Clinical trials: Natriuretic Peptide Brain
Congenital Heart Disease, Cardiovascular Disease
Pilot Study of B-Type Natrieutic Peptide (BNP) Levels in Patients With Congenital Heart Disease(BNP)
The object of this study is to measure the levels of B-type Natriuretic Peptide (BNP) in patients with congenital heart disease, normal individuals, and patients with acquired heart failure, and compare the results from each…
- Trial name
- NCT00308230
- Testing
- Six minute walk test, Minnesota Living with Heart Failure Questionnaire
- Volunteers
- 34 people
- Sponsor
- Emory University
Pleural Effusion, Heart Failure
Comparing the Diagnostic Sensitivity and Specificity of Pleural Fluid N-Terminal Pro B-type Natriuretic Peptide (NT-proBNP) and Other Biochemical Gradient Criteria in Distinguishing Heart Failure and Non-heart Failure Related Pleural Effusions (CENTRE Study)
To assess the discriminative properties of pleural fluid (PF) N-terminal-proB-type-natriuretic-peptide (NTproBNP) levels in identifying heart failure (HF)-associated pleural effusions (PE).
- Conditions
- Pleural Effusion, Heart Failure, Malignant Neoplasm, Fluid Overload
- Trial name
- NCT05797649
- Where
- Hong Kong
- Volunteers
- 160 people
- Sponsor
- Chinese University of Hong Kong
Heart Failure
Heart Failure (HF) Assessment With B-type Natriuretic Peptide (BNP) In The Home
The HABIT clinical study is being performed to determine the benefit and optimal frequency for at home testing of B-type natriuretic peptide (BNP) for heart failure patients following hospitalization from decompensation.
- Trial name
- HABIT (NCT00946231)
- Where
- 11 sites in United States
- Volunteers
- 187 people
- Sponsor
- Abbott RDx Cardiometabolic
High Blood Pressure
Heart and Blood Pressure Study: The Effect of Aortic Impedance on Myocardial Relaxation
Does dilation of blood vessels (vasodilation), which decreases aortic stiffness, have a greater effect on heart myocardium relaxation (diastole) than vasodilation which affects mean pressure equally without improving aortic…
- Trial name
- NCT00204984
- Testing
- oral hydralazine and intravenous nesiritide
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Chest Pain
N-terminal Pro B-type Natriuretic Peptide (Nt-proBNP) Versus Exercise Test for Evaluation of Acute Chest Pain
The investigators' objective is to compare a new strategy combining clinical history and NT-proBNP levels versus the usual care, consisting of early exercise testing, for decision making in patients presenting to the emergency…
- Trial name
- NCT00493844
- Testing
- Exercise testing, Clinical evaluation + NTproBNP
- Where
- Spain
- Volunteers
- 320 people
- Sponsor
- University of Valencia
Pulmonary Embolism
Home Treatment of Patients With Pulmonary Embolism Based on Pro-Brain Natriuretic Peptide (BNP) Levels
The aim of this study is to investigate the safety of treatment of pulmonary embolism in an outpatient setting based on normal pro-BNP levels.
- Trial name
- NCT00455819
- Testing
- home treatment
- Where
- 2 sites in Netherlands
- Volunteers
- 150 people
- Sponsor
- St. Antonius Hospital
Perioperative Care
Validation of B-type Natriuretic Peptide With N-terminal Pro B-type Natriuretic Peptide in Perioperative Risk Assessment
This is a single-centre, prospective study to determine the correlation and comparative thresholds between N-terminal pro-brain natriuretic peptide (NT ProBNP, Roche) and brain natriuretic peptide (BNP, Abbott) tests.
- Trial name
- NCT05352698
- Testing
- NT ProBNP (Roche)
- Where
- Canada
- Volunteers
- 466 people
- Sponsor
- Jordan Leitch
Sepsis-induced Cardiomyopathy, the Recovery Phase of Septic Shock
Recombinant Human Brain Natriuretic Peptide for the Recovery Stage of Septic Shock
As infection control improves and circulation stabilizes, treatment de-escalation of septic shock begins, accompanied by fluid redistribution from interstitial spaces to the vasculature, increasing cardiac volume load.
