Clinical trials: Nasolabial Folds
Nasolabial Fold
Tissue Repositioning Versus Tissue Support in Thread Lifting for Nasolabial Fold Correction: A Randomized, Evaluator-Blinded, Parallel-Group Controlled Trial
This randomized clinical trial compares two minimally invasive thread-lifting procedures for improving moderate-to-severe nasolabial folds, the lines that run from the sides of the nose toward the corners of the mouth.
- Trial name
- NCT07877870
- Testing
- predominantly tissue-repositioning thread lifting, predominantly tissue-support thread-lifting
- Where
- China
- Volunteers
- 182 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Nasolabial Folds
A Study to Confirm Safety and Effectiveness of RADIESSE® Injectable Implant for the Correction of Moderate to Severe Nasolabial Folds
The purpose of this study is to confirm the long-term safety, effectiveness, and degradation profile of RADIESSE® Injectable Implant for the correction of moderate to severe nasolabial folds (NLFs) in Chinese adults.
- Trial name
- Radiesse China (NCT07856797)
- Testing
- Subdermal Implant
- Volunteers
- 163 people
- Sponsor
- Merz North America, Inc.
Nasolabial Fold
Post Market Clinical Follow up Evaluating the Performance and Safety of Juläine(TM) on Nasolabial Fold Wrinkles
The goal of this post marketing study is to verify clincal performance and safety of CE-marked device Juläine. The main objective is to evaluate device performance when used as intended for augmentation of shallow to deep…
- Trial name
- NCT06471933
- Testing
- Juläine
- Where
- 2 sites in Spain, Sweden
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Nordberg Medical AB
Nasolabial Folds
Dermal Evaluation of Facetem™ S in Nasolabial Folds Esthetics Improvement: DEFINE Study
This is a multicenter, prospective, non-randomized, uncontrolled post-market clinical follow-up (PMCF) study designed to evaluate the performance and safety of Facetem S dermal filler for the correction of moderate-to-severe…
- Trial name
- DEFINE (NCT07855224)
- Testing
- Facetem S
- Where
- 5 sites in France, Spain
- Volunteers
- 100 people
- Sponsor
- CGBio Inc.
Nasolabial Folds
Study to Assess Adverse Events and How Effective NOA LIFT is Compared to JUVÉDERM VOLIFT With Lidocaine for the Correction of Nasolabial Folds in Adults
Nasolabial folds (NLFs) are wrinkles that run from the sides of the nose to the corners of the mouth. The goal of this study is to evaluate how safe and effective NOA LIFT is compared to JUVÉDERM VOLIFT with Lidocaine for…
- Trial name
- NCT07794878
- Testing
- NOA LIFT, JUVÉDERM VOLIFT with Lidocaine
- Where
- 6 sites in China
- Volunteers
- 288 people
- Sponsor
- AbbVie
Nasolabial Fold Correction
Clinical Trial to Study the Efficacy and Safety of Rejeunesse Shape With Lidocaine (HA Filler) in Treating Healthy Subjects
Intend to prove the non-inferiority of Rejeunesse against the comparing medical device of Restylane Perlane in terms of improvement, efficacy, and safety of nasolabial fold on the face
- Trial name
- NCT07770789
- Testing
- Rejeunesse, Restylane Perlane
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Forest Hills Lab
Lips Enhancement Nasolabial Fold Correction Midface Volume Deficit
THE EVALUATION OF THE SAFETY AND PERFORMANCE OF AN INJECTABLE HYALURONIC ACID FILLER
Evaluation of the safety and performance of the investigational device in its three concentrations for cheek and lips augmentation and correction of the nasolabial folds, assuming that the performance of the product will be…
- Trial name
- NCT07763990
- Testing
- HLR-1, HLR-2, HLR-3
- Where
- 2 sites in Israel
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Hallura Ltd.
Facial Aging, Skin Aging
Hyaluronic Acid Crosslinking Clinical Study
This prospective observational case series aims to evaluate the clinical efficacy, safety, and patient satisfaction associated with hyaluronic acid dermal fillers with different degrees of divinyl sulfone (DVS) crosslinking.
- Conditions
- Facial Aging, Skin Aging, Facial Volume Loss, Facial Rhytides
- Trial name
- HACS (NCT07744464)
- Testing
- Hyaluronic Acid Dermal Fillers
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Antony de Paula Barbosa
Nasolabial Folds, Wrinkles
Study of JTM104 Injection vs. Juvederm in Treating Moderate to Severe Nasolabial Folds
Study of JTM104 Injection vs. Juvederm in Treating Moderate to Severe Nasolabial Folds
- Trial name
- NCT07265791
- Testing
- JTM104, Juvederm® ULTRA PLUS XC
- Where
- 2 sites in South Korea
- Volunteers
- 100 people
- Sponsor
- Jetema Co., Ltd.
Nasolabial Folds
Safety and Effectiveness of ELLANSÉ®-S Dermal Filler in the Treatment of Nasolabial Folds
The study will be a prospective, randomized, multi-center, split-face, controlled, double-blind clinical trial to evaluate the safety and effectiveness of ELLANSÉ®-S for the treatment of NLFs.
- Trial name
- NCT06984835
- Testing
- Ellanse S, Calcium Hydroxylapatite-based filler
- Where
- 7 sites in United States
- Volunteers
- 126 people
- Sponsor
- AQTIS Medical B.V.
