Clinical trials: Nasolabial Fold Correction
Aging Problems
Effect of a New HA Filler in Correcting Nasolabial Fold
The investigators aimed to evaluate the efficacy and safety of new HA filler for nasolabial fold correction
- Trial name
- NCT06574750
- Testing
- CUREAⓇ (ARIBIO, Ltd., Seoul, Republic of Korea), JuvedermⓇ (Q-Med AB, Uppsala, Sweden)
- Where
- South Korea
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Nasolabial Fold, Safety
A Study to Evaluate the Performance and Safety of GP0045 for Correction of Moderate to Severe Nasolabial Folds
This is a study to assess the performance and safety of GP0045 when injected in the nasolabial folds. There is an 18 months follow up period.
- Trial name
- NCT03300466
- Testing
- GP0045, Comparator
- Where
- Sweden
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Nasolabial Folds Correction, Pain
Safety and Efficacy Study of Lidocaine Mixed Hyaluronate on Nasolabial Folds Correction
This clinical trial is a double-blind, randomized, within-subject controlled, 2-armed, single-center study sponsored by SciVision Biotech Inc. and approved by National Taiwan University Hospital Research Ethics Committee.
- Trial name
- NCT02006173
- Testing
- Lidocaine, Normal Saline
- Where
- Taiwan
- Volunteers
- healthy volunteers welcome
- Sponsor
- SciVision Biotech Inc.
Nasolabial Fold
A Clinical Study to Evaluate the Efficacy and Safety of the Injection With UNIVELO Sub-Q, as Compared to Restylane® Sub-Q, in the Temporary Correction of the Nasolabial Fold
A 48-week, single-center, randomized, patient \& evaluator-blind, matched pairs, active-controlled, non-inferiority, confirmatory design
- Trial name
- NCT07150273
- Testing
- UNIVELO Sub-Q 2mL, Restylane Sub-Q 2mL
- Volunteers
- 65 people
- Sponsor
- Jetema Co., Ltd.
Nasolabial Folds
Extension Study for 43USSA1705
To evaluate the long-term safety of Sculptra Aesthetic as a single regimen for correction of Nasolabial Fold (NLF) contour deficiencies after changes in reconstitution and injection procedures compared to the approved label.
- Trial name
- NCT04225273
- Testing
- Sculptra Aesthetic, Lidocaine HCL
- Where
- 4 sites in United States
- Volunteers
- 38 people
- Sponsor
- Galderma R&D
Nasolabial Fold
Efficacy and Safety Study of Neuramis in Correction of Nasolabial Fold
This study design is a randomized, multi-center, double Masked, matched Pairs, active-controlled clinical trial. Subjects who voluntarily signed the informed consent and are judged to be eligible for this study will be…
- Trial name
- NCT01585220
- Testing
- HA filler
- Where
- 2 sites in South Korea
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Medy-Tox
Nasolabial Fold Correction
Evaluation of Efficacy and Safety of Intella Dermal Filler in Moderate to Severe Nasolabial Folds
This single-arm, before-and-after clinical trial evaluated the safety and efficacy of Intella, a combined CaHA and HA dermal filler manufactured by Espad Pharmed Darou Co., for the correction of moderate to severe nasolabial…
- Trial name
- NCT07102537
- Testing
- Hyaluronic acid combined with calcium hydroxyapatite injection
- Where
- Iran
- Volunteers
- 30 people
- Sponsor
- Espad Pharmed
Correction of Nasolabial Folds
Clinical Study to Evaluate the Efficacy and Safety of Dermalax(Deep) in Correction of Nasolabial Folds
The study is to verify that Dermalax (Deep) is not inferior to the reference device, Restylane®, in terms of efficacy and safety in the correction of nasolabial folds.
- Trial name
- NCT02179619
- Testing
- Dermalax(Deep), Restylane
- Where
- 2 sites in South Korea
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Across Co., Ltd.
Nasolabial Fold Correction, Facial Aging
Bridging Technique Validation for Nasolabial Folds JN-BRIDGE-1
The goal of this clinical study is to learn whether the Bridging Technique can safely and effectively treat nasolabial folds (NLF, also known as smile lines) in adults.
- Conditions
- Nasolabial Fold Correction, Facial Aging, Skin Rejuvenation, Wrinkles Such as Nasolabial Folds
- Trial name
- BRIDGING (NCT07178119)
- Testing
- (Bridging) Horizontal Cannula Technique for Treatment of Nasolabial Folds using AILEENE Vol. 2
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dr. Joseph M Novoa Libermann
Wrinkles Such as Nasolabial Folds
Post Market Study of Safety and Performance of RefillHA Volume+ for Facial Soft Tissue Augmentation and Correction of Wrinkles and Folds
This post market study was designed to collect clinical data regarding the safety and performance of RefillHA Volume+ upon its launch, from patients treated with the product in a routine clinical setting of treatments.