- Trial name
- rh-BNP-RSS (NCT06745206)
- Testing
- Lyophilized Recombinant Human Brain Natriuretic Peptide
- Volunteers
- 30 people
- Sponsor
- Sichuan Provincial People's Hospital
Stroke, Ischemic
MidregiOnal Proatrial Natriuretic Peptide to Guide SEcondary Stroke Prevention
The present trial is addressing the question if a biologically distinct subgroup of ischemic stroke patients without known atrial fibrillation at admission, selected by a cut-off level of MRproANP concentration, which represents…
- Trial name
- MOSES (NCT03961334)
- Testing
- Dabigatran, Apixaban, Edoxaban
- Where
- 14 sites in Greece, Norway and 3 more
- Volunteers
- 620 people
- Sponsor
- University of Zurich
Supplemental Oxygen, Brain Natriuretic Peptide
Effect of Supplemental Oxygen on Perioperative BNP Concentration in Cardiac Risk Patients
The effect of supplemental oxygen on surgical site infections was already investigated in several studies before. Although, oxygen is one of the most used medical therapy in hospitalized patients, the influence on the…
- Conditions
- Supplemental Oxygen, Brain Natriuretic Peptide, Cardiac Risk Patients, Perioperative
- Trial name
- NCT03366857
- Testing
- Oxygen 30 %, Oxygen 80 %
- Where
- Austria
- Volunteers
- 260 people
- Sponsor
- Medical University of Vienna
Heart Failure, Congestive
Renal Effects of Intrarenal Nesiritide
The impact of nesiritide in CHF is unclear, but it is possible that systemic vasodilation leads to adverse consequences even if the direct renal effects are positive.
- Trial name
- NCT00270829
- Testing
- nesiritide
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Maryland, Baltimore
Congestive Heart Failure
Study to Evaluate the Safety of Twice Daily Oral Carvedilol
The objective of this study is to evaluate the long-term safety of carvedilol in pediatric patients with chronic heart failure, who completed the Pediatric Carvedilol Study 321.
- Trial name
- NCT00129363
- Testing
- Carvedilol
- Where
- 17 sites in United States
- Volunteers
- 75 people
- Sponsor
- Shaddy, Robert, M.D.
Diabetes Mellitus, Cardiomyopathy
B-type Natriuretic Peptide and Glucose Metabolism
Rationale: B type natriuretic peptide (BNP) is a hormone released from cardiomyocytes in response to myocyte stretching and serves as a reliable biomarker in the diagnosis of cardiac dysfunction and heart failure.
- Trial name
- NCT01324739
- Testing
- human BNP-32
- Where
- Austria
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Trauma, Hypovolemic Shock
Evaluation of Resuscitation Markers in Trauma Patients
Severe trauma patients have an elevated risk of multiple organ failure and death. In order to increase survival possibilities the initial treatment must be focused into resuscitation from shock.
- Trial name
- NCT02772653
- Testing
- Blood Lactate, Blood Base Excess, Blood B-type Natriuretic Peptide
- Where
- Spain
- Volunteers
- 66 people
- Sponsor
- Andrea Campos-Serra
Preeclampsia, Pulmonary Edema
Point-of-care Ultrasound Abnormalities in Early Onset Preeclampsia
The study is planned to describe the prevalence and severity of cardiac, lung and optic-nerve sheath diameter (ONSD) ultrasound abnormalities in women with early onset preeclampsia with severe features.
- Conditions
- Preeclampsia, Pulmonary Edema, Cardiac Function
- Trial name
- NCT05662995
- Testing
- Lung ultrasound
- Where
- South Africa
- Volunteers
- 60 people
- Sponsor
- University of Cape Town
Fluid Over-load
B-type Natriuretic Peptide as a Surrogate Marker Guiding Post-operative Fluid Off-loading
The long-range goal of this proposal is to decrease morbidity and mortality related to pulmonary edema and congestive heart failure (CHF) in post-operative patients.
- Trial name
- NCT01584518
- Testing
- Furosemide
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Creighton University
Diabetes Mellitus, Type 2
Effects of Rosiglitazone on Plasma BNP Levels and Left Ventricular Dysfunction
The present study aimed to evaluate the effect of rosiglitazone treatment on cardiac function compared with metformin
- Trial name
- NCT00300911
- Testing
- Rosiglitazone(drug), cardiac adverse effects
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Baskent University
Diastolic Heart Failure
Study of Nesiritide in Diastolic Heart Failure.
We hypothesize that nesiritide will have favorable effect in decreasing heart filling pressures and echocardiogram studies.
- Trial name
- NCT00309868
- Testing
- neseritide
- Volunteers
- 20 people
- Sponsor
- Massachusetts General Hospital
Respiratory Insufficiency
B-type Natriuretic Peptide for the Management of Weaning
Several clinical findings and clinical trials have suggested that the prognosis of intensive care unit (ICU) patients may be improved by minimizing the positive fluid balance.
- Trial name
- BMW (NCT00473148)
- Testing
- BNP-guided weaning, Standard physician-directed weaning
- Where
- France
- Volunteers
- 265 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Chest Pain, Coronary Artery Disease
Risk Markers in the Acute Coronary Syndromes
The main aim of this trial is to assess the long-term prognostic value of different types of Factor XIIa in an unselected, single center series of 871 chest pain patients admitted to the emergency unit, employing blood samples…
- Conditions
- Chest Pain, Coronary Artery Disease, Unstable Angina Pectoris, Myocardial Infarction
- Trial name
- RACS (NCT00521976)
- Where
- Norway
- Volunteers
- 871 people
- Sponsor
- Helse Stavanger HF