Skin Aging, Facial Wrinkles
Study of the Subdermal Implant "Ultracol"
Study of the effectiveness of the medical device "Intradermal implant, sterile ULTRACOL based on polydioxanone (ULTRA V Co., Ltd., Korea) in the correction of skin contour defects.
- Conditions
- Skin Aging, Facial Wrinkles, Senile Skin Atrophy, Lipodystrophy
- Trial name
- NCT07617350
- Testing
- Administration of the prepared solution - 1 time Post injection observation - 30, 60, 160 days from the date of the first injection.
- Where
- Russia
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Estelab Clinic
Nasolabial Fold Correction
To Evaluate the Safety and Efficacy of Poly-L-lactic Acid Implants for the Correction of Nasolabial Folds
The goal of this clinical trial is to evaluate the safety and effectiveness of a poly-L-lactic acid (PLLA) dermal implant for the correction of nasolabial folds.
- Trial name
- NCT07343141
- Testing
- FUYANMEI Poly-L-Lactic Acid, Sculptra®
- Where
- Taiwan
- Volunteers
- 121 people
- Sponsor
- SciVision Biotech Inc.
Nasolabial Fold Wrinkles
CelluJuve® for the Treatment of Moderate to Severe NLFs
Single-center, open-label proof of concept study assessing the safety and effectiveness of CelluJuve® for the treatment of moderate to severe NLFs
- Trial name
- NCT07545980
- Testing
- CelluJuve®
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Spiderwort Biotechnologies Inc.
Dermal Fillers, Cheek Augmentation
Evaluation of Performance and Safety of Injectable KIO017 Device Range for Facial Tissue Filling
The goal of this clinical trial is to primarily evaluate the performance of KIO017 in filling/volumizing after injection in different areas in healthy women or men, older than 18 years and seeking an improvement of her/his face…
- Conditions
- Dermal Fillers, Cheek Augmentation, Lip Augmentation, Perioral Rhytids
- Trial name
- LITCHEE (NCT06872359)
- Testing
- KIO017-1, KIO017-2, KIO017-3
- Where
- 3 sites in France, Poland
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Kiomed Pharma
Facial Wrinkles, Anti-Aging
Safety and Efficacy Evaluation of the Monopolar Radiofrequency Device for the Improvement of Facial Wrinkles
The goal of this clinical trial is to evaluate the safety and efficacy of the monopolar radiofrequency therapy device developed by CLASSYS Inc. for improving facial and periorbital wrinkles.
- Conditions
- Facial Wrinkles, Anti-Aging, Wrinkles and Rhytides, Wrinkles Such as Nasolabial Folds
- Trial name
- NCT06657365
- Testing
- Radiofrequency (RF) Treatment with Volnewmer, Radiofrequency (RF) Treatment with Thermage CPT
- Where
- China
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- CLASSYS Inc.
Correction of Nasolabial Folds
A Clinical Investigation of the Decoria® Aesthetic Group (DAG) for Correction of Nasolabial Folds (NLF)
Decoria intense is a class III medical device and is CE-marked and has been on the market since 2014. Decoria intense is a hyaluronic acid filler that will be used according to intended use for correction of nasolabial folds.
- Trial name
- Decorate01 (NCT05235126)
- Testing
- Decoria intense
- Where
- 2 sites in Sweden
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Bohus Biotech AB
Nasolabial Folds, Wrinkles
A Prospective Clinical Investigation of DMFI300 for Treating Nasolabial Folds
This is a prospective, randomized, controlled clinical investigation designed to evaluate the performance and safety of DMFI300 for the treatment of nasolabial folds.
- Trial name
- NCT07467239
- Testing
- DMFI300, Ellansé-M
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Samyang Biopharmaceuticals Corporation
Nasolabial Folds, Wrinkles
A Prospective Clinical Investigation of DMFI150 for Treating Nasolabial Folds
This is a prospective clinical investigation designed to evaluate the performance and safety of DMFI150 for the treatment of nasolabial folds. 30 adult participants will receive a single treatment with the investigational device.
- Trial name
- NCT07292779
- Testing
- DMFI150
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Samyang Biopharmaceuticals Corporation
Nasolabial Folds, Wrinkles
Study of DIOSHA S Lido Injection vs. YOUTHFILL Fine With Lidocaine in Treating Moderate to Severe Nasolabial Folds
Study of DIOSHA S Lido Injection vs. YOUTHFILL Fine With Lidocaine in Treating Moderate to Severe Nasolabial Folds
- Trial name
- NCT07412392
- Testing
- DIOSHA S Lido, YOUTHFILL Fine with Lidocaine
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hyundae Meditech
Moderate or Severe Nasolabial Folds
Effectiveness and Safety Comparison of Lunaphil Ultra (Hyaluronic Acid, by Espad Pharmed Co.) Versus Juvederm Ultra 4® (Hyaluronic Acid, by Allergan Co.) in Nasolabial Folds (NLFs) Management
Rationale and background: Skin aging is a complex process that results in various changes in the skin, including wrinkles, sun spots, and sagging skin.
- Trial name
- NCT06509477
- Testing
- Hyaluronic acid Lunaphil Ultra (by Espad Pharmed Co.), Hyaluronic acid Juvederm Ultra 4® (by Allergan Co.)
- Where
- Iran
- Volunteers
- 104 people
- Sponsor
- Espad Pharmed