized controlled trial to determine the effect of brochure-based education on fear and anxiety in patients scheduled for nose surgery.It is planned to collect research data in Hatay Mustafa Kemal…
- Trial name
- NCT05388799
- Testing
- Educational intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Agitation
Midazolam Effect on Agitation Postnasal Surgery
Postoperative agitation is a common complication, it's incidence post head and neck surgery is around 11-26%. Avoiding such complication is mandatory to facilitate patient's recovery and reduce risk of postoperative agitation…
- Trial name
- NCT05165914
- Testing
- Intravenous midazolam before emergence from general anesthesia, Intravenous normal saline before emergence from general anesthesia
- Where
- Jordan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Jordanian Royal Medical Services
To Evaluate PSQ as Clinical Tool in the Decision Between Medical and Surgical Treatment for Adenotonsillar Hypertrophy, To Determine Clinical Response to Montelukast or Nasal Steroids Based on PSQ Results
Medical vs Surgical Treatment in OSA Among Children
Adeno-tonsillar hypertrophy causing OSA are treated surgically however, over the last years it has been shown that montelukast or nasal steroidal spray can significantly improve symptoms, adenoid size, and polysomnographic…
- Trial name
- NCT05651750
- Testing
- Montelukast, Fluticasone Furoate
- Where
- Israel
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Postoperative Agitation
The Effect of Preoperative Counseling on Emergence Agitation in Patients Candidate for Nasal Surgeries
Emergence agitation is a post anesthetic phenomenon that develops in the early phase of general anesthesia recovery,The aim of our study to investigate the effect of preoperative educational counselling of the patient undergoing…
- Trial name
- NCT06686511
- Where
- Egypt
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- Cairo University
Facial Deformity, Implant Complication
Optimizing Surgical and Prosthetic Workflow for Implant-supported Ear and Nose Prostheses With Early Loading and Distant Prosthesis Fabrication: A Prospective Cohort Study
Facial defects created by trauma, oncological procedures or congenital conditions can be repaired with ear, nose and/or eye prostheses. These are fixed on intraosseous implants placed in the temporal, nasal and orbital bone.
- Trial name
- NCT06506695
- Testing
- Craniofacial implant placement
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Peripheral Perfusion, Postoperative Pain
Effects Magnesium Sulfate and Labetalol Infusion on Peripheral Perfusion and Pain in Nasal Surgeries
One of main risk of controlled hypotension during nasal surgeries is impaired perfusion. Peripheral perfusion of non-vital organs usually impaired earlier than vital organs.
- Trial name
- NCT04688203
- Testing
- Magnesium Sulfate Injection, Labetalol Injectable Solution
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Sore-throat, Nasopharyngeal Pack
Effect of Oropharyngeal Pack Soaked in Ketamine or Magnesium Sulphate on Post Operative Sore Throat After Nasal Surgery
The aim of this study is to compare the effect of ketamine or magnesium sulphate soaked throat pack on the incidence and severity of post operative sore throat as a primary outcome, post operative nausea and vomiting as a…
- Conditions
- Sore-throat, Nasopharyngeal Pack, Nasal Surgery, Nausea and Vomiting, Postoperative
- Trial name
- NCT05714540
- Testing
- Ketamine Hydrochloride ,Magnesium sulphate and saline 0.9%
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Nasal Obstruction, Septoplasty Surgeries
Effects of Surgical Correction of Nasal Obstruction on Oxygen Uptake and Ventilation Volume
This retrospective study aims to evaluate the effect of surgical correction of nasal obstruction on aerobic performance parameters in male athletes aged 20-32 years.
- Conditions
- Nasal Obstruction, Septoplasty Surgeries, Athletic Performance
- Trial name
- NCT06957262
- Testing
- Surgical correction of nasal obstruction
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Tuba Melekoğlu
Oxygen, pH
Comparison of the Effects of High-flow Nasal Cannula Oxygen and Jet Ventilation Techniques
Endoscopic microsurgical procedures of the larynx (direct examination-bx, microlaryngeal resection) require the anesthesiologist and surgeon to work in the same area throughout the procedure, and while ventilation is provided…
- Conditions
- Oxygen, pH, End-tidal Carbon Dioxide
- Trial name
- NCT05746949
- Testing
- oxygenization techniques
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Diagnostic, Procedures and Surgeries on or Through Accessible Mucous Membranes
Topical Application of Cocaine HCl 4% and 10% on Safety and Efficacy in Local (Topical) Anesthesia
This study aims to evaluate topical application of Cocaine HCl 4% and 10% on safety and efficacy in local (topical) anesthesia for diagnostic procedures and surgeries on or through accessible mucous membranes of the nasal…
- Conditions
- Diagnostic, Procedures and Surgeries on or Through Accessible Mucous Membranes, of the Nasal Cavities
- Trial name
- NCT01746940
- Testing
- Cocaine HCl 4% Topical Solution, Cocaine HCl 10% Topical Solution
- Where
- 2 sites in United States
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Lannett Company, Inc.
Surgical Wound
Reconstruction Flaps for Nasal Surgical Wounds RCT
The purpose of this study is to determine whether there is a significant difference in aesthetic and functional outcomes between nasalis sling flaps and lobed flaps of nasal tip wounds requiring reconstruction.
- Trial name
- NCT04729231
- Testing
- Nasalis Sling Flap, Lobed Transposition Flap
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Northwestern University
Healthcare Associated Infection, Nosocomial Infection
Red Light Photobiomodulation and Topical Disinfectants
The goal of this clinical trial is to evaluate the potential effects of photobiomodulation when used with topical disinfectants in the anterior nares of healthy adults.
- Conditions
- Healthcare Associated Infection, Nosocomial Infection, Surgical Site Infection
- Trial name
- NCT05797818
- Testing
- Methylene Blue Only, Chlorhexidine Gluconate Only, Methylene Blue + Chlorhexidine Gluconate
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Ondine Biomedical Inc.
Nasal Surgery
Pain Control for Undergoing Costal Cartilage Harvesting
The purpose of this study is to find out whether injecting the U.S. Food and Drug Administration (FDA) approved drug EXPAREL®, a long acting (approximately 96 hours) numbing medication, will reduce pain after rib cartilage…
- Trial name
- NCT05285566
- Testing
- Exparel, Xylocaine
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic