Clinical trials: Nasolabial Fold Correction
Nasolabial Folds
A Study to Evaluate the Safety and Efficacy of SYB Filler(SF-01) in the Correction of Nasolabial Folds
The objective of this clinical trial is to verify the safety and efficacy of SYB Filler (SF-01) in the temporary improvement of Nasolabial Folds.
- Trial name
- NCT03932045
- Testing
- SYB Filler (SF-01), Ellansé M
- Where
- South Korea
- Volunteers
- 59 people
- Sponsor
- Samyang Biopharmaceuticals Corporation
Nasolabial Folds
Safety and Effectiveness of JUVÉDERM™ Injectable Gel With Lidocaine
Safety and effectiveness of JUVÉDERM™ Injectable Gel with Lidocaine compared to JUVÉDERM™ without Lidocaine for procedural pain in the treatment of nasolabial folds.
- Trial name
- NCT00653861
- Testing
- JUVÉDERM™ Injectable Gel with Lidocaine, JUVÉDERM™ Injectable Gel
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Allergan Medical
Nasolabial Folds
TEOSYAL® PureSense ULTRA DEEP Versus Restylane® Lidocaine for the Correction of Moderate to Severe Nasolabial Folds in Chinese Adults
This is a prospective, multi-center, randomized, controlled, subject- and evaluator-blinded clinical investigation to demonstrate non-inferiority of TEOSYAL® PureSense ULTRA DEEP compared to Restylane® Lidocaine for the…
- Trial name
- NCT06367634
- Testing
- injection in NLF
- Where
- China
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- Teoxane SA
Nasolabial Folds
A Study to Confirm Safety and Effectiveness of RADIESSE® Injectable Implant for the Correction of Moderate to Severe Nasolabial Folds
The purpose of this study is to confirm the long-term safety, effectiveness, and degradation profile of RADIESSE® Injectable Implant for the correction of moderate to severe nasolabial folds (NLFs) in Chinese adults.
- Trial name
- Radiesse China (NCT07856797)
- Testing
- Subdermal Implant
- Where
- 8 sites in China
- Volunteers
- 163 people
- Sponsor
- Merz North America, Inc.
Nasolabial Fold
Evaluation of Collagen Dermal Filler With Lidocaine for the Correction of Nasolabial Folds
Evaluation the efficacy and safety of collagen dermal filler with lidocaine using in the middle to deep dermis for the correction of nasolabial folds.
- Trial name
- NCT03844529
- Testing
- Sunmax FULLSGEN with Lidocaine
- Where
- Taiwan
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Nasolabial Folds in Chinese Population
Efficacy and Safety of Restylane Perlane Compared to Restylane for Correction of Moderate and Severe Nasolabial Folds
The purpose of this study is to determine the safety and efficacy of using Restylane Perlane compared to Restylane for correction of moderate to severe nasolabial folds (NLF) in a Chinese population.
- Trial name
- NCT02432742
- Testing
- Restylane Perlane, Restylane
- Where
- 3 sites in China
- Volunteers
- 100 people
- Sponsor
- Galderma R&D
Aging, Premature
Safety and Performance of DKL Crosslinked Sodium Hyaluronate 23 Dermal Filler for Improvement of NLF Appearance
This is a pivotal, prospective active-controlled, randomized, double blinded (blinded evaluator and subject), intra-individual split-face comparison, non-inferiority study of DKL crosslinked sodium hyaluronate 23 versus Juvederm…
- Trial name
- NCT05021913
- Testing
- DKL crosslinked sodium hyaluronate 23, Juvéderm Volift™ with lidocaine (Allergan, Inc)
- Where
- Sweden
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Dr. Korman Laboratories Ltd.
Nasolabial Folds, Skin Aging
Transplantation of Fibroblast for Correction of Nasolabial Folds
The study evaluated the safety and efficacy of the Autologous cultured fibroblast for correction of Nasolabial folds and inhibition of skin aging
- Trial name
- NCT03140319
- Testing
- Fibroblast
- Where
- Iran
- Volunteers
- 50 people
- Sponsor
- SCARM Institute, Tabriz, Iran
Nasolabial Fold Correction
To Evaluate the Safety and Efficacy of Poly-L-lactic Acid Implants for the Correction of Nasolabial Folds
The goal of this clinical trial is to evaluate the safety and effectiveness of a poly-L-lactic acid (PLLA) dermal implant for the correction of nasolabial folds.
- Trial name
- NCT07343141
- Testing
- FUYANMEI Poly-L-Lactic Acid, Sculptra®
- Where
- Taiwan
- Volunteers
- 121 people
- Sponsor
- SciVision Biotech Inc.
Dermal Filler, Hyaluronic Acid
Evaluate the Safety and Effectiveness of Sodium Hyaluronate When Used for the Correction of Nasolabial Folds
The aim of this study is to evaluate the safety and effectiveness of pain relief of modified sodium hyaluronate gel for injection when used for the correction of moderate or severe nasolabial folds.
- Conditions
- Dermal Filler, Hyaluronic Acid, Lidocaine, Nasolabial Fold
- Trial name
- NCT04569045
- Testing
- HA+Lidocaine, HA
- Where
- 2 sites in China
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- SciVision Biotech Inc.