- Trial name
- NCT07109635
- Where
- Israel
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Glyance
Dermal Fillers
Pivotal Study to Evaluate the Efficacy and Safety of Injection With LASBEAU Strong in Correction of Nasolabial Folds
Background: Nonsurgical injectable treatments have become popular for aesthetic purposes. In recent years, cross-linked hyaluronic acid (HA) fillers containing lidocaine have been used to correct the nasolabial folds.
- Trial name
- NCT06310863
- Testing
- LASBEAU Strong or Restylane Lyft injection as hyaluronic acid fillers
- Where
- South Korea
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Nasolabial Fold Correction
Clinical Trial to Study the Efficacy and Safety of Rejeunesse Shape With Lidocaine (HA Filler) in Treating Healthy Subjects
Intend to prove the non-inferiority of Rejeunesse against the comparing medical device of Restylane Perlane in terms of improvement, efficacy, and safety of nasolabial fold on the face
- Trial name
- NCT07770789
- Testing
- Rejeunesse, Restylane Perlane
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Forest Hills Lab
Moderate to Severe Nasolabial Fold
Safety and Performance of PTMC Dermal Filler
The goal of this clinical trial is to assess the safety and performance of the PTMC Dermal filler for treating moderate to severe nasolabial folds in adult men and women.
- Trial name
- NCT06316479
- Testing
- PTMC Dermal Filler
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Aqpha Medical B.V.
Nasolabial Folds, Marionette Lines
Emervel for the Correction of Lower Face Wrinkles & Folds
This study is designed to 1. evaluate the naturalness of facial expressions in motion (2D video images), by treating investigator assessment 2.
- Conditions
- Nasolabial Folds, Marionette Lines, Wrinkles
- Trial name
- NCT02718040
- Testing
- Emervel Classic and/or Deep Treatment Group
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Nasolabial Folds, Wrinkles
TEOSYAL® RHA Ultra Deep and Perlane-L® for the Correction of Nasolabial Folds
The purpose of this study is to compare the effectiveness and safety of TEOSYAL® RHA Ultra Deep versus Perlane-L® in the treatment of moderate to severe nasolabial folds.
- Trial name
- NCT02253147
- Testing
- TEOSYAL® RHA Ultra Deep
- Where
- 4 sites in United States
- Volunteers
- 140 people
- Sponsor
- Teoxane SA
Granulomatous Disorder
Protocol for the Post-approval Study of Artefill for Correction of Nasolabial Folds
This study is a five-year, multi-center, non-randomized, non-controlled post-approval study designed to follow a total of 1000 consecutive qualified and consenting subjects treated with ArteFill® in the course of clinical…
- Trial name
- NCT03299712
- Testing
- ArteFill
- Volunteers
- 1,008 people, healthy volunteers welcome
- Sponsor
- Suneva Medical, Inc.
Nasolabial Folds
Safety Study That Compares Perlane to Perlane With Lidocaine (Perlane-L) While Correcting Wrinkles in the Area Around Your Nose
Safety study that compares Perlane to Perlane with Lidocaine while correcting wrinkles in the area around your nose.
- Trial name
- NCT00823069
- Testing
- Perlane and Perlane-L
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- Medicis Global Service Corporation
Dermatological Non-Disease
Effectiveness and Safety of Princess FILLER Lidocaine in Correction of Nasolabial Folds (NLF)
Clinical Investigation to demonstrate the effectiveness and safety of Princess Filler Lidocaine in the correction of moderate to severe nasolabial folds
- Trial name
- FILIDO (NCT03990883)
- Testing
- Princess Filler Lidocaine
- Where
- 11 sites in United States
- Volunteers
- 295 people
- Sponsor
- Croma-Pharma GmbH
Moderate-to-severe Nasolabial Folds (3-4 Level of WSRS Scores) on Both Sides of the Face
A Prospective, Multicenter, Post-marketing Clinical Follow-up Research to Evaluate the Long-term Safety of Ellansé-S Dermal Filler Made of PCL Microspheres for the Correction of Moderate-to-severe Nasolabial Folds
This research is intended to evaluate the long-term safety of Ellansé-S PCL dermal filler for the correction of moderate-to-severe NLFs. 374 subjects.
- Trial name
- NCT06243315
- Testing
- Ellansé-S
- Where
- China
- Volunteers
- 374 people, healthy volunteers welcome
- Sponsor
- AQTIS Medical B.V.
Facial Wrinkles
A Study to Compare Subject Comfort During and After Injections With the Study Products and the Safety of the Non-FDA Approved Product for the Correction of Nasolabial Folds (NLFs)
The purpose of this research study is to compare subject comfort during and after injection with NADGL and Captique® Injectable Gel, in the nasolabial folds.
- Trial name
- NCT00417469
- Testing
- NADGL
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Genzyme, a Sanofi Company