Correction of Moderate to Severe Nasolabial Folds
Evaluation of Pain With Belotero® Balance With Integral Lidocaine for Correction of the Nasolabial Folds
Demonstrate the effectiveness of Belotero Balance with lidocaine (Test group) for the reduction of injection-related pain in comparison to Belotero Balance without lidocaine (Control group) for the correction of NLFs.
- Trial name
- NCT03319719
- Testing
- Belotero® Balance with integral lidocaine, Belotero® Balance
- Where
- 3 sites in United States
- Volunteers
- 52 people
- Sponsor
- Merz North America, Inc.
Nasolabial Fold Improvement
Efficacy and Safety of Injection With VINCI Plus Hyaluronic Acid Filler
This clinical trial is intended to evaluate the efficacy and safety of injection with VINCI Plus as compared to Restylane-L® in correction of nasolabial fold.
- Trial name
- NCT01918839
- Testing
- VINCI Plus, Restylane-L
- Where
- 2 sites in South Korea
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- D.med
Nasolabial Fold
Tissue Repositioning Versus Tissue Support in Thread Lifting for Nasolabial Fold Correction: A Randomized, Evaluator-Blinded, Parallel-Group Controlled Trial
This randomized clinical trial compares two minimally invasive thread-lifting procedures for improving moderate-to-severe nasolabial folds, the lines that run from the sides of the nose toward the corners of the mouth.
- Trial name
- NCT07877870
- Testing
- predominantly tissue-repositioning thread lifting, predominantly tissue-support thread-lifting
- Where
- China
- Volunteers
- 182 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Facial Wrinkles
Evaluation of the Safety and Efficacy of CosmetaLife™ for the Correction of Nasolabial Folds
This is a randomized, double-blind pivotal study to evaluate the safety and effectiveness of CosmetaLife injectable dermal filler for the correction of wrinkles and folds, such as nasolabial folds (i.e., smile lines).
- Trial name
- NCT00414544
- Testing
- CosmetaLife, Restylane
- Where
- 5 sites in United States
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Cosmeta
Nasolabial Folds
Juvederm Ultra With Lidocaine Compared With Restylane for the Correction of Nasolabial Folds
Comparison of the safety and effectiveness of Juvederm Ultra with lidocaine compared with Restylane in the correction of nasolabial folds.
- Trial name
- NCT00850889
- Testing
- Hyaluronic acid gel (24 mg/mL) with 0.3% lidocaine, A gel of hyaluronic acid (concentration of 20 mg/mL)
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Allergan Medical
Nasolabial Folds
A Study Comparing Lafullen15 and Lafullen for Temporary Nasolabial Fold Improvement
The objective of this clinical trial is to verify the safety and efficacy of Lafullen15 in the temporary improvement of nasolabial Folds
- Trial name
- NCT06295172
- Testing
- Lafullen15, Lafullen
- Volunteers
- 73 people
- Sponsor
- Samyang Biopharmaceuticals Corporation
Correction of Moderate to Severe Nasolabial Folds (NLFs)
Evaluation of the Effectiveness and Safety of Radiesse for the Correction of Moderate to Severe Nasolabial Folds
Effectiveness: The purpose of this study is to demonstrate the non-inferiority of Radiesse (CaHA) to Restylane (HA) following subdermal implantation for the correction of moderate to severe facial wrinkles and folds, such as…
- Trial name
- NCT04647721
- Testing
- Radiesse injectable implant (dermal filler), Restylane injectable implant (dermal filler)
- Where
- 7 sites in China
- Volunteers
- 134 people
- Sponsor
- Merz North America, Inc.
Nasolabial Folds, Wrinkles
Study of JTM104 Injection vs. Juvederm in Treating Moderate to Severe Nasolabial Folds
Study of JTM104 Injection vs. Juvederm in Treating Moderate to Severe Nasolabial Folds
- Trial name
- NCT07265791
- Testing
- JTM104, Juvederm® ULTRA PLUS XC
- Where
- 2 sites in South Korea
- Volunteers
- 100 people
- Sponsor
- Jetema Co., Ltd.
Nasal Disease, Nasal Surgery
Medical Device Pivotal Study to Injection With SkinPlus-HYAL Implant Lidocaine vs RESTYLANE Lidocaine in of Nasolabial Folds
Purpose : This investigation intends to demonstrate that the investigational device, SkinPlus-HYAL Implant Lidocaine, is non-inferior to the comparator device, RESTYLANE Lidocaine, in terms of temporary wrinkle reduction effect…
- Trial name
- BPLUS-02 (NCT06305520)
- Testing
- Investigational medical device (SkinPlus-HYAL Implant Lidocaine), Active Comparator: Active Comparator Medical Device (RESTYLANE Lidocaine)
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Bioplus
Nasolabial Folds
A Post Market Evaluation After Treatment of Nasolabial Folds
This is an open, non-comparative study to evaluate effectiveness and safety of Restylane in correction of nasolabial folds up to 12 months after the initial treatment, and to evaluate the safety of repeat treatment of the…
- Trial name
- NCT02179736
- Testing
- Restylane
- Where
- China
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Galderma R